ventricular assessment of size,shape and function

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    Element 52.00Element 52.00

    PellerinPellerin

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    The 20th Echo in Context Video Teleconference

    The pulse and the beat. ECG and Echo

    Saturday, 26th February 2005

    The 20th Echo in Context Video Teleconference

    The pulse and the beat. ECG and Echo

    Saturday, 26th February 2005

    Ventricular Assessment ofSize, Shape, and Function in

    ECH Disorders

    Ventricular Assessment ofSize, Shape, and Function in

    ECH Disorders

    Dr. Denis Pellerin MD, PhDDr. Denis Pellerin MD, PhD

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    g Ventricular assessment of size, shape, and function has

    important

    prognosis and therapeutic implications

    g Ventricular volume predicts mortality better than ejection

    fraction

    Simpsons rule in 2D (biplane), in 3D (LVESD)

    Ventricular mass

    g Ventricular geometry is a surrogate for myocardial fibers

    orientation

    Adaptive mechanism to maximize pump efficiency(remodeling)

    Changes in radial, longitudinal and circumferential motion

    Ratio of WT to cavity dimension, Sphericity index

    g Ventricular assessment of size, shape, and function has

    important

    prognosis and therapeutic implications

    g Ventricular volume predicts mortality better than ejection

    fraction

    Simpsons rule in 2D (biplane), in 3D (LVESD)

    Ventricular mass

    g Ventricular geometry is a surrogate for myocardial fibers

    orientation

    Adaptive mechanism to maximize pump efficiency(remodeling)

    Changes in radial, longitudinal and circumferential motion

    Ratio of WT to cavity dimension, Sphericity index

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    Aurigemma GP et al 2002Aurigemma GP et al 2002

    NormalNormal

    Concentric

    Remodeling

    (Hypertension)

    Concentric

    Remodeling

    (Hypertension)

    Concentric

    Hypertrophy

    (Hypertension/

    Aortic)

    Concentric

    Hypertrophy

    (Hypertension/

    Aortic)Hypertrophic

    Cardiomyopathy

    Hypertrophic

    Cardiomyopathy

    Eccentric

    Hypertrophy

    (Aortic/

    Mitral

    Regurgitation)

    Eccentric

    Hypertrophy

    (Aortic/

    Mitral

    Regurgitation)Dilated

    Cardiomyopathy

    Dilated

    Cardiomyopathy

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    Assessment of Global LV Systolic FunctionAssessment of Global LV Systolic Function

    RWMA, post op, LBBBRWMA, post op, LBBB

    NoNo YesYes

    M-mode measurementsTeicholz methodM-mode measurementsTeicholz methodg

    Visual estimation of LVEFg Biplane Simpsons method

    g Mitral annular velocity

    g RWMSI

    g dP/dt

    g

    Visual estimation of LVEFg Biplane Simpsons method

    g Mitral annular velocity

    g RWMSI

    g dP/dt

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    LV Volumes and Systolic FunctionLV Volumes and Systolic FunctionVENTRICULAR VOLUMESVENTRICULAR VOLUMES

    g

    Intra observer variability: 4 a 6%

    g Inter observer variability:

    g

    Intra observer variability: 4 a 6%

    g Inter observer variability:

    8.5% EDV8.5% EDV 16.5% ESV16.5% ESV

    g A variation ofg A variation of 15% for EDV

    25% for ESV

    10& for LVEF

    15% for EDV

    25% for ESV

    10& for LVEF

    is required before concluding on a

    significant change.

    is required before concluding on a

    significant change.

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    Mitral Annular VelocityMitral Annular Velocity

    Gulati VK et al. Am J Cardiol 1996; 77:979-984Gulati VK et al. Am J Cardiol 1996; 77:979-984

    g Velocity assessment is not dependent on endocardial definition

    Conventional echo 77%, DTI measurements 100% (Alam JASE 2000)

    g MAV > 5.4 cm/s was 88% sensitive and 97% specific for LVEF > 50%

    g Limitations: prosthetic MV or annulus, mitral annular calcifications

    g Velocity assessment is not dependent on endocardial definition

    Conventional echo 77%, DTI measurements 100% (Alam JASE 2000)g MAV > 5.4 cm/s was 88% sensitive and 97% specific for LVEF > 50%

    g Limitations: prosthetic MV or annulus, mitral annular calcifications

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    Atrial FibrillationAtrial Fibrillation

    Perrenoud JJ 1989Perrenoud JJ 1989

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    Assessment of Regional LV SystolicFunction

    Assessment of Regional LV SystolicFunction

    g SEMI QUANTITATIVE ANALYSISConventional 2D echo

    LV cavity contrast opacification in 2D

    g QUANTITATIVE ANALYSIS

    Myocardial velocity and deformation Imaging

    Color kinesis + LVO

    3D echo (+ LVO)

    g At rest and during stress

    g SEMI QUANTITATIVE ANALYSISConventional 2D echo

    LV cavity contrast opacification in 2D

    g QUANTITATIVE ANALYSIS

    Myocardial velocity and deformation Imaging

    Color kinesis + LVO

    3D echo (+ LVO)

    g At rest and during stress

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    Cineloop of a patient with CHF and narrow QRS

    complexes

    Cineloop of a patient with CHF and narrow QRS

    complexes

    Cineloop of a patient with CHF and LBBBCineloop of a patient with CHF and LBBB

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    ??

    Delay between RV and LV activation 85 msDelay between RV and LV activation 85 ms

    Grines CL et al. Circulation 1989Grines CL et al. Circulation 1989

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    CONCLUSIONCONCLUSIONg Ventricular assessment of size, shape and

    function has important prognosis andtherapeutic implications

    g Global and regional LV function: select your

    parameter (when poor endocardial definition or

    abnormal septal Motion)

    g RWM analysis requires training

    g Conventional analysis/Quantitative analysis

    g Ventricular assessment of size, shape and

    function has important prognosis andtherapeutic implications

    g Global and regional LV function: select your

    parameter (when poor endocardial definition or

    abnormal septal Motion)

    g RWM analysis requires training

    g Conventional analysis/Quantitative analysis

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