It's one thing to recognize a type of tissue from a carefully drawn diagram and quite another to identify a tissue from an actual sample. The Virtual Histology Microscope is the next best thing to examining actual samples under a microscope. You can control the focus, lighting, and magnification but more importantly, you can move each slide to search for something specific. Study the diagram below, then go to “Getting Started”.

Open the Virtual Histology Microscope at https://goo.gl/DD5eNUfrom the Open Science Laboratory

Getting Started - How to use the Virtual Microscope

Open the Virtual Histology Microscope at https://goo.gl/DD5eNU

1. Select the Category “Basic”.2. Select the slide for Specimen 1.3. Set the Magnification to “x2”.4. The specimens is blurry so we need to adjust the focus.5. Move the slide so that the + is on something interesting.6. Increase the magnification to x4, then x10, then x20, and then x40. Adjust the focus and lighting.7. Answer the questions for Specimen 1 on the next page.

Magnification

Take a Picture

Focus Lock Tool

Adjust Light

Adjust Focus

Coordinates of Crosshairs

move to search slide

Select Category

Select Specimen

Specimen Description

Virtual Histology Lab

Hints:

• It’s easier to search a slide at lower magnification and then switch to a higher power to see more detail.

• You can type in the crosshair coordinates to find an exact location on a slide.

Your Name: ____________________________

Specimen 1 - Buccal squamesCategory: BasicSlide: #1

Search the slide until you find a group of cells that look similar to those in the picture.

1. What magnification was used in the picture? ______________2. What type of cells are these? __________ A. Striated Muscle B. Motor Neurons C. Adipose Connective Tissue Cells D. Squamous Epithelial

3. Where in the body are they found? ________________________________________

Specimen 1

Specimen 2 - Normal Blood SmearCategory: BasicSlide: #2

Search the slide until you find cells that look similar to those in the picture.

4. What magnification was used in the picture? ______________5. Which structures are Red Blood Cell? ________ (A B C)6. Which structures are White Blood Cell? ________ (A B C)7. Which structures are Platelet? ________ (A B C)8. What type of tissue is this? Epithelial / Muscle / Nervous / Connective

Specimen 3 - Cardiac MuscleCategory: BasicSlide: #28

Search the slide until you find cells that look similar to those in the picture.

9. What magnification was used in the picture? ______________10. What type of tissue is this? Epithelial / Muscle / Nervous / Connective11. Where in the body is it found? ________________

12. Increase the magnification to x40. Can you actually see striations? _______

Specimen 3

Specimen 2

C

BA

Questions: page 2

Specimen 4 - Striated MuscleCategory: BasicSlide: #29

Search the slide until you find a group of cells that look similar to those in the picture. Note the crosshair coordinates (you can type these in).

13. What magnification was used in the picture? ______________14. What type of cells are these? __________15. Which arrow points to Muscle Fibers? ______ (A B C)16. Which arrow points to Nuclei? ______ (A B C)17. Which arrow points to Striations? ______ (A B C)18. Where in the body are they found? _________________________________

Specimen 5 - Temporal LobeCategory: Central Nervous SystemSlide: #13

Search the slide until you find cells that look similar to those in the picture. These are Astrocytes (glial cells); they are similar to neurons.

19. What type of tissue is this? Epithelial / Muscle / Nervous / Connective20. Where in the body is this found? ___________________

Specimen 6 - IleumCategory: GutSlide: #15

Search the slide until you find cells that look similar to those in the picture (or go directly to the image coordinates).

21. What magnification was used in the picture? ______________22. What part of the body is this from? ________________23. Which arrow points to the villi? ______ (A B C)24. Which arrow points to Epithelial Cells? ______ (A B C)25. What type of Epithelial cells are they? ______ A. Simple Squamous B. Simple Cuboidal C. Simple Columnar

Coordinates:X = 1452 Y= 4046

Specimen 4

C

B A

Specimen 5

Coordinates:X = 2666 Y= 15070

Specimen 6

BA

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Explore on Your Own

Now it’s your turn to explore the remaining samples and pick a few that you can identify. Fill in the chart below and draw a diagram of what you see.

Category: _________________ Specimen: ______Magnification: ______What type of tissue: _________________Where in the body is it found? ____________________________________________

Category: _________________ Specimen: ______Magnification: ______What type of tissue: _________________Where in the body is it found? ____________________________________________

Category: _________________ Specimen: ______Magnification: ______What type of tissue: _________________Where in the body is it found? ____________________________________________

Category: _________________ Specimen: ______Magnification: ______What type of tissue: _________________Where in the body is it found? ____________________________________________

Draw a diagram(or insert a picture if filling out digitally)

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