Wake-up (Presentation Mode)

1. What type of cells are produced in meiosis?

2. Brown eyes is dominant to blue eyes. A blue eyed woman marries a man who is a carrier. They want to have blue eyed children. How much of a chance do they have of that happening?

Wake-up #2Brown eyes (B) is dominant to blue eyes (b). A blue eyed woman marries a man who is a carrier. They want to have blue eyed children. How much of a chance do they have of

that happening?

Bb x bbb b

B

b

Bb Bb

bb bb

50% chance

Karyotypes

Christopherson

Human Genetics: Karyotypes

46 TOTAL

23 homologous

pairs

46 TOTAL

23 homologous

pairs

Sex Chromosomes

• 2 sex chromosomes• Typical Female = XX• Typical Male = XY

Autosomes

Autosomes: Any

chromosome that’s not a sex chromosome

•44 Autosomes•22 pairs of Autosomes

What is a Karyotype?Number and appearance of chromosome set

Understanding a KaryotypeHomologous pairs

Sex Chromosomes

Autosomes

How to Read a Karyotype1. Look for homologous pairs in autosomes

How to Read a Karyotype2. Check for 2 sex chromosomes

Nondisjunction

Failure of the chromosomes to

separate properly during

meiosis

Monosomy (Write below Monosomy in chart)

Mono – One

Missing a chromosome

1 instead of 2 chromosomes

Gamete Gamete

Zygote

Turners SyndromeXO-Single X chromosome

Turners Syndrome Symptoms

Watch video linked above to see the many

faces of Turners Syndrome.

Trisomy(Write below Monosomy in chart)

Tri – Three

Having an extra chromosome

3 instead of 2 chromosomes

Gamete Gamete

Zygote

Down SyndromeAka: Trisomy

21

There is an extra 21st

chromosome

Trisomy 21 Symptoms

Watch video linked above to

learn more about Trisomy

21.

Klinefelters SyndromeThere is an sex chromosome; XXY

Klinefelter’s SymptomsWatch video

linked above to learn more

about Klinefelter’s syndrome.

Nondisjunction and Chromosomal Disorders

Watch video

Analyzing Karyotypes

Examine the karyotypes on the back of your notes; using your knowledge identify

the following for each:

a. The sex of the personb. The chromosomal disorder or normal

Klinefelters; Male

Normal Male

Trisomy 21; Female

Karyotype activity

Ask the substitute for the Karyotype activity. On the Wiki, click on the activity link for the day.

Build the Karyotypes by first matching the numbered chromosomes in the correct spot on the karyotype.

Second, find the homologous pair for each numbered chromosome by matching up patterns.

Last, answer the questions on the activity sheet.