vestibular system - uzhkiper/vestibular.pdfvestibular system a central role in the maintenance of...
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Systems NeuroscienceOct. 22, 2019
Vestibular system
Daniel C. Kiper
http: www.ini.unizh.ch/~kiper/system_neurosci.html
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VESTIBULAR SYSTEMA central role in the maintenance of equilibrium
and gaze stability.
The vestibular system, by means of its receptors for the perception of linear and angular acceleration, plays a central role in orientation.
Designed to answer two basic questions:
Which way is up?In which direction am I moving?
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VESTIBULAR SYSTEM
Very elusive to test
Five peripheral “receptors” (three
semicircular canals, utricule, saccule)
Nerve (sub-divisions)
Central connections
Cortical area
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The Semicircular Canals
• posterior canal shares plane with contralateral anterior canal.
• horizontal canals share plane.
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Vestibular Hair Cells
• Type I
(aka inner)
• Type II
(aka outer)
With Kinocilium
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Responses of the Cristae
• All kinocilia are oriented in the same direction
• Crista in each pair of canals respond inversely to each other
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The Otolithic Organs
Saccule: roughly
vertical orientation,
responds to acceleration components within saggital plane
Utricle: horizontal (+ 30 deg.) orientation9
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Excitation Patterns in the Utricle
STRIOLA
Posterior
Anterior
Medial
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The otoliths register linear acceleration
and static tilt
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Vestibular system
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Vestibular System
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Vestibular Nuclei (VN)
Vestibular signals originating in the two labyrinths first interact with signals from other sensory systems in the VN.
Only one fraction of the neurons in the VN receive direct vestibular input, and most neurons receive afferent input from other sensory systems (visual or proprioceptive) or regions of the CNS (cerebellum, reticular formation, spinal cord and contralateral VN).
Consequently the output of neurons from the VN reflect the interaction of many systems.
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Vestibular Cortex
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Schematic representation of the temporo-peri-Sylvian vestibular cortex (TPSVC). The vestibular
sites located at the lateral aspect of the right or left hemispheres are projected on a lateral view
of the right hemisphere normalized in the proportional stereotactic grid system of Talairach and
Tournoux. BA = Brodmann area; CA-CP = anterior commissure-posterior commissure plane; VCA
= vertical plane through CA; VCP = vertical plane through CP; SF = Sylvian fissure; STS =
superior temporal sulcus; 1stTG = first (superior) temporal gyrus; 2dTG = second (mid) temporal
gyrus. (red dots) Yaw plane illusions; (pink dots) pitch plane illusions; (blue dots) roll plane
illusions; (green dots) translations; (black dots) indefinable sensations of body motion.
Vestibular Cortex
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Vestibulo-Ocular Reflex (VOR)
To hold images of the seen world steady on the retina
during brief head rotations
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Dizziness – Vertigo - Disequilibrium
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