Vicki& Joe

Bioinformatics DNA -> RNA-> Protein Codons

64 Different Codons Replication -> Transcription

-> Translation Sequence Alignment

DNA: AGTCTCGTTACTTCTTCAAAT RNA: AGUCUCGUUACUUCUUCAAAU Codons: AGU CUC GUU ACU UCU UCA AAU Protein: SLVTFLN AGU - serine - S- ser CUG - leucine - L - leu GUU - valine - V - val

ACU - threonine - T - thr UCU - phenylalanine - F - phe

UCA - leucine - L - leu AAU - asparagine - N - asn

Simple comparison between sequencesMatchesMutations

Different Letters In Both RowsInsertion

Space In Top RowDeletion

Space In Bottom Row

Input: DNA Sequence “1921 attttataga aaaatctctt”

Cleans The String attttatagaaaaatctctt

Searches:TTA, CTA, or TCA (Start Codons)CAT (End Codon)Checks Size (Pseudogene, Potential Gene)

Output:Potenial Gene String

DNA-RNA-ProteinNobelprize.org

Genetic Home Referenceghr.nlm.nih.gov

A Science Primerncbi.nlm.nih.gov

Computer science and bioinformaticsCommunications of the ACM

Volume 48 ,  Issue 3  (March 2005)

1. How many chemical bases are in a codon?

2. What is one starting codon and the end codon?

3. How Many Different Codons are there?

4. How many amino acids are there?