vitamin ```k```. history of discovery in 1929,danish scientist henrik dam investigated the role of...

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Page 1: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

VITAMIN

```K```

Page 2: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

History of discovery

in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted diet.after several weeks,the animals developed hemorrhages and started bieeding.these defects could not be restored by adding purified cholesterol to the deit.it appeared that-thogether with the cholesterol-a second compound had been extracted from the food,and this compound was called the coagulation vitamin.the new vitamin received the letter k beacause the initial discoveries were reported in a German journal,in which it was designated as koagulationsvitamin.Edward Adelbert Doisy of Saint Louis University did much of the structure and chemical nature of vitamin k.Dam and Doisy shared the 1943 Nobel prize for medicine for their work on vitamin k published in 1939.several laboratories synthesized the compound in1939.

Page 3: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 4: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 5: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 6: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

Blood coagulation

Page 7: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 8: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 9: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

arthritis

Page 10: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

osteoporosis

Page 11: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 12: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 13: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 14: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 15: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 16: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted
Page 17: VITAMIN ```K```. History of discovery in 1929,Danish scientist Henrik dam investigated the role of cholesterol by feeding chickens a cholesterol-depleted

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