VirusGiant cells producedFetal or neonatal important diseaseDiagnostic techniqueCommon Antiviral therapy

HSV-1YesNoCultureAcyclovir

HSV-2YesYesCultureAcyclovir

VZVYesNoCultureAcyclovir

CMVYesYesCultureGanciclovir

EBVNoNoHeterophilNon

HHV-8

HSV1 clinical symptoms

NoNoDNA probesAlpha interferon

CLINICAL FEATURES OF HERPES VIRUSES:diseasesymptoms

gingivostomatitisFever , irritability, vesicular lesions in mouthMainly occur in children. primary infection is severe then reccurrence.

Herpes labialisFever blisters or cold sores. crops of vesicle at muccocutaneous junction of lips and nose

keratoconjunctivitisCorneal ulcers and lesions of conjuctival epithelium. Recurrence may lead to blindness

encephalitisNecrotic lesion on one temporal lobe ,Fever ,headache, vomiting ,seizures altered mental status

Herpes whitlowPustular lesion on skin fingers and hands

Herpes gladiatorumCommon in wrestles.Vesicular lesion on head neck and trunk.

HSV 2Disease Symptoms

Genital herpesPainful vesicular lesions on male and female genitals and anal area.Primary infection fever and inguinal adenopathyAsymptomatic in prostate and cervix

Neonatal herpesOriginates from contact with vesicular lesions of birth canal.Disseminated lesions occur: severe= encephalitismild= local lesions on skin eye mouth.