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©2015 Trinity Health. All Rights Reserved. 1 Value of Pharmacy in the Emergency Department Jessica Ellis, PharmD Christopher Shaw, PharmD, BCPS St. Mary Medical Center Langhorne, PA

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©2015 Trinity Health. All Rights Reserved. 1

Value of Pharmacy in the Emergency Department

Jessica Ellis, PharmD Christopher Shaw, PharmD, BCPS

St. Mary Medical Center Langhorne, PA

©2015 Trinity Health. All Rights Reserved. 2

• Personal or financial relationships with commercial interests

• The authors of this presentation have no disclosures concerning possible personal or financial relationships with commercial entities that may have a direct or indirect interest in the subject matter of this presentation.

Disclosure

©2015 Trinity Health. All Rights Reserved. 3

• Explain how pharmacists prevent medication errors in the ED

• Illustrate how pharmacy technicians in the ED impact the medication reconciliation process

• Describe a comprehensive ED-based pharmacy program for optimizing quality of care, patient safety and financial benefits to healthcare organizations

Objectives

©2015 Trinity Health. All Rights Reserved. 4

Pharmacists as a Safety Measure in the Emergency Department

Christopher Shaw, PharmD, BCPS Clinical Pharmacy Specialist

Emergency Medicine St. Mary Medical Center

Langhorne, PA

©2015 Trinity Health. All Rights Reserved. 5

• Have you ever flown on a plane?

• Have you been on 3 or more flights?

• Have you ever been in a plane crash?

Audience Participation

©2015 Trinity Health. All Rights Reserved. 6

• What is the rate of an “Error-Free” Flight

• Why don’t planes fall out of the sky more often?

• How can we apply what is commonplace in the airline industry to healthcare, and the ED in particular?

Commercial Aviation

©2015 Trinity Health. All Rights Reserved. 7

• Unpredictable

• Chaotic

• Variable

Emergency Department

©2015 Trinity Health. All Rights Reserved. 8

• Goal- High quality, efficient, safe care to diverse population

• Reality?

• 129.8 million visits (2010 data)

• 75% have at least 1 medication administered/prescribed

- 210 million medication encounters annually

• 3.8 million preventable events annually (IOM)

- 77% of ADEs occur between ordering and administration phase

Emergency Department

Am J Med Qual. 2008; 23 (3): 231-233.

©2015 Trinity Health. All Rights Reserved. 9

• Stressful environment

• Crowding/Boarded patients

• Fewer EDs nationally

• Rapid clinical decision making

• Verbal orders

• Incomplete medical records

• Multi-tasking with frequent interruptions/distractions

• Patient information gaps

A Perfect Storm- Safety in the ED

©2015 Trinity Health. All Rights Reserved. 10

• Exception to the medication use process as followed in most areas

• Point-of-care

• Ordering

• Dispensing

• Administration

• Verbal orders

• Urgent, high-stress situations

Medication Use Process in the ED

Am J Med Qual. 2008; 23 (3): 231-233.

©2015 Trinity Health. All Rights Reserved. 11

• Established safety mechanisms normally NOT available in the ED:

• Prospective Rx Review

• Rx oversight of verbal orders

• Pharmacy preparation of medications

• Pharmacist involvement in clinical decision making

ED Medication Errors

Hobgood CD. Just the Pearls: Patient Safety, What You Need To Know For Compliance.

In: American College of Emergency Physicians Scientific Conference October 15-18,

2011; San Francisco, CA.

©2015 Trinity Health. All Rights Reserved. 12

• Proven to improve process measures:

• Time to cardiac catheterization lab

• Antibiotic timing in PNA

• Pain management

• Cost savings/avoidance benefit to ED

• Majority is avoiding costs associated with ADEs

Emergency Medicine Pharmacist

©2015 Trinity Health. All Rights Reserved. 13

• First reported in 1970s

• Initially inventory control and satellite development

• 1976- strictly clinical roles reported

• Growth- professional advocacy

• Cost avoidance, increased safety

• 10.5% of Level I Trauma Centers

• 2.7% without Level I Designation

Emergency Medicine Pharmacist

AJHP. 2009; 66 (15): 576-579.

©2015 Trinity Health. All Rights Reserved. 14

• Respond to traumas, resuscitations, critical patients

• Clinical decision making/ consultation with physicians or other prescribers

• Healthcare provider education

• Patient consultation/education

Emergency Medicine Pharmacist

The Emergency Department Pharmacist as a Safety Measure in Emergency Medicine. October 2004.

Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/quality-

patient-safety/patient-safety-resources/resources/pips/fairbanks.html.

©2015 Trinity Health. All Rights Reserved. 15

• Error reduction: individual system

• Systems approach creates layers to reduce chance of errors reaching the patient

• Make it difficult for error to occur

• “Absorb” errors that do reach patient

• By being available in the ED, the EM pharmacist’s ability to be involved in tailoring decisions to specific patients is increased

EM Pharmacist as a System-Level Safety Intervention

The Emergency Department Pharmacist as a Safety Measure in Emergency Medicine. October 2004.

Agency for Healthcare Research and Quality, Rockville, MD. http://www.ahrq.gov/professionals/quality-

patient-safety/patient-safety-resources/resources/pips/fairbanks.html.

©2015 Trinity Health. All Rights Reserved. 16

• Screening for and reporting ADEs

• Preventing errors from re-occurring

• FMEAs

• RCAs

• Process improvements

• Proactive and continuous monitoring of medication practices

EM Pharmacist as a System-Level Safety Intervention

J Pharm Pract. 2011; 24 (2): 135-145.

AJHP. 2011; 68 (23): e81-95.

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• 4 Academic EDs

• Primary outcome- medication errors recovered by pharmacist

• Near miss, potential ADE

• Mitigated ADE

• Ameliorated ADE

• Clinical outcomes not evaluated

Medication Errors Recovered by ED Pharmacists

Ann Emerg Med. 2010; 55 (6): 513-521.

©2015 Trinity Health. All Rights Reserved. 18

• 226 observation sessions; 787 hours

• 17,320 medications reviewed by pharmacist

• 6,471 patients impacted

• 504 recovered medication errors identified

• 7.8 per 100 patients

• 2.9 per 100 medications ordered/administered

Medication Errors Recovered by ED Pharmacists

Ann Emerg Med. 2010; 55 (6): 513-521.

©2015 Trinity Health. All Rights Reserved. 19

• 90.3% errors intercepted were potential ADEs • 3.9% mitigated ADEs • 0.2% ameliorated ADEs • Severity

• Serious- 47.8% • Significant- 36.2%

• Medication Classes • Antimicrobial agents- 32.1% • CNS agents- 16.2% • Anticoagulant and thrombolytic agents- 14.1%

Medication Errors Recovered by ED Pharmacists

Ann Emerg Med. 2010; 55 (6): 513-521.

©2015 Trinity Health. All Rights Reserved. 20

• Medication Classes

• Antimicrobial agents- 32.1%

• CNS agents- 16.2%

• Anticoagulant and thrombolytic agents- 14.1%

• Error types

• Dosing errors

• Drug omission

• Wrong frequency

Medication Errors Recovered by ED Pharmacists

Ann Emerg Med. 2010; 55 (6): 513-521.

©2015 Trinity Health. All Rights Reserved. 21

• 4 Medical Centers • Academic and Community

• Medication error interceptions recorded for 250 hours of cumulative time at each site

• Items recorded included: • Activities that led to interception of error

• Types of orders

• Phase of medication use process

• Type of error

Pharmacist Activities Resulting in Medication Error Interception in the ED

Ann Emerg Med. 2012; 59 (5): 369-373.

©2015 Trinity Health. All Rights Reserved. 22

• 16,446 patients presented to ED

• 364 confirmed medication error interceptions

• Activities that led to interception:

• Consultation- 51.4%

• Order review- 34.9%

• Other- 13.7%

Pharmacist Activities Resulting in Medication Error Interception in the ED

Ann Emerg Med. 2012; 59 (5): 369-373.

©2015 Trinity Health. All Rights Reserved. 23

Pharmacist Activities Resulting in Medication Error Interception in the ED • Types of orders:

• Written/computerized- 54.4%

• Verbal- 32.7%

• Other- 12.9%

• Prescribing phase- 82.4%

• Wrong dose- 44.2%

• Severity:

• Minor- 9.3%

• Significant- 65.4%

• Serious- 22.8%

• Life-threatening- 2.5%

Ann Emerg Med. 2012; 59 (5): 369-373.

©2015 Trinity Health. All Rights Reserved. 24

• UKCMC Case Study

• Interventions in the ED

• 353 in 6 months

• Median Cost of Medication Error: $268

• Cost Avoidance= $94,604

• Annuitized= $189,208

• If error in ED, 3x likelihood of admission

Cost of Medication Errors in the ED

Bowman B. The Cost of Medication Errors in the Emergency Department. UKCMC.

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• Detroit Receiving Hospital

• $436,150 avoidance from prevention of medication errors by pharmacist

• 4 month period

Cost of Medication Errors in the ED

AJHP. 2007; 64: 63-68.

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• EM Pharmacist position is recommended by ASHP and the Institute of Medicine

• Value of physical presence of pharmacists in the ED repeatedly reported in patient-safety literature

• Significant cost avoidance

• EM Pharmacist role is highly valued by Physicians and RNs; and improves patient safety and quality of care

Take Home Points

Emerg Med J. 2007; 24: 716-719. AJHP. 2009; 66 (15): 576-579.

AJHP. 2010; 67: 1595-1597.

©2015 Trinity Health. All Rights Reserved. 27

Pharmacy Technician-Led Medication Histories in the Emergency Department

Christopher Shaw, PharmD, BCPS Clinical Pharmacy Specialist

Emergency Medicine St. Mary Medical Center

Langhorne, PA

©2015 Trinity Health. All Rights Reserved. 28

• “Process of comparing the medications a patient is taking (and should be taking) with newly ordered medications”

• Resolve discrepancies or potential problems

• Prevent unintentional changes to medication at transitions in care

• National Patient Safety Goal 03.06.01

Medication Reconciliation

Hospital: 2015 National Patient Safety Goals. November 2015. Oakbrook Terrace,

Illinois. http://www.jointcommission.org/assets/1/6/2016_NPSG_HAP_ER.pdf

©2015 Trinity Health. All Rights Reserved. 29

• Medication errors are most common health-system error

• Occur in 70% of patients at hospital admission or discharge

• One-third have the potential to cause patient harm

• ADEs result in increases in direct costs and length of stay (LOS) per event • $3,420 ($2,852-$8,116) and 3.15 (2.77-5.54) days per ADE

Adverse Drug Events

JAMA. 1997; 277 (4): 307-311.

JAMA. 1997; 277 (4): 301-306.

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• MHTs introduced in April 2013

• 24/7 MHT coverage beginning July 2013

• Goal- Complete Best Possible Medication History (BPMH) for 75% of patients admitted through Emergency Department

• All medication and allergy information entered into our electronic medical record (EMR) for provider review and action

Medication History Technicians

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• Multiple sources of information

• Allergies and reactions

• Preferred outpatient pharmacy

• Medications

Best Possible Medication History

New or recently changed/stopped medications Vitamins, supplements, herbal medications

Eye drops, ear drops, nasal sprays Anything taken once a week or once a month

Topical patches, creams, ointments Over-the-counter medications

Inhalers/nebulizers Medication samples

Insulin or other injectable medications Medication pumps- internal or external

©2015 Trinity Health. All Rights Reserved. 32

0

500

1000

1500

2000

2500M

ay-1

3

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g-1

3

Nov

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Feb-

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May

-14

Au

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May

-15

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Patients Interviewed

Patients Admitted

Medication Histories Completed

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70%

75%

80%

85%

90%

95%

100%

2013

2014

2015

Medication Reconciliation

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• Comprehensive training and mentoring program

• Full-time and pool staff for 24/7 coverage

• “Right” MHT colleagues key to success of program

• Patient interaction/customer service experience

• Self-motivated

• Can adjust to varied workflow (no “typical” day)

• Helps “set the stage” for discharge medication reconciliation at point of admission

Medication History Program Highlights

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• Improved allergy and reaction documentation

• Combined Physician/RN/Pharmacy time reduced

• Increase patient interaction with pharmacy

• Implementation of Pharmacy Practice Model Initiative

• Repeat ED visits/admissions that are partially or wholly a result of medication therapy can be reduced (theoretical)

Additional Benefits

©2015 Trinity Health. All Rights Reserved. 36

• “Now that we have been working with the MHTs, I wouldn’t want to go back to the old system”

• “I was skeptical at first, but MHTs have more than proven they can benefit the patient, and the system as a whole”

• “MHTs have helped me make diagnoses with their histories on numerous occasions”

Provider Perspective

©2015 Trinity Health. All Rights Reserved. 37

• MHT Program provides a vital service to our patients

• Formal medication history program is the first step in the development of a comprehensive medication reconciliation program

• NPSG 03.06.01

• MHT program provides additional benefits to system outside of stated purpose

Conclusion

©2015 Trinity Health. All Rights Reserved. 38

Value of Pharmacy in the Emergency Department

Jessica Ellis, PharmD Christopher Shaw, PharmD, BCPS

St. Mary Medical Center Langhorne, PA