vol. 215 journal of controlled release 10 october 2015

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OFFICIAL JOURNAL OF THE CONTROLLED RELEASE SOCIETY AND THE JAPANESE SOCIETY OF DRUG DELIVERY SYSTEM VOLUME 215, 10 OCTOBER 2015 ISSN: 0168-3659 COVER STORY Enhanced regeneration capacity of cardiac stem cells by TAT-Hsp27

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OFFICIAL JOURNAL OF THE CONTROLLED RELEASE SOCIETYAND THE JAPANESE SOCIETY OF DRUG DELIVERY SYSTEM

VOLUME 215, 10 OCTOBER 2015 ISSN: 0168-3659

COVER STORYEnhanced regeneration capacity of cardiac stem cells by TAT-Hsp27

Vol. 215 JOURNAL OF CONTROLLED RELEASE 10 OCTOBER 2015

CONTENTS

Cited in: BIOSIS/Biological Abstracts; CAB Abstracts; Chemical Abstracts Services; Current Contents (Life Sciences); EMBASE/Excerpta Medica; International Pharmaceutical Abstracts; PUBMED/MEDLINE/Index Medicus; Polymer Contents; Science Citation Index. Also covered in the abstract and citation database Scopus®. Full text available in ScienceDirect ®

Available online at www.sciencedirect.com

05054

Editorial A New Asia Associate Editor

K. Park A1

Cover Story Enhanced regeneration capacity of cardiac stem cells by TAT-Hsp27

K. Park (West Lafayette, USA) 129

Reviews Potential mechanisms and applications of statins on osteogenesis: Current modalities, conflicts and future directions

A. Oryan, A. Kamali and A. Moshiri (Shiraz, Tehran, Iran) 12 Future prospect of insulin inhalation for diabetic patients: The case of Afrezza versus Exubera

M.M. Al-Tabakha (Al Ain, United Arab Emirates) 25 Life in 3D is never flat: 3D models to optimise drug delivery

K.A. Fitzgerald, M. Malhotra, C.M. Curtin, F.J. O' Brien and C.M. O' Driscoll (Dublin, Ireland) 39 Cardiac gene therapy: Recent advances and future directions

D. Mason, Y.-Z. Chen, H.V. Krishnan and S. Sant (Pittsburgh, USA) 101 Silk as a potential candidate for bone tissue engineering

F. Mottaghitalab , H. Hosseinkhani , M.A. Shokrgozar , C. Mao , M. Yang and M. Farokhi (Tehran, Iran; Taipei, Taiwan;Norman, USA; Zhejiang, China) 112

Research Papers Circumventing the blood–brain barrier: Local delivery of cyclosporin A stimulates stem cells in stroke-injured rat brain

A. Tuladhar, C.M. Morshead and M.S. Shoichet (Toronto, Canada) 1 Intracellular transduction of TAT-Hsp27 fusion protein enhancing cell survival and regeneration capacity of cardiac stem cells in

acute myocardial infarction H.J. Kim, M.-H. Kim, J.T. Kim, W.-J. Lee, E. Kim, K.S. Lim, J.K. Kim, Y.I. Yang, K.D. Park and Y.-H. Kim (Busan, Seoul, Suwon,Republic of Korea) 55

Live imaging of transgene expression in Cloudman S91 melanoma cells after polyplex-mediated gene delivery M.O. Durymanov , A.V. Yarutkin , Y.V. Khramtsov , A.A. Rosenkranz and A.S. Sobolev (Moscow, Russia) 73

Inhibition of cisplatin-resistance by RNA interference targeting metallothionein using reducible oligo-peptoplex J.-H. Lee, J.-W. Chae, J.K. Kim, H.J. Kim, J.Y. Chung and Y.-H. Kim (Seoul, Republic of Korea) 82

Dual-targeting nanocarrier system based on thermosensitive liposomes and gold nanorods for cancer thermo-chemotherapy M. Yu , F. Guo , F. Tan and N. Li (Tianjin, China) 91

Graphical Abstracts Contents Listing $doi: 10.1016/S0168-3659(15)00686-0 e1

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