A N N U A L R E P O R T 2 0 1 4

Vision Restored. Lives Reclaimed.

Bringing Patients Back Into the Light

As Boston Foundation for Sight moves into its third decade, we are proud that awareness and acceptance of BostonSight® PROSE treatment continues to build. This has been fostered by the success of our provider network and a rapidly growing body of peer-reviewed publications that attest to the value of PROSE for treatment of complex corneal disease.

PROSE treatment is successful in 95 percent of those who receive it. For so many patients, it offers a way back into the light. We are gratifi ed by the knowledge that our leadership and—dare we say it—vision have created a vibrant community of ophthalmologists and optometrists who treat patients around the world.

Moreover, we continue to invest resources in a number of areas to restore vision and help our patients reclaim their lives. First, we are committed to offering fi nancial aid to those who need it—patients who will otherwise be denied PROSE treatment. Also, we must continue to provide education and training to ophthalmologists and optometrists, while conveying to patients—and their families—that they can live full lives despite their diffi cult diagnoses. Finally, we aim to advance innovation in the design, customization and overall approach to PROSE treatment.

With the goal of growing BFS responsibly, we have developed fi ve funding priorities, which are featured in this Annual Report. These priorities refl ect a commitment by our team at Boston Foundation for Sight—talented people who provide the compassionate care that is the hallmark of BFS. People make the difference here. That includes our great patients who support and nurture each other, and donate generously to help others gain access to PROSE treatment.

Boston Foundation for Sight cannot meet the major challenges we face without your support. Vision is precious; it is the sense that we value most. With your help, we can provide a greater number of individuals with a way back into the light.

Sincerely,

Eugene A. Bonte Gary A. KnaakPresident and CEO Chairman, Board of Directors

PAGE 1

Fundraising Goal:

Enhancing Our Medical Education and Training Programs

Expanding and Supporting the BostonSight® Network

Key Accomplishments for 2014

• Boston Foundation for Sight provided more than $634,110 in fi nancial assistance to 168 patients at the Needham, Massachusetts center and an additional $97,500 in assistance to patients within the U.S. provider network.

• More than 1,175 patients worldwide received BostonSight® PROSE treatment.

• The Boston Foundation for Sight lab manufactured a total of 9,500 devices in support of PROSE treatment.

• The University of Rochester Flaum Eye Institute joined the BostonSight® Network.

• Boston Foundation for Sight held its second BostonSight® PROSE User Group meeting at the American Academy of Ophthalmology annual meeting.

• Boston Foundation for Sight continued its tradition of welcoming adults and children with Stevens Johnson syndrome to the fi fth annual SJS Care Week.

• Over the last 25 years, 41 peer-reviewed publications have attested to the impact of PROSE treatment. Twenty-one of those were published in the last fi ve years— triple the number from the previous fi ve years.

Steve Corlett (left),

director of lab operations,

and Manoel Carvalho,

lab manager, assure the

highest quality in the

manufacture of

PROSE devices.

PAGE 2

Each life has hurdles to be faced and endured. Karen-Lee Simpson has faced numerous, life-threatening hurdles—notably, multiple serious diagnoses that dominated her life for more than a decade. Ms. Simpson survived chronic myelogenous leukemia, years of chemotherapy, a stem cell transplant and a long list of other medical problems and complications. On top of these issues, she faced constant pain due to her severely dry eyes.

“The pain began in 2004, a few years after my stem cell transplant, and it was debilitating,” says the Nashua, New Hampshire, resident. “Most nights I woke out of a sound sleep because the pain in my eyes was too much to bear. I had to put drops in my eyes every 15 minutes.”

Ms. Simpson’s life also was limited by diminishing vision, so that she could no longer sing in her church choir and was barely able to drive. “There were aging relatives I hadn’t seen in years and who I missed so much,” she says. “But I couldn’t get to them. I depended on other people to drive me where I needed to go, including Dana-Farber Cancer Center for treatment.”

One day while sitting in a waiting room at Dana-Farber and placing drops in her burning, painful eyes, she received the answer to her long-standing problem. “A man sitting across from me said ‘I have something to show you,’” she recalls. “He removed a PROSE device from his eye, mentioned Boston Foundation for Sight, handed me Dr. Jacobs’s business card and said ‘they’ll help you.’”

Despite the roadblock of fi rst needing cataract surgery, Ms. Simpson was soon in an exam room with Deborah S. Jacobs, MD, BFS medical director, who inserted a pair of trial PROSE devices and encouraged her to spend some time walking around.

“I had such clarity of vision that I realized I had been virtually blind,” says Ms. Simpson. “Within 20 minutes, all the pain was gone. It was amazing; I was overjoyed.”

BFS provides funds to pay for treatmentHer initial introduction to PROSE treatment was followed by the customization process, which was performed by Alan Kwok, OD. He has treated many patients who suffer from extremely dry eyes. “Whether someone has ocular graft-vs-host disease due to a stem cell tranplant or severe dry eye caused by other medical conditions, when the lacrimal gland no longer produces tears, the eye becomes light-sensitive, extremely irritated and red—like a war zone,” Dr. Kwok explains. “Artifi cial tears will help, but for less than fi ve minutes. As soon as someone begins wearing PROSE devices, the eyes quiet down because the environment over the corneas is how it should be.”

Indeed, Ms. Simpson’s eyes responded quickly, and—motivated to return to a full life—she learned to apply and remove her PROSE devices in no time. “Before going to Boston Foundation for Sight, I went on YouTube and watched their training videos so that I would be ready for life with PROSE devices,” she says.

There was another important detail: Ms. Simpson’s health insurance would not cover the cost of her PROSE treatment. However, BFS covered more than half the total cost. One of the organization’s top funding priorities is raising additional funds to cover the cost of PROSE treatment for those who will otherwise be unable to receive it. Those days at BFS had an impact on Ms. Simpson. “I met people from all over the world and from all walks of life who found BFS through word of mouth or a prayer,” she says. “I began to realize how much pain I had been in—for nine years—and how much energy it took to live my life.”

Another hurdle to climbBack home again, Ms. Simpson prepared to drive to her daughter’s home for Thanksgiving. “I hadn’t been able to drive on the highway in years,” she says. After she arrived that evening, Ms. Simpson suffered an accident that seems incomprehensible: she tripped on the hem of her nightgown as she headed down the stairs, fell and broke her hand and wrist, bruised ribs and tore both rotator cuffs.

Out of Severe Eye Pain and Busy AgainNew Hampshire Resident Is No Longer

Defi ned by Her Eye Problem

PAGE 3

“I was lucky to be alive, but I cried for two weeks,” she says. During her rehabilitation, which stretched to more than a year, Ms. Simpson was unable to insert or remove her PROSE devices. “The people at Boston Foundation for Sight suggested I put them in dry dock until my hand worked again.” By March 2014, Ms. Simpson was back to wearing her devices and is more grateful than ever.

“I’m busy again and loving it,” she says, noting that her life is full—with providing counseling services, making jewelry, working out and participating in a TV program that is in development. “The theme is people who have overcome adversity.”

Ms. Simpson knows a lot of about that. Being diagnosed with leukemia and getting through a long, diffi cult treatment regimen was tough enough. “Along the way, I suffered a stroke, had several surgeries, developed

diabetes, was diagnosed with kidney cancer, had double-pneumonia twice and was in a coma for ten days,” she says. “While I was battling the leukemia and everything else, my eyes came second.”

This is a familiar scenario at BFS, says Dr. Kwok. “When patients have battled for their lives due to cancer, as Ms. Simpson did, they learn to cope with their other problems,” he observes. “They’ve been through so much; they tend to handle the challenge of their serious eye pain.”

“For more than nine years, my eye problem defi ned me as a person,” says Ms. Simpson. “But no more. Now, whenever I get the opportunity to tell someone about Boston Foundation for Sight, I pass it on.”

Funding Goal #1:

Providing Financial Assistance to Those Who Need Treatment

“I’m busy again and loving it,”

says Karen-Lee Simpson of

Nashua, New Hampshire, who

now enjoys making jewelry

thanks to PROSE treatment.

The Patient and Family Support Center

The Kitchen: The Heart and Soul of BFS

PAGE 4

It’s not a waiting room. It is a community gathering place where long-standing friendships begin and experiences are shared.

People stop in for coffee, a snack or a meal, but they also go there to relax and refl ect. For many, it is where they realize that PROSE treatment is going to provide a way back into the light. The Patient and Family Support Center—also known as “the kitchen”—is the heart and soul of Boston Foundation for Sight.

“It is the fi rst place I stop on my visits to BFS,” notes Gary Knaak, BFS board chair, who is also a patient.

“We usually suggest that patients spend time in the center during their PROSE device wearing assessments,” says Karen Carrasquillo, OD, PhD, director of clinical care. “While they are there, patients often meet someone who is already benefi tting from PROSE treatment, and they become hopeful, too.

“For patients with similar conditions, the kitchen becomes a forum for conversation,” she notes. “They develop a sense of belonging.”

That is especially true each summer, when SJS Care Week is held at Boston Foundation for Sight, and patients with Stevens Johnson syndrome (SJS)—children and adults alike—fi ll the room.

Funding Goal #2:

Growing Our Patient and Family Fund

PAGE 5

“Everyone gathers around the table, and we catch up the way a family does,” says Mariam Khawam, who travels from Chicago to attend the annual event at BFS. “It’s like a reunion, but you meet new people.”

Ms. Khawam also knows the kitchen as a quiet place, which is what she needed when she fi rst came to BFS, accompanied by her mother and brother, in 2011. A college freshman at the time, she had been diagnosed with toxic epidermal necrolysis (TENS), a variant of SJS, and had almost given up hope for regaining her vision.

“When I fi rst had PROSE devices inserted, I started crying because I saw my mother’s face for the fi rst time in two years,” she recalls.

Later on, in the kitchen, Ms. Khawam began to relax. “That’s where the healing started,” she says. “Pretty soon I was talking with other patients—people from around the world who had diagnoses I’d never heard of. We learn so much from each other, mostly how our eye problems left us emotionally drained.”

The Patient and Family Support Center is stocked with food and beverages and becomes an oasis for individuals who come to Boston Foundation for Sight to get their lives back. In the kitchen, patients refl ect on their experience, make friends and are less alone.

That is the point, says Dr. Carrasquillo. “The center originally was established because so many patients come to Boston Foundation for Sight from outside the region. They needed a place to spend time. It has evolved to become so much more than that. So many long-lasting friendships have started there.”

The Patient and Family Support Center often serves as a forum for conversation where long-lasting friendships begin.

PAGE 6

NETWORK EXPANSION BENEFITS MANYTalented PROSE Doctors Head Off to New York and Texas

The dual goals of expanding the BostonSight® Network and providing clinical

education on PROSE treatment are closely linked. A steady stream of talented cornea

fellows and optometry residents comes to Boston Foundation for Sight to learn about

the treatment of complex corneal disease and the benefi ts of PROSE treatment.

Future PROSE providers from around the country also come to BFS for intensive

training as PROSE clinical fellows.

The most recent PROSE clinical fellow, Major Kelly Olson, OD, MBA, was selected to undertake the nine-week training when Lieutenant Colonel Evelyn Reyes-Cabrera, OD, who had served as the PROSE provider at Brooke Army Medical Center (BAMC) in San Antonio, Texas, was reassigned. Dr. Olson is director of optometry education programs at BAMC and now spends about half his time seeing PROSE patients (see page 8).

The BostonSight® Network added a twelfth U.S. site—the third in New York—when Flaum Eye Institute became a PROSE provider in late 2014. The story of how the respected eye institute, which is located at the University of Rochester Medical Center, joined the BostonSight® Network is unique. In addition to the presence of outstanding cornea specialists, Flaum Eye Institute is the site of research that may expand the application and use of PROSE treatment (see page 10). Moreover, a grateful and generous patient who received PROSE treatment in 2008 made a gift to underwrite the startup costs associated with Flaum joining the network.

“This was the fi rst time that research was part of the motivation to launch a new site,” notes Ilene Knopping, director of the BostonSight® Network. “Dr. Yoon has been investigating the potential for expanding the capabilities of PROSE treatment to improve vision in patients with higher order aberrations [HOA].” In the past, Geunyoung Yoon, PhD, director of the Yoon Lab at Flaum, has traveled to BFS to conduct clinical research on patients whose vision is limited by HOAs, complex deviations from normal vision that often occur in those with keratoconus. Dr. Yoon has developed innovative ways to measure these aberrations and, in an ongoing collaboration with BFS, found ways to incorporate HOA corrections into PROSE devices.

James Aquavella, MD, a cornea specialist at Flaum, has been eager to offer PROSE treatment at the busy, diverse institute. “I see patients with complex corneal disease and have referred them to Boston Foundation for Sight,” says Dr. Aquavella. “I know that PROSE treatment is a great benefi t to them; it’s been my goal for several years to incorporate PROSE here at Flaum.”

In addition to the presence of

outstanding cornea specialists,

Flaum Eye Institute is the site of

research that may expand

the application and use of

PROSE treatment.

Funding Goal #3:

Expanding and Supporting the BostonSight® Network

PAGE 7

A grateful PROSE patient makes a generous giftThe chorus of support for Flaum to join the BostonSight® Network included Joseph Hanna, one of Dr. Aquavella’s patients. “Joe has a unique form of ocular surface disease,” he explains, noting that he tried several different treatments to address Mr. Hanna’s painful dry eyes, to no avail. “In 2008, we sent him to Boston Foundation for Sight so that he could receive PROSE treatment.”

“My vision was fi ne,” Mr. Hanna explains. “By healing the ocular surface, PROSE had an impact on my quality of life; the treatment was very effective. In fact, the entire experience at Boston Foundation for Sight was positive. The staff is so dedicated, and they were very good to me.”

Before long, Mr. Hanna—a member of the Flaum Eye Institute Board of Trustees—was involved in discussions about Flaum joining the BostonSight® Network. “I saw what PROSE treatment did for me,” Mr. Hanna says. “I have friends with eye problems, and their lives are diminished as a result.” He, Dr. Aquavella and Dr. Yoon all lobbied to bring PROSE treatment to Flaum.

Soon Mr. Hanna, who has made gifts to BFS, as well as Flaum—to support Dr. Aquavella’s lab and the ongoing ocular surface research—offered to underwrite the costs associated with launching a PROSE site, which allowed the institute to move forward. The fi rst step was for Dr. Aquavella to recruit an optometrist who was enthusiastic about providing PROSE treatment. He succeeded in recruiting Tara Vaz, OD, who brought an outstanding background that includes research.

“By healing the ocular surface,

PROSE had an impact on my

quality of life; the treatment was

very effective.”

—Joseph Hanna

Flaum Eye Institute (FEI) now has a

PROSE treatment exam room, thanks to a

generous gift from Joseph and Linda Hanna.

Gathering to see the new room are

(left to right) Tara Vaz, OD,

Steven Feldon, MD, FEI director,

Mr. Hanna, James Aquavella, MD, and

Geunyoung Yoon, PhD.

“I knew of PROSE treatment and have always been interested in it,” says Dr. Vaz. “I was eager to expand my depth of knowledge, and the research component at Flaum Eye Institute attracted me.”

Training at BFS: invigorating, challenging and inspiring Dr. Vaz was impressed with everything she observed during her nine-week intensive training at BFS. “I was struck by how everyone works in tandem,” she says. “The turnaround in the lab’s ability to manufacture PROSE devices is phenomenal. It was an invigorating and challenging experience for me; I had to be on my toes at all times while I was at BFS. I learned so much.”

Like all PROSE providers, Dr. Vaz has patients she won’t forget. “During my training, I treated a patient who suffered from Stevens Johnson syndrome and had persistent epithelial defect,” she says. “Multiple treatments had failed. But PROSE treatment worked, and she was so thankful.”

When Dr. Vaz returned to Flaum Eye Institute, she began following existing PROSE patients, as well as consulting on cornea clinic patients who are candidates for the treatment. “In the early months, there were situations where I needed assistance with customizing devices and obtaining insurance coverage for patients,” she says. “They are so supportive. I have everyone’s direct line at Boston Foundation for Sight.”

Dr. Vaz says she is eager to help spread the word about PROSE. “Too many cornea specialists—ophthalmologists and optometrists—don’t know what PROSE offers patients,” she says. “I have found out how rewarding it is to provide this treatment.”

A lot happened at Flaum Eye Institute in 2014 thanks to the decision to join the BostonSight® Network. Promising research is being supported, new research is being planned, and individuals living in the Rochester area who need PROSE treatment can turn to their trusted and prestigious local eye institute. “I’m pleased that my gift has had an impact on the quality of life of other people,” says Mr. Hanna, who continues to be impressed with the BFS staff. “Ilene Knopping does an excellent job in coordinating the support at network sites.

“People are benefi ting from having PROSE treatment available in Rochester, and that makes me happy.”

A Unique Mission at Brooke Army Medical Center

Major Kelly Olson, OD, MBA, Saw Miracles Happen at BFS

At Brooke Army Medical Center, Major Kelly Olson, OD, MBA, and his colleagues see a diverse population of patients—not only current and retired soldiers, but also their spouses and children. “We have the unique mission of supporting war fi ghters by making sure they are ready to go to war and into harm’s way,” says Dr. Olson.

A certain number of them, such as soldiers who have suffered facial/ocular burns, are candidates for PROSE treatment. After nine weeks of training at BFS, Dr. Olson is prepared to provide it. “The doctors at Boston Foundation for Sight who trained me were excellent,” he says. “I was impressed with the precision used to produce PROSE devices and, from the time I arrived at BFS, surprised at the frequency

PAGE 8

Funding Goal #4:

Enhancing Our Medical Education and Training Programs

of severe cases they see there. I received a tremendous education through my observation and interaction with these patients.”

Dr. Olson says he felt a bit spoiled by the fi rst patient he treated. “She was a sweet woman from Vermont who had been struggling for a long time with dry eyes,” he recalls. “We put the PROSE devices in her eyes, and she was completely overwhelmed by the improved vision and reduction in her pain.

“She started crying, and there were hugs all round. For me, it set the stage for the kinds of miracles that occur at BFS. When I was there, I called my family every night, and my kids would say to me ‘Dad, who did you help today?’ Providing PROSE treatment is among the greatest things I’ve done in my career.”

Making friends in IraqAs a military optometrist, Dr. Olson has traveled throughout the country and the world, including to Iraq, where he was based at Camp Anaconda during 2005-2006. The base camp, located 40 miles north of Baghdad, was one of the largest U.S. military bases during the war.

Leaving base camp put Dr. Olson at risk for being mortared or bombed. “In Ramadi, I saw soldiers come in with catastrophic injuries and did would I could to help, even if it was just donating blood,” he says. “You develop respect and reverence for those soldiers who sacrifi ce their lives.”

Dr. Olson found an unexpected role to play while in Iraq. “I was aware of children who had lost an eye,” he says. “I took an elective course on fabricating prosthetic eyes when I was in optometry school, never knowing if I would ever use that skill.”

PAGE 9

Working with a local dentist who made teeth, Dr. Olson created prosthetic eyes for 24 children. “Needless to say, in addition to improving the quality of life of those kids, this became a source of goodwill with the local sheikhs and tribal leaders in the area, who brought their children to us,” Dr. Olson recalls. “I made 24 friends in Iraq.”

He also made plenty of friends during his training at BFS. “I consider everyone at BFS to be my friends, as well as my colleagues,” he says. “I know that if I need their help with a clinical problem, they’ll be there to solve it. Mostly, I will never forget the compassion they have for their patients.”

“When I was at BFS,

I called my family

every night, and

my kids would say to

me ‘Dad, who did

you help today?’”

—Major Kelly Olson, OD, MBA

PAGE 10

RESEARCH ON PROSE IS INCREASINGLY DIVERSEMany Studies Are Performed at BostonSight® Network Clinics

As more people continue to benefi t from PROSE treatment, the amount of research devoted to PROSE has steadily increased. Past research provided clear evidence of the treatment’s impact on those with complex corneal diseases. Current research, including investigations underway during 2014, aims to expand the use of PROSE treatment to benefi t more individuals and to make the customization of PROSE devices a quicker, more effi cient process, which will reduce the number of visits patients are required to make.

Publishing research is a good way to increase awareness and acceptance of PROSE treatment—an important focus for Deborah S. Jacobs, MD, from the time she arrived as medical director in 2006. “In 2007, two different studies were pub-lished on patients with ocular graft-vs-host disease, which was followed in 2008 by a study on our pediatric experience with PROSE,” Dr. Jacobs notes.

“By 2010, the fi rst truly prospective study—one that followed a group of patients over time—was published. This project, conducted in collaboration with the Schneider Institutes for Health Policy at Brandeis University, measured the impact of PROSE treatment on patients and established its cost-effectiveness.”

More recently, Dr. Jacobs has worked with Joshua Agranat, a student at Boston University School of Medicine who has an interest in ophthalmology, on a study of the fi ve-year impact of PROSE treatment, which shows that it offers continued benefi t as defi ned by improved visual function in patients with complex corneal disease. “Josh’s work was selected for presentation at the 2013 Cornea Society/Eye Bank

At the University of Rochester’s Flaum Eye Institute, which joined the BostonSight® PROSE Network in December (see page 6), research on improving vision with PROSE treatment continues in the lab of Geun-young Yoon, PhD. Dr. Yoon has developed innovative ways to measure higher order aberrations (HOA), vision problems beyond nearsightedness, farsightedness or astigmatism that occur in many patients with keratoconus and can be challenging to correct. Before Flaum was part of the network, Dr. Yoon and a post-doctoral fellow came to BFS to explore the feasibility of making optical adjustments in PROSE devices to improve vision in this patient population.

“PROSE devices can correct HOAs, which interfere with fi ner vision,” explains Dr. Jacobs. “Some keratoconus patients can’t be fully corrected with ordinary contact lenses despite a clear cornea, and PROSE devices have great potential. Our colleagues at Flaum, led by Dr. Yoon, are helping push this boundary by extending this collaborative work dating back more than fi ve years. Like him, we want keratoconus patients to get to 20/20 vision.“

Now that Tara Vaz, OD, is providing PROSE treatment at Flaum, Dr. Yoon has the on-site support he needs to customize devices for his research. Moreover, patients can now be treated and monitored at Flaum.

Elsewhere at Flaum, James Aquavella, MD, a cornea specialist, has a longstanding research interest in the ocular surface and sees potential for PROSE devices for patients who have an artifi cial cornea, called a keratoprosthesis. “In some of

Association Fall Educational Symposium meeting,” says Dr. Jacobs, adding that his abstract received second prize. His report also was selected by the American Academy of Ophthalmology for presentation at its annual meeting in October 2014.

Research may lead to expanded use of PROSE devicesThe number of peer-reviewed scientifi c publications on PROSE treatment continues to rise, thanks to the efforts of investigators within BFS’s BostonSight® Network. “This is a strong trend at several of the network sites, where our colleagues have published some outstanding papers,” says Dr. Jacobs. “Their independent research validates what we do at BFS and further increases awareness of PROSE treatment.”

The fi rst network paper appeared in 2010, when colleagues at Alkek Eye Center, Baylor College of Medicine, published a paper on PROSE treatment for patients with neurotrophic keratitis due to shingles. Since then, numerous other reports have emerged, including from investigators at Brooke Army Medical Center in San Antonio, Texas; at the USC Eye Institute in Los Angeles, California; and at Sankara Nethralaya and L.V. Prasad Institute, both in India.

In 2014, clinicians at the Kellogg Eye Center in Ann Arbor, Michigan, published a particularly impressive paper, says Dr. Jacobs. “Their research showed that PROSE treatment compares favorably, in terms of outcomes and risks, to corneal transplantation,” she explains. “Also, in approximately 26 percent of cases where commercial scleral lenses were unsuccessful, PROSE treatment was proven to work.”

PAGE 11

these patients, the surface of the eye is vulnerable, and their visual acuity is poor,” says Dr. Aquavella. “We are considering studying the use of PROSE devices on top of the artifi cial cornea to protect the eye.”

Progress continues on image-guided customization The quest to shorten the current, iterative process of customizing PROSE devices through the use of ocular imaging is well underway. The goal of this research, now overseen by Chirag Patel, OD, is to simplify the customization process using optical coherence technology (OCT) or laser scanners to generate a 3D image of the eye. These imaging tools are being developed with grant support from the Small Business Innovation Research program.

“Two companies currently are working on the instruments,” says Dr. Patel, who joined BFS in 2014. “Obtaining a comprehensive image requires stitching multiple scans together, and we need to scan portions

of the eye beneath the eyelids. However, scanning the eye is a challenge, because the eye is in constant motion, and some of our more complex patients have diffi culty even opening their eyes.”

The hope is that more accurate scanning data will result in a better starting point for customization of PROSE devices, ultimately requiring less time, fewer cuts in the lab and less cost to both the patient and BFS.As part of the upcoming clinical trial, which is scheduled to begin in mid-2015, several PROSE patients will be scanned with one of these instruments to determine how image-guided PROSE devices compare to those produced through the traditional customization method.

“If successful, the goal would then be to make this technology available for use during the customization of new PROSE devices in Needham and throughout our network,” notes Dr. Patel.

“We continue to innovate at Boston Foundation for Sight,” says Dr. Jacobs. “There is no question that philanthropic support directed to research helps us. For example, the important Brandeis collaboration, which established the clinical and cost-effectiveness of PROSE treatment, was supported by a donation.

“Making a gift that supports research is another way to ensure the future—and the growth—of this important technology,” she adds. “It may take a few years to see the results, but fertilizing our research will bear fruit that ultimately will benefi t many people.”

Funding Goal #5:

Developing Key Treatment Innovations through Clinical Research

Deborah S. Jacobs, MD, medical director,

and Chirag Patel, OD, discuss data related

to the image-guided customization research

underway at BFS.

PAGE 12

INCOME: Needham clinic revenue, net* $ 3,105,238 Network provider clinic revenue, net* 2,136,430 Contributions 509,578 Rental 300,000 Other 73,786 Total income $ 6,125,032 EXPENSES: Program services $ 4,269,403 Management and general 1,260,310 Rental 302,753 Fundraising 431,049 Total expenses $ 6,263,515

Net income (loss) $ (138,483)

December 31, 2014 December 31, 2013

$ 3,467,850 2,304,900

686,700300,000

163,429$ 6,922,879

$ 4,091,546

1,507,816304,474 421,883

$ 6,325,719

$ 597,160

2 0 1 4 I N C O M E A N D E X P E N S E S

The information above has been extracted from the IRS form 990 and the fi nancial statements of Boston Foundation for Sight for the years ended December 31, 2014 and 2013 that were audited by the independent certifi ed public accounting fi rm, Mayer Hoffman McCann, PC, Boston, Massachusetts. A complete set of audited fi nancial statements is available upon request.

*Net of fi nancial assistance totaling $731,610 and $719,927 in 2014 and 2013 respectively

BFS Strives to Provide Treatment to All Who Need ItBoston Foundation for Sight (BFS) is a 501(c)(3) nonprofi t eye healthcare organization. Our Needham, Massachusetts, Center of Excellence includes a medical institute, a research center, a state-of-the-art manufacturing lab and a Patient and Family Support Center. As demonstrated by the income statement below, the majority of our income is generated from insurance and patient payments.

As a nonprofi t, BFS actively solicits gifts and grants to support and develop the foundation and fulfi ll its mission. We are committed to providing fi nancial assistance to patients so that their lives are no longer lost to constant eye pain or limited by poor visual function.

In 2014, BFS provided more than $730,000 in fi nancial assistance to patients in Needham and within the

domestic BostonSight® Provider Network. However, the aid required by our patients outstripped philanthropic gifts, which were lower than in other years. By deepening their commitment, donors will help BFS continue to provide PROSE treatment to all who need it.

$ 2,439,602

1,161,100 755,200 123,821

56,920

4,536,643

185,361 32,918

218,279

435,498

$ 5,190,420

$ 813,390 813,390

813,390

4,151,186 40,844

185,000

4,377,030

$ 5,190,420

PAGE 13

Current assets: Cash and cash equivalents $ 3,056,784 Accounts receivable — patients, net of reserve for doubtful accounts of $248,000 and $288,000 in 2014 and 2013, respectively 1,001,556 Accounts receivable — network clinics 535,750 Other receivables 67,238 Prepaid expenses 80,027 Total current assets 4,741,355

Other assets: Restricted cash 185,012 Deposits 32,918

Total other assets 217,930

Property and equipment, net 291,878

Total assets $ 5,251,163

Liabilities and Net Assets

Current liabilities: Accounts payable and accrued expenses $ 1,012,616 Total current liabilities 1,012,616

Total liabilities 1,012,616

Net assets: Unrestricted net assets 4,029,799 Temporarily restricted net assets 23,748 Permanently restricted net assets 185,000 Total net assets 4,238,547

Total liabilities and net assets $ 5,251,163

2 0 1 4 B A L A N C E S H E E T December 31, 2014 2013

Assets

$1,000,000 and aboveBausch + Lomb

$250,000 - $999,999Lorne AbonyNehemias Gorin Foundation and Gorin Family EndowmentMichael and Myra McCoyThe Thomas Anthony Pappas Charitable FoundationThe Samuel Rapaporte, Jr. FoundationKate and Seymour Weingarten

$100,000 - $249,999Frank and Diana BerryHarry and Honey BirkenruthHenry and Diane BisgaierBlue Cross Blue Shield of Massachusetts FoundationThe Charles Evans FoundationBruce and Holly JohnstoneFlorence KoplowAvinash and Anuja LeleMarino Charitable FoundationMichael L. Nash and Carolyn DuffyRobert and Ruth RemisRobert and Beatrice SchaeberleMichael and Helen Schaffer FoundationThe Abraham Shapiro Charity FundEnid Starr, Esq.*Diane Tonna and George Tonna

$50,000 - $99,999Warren Alpert FoundationEvelyne BalboniTheodore W. and Evelyn G. Berenson Charitable FoundationIrena Bronstein and Eugene Bonte Charitable FoundationBresky FoundationComenitz Family FoundationLeRoy and Jane CrosbySumner and Esther FeldbergGerald Flaxer Charitable FoundationHoward GorinJohn and Olga GuttagAnn HintlianMax and Selma Kupferberg Family FoundationPaul T. LaRoccaMichael and Donna MoskowLarry and Audrey PlotkinHoward Stoner and Dr. Carol StonerAlan and Ann StrassmanPaul Szczygiel

$25,000 and aboveBruce and Holly JohnstoneMichael and Myra McCoyKate and Seymour Weingarten

$10,000 - $24,999AnonymousThe Barbara Epstein Foundation Frank and Diana BerryHarry and Honey BirkenruthHenry and Diane BisgaierIrena Bronstein and Eugene Bonte Charitable FoundationCognex CorporationFlorence Koplow Jane and Jerry Gnazzo

$5,000 - $9,999Edward and Nancy EskandarianAllan and Anne GreenbergJoseph MartiniMax & Selma Kupferberg Family FoundationMichael L. Nash and Carolyn DuffyMichael Raizman, MD and Debra RaizmanRonald Rock

$1,000 - $4,999Pamela J. AndersonThe Aronson FoundationLisa and Jay BerlinMarvin Berman and Ronna Finer-BermanRobert W. Best and Elizabeth WannerThomas and May ChinCharles ChurchillMerrill and Trudy CohenDennis and Jillian CorkumGertrude CrittendenLeRoy and Jane CrosbySandra DeFranciscoSumner and Esther FeldbergGary and Susan FentinEsther FreemanD. Catherine Fuchs, MDGerald Flaxer Charitable FoundationMaureen GillespieKaren L. GrossmanJudith GurewichRabbi Donniel and Adina HartmanElise C. Hauenstein and Norm AbramJon and Janice InwoodDouglas and Edythe JablonskyDeborah S. Jacobs, MD and Peter SacksJoseph B. and Esther L. Grossman Charitable FoundationMichael KaneDavid KatzJay T. KellyGary and Sandra KnaakAvinash and Anuja LeleShaun and Kathleen LevesqueMichael Link, MD and Vicki LinkPeter and Tina LockeRoger M. MarinoBarbara J. McNeil, MDAnna and Mark* Mergen, MDRichard MichaudHelaine MillerRoger and Roberta NealDonna NewmyerWilliam H. O’NeillRuth OrensteinCharles E. Rehn, MDRichard and Deborah SassonDelia Bowman SattinClifford Scott, OD and Mary Scott, ODPaul and Josephine SearsLinda and Richard SmithSpecialty Insurance Managers, Inc.Edward A. TanzmanAlice Trisdorfer, PhDMiriam E. Vincent, MDRobert K. WalterScott and Jacqueline WellmanJoseph and Susan Zienowicz

Visionary Circle of Hope donors

make gifts of $1,000 or more

within the calendar year. Their

generosity makes a tremendous

difference in the quality of life of

our patients and their families. The

important support from these

leadership donors helps us to

restore our patients’ sight, which in

turn helps them regain their lives.

Thank You to Our Valued Donors

Lifetime Giving

The following lists recognize donors whose gifts were received between January 1 through December 31, 2014.

Visionary Circle of Hope

PAGE 14

VisionaryCircle of Hope

*Deceased

PAGE 15

Mary Flair BoganRaymond BoghosAlan R. BolingEthan BolkerKathleen and James BondConstance BonnerKathleen K. BowenRobert K. BowerNancy BowersDonald and JoAnn BowmanSally Sparks BoydNora BoyleSusan BradyBill and Helen BragdonJack and Nancy BrennanPeter and Evelyn BrewsterRobert and Marie BrittFrancis and Linda BrockwayNorbert P. BrouchoudMaurice and Karen BrownJeanne BrunoKathryn R. BuckheitLeslie A. BurgKaren BurgessIan BurkePeter BurnessTimothy BurnettJoseph BurrisMs. Nancy Naylor BusbyJohn and Debbie ButzThe Cacela FamilyGerald CadranCherilyn Caga-AnanFaye CalhounBetty and Joe CaplanJoanne CaputoSharlene CarterSteven and Kathleen CaseMarvin and Edith CatlerThomas and Jean CatlinVeronica CavacoJohn and Ellen CavaiuoloAnthony J. CavannaLarry and Ann ChaitBrandy ChambersArthur and Carole ChenDiane CimillucaDorothy CirianiKaren CliftJoan Cody-WingoJeffrey CohenRichard CohenCarole and Dom ColanninoRichard and Julie ColonMolly ComptonLee ConnorsNancy CookSusan R. CostelloDonna and Doug CowanJohn and Robin CoyneCraigs Landscaping Inc.

Bob and Donna MetaforaChris MoyroudJohn MulderJoan E. MurphyLouis PulzettiThe Remis Trust FundWilliam RodgersRobert and Susan SeylerCharles and Eileen ShareMr. and Mrs. Robert StromCharles and Susan TateArnold WallensteinJoseph and Erika WannemacherJerome and Joan WeinsteinWilliam Wright, MD and Joanna WrightEileen and Craig Yarnell

Under $250 Anonymous (25)Ruth AbelmannLawrence M. and Linda M. AbramsonRao AddankiLamia AdjoutMartha AkagiVirginia C. AldenBarbara AmatoAmazonSmile FoundationSeymour AndrusRichard ApalakianSteven M. AppelWilliam and Andrea ArcuriMark and Suzanne AucoinNorman and Monique AveyRobert AwkwardZella AxelrodBonnie BaderJim and Patricia BaileyRoss BaldessariniDavid BaltisbergerJanet BarkerKenneth BarnesPaul and Joetta BarnettStephen BarryMichael BaxterDouglas W. Bell, MDMichael and Helen BellasKathleen BellewKaryn BensonIris BerentJoanne BergerDaniel BerlinJoan Feinberg BernsScott and Katherine BerrierAlexandra BerwickPaul C. BettingerAnn BixelRichard Blacher, MDEvelyn BlanchardJaxon BobbittLindsay Bock

$500 - $999 Anonymous (2)Todd BirkenruthCail Family FoundationJ. Stephen and Linda E. CollinsJean and John ConnersCressey Sports Performance LLCTimothy FazioRichard GrigalunasSherri HendricksBeverly and Philip JohnstonRonald J. and Kristine K. KannDonald Korb, OD and Joan Korb, ODJanice R. LaneNancy and Maurice Lazarus FundJohn MaischThe Max & Elizabeth Blume Silverstein FoundationMary McCuneDavid and Dora MiddletonEleanore MoranJerry MulderDavid and Patricia NestlerCarmen Paradis and Brian McGrathMichael E. and Marti PartridgeJohn and Sharon PooleWilliam PospisilBrent and Caroline StoneCarl Valvo and Mav PardeeDorothy WaldronSteven and Sharon WeberDaniel and Rosemary WywodaZeitz Foundation Trust

$250 - $499 Abul Abbas, MD and Ann Abbas, MDKimberly BerryCarroll and Raymond C. CharetteAngela ChurchillJohn F. Cogan, Jr.Mary and Deborah CormierAnna Cressey, OD and Eric CresseyThe David Gopen FoundationJoe and Maureen FazioJohn E. FitzgeraldPeter. W. FitzRandolph, MDBetty Lou GallardoC.R. GriggHeidi Joy HodgesHeidi Price DesignTheodore and Ruth-Arlene HoweCharles and Joan KillileaIlene Knopping and Cliff KolovsonSharon and Howard LevitanHonorable Stephen M. LimonMark MaciolekMargaret Mansfi eldMark Martini and FamilyP. Mark Martini

BostonSight Donors

Robert CraneJohn and Holly CratsleyRuth CurranCynthia Costa DavisEric D.Joanne DaytonTom and Valarie DeFeliceJohn DeludeRobert and Julie DempseyKenneth and Marcia DenbergWilliam and Deborah DennettJean A. DesmondNancy DeSouzaMary DiabLi Diao and Haixiang Zhu Carlos Diaz GonzalezAmy DibattistaAlbert and Elizabeth DibbinsSandra DickJennifer DicksonElinor DiIorioRenee DomeganRichard and Joan DonnellyMichael T. DorsettArthur, Janice and Lynn DrinkwaterJohn and Lisa DubczakKevin DuganWilliam and Lori DugasMary DunbrackLois and Bernie EdinbergPhyllis EllisPatti EnglertDan EshetRhea T. Eskew, Jr.Cliff EvansJames and Catherine FallonHenry and Kathleen FaulknerRoslyn FeldbergSarah FeldbergStephen Feldhoff and Margaret O’Meara FeldhoffJames R. FelicettiDeborah Fenn and Stephan SteiselDavid FentonVictor S. FerreiraJacquelin FiedlerJohn FinnLuke F. FinnLesley and Mark FinnRon and Kathy FisherJamie and Dennis FloydJulia FoxJanice FoyeJohn FranconereVincent Fratello, PhDJonathan FriedmanSanford and Elyse FriedmanLinda and Michael FriezeAnthony FucilloMary FurlongBetty GerathyJeffrey GersonEdward GibsonBob and Joan GillespieKaren GillespieSean GillespieArlene GilmanTamara GilmanKaren Ginsberg

Edward GinsburgNancy Glazer PearlJeffrey Gold, MDValerie GoldsteinSheryl GoodridgeAnna S. GreenGary and Patricia GreenDottie and Bob GrodbergAron GrossmanClarke and Betty GuilliamsSarah GunneryEvan HabermanSterling HaleVivian Lee HamiltonCathleen HardistyJames and Helen HarneyDanielle HartiganChristopher HawrylowAnita L. HayesRobert and Janice Hayfl ickJordana R. HellerDeborah HirschGloria HittLillian HoDavid HobsonJohn F. HoganMarida HollosBrad HonoroffJoan HoogasianEllen HopkinsKenneth and Beverly HornMichael HornShirley HoughtonLynne HouriganLynn HughesRose HurwitzBarry and Doris HymanJeannette IlesElaine InkerRuth IsaacsWanda JacksonChristine JantzenJeanne P. ValenteKlavs JensenOdell Johnston, Sr. and Carol JohnstonE. Ann and Brian Keith JonesJohn J. JoyBarbara JuellCarolyn, Alan and Meryl KKaren KalirisRobert KaneA.W. and Barbara KarchmerBarbara KarrRobert and Geraldine KastnerJoel D. KatzLeslie S. KaufmanPatrick KeatingMargaret KelleyCarol KentDorothea P. KerleNancy KimKen and Melinda KimballHoward King, MD and Phyllis KingSuzanne Cook KinsellaghAnne M. KiritsyJudith Geleerd KitzesAndrew KleinDaniel KleinmanGerard J. Klingman

Elaine KnowltonJoseph and Dorothy KosewiczJoan KrasnooMichael J. and Ilana KrausBruce and Ruth KuhnertS.M. “Terry” and Rosalie LaCorteDeborah Lang-SaviniSusan LanteriLinda LargeFred LawrenceDarrow LeboviciKeng Jen and Judith M. LeeJohn LescherAlan LeventhalWendy LeveyBarbara LevineMartin and Sandra LevyCindy LewisNancy and Paul LidardWalter I. LipsettKenneth LoveJessica A. LoveJack and Maria LynchJoan Sullivan and Larry LynchPatrick E. LynchBrenna MaguireKathleen MalloyPhillip and Donna MalyakLillian MamonAnne MarcusNancy and Jean-Pierre MarjolletDiane MarksVivian and Richard MarsonAndrea W. MartinMatthew and Margarethe MashikianDaniel Massarelli, MD and Sheila MassarelliMark and Catherine MathersPatricia MatthewsDaniel M. McDonald, Esq.James McDonnelPaul McDonoughRichard McGantyMary McGillivrayJoan McGuirkWilliam and Eleanor McGuirkCarol McHughMary McMahon-ChappelDavid A. McMullinRalph and Ina MelenSherry Widman and Richard MendelsonNancy MercadoTony MessecRichard and Joan MetcalfeCarol T. Meyer and FamilyKalvin and Jan MilanSarah MillarJoanne L. MillerAlison Moll and Fred BenjaminEva MongeonRichard and Roberta MoranTuuli MorrillSteven MoskowitzCraig MulvaneyDan and Debra MurrayJosephine NapoliScott NascimentoWilliam and Rita NeedelNancy Nelson

PAGE 16

Carlos SaFlorence SaccoHoward R. SacksGeorge SahasShahzad SaleemAndrew SalkWillem Maarten SamsomM. Santiago, Jr.Brenda Hernandez Santiago, MDTedd and Ella SaundersJudy SaxeJoseph F. ScancarellaCasey ScavoneRobin L. Scholefi eldSylvia ScholnickMari Hirsh and James SchreiberJoanne SearsMarvin SegalBeth and Michael SellmanJoseph SergiSandra ShapiroNeil ShernoffGene Sherron, PhDChristopher and Linda ShumateStephen ShustermanStephen SilkAlfred and Roslyn SilvermanMichelle SilviaKaren SimatDevra SimonMargaret SimonShobha and Kamlesh SinghPaul and Terri W. SkiverSpencer SleeperEllen R. SmithKent SmithQuinn SmithNeal and Sierra SniderMarc SnyderBenjamin and Thelma SobleDorothy SolomonLaurie SparksRosalind SpigelKaren SpikesStanhope Garage, Inc.Marjorie StanzlerJoe Michalak and Judy SteenMerrill SteinDorothy SteinbachDonald SteinbrecherHoward Stoner and Carol Stoner, MDMark F. Straffi nDavid and Lorna StrasslerAlan and Ann StrassmanAndrew StraussAnn StromingerPatricia and Dennis StrusaAnna R. SullivanJames and Ruth SullivanJoan P. SzczepkowskiNancy TepperJames and Carol Ann ThomasPatricia ThomasIrwin Thompson, MDWinston C. ThompsonHarry TilyDavid and Karen TingMyrna TitelbaumLouis and Barbara Tobasky

Carlos Neu, MD and Judith NeuGary NewmanPaula NobiliWillard H. NobleMerle A. NollMike NovackCheryl O’BrienMary O’ConnorCarol J. OdmanAlice O’DonoghueEli and Bonnie OkrantDaniel OmaraMiriam L. Ornstein, MDRobert and Marjorie OryKathy OwenEltha PalmerMairead PaoliEdward ParolinNeal PearlmutterBeverly Siegal Peiser and Richard PeiserKendell PenneyCari PepkinThomas and Sharon PeroskyAugusta PetroneFrancis PettengillSteven PiantoadosiJohn PicerneEllen Pichey, MDDavid PillemerTamela Hoover PinkFrank J. PirrottaWilliam and Sheila PocaroSusan PolivyCarmen PuopoloJason PuzniakLinda RacineRaymond and Geraldine RadzanowskiRichard RaiselisLyndsey M. RawsonOrlyn ReeseCintra ReeveLorraine ReganSusan ReganTeri PiattLinda ReichertMichael Reinhorn, MD and Stefanie ReinhornSherry ReisnerDavid and Chelsey RemingtonJames ReynoldsRichard ReynoldsAnita RiceRoberta RichardsElizabeth RiordanCharles RobbinsCesar RodriguezThomas and Mary RogersIlana RomanTereso Saucedo and Luz Rosales-LopezBeverly RosenKaren RosenPaula RosenSylvia RosenblattCynthia Rosenstein and Marty YespaPatricia and Leonard RosenthalJulie RossBarbara RostoskyJacqueline Royce, MDT. Michael and Angela C. Russo

Herbert TobinMolly TobinSharee K. TolbertRobert C. TommasinoJian Tong-ClarkJan TornickThomas TorontoDavid TorresWillard TraubSotirios Tsimikas, MD and Athena TsimikasRichard L. TuckNelson and Lynn TuckerSamantha TyeTed TyeSheri M. UlianoUMassMemorial Medical Center Care Coordination Dept.Eric and Laurie Van LoonJulie VanekMarcos VargasElizabeth Varley-HoranVictoria VasermanAngela VelozJean M. VnenchakJeanne and Jim WalkerThe Walsh FamilyJudith WarnementEllen WassarmanKenneth and Femi WassermanBrian WassersteinAnne WeatherwaxHerbert and Eleanore WeissIrwin WeissMonika WellensteinVictoria WhalenAnthony Whittemore, MDJohn WilkinsJames and Melissa WillisJohn and Sheila WilsonRichard and Frances WinnegAndrew WolffAndy WongRobert WoodburyLoreen Afua WutohJustin WynerMarcia YanofskyJudy Dunn and Stephanie YonowitzClement Zielinski

G I F T S I N K I N DBausch + Lomb

M A T C H I N G G I F T SBank of AmericaBNY MellonCargillChevron CorporationCNA FoundationJohnson & JohnsonLiberty Mutual FoundationQualcomm

Every effort has been made to ensure the accuracy of our donor listings. If there is a misspelling, omission or improper listing, please accept our sincere apologies and call 781-726-7512 so that we may correct our records.

464 Hillside Avenue, Suite 205Needham, MA 02494781-726-7337 www.bostonsight.org

Board of DirectorsGary A. Knaak ChairmanEugene A. Bonte, MBA President and CEOPamela J. AndersonMark EaleyGary S. Fentin, Esq.Andrew Hirsch, MBABeverly R. JohnstonMichael Kane, MBABarbara Joyce McNeil, MD, PhDMichael B. Raizman, MDClifford Scott, OD, MPHKate Weingarten, MBA, CFA, MPA

Boston Foundation for Sight

Medical StaffDeborah S. Jacobs, MD Medical DirectorKaren G. Carrasquillo, OD, PhD, FAAO Director, Clinical CareRutvi Doshi, OD, FAAOAlan Kwok, OD, FAAOAmy Paminder, MDChirag Patel, OD, FAAOCrystal Remington, OD, FAAO

Senior Staff Eugene A. Bonte, MBA President and CEOCarmen R. Addario, MPAH Chief Operating Offi cerManoel Carvalho Lab ManagerSteve Corlett Director of Lab OperationsMelinda Kimball Human Resources and Payroll ManagerIlene Knopping Director of the BostonSight® NetworkOlga Tomashevskaya Director of EngineeringSara Yost, MBA Director of Finance and Administration

StaffPedro AraujoAlana BakerArtur BarbosaAshley BritoSusan CarlyleLynn CarterSamantha CohenRita DeFlaminisYurly FershterKyle FonsecaGillian FontanaElizabeth GibsonDaniel GosselinYudit GuzmanMelissa HatchSheila KellyBill KingNancy LemistDavid LoomisPernell McDanielMarianne O’SullivanIsabell OfgantHenryka PaczuskaKevin RenaudDarlene RiordanRobert SmithLoren SteadTara StepanianHeidi Wolfe

Design: Heidi Price DesignEditorial Services: Laura DuffyPhotography: Tony RinaldoKimberly McKinzie (page 7)