us pricing pressure steeper than expected

27
ICICI Securities Ltd. | Retail Equity Research May 18, 2017 Monthly Update US pricing pressure steeper than expected The Q4 numbers released by Glenmark Pharma and Dr Reddy’s have once again showcased continuing (and perhaps worsening) pricing pressure in the US base business. Both the managements indicated high single digit to low double digit price erosion in the US in the backdrop of client consolidation and intense competition, mainly in the oral segment. In a major development, the government has, on record, made its intention to mandate doctors to write generic names of medicines on the prescription. This move is intended to bring down drug prices and expand access to affordable health solutions. The Medical Council of India has warned doctors of action if they fail to adhere to its guideline on prescribing drugs in generic names. The Medical Council of India's (MCI's) directive comes after Prime Minister Narendra Modi spoke of putting in place a legal framework to ensure doctors prescribed low cost generic medicines to patients. On the M&A front, Jubilant Life has acquired radio-pharmacy business of Triad Isotopes in the US. Triad recorded revenues in excess of US$225 million in CY16 with positive EBITDA and operates the second largest radio- pharmacy network in the US with more than 50 pharmacies. On the US regulatory front, Biocon’s Bangalore plant has received eight USFDA observations, Lupin’s Aurangabad and Goa plants received three and eight observations, respectively, while Dr Reddy’s Hyderabad (Bachupally) plant 3 received 11 observations. Aurobindo’s Unit 3 plant also received six observations. On the innovation front, the USFDA has cleared Glenmark’s investigational new drug (IND) application to initiate a Phase 1 study of GBR 1342 (oncology). It has also received IND approval for its proposed biosimilar GBR310 (respiratory). Finally, the Indian pharmaceutical market (IPM) grew 8.3% YoY to | 9474 crore for April. IPM growth was mainly driven by volumes – 3.4%, new product launches – 3.2% and price hikes- 1.4%. On a MAT basis, IPM growth was at 10.5% YoY to | 111859 crore. No respite on US pricing front; subdued start to Q4 earnings Almost all players with US franchisee from the I-direct universe are facing intense competition in existing products and client consolidation in the US, leading to price erosion to high single digit to low double digit. Increased USFDA scrutiny and frequencies of inspection/re-inspection is also somewhat delaying key approvals. Apart from this, strengthening of the rupee vis-à-vis the US dollar is also likely to weigh in the near term. Similarly, other issues/uncertainty in the US like pricing probe by the Department of Justice (DoJ), adapting to the bidding process and imposition of border tax on imported drugs are other near term overhangs. Front loading of investments, although useful for long term growth strategy, is also likely to impact near term profitability. For the time being, attractive valuations and decent growth expectations for FY18, FY19 are likely to be on the backburner due to these apprehensions. In the long run, however, we expect the earnings momentum to pick up on the back of incremental product launches largely on speciality, biosimilar and injectables front in the US besides normalising of Indian formulations growth. Health Check Sector View Neutral Index Performance as on May 17, 2017 Return (%) 1M 3M YTD 1Y CNX 500 4 10 20 27 Nifty 4 8 16 21 NSE Pharma -2 -4 0 -9 Return (%) Stocks Performance Mcap Company 1M 3M YTD 1Y 17-May Sun Pharma.Inds. -5 -4 3 -19 155026 Lupin -9 -11 -13 -20 58534 Cadila Health. 7 8 36 51 49590 Cipla -2 -5 -1 8 45340 Dr Reddy's Labs 2 -7 -12 -10 44822 Aurobindo Pharma -5 -7 -8 -20 36196 Torrent Pharma. -9 6 1 -4 22607 Glaxosmit Pharma -9 -10 -11 -29 20593 Glenmark Pharma. -20 -25 -20 -17 20126 Biocon -10 -10 5 60 19981 Apollo Hospitals 10 2 10 -3 18057 Natco Pharma -3 24 64 111 16559 Divi's Lab. -3 -17 -21 -43 16525 Ajanta Pharma -6 -6 -7 4 14525 Jubilant Life -8 8 21 96 12148 Alembic Pharma 0 10 2 6 11499 Syngene Int. -7 -6 -14 23 9683 Strides Arcolab -6 -12 -2 -11 9301 Pfizer -6 1 -4 -2 8041 Wockhardt -10 -3 3 -28 7503 Ipca Labs. -10 4 3 22 6924 Unichem Labs. -9 -1 3 4 2404 Indoco Remedies -8 -18 -16 -18 2011 Return (%) Market cap in | crore Global Indices Performance Company 1M 3M YTD 1Y 3Y 5Y S&P 500 Pharm Index (US) 0 1 7 6 8 15 NASDAQ Biotechnology (US) 2 0 12 15 9 20 S&P Pharmaceuticals (US) 1 1 9 5 1 13 DJ Pharma and Biotech (US) 1 1 8 9 8 16 DJ STOXX Healthcare (EU) 6 10 15 16 11 16 TOPIX Pharma Index (Japan) 5 3 5 2 17 20 MSCI World Pharm & Biotech 4 5 12 9 5 15 BI Global Spectalty-Generic Pharm 11 -6 -2 -18 -12 6 NSE Pharma -2 -4 0 -9 10 16 Return (%) Research Analyst Siddhant Khandekar [email protected] Mitesh Shah [email protected] Harshal Mehta [email protected]

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Page 1: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

May 18, 2017

Monthly Update

US pricing pressure steeper than expected The Q4 numbers released by Glenmark Pharma and Dr Reddy’s have once again showcased continuing (and perhaps worsening) pricing pressure in the US base business. Both the managements indicated high single digit to low double digit price erosion in the US in the backdrop of client consolidation and intense competition, mainly in the oral segment. In a major development, the government has, on record, made its intention to mandate doctors to write generic names of medicines on the prescription. This move is intended to bring down drug prices and expand access to affordable health solutions. The Medical Council of India has warned doctors of action if they fail to adhere to its guideline on prescribing drugs in generic names. The Medical Council of India's (MCI's) directive comes after Prime Minister Narendra Modi spoke of putting in place a legal framework to ensure doctors prescribed low cost generic medicines to patients. On the M&A front, Jubilant Life has acquired radio-pharmacy business of Triad Isotopes in the US. Triad recorded revenues in excess of US$225 million in CY16 with positive EBITDA and operates the second largest radio-pharmacy network in the US with more than 50 pharmacies. On the US regulatory front, Biocon’s Bangalore plant has received eight USFDA observations, Lupin’s Aurangabad and Goa plants received three and eight observations, respectively, while Dr Reddy’s Hyderabad (Bachupally) plant 3 received 11 observations. Aurobindo’s Unit 3 plant also received six observations. On the innovation front, the USFDA has cleared Glenmark’s investigational new drug (IND) application to initiate a Phase 1 study of GBR 1342 (oncology). It has also received IND approval for its proposed biosimilar GBR310 (respiratory). Finally, the Indian pharmaceutical market (IPM) grew 8.3% YoY to | 9474 crore for April. IPM growth was mainly driven by volumes – 3.4%, new product launches – 3.2% and price hikes- 1.4%. On a MAT basis, IPM growth was at 10.5% YoY to | 111859 crore. No respite on US pricing front; subdued start to Q4 earnings Almost all players with US franchisee from the I-direct universe are facing intense competition in existing products and client consolidation in the US, leading to price erosion to high single digit to low double digit. Increased USFDA scrutiny and frequencies of inspection/re-inspection is also somewhat delaying key approvals. Apart from this, strengthening of the rupee vis-à-vis the US dollar is also likely to weigh in the near term. Similarly, other issues/uncertainty in the US like pricing probe by the Department of Justice (DoJ), adapting to the bidding process and imposition of border tax on imported drugs are other near term overhangs. Front loading of investments, although useful for long term growth strategy, is also likely to impact near term profitability. For the time being, attractive valuations and decent growth expectations for FY18, FY19 are likely to be on the backburner due to these apprehensions. In the long run, however, we expect the earnings momentum to pick up on the back of incremental product launches largely on speciality, biosimilar and injectables front in the US besides normalising of Indian formulations growth.

Health CheckSector View

Neutral

Index Performance as on May 17, 2017

Return (%) 1M 3M YTD 1Y

CNX 500 4 10 20 27

Nifty 4 8 16 21

NSE Pharma -2 -4 0 -9

Return (%)

Stocks Performance Mcap

Company 1M 3M YTD 1Y 17-May

Sun Pharma.Inds. -5 -4 3 -19 155026

Lupin -9 -11 -13 -20 58534

Cadila Health. 7 8 36 51 49590

Cipla -2 -5 -1 8 45340

Dr Reddy's Labs 2 -7 -12 -10 44822

Aurobindo Pharma -5 -7 -8 -20 36196

Torrent Pharma. -9 6 1 -4 22607

Glaxosmit Pharma -9 -10 -11 -29 20593

Glenmark Pharma. -20 -25 -20 -17 20126

Biocon -10 -10 5 60 19981

Apollo Hospitals 10 2 10 -3 18057

Natco Pharma -3 24 64 111 16559

Divi's Lab. -3 -17 -21 -43 16525

Ajanta Pharma -6 -6 -7 4 14525

Jubilant Life -8 8 21 96 12148

Alembic Pharma 0 10 2 6 11499

Syngene Int. -7 -6 -14 23 9683

Strides Arcolab -6 -12 -2 -11 9301

Pfizer -6 1 -4 -2 8041

Wockhardt -10 -3 3 -28 7503

Ipca Labs. -10 4 3 22 6924

Unichem Labs. -9 -1 3 4 2404

Indoco Remedies -8 -18 -16 -18 2011

Return (%)

Market cap in | crore

Global Indices Performance

Company 1M 3M YTD 1Y 3Y 5Y

S&P 500 Pharm Index (US) 0 1 7 6 8 15

NASDAQ Biotechnology (US) 2 0 12 15 9 20

S&P Pharmaceuticals (US) 1 1 9 5 1 13

DJ Pharma and Biotech (US) 1 1 8 9 8 16

DJ STOXX Healthcare (EU) 6 10 15 16 11 16

TOPIX Pharma Index (Japan) 5 3 5 2 17 20

MSCI World Pharm & Biotech 4 5 12 9 5 15

BI Global Spectalty-Generic Pharm 11 -6 -2 -18 -12 6

NSE Pharma -2 -4 0 -9 10 16

Return (%)

Research Analyst

Siddhant Khandekar [email protected] Mitesh Shah [email protected] Harshal Mehta [email protected]

Page 2: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 2

IPM grows 8% YoY in April • The Indian pharmaceutical market (IPM) grew 8.3% YoY to | 9474 crore

in April. IPM growth was mainly driven by volumes – 3.4%, new product launches – 3.2% and price hikes- 1.4%

• The fixed dosage combination (FDCs) related market de-grew 18.4% resulting in a 0.6% squeeze to overall growth

• Drugs under NLEM list declined 5.3% to | 980 crore while non-NLEM drugs posted growth of 8.3% to | 8062 crore. Volume growth in NLEM and non-NLEM was 3.4% and 1.4%, respectively

• Among companies under I-direct coverage, Indoco, Glenmark, Torrent Ajanta, Sun Pharma, Natco, Ipca, Cadila and Dr Reddy’s have registered higher than industry growth rate

• Therapy wise, 10 therapies have outpaced IPM growth. Notable among them with growth rates- anti-diabetic – 17.8% and derma – 13.9%. On the other hand, anti-infectives remained flat YoY

• In all, 249 new brands were launched in April 2017 • On a MAT basis, IPM growth was at 10.5% YoY to | 111859 crore • Domestic and MNC companies have grown at 10.3% and 7.1%,

respectively, in March 2017 Exhibit 1: Domestic formulations - growth trend [

5.9

10.2

8.2

17.7

7.111

.4 13.7

9.2

15.5

20

10.1

9.6

8.3

-5

0

5

10

15

20

25

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 2: Companies growth in domestic market in April, 2017

20.9

8.5

18.0

-5.8

2.3

11.9

5.1 0.6

8.4

17.8

10.19.7

10.86.1

11.315.6

-10

-5

0

5

10

15

20

25

Ajan

ta

Alem

bic

Bioc

on

Cadi

la

Cipl

a

DRL

Glen

mar

k

GSK

Phar

ma

Indo

co

Ipca

Lab

s

Lupi

n

Nov

artis

Pfize

r

Sun

Phar

ma

Torre

nt

Unic

hem

(%)

Source: AIOCD data base, ICICIdirect.com Research

Therapy wise performance (| crore) Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)Anti-Infectives 1212 1205 0.6 1181 2.6Cardiac 1220 1123 8.7 1174 3.9GI 1158 1077 7.6 1038 11.6Anti Diabetic 897 761 17.8 860 4.2Vitamins 847 806 5.1 777 9.0Respiratory 613 582 5.3 664 -7.7Pain 640 596 7.5 590 8.5Neuro 585 555 5.4 553 5.8Derma 590 518 13.9 561 5.2Gynaecological 514 471 9.3 485 6.1Anti-Neoplastics 187 168 11.3 171 9.1Ophthal 194 179 8.6 172 12.7Vaccines 191 141 35.1 177 7.8Hormones 157 142 10.6 150 5.3Blood Related 127 105 20.8 109 16.5Urology 112 106 6.0 106 6.1Others 99 93 6.6 95 4.1Sex Stimulants 59 49 20.7 56 4.2Anti Malarials 27 33 -16.6 26 7.0Stomatologicals 43 41 5.7 39 11.3

Source: AIOCD data base

Top brands in Indian pharma market (MAT; | crore) Brand Company Therapy Apr' 17 YoY (%)Mixtard Abbott Anti Diabetic 514.0 3.2Glycomet Gp USV Anti Diabetic 423.0 26.6Spasmo ProxyvoWockhardt GI 390.0 21.6Lantus Sanofi India Anti Diabetic 344.0 22.8Galvus Met Novartis Anti Diabetic 336.0 20.3Liv 52 Himalaya GI 296.0 11.3Janumet MSD* Anti Diabetic 292.0 20.8Augmentin Gsk Anti-Infectives 284.0 -9.5Clavam Alkem Anti-Infectives 281.0 15.2Monocef Aristo Anti-Infectives 277.0 -0.6

Source: AIOCD data base Industry acute to chronic therapy ratio percentage…

Acute, 53522, 47.8%

Chronic, 35458, 31.7%

Sub-Chronic, 22879, 20.5%

Source: AIOCD data base; As per AIOCD MAT Apr 2017

Page 3: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 3

Sun Pharmaceuticals

507090

110130150

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Sun Pharma

Source: NSE, ICICIdirect.com Research Exhibit 3: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1 9.

6

8.3

5.4

3.4

7.6

20.4

17.2

13.7

20.4

9.4

9.4

8.0 11

.0

5.5

11.3

0

5

10

15

20

25

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Sun Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 4: Market share in Indian formulations market

8.5 8.6 8.6 8.5 8.4 8.4 8.58.8 8.6 8.88.6 8.7

8.8

6.06.57.07.58.08.59.09.5

10.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Sun Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 5: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Istamet Anti Diabetic 19.9 15.6 28.2 18.9 5.7

Rosuvas Cardiac 19.5 16.5 18.2 18.0 8.0

Volini Pain 18.7 20.5 -8.8 18.4 1.6

Gemer Anti Diabetic 17.3 14.2 21.8 16.0 7.7

Levipil Neuro 16.3 12.9 25.6 14.9 8.8

Susten Gynaecological 14.8 13.9 6.2 14.3 3.4

Pantocid Gastro Intestinal 12.1 12.0 0.5 11.7 2.8

Pantocid Dsr Gastro Intestinal 11.0 10.3 7.2 10.3 7.1

Revital H Vitamins 9.5 12.5 -24.1 9.5 -0.3

Storvas Cardiac 9.2 10.5 -12.7 9.1 0.3

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 6: Contribution of therapies to domestic sales (MAT Apr’ 17)

z

Cardiac31%

Neuro

Gastro Intestinal

18%

Anti-Infectives16%

Derma8%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 7: Therapy wise performance (| crore)

Therapy Mar' 17 Mar' 16 YoY (%) Feb' 17 MoM (%)

Cardiac 152.4 136.1 11.9 149.4 2.0

Neuro 141.5 123.1 15.0 135.9 4.1

Gastro Intestinal 92.1 83.3 10.5 90.2 2.1

Anti-Infectives 78.1 84.1 -7.2 84.2 -7.2

Derma 45.4 33.6 35.0 73.9 -38.5

Anti Diabetic 76.6 64.2 19.4 51.5 48.9

Vitamins 30.0 28.5 5.4 42.9 -30.1

Pain 52.5 50.1 4.7 31.4 67.2

Respiratory 29.5 24.5 20.8 29.6 -0.4

Gynaecological 32.2 30.7 4.8 31.0 3.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 3777, 39.3%

Chronic, 4484, 46.6%

Sub-Chronic,

1355, 14.1%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

18%

9%

7%

10%

56%

Top 10 11 to 20 21 to 30 31 to 50 Others

Page 4: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 4

Cipla

Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Cipla

Source: NSE, ICICIdirect.com Research

Exhibit 8: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1

9.6

8.3

1.8 5.

7

8.2

19.3

18.7

9.5

5.8

10.1

2.1 3.9

1.4

6.3

0.6

0

5

10

15

20

25

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 9: Market share in Indian formulations market

5.0

4.6 4.6

4.94.8

4.7 4.74.8

4.94.7

4.8

4.6 4.6

4.0

4.2

4.4

4.6

4.8

5.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Cipla

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 10: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Foracort Respiratory 20.4 18.3 11.4 19.0 7.5

Budecort Respiratory 10.8 14.1 -23.5 11.9 -9.8

Seroflo Respiratory 12.3 11.3 9.4 11.9 4.0

Asthalin Respiratory 10.6 11.3 -5.4 11.1 -4.0

Duolin Respiratory 15.3 10.7 42.5 15.3 -0.1

Aerocort Respiratory 9.3 9.0 3.6 8.5 9.6

Azee Anti-Infectives 6.2 7.8 -20.6 5.6 11.1

Montair Lc Respiratory 6.5 7.1 -9.3 7.8 -16.7

Dytor Cardiac 7.2 6.5 10.3 7.2 -0.2

Emeset Gastro Intestinal 6.4 6.3 1.4 4.5 42.3

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 11: Contribution of therapies to domestic sales (MAT Apr’ 17)

Respiratory32%

Anti-Infectives24%

Cardiac12%

Gastro Intestinal

8%

Urology5%

Other19%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 12: Therapy wise performance (| crore)

Therapy Apr ' 17 Apr' 16 YoY (%) Mar' 17 MoM (% )

Respiratory 131.7 127.9 3.0 133.3 -1.2

Ant i- Infectives 108.9 113.1 -3.7 99.1 9.9

Cardiac 54.5 55.7 -2.0 53.1 2.7

Gastro Intest inal 37.4 35.5 5.4 30.3 23.6

Urology 22.3 20.0 1 1.3 22.4 -0.5

Neuro 16.2 16.6 -2.5 15.6 4.0

Ophthal 16.1 16.0 0.6 14.8 9.2

Pain 12.8 13.7 -6.4 12.3 4.6

Derma 10.7 11.8 -9.0 9.8 9.6

Gynaecological 7.7 8.8 -1 2.0 6.7 14.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 2391, 45.3%

Chronic, 2207, 41.8%

Sub-Chronic,

680, 12.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

24%

12%

8%12%

44%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 5: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 5

Dr. Reddy’s Labs

Stock Performance) Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Dr. Reddys

Source: NSE, ICICIdirect.com Research Exhibit 13: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

-1.6

4.1

1.6 5.

1

17.2

22.5

7.3 8.

4

5.0

-2.6

0.4

-3.4

12.6

-5

0

5

10

15

20

25

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Dr. Reddys Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 14: Market share in Indian formulations market

2.1 2.1 2.3 2.1 2.22.4

2.2 2.3 2.4 2.3 2.3 2.32.1

0.6

1.1

1.6

2.1

2.6

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Dr. Reddys Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 15: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Omez Gastro Intestinal 8.7 10.3 -15.7 8.9 -1.7

Omez D Gastro Intestinal 8.1 7.4 9.2 8.2 -1.9

Econorm Gastro Intestinal 6.1 6.4 -3.5 6.2 -0.4

Stamlo Cardiac 4.5 5.1 -12.6 4.3 4.0

Nise Pain 4.2 4.9 -14.4 4.0 4.9

Stamlo Beta Cardiac 4.5 4.3 4.2 3.9 13.9

Razo D Gastro Intestinal 4.8 4.1 18.3 4.9 -2.3

Grafeel Anti-Neoplastics 2.5 3.9 -35.4 2.8 -8.5

Mintop Derma 2.8 3.7 -24.0 2.9 -3.6

Atarax Respiratory 5.3 3.7 42.8 5.3 -1.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 16: Contribution of therapies to domestic sales (MAT Apr’ 17) Gastro

Intestinal21%

Anti-Neoplastics

14%

Cardiac13%

Respiratory9%

Anti-Infectives8%

Other35%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 17: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Gastro Intestinal 42.8 40.4 5.9 43.2 -1.0

Anti-Neoplastics 21.0 19.7 6.4 25.9 -19.1

Cardiac 28.9 27.9 3.8 27.7 4.2

Respiratory 17.8 14.1 26.4 20.4 -13.0

Anti-Infectives 14.4 13.3 8.0 15.5 -7.4

Anti Diabetic 14.0 13.1 6.4 13.9 0.5

Pain 13.0 12.4 5.6 12.8 2.2

Derma 11.7 12.1 -3.8 12.6 -7.3

Urology 8.6 8.1 5.9 8.3 3.6

Neuro 7.8 7.7 1.9 7.2 9.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 1320, 52.3%

Chronic, 694, 27.5%

Sub-Chronic,

509, 20.2%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

27%

16%

10%13%

34%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 6: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 6

Lupin

Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Lupin

Source: NSE, ICICIdirect.com Research

Exhibit 18: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

10.1 11

.8

4.6

11.4 12

.6

19.9 21

.2

17.7

5.6

8.7

5.6

10.2

10.8

0

5

10

15

20

25

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 19: Market share in Indian formulations market

3.2 3.3

3.1 3.2 3.2

3.5

3.6

3.3 3.3 3.33.3

3.33.3

3.0

3.2

3.4

3.6

3.8

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Lupin

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 20: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Gluconorm-G Anti Diabetic 16.8 13.3 26.8 14.9 12.6

Tonact Cardiac 7.4 8.7 -14.6 7.4 0.7

Budamate Respiratory 8.6 7.4 15.7 9.0 -4.9

Rablet-D Gastro Intestinal 4.8 5.0 -5.6 4.7 1.2

Ramistar Cardiac 3.3 4.6 -29.2 3.3 -0.4

Rablet Gastro Intestinal 5.1 4.5 14.1 4.1 24.2

Esiflo Respiratory 4.2 4.0 4.9 4.7 -11.4

R-Cinex Anti-Infectives 3.8 3.9 -2.0 3.4 14.6

Telekast-L Respiratory 4.0 3.5 16.1 4.0 0.4

Clopitab-A Cardiac 3.6 3.5 3.9 3.6 -0.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 21: Contribution of therapies to domestic sales (MAT Apr’ 17) 24%

Anti-Infectives19%

Anti Diabetic14%Respiratory

13%

Gastro Intestinal

8%

Other22%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 22: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Cardiac 78.8 55.6 41.8 75.8 4.0

Anti-Infectives 52.7 34.2 53.9 51.3 2.6

Anti Diabetic 49.5 33.9 46.0 44.2 11.9

Respiratory 39.6 23.4 69.6 41.0 -3.5

Gastro Intestinal 25.2 14.9 68.9 23.0 9.6

Vitamins 15.1 14.9 1.2 13.6 11.2

Neuro 15.0 12.2 23.5 14.5 3.6

Pain 12.3 9.8 25.4 12.1 2.0

Gynaecological 13.2 1.6 722.1 12.0 9.9

Urology 2.5 2.1 14.8 2.2 12.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 1187, 32.1%

Chronic, 1853, 50.1%

Sub-Chronic,

662, 17.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

20%

11%

8%12%

49%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 7: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 7

Cadila Healthcare

Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Cadila Healthcare

Source: NSE, ICICIdirect.com Research Exhibit 23: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1

9.6

8.3

6.2

9.4

4.0

6.7

10.9

14.8

14.3 16

.1

11.3

17.7

10.6

12.6

8.5

02468

101214161820

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 24: Market share in Indian formulations market

4.3 4.24.0 4.0 4.0

4.14.3

4.24.3

4.64.4

4.34.4

3.0

3.4

3.8

4.2

4.6

5.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Cadila Healthcare

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 25: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Skinlite Derma 14.6 16.7 -12.4 19.0 -23.2

Mifegest Kit Gynaecological 12.3 12.9 -4.6 13.3 -7.0

Atorva Cardiac 9.5 11.6 -17.8 9.4 0.9

Pantodac Gastro Intestinal 10.1 8.9 13.1 9.3 8.1

Deriphyllin Respiratory 9.7 8.6 12.9 8.8 10.7

Zyrop Blood Related 4.9 6.9 -29.6 3.5 38.5

Thrombophob Pain 7.8 5.8 33.5 5.8 32.7

Dexona Hormones 4.8 5.8 -16.4 5.2 -6.7

Amlodac Cardiac 5.6 5.8 -3.4 5.2 6.0

Formonide Respiratory 5.5 5.3 2.8 5.6 -1.9

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 26: Contribution of therapies to domestic sales (MAT Apr’ 17) Anti-Infectives

15%

Cardiac14%

Gastro Intestinal

12%

Respiratory10%

Gynaecological10%

Other39%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 27: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Anti-Infectives 58.6 52.7 11.3 54.3 8.0

Cardiac 60.9 57.0 6.8 58.7 3.7

Gastro Intestinal 48.3 46.5 3.8 46.4 4.1

Respiratory 39.7 35.2 12.6 40.3 -1.6

Gynaecological 45.2 42.5 6.2 44.4 1.8

Pain 41.3 34.3 20.5 35.7 15.7

Derma 27.2 27.6 -1.5 33.1 -17.9

Anti-Neoplastics 18.1 20.3 -11.1 20.6 -12.1

Vitamins 17.0 14.3 18.8 17.2 -1.2

Hormones 14.4 7.7 87.0 14.3 0.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 2361, 49.7%

Chronic, 1510, 31.8%

Sub-Chronic,

876, 18.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

21%

12%

9%

12%

46%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 8: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 8

GlaxoSmithKline

Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma GSK Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 28: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2 11

.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

-8.5 -0

.6

-6.7

3.6

4.2

-10.

8

4.3 5.7

9.3

-3.4 -0

.4

-5.9

10.1

-15

-10

-5

0

5

10

15

20

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market GSK Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 29: Market share in Indian formulations market

3.1 3.0 2.9 3.0 2.9 2.9 2.9 3.0 3.0 3.2 3.2 3.1 3.1

0.6

1.1

1.6

2.1

2.6

3.1

3.6

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

GSK Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 30: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Augmentin Anti-Infectives 24.3 23.2 4.6 24.0 1.2

Synflorix Vaccines 22.9 17.9 28.1 23.5 -2.4

Calpol Pain 13.6 14.9 -8.2 12.8 6.5

Zinetac Gastro Intestinal 13.3 14.0 -5.0 11.7 14.0

Betnovate N Derma 15.6 12.2 27.1 15.8 -1.3

Rabipur Vaccines 2.4 11.0 -78.0 2.3 3.8

Eltroxin Hormones 12.9 11.0 17.3 12.2 5.7

Betnovate C Derma 16.3 10.7 52.1 14.3 13.9

Ceftum Anti-Infectives 10.2 10.1 0.8 10.0 1.4

Rotarix Vaccines 10.3 9.6 7.3 8.1 27.9

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 31: Contribution of therapies to domestic sales (MAT Apr’ 17) Anti-Infectives

21%

Vaccines18%

Derma18%

Pain 9%

Vitamins 8%

Other26%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 32: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Anti-Infectives 57.9 59.0 -1.8 56.6 2.2

Vaccines 58.6 53.0 10.6 55.7 5.2

Derma 67.1 43.5 54.2 62.4 7.6

Pain 21.7 24.4 -11.4 21.1 2.7

Vitamins 25.7 20.3 26.3 22.3 15.1

Hormones 21.0 19.4 8.5 20.2 4.0

Respiratory 15.4 19.1 -19.1 17.7 -12.7

Gastro Intestinal 15.7 16.6 -5.4 14.1 11.4

Cardiac 4.5 4.1 10.1 4.0 14.2

Gynaecological 2.1 3.3 -35.8 1.8 20.0

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 2217, 65.7%

Chronic, 428, 12.7%

Sub-Chronic,

730, 21.6%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

50%

17%

9%

11%

13%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 9: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 9

Wockhardt

Stock Performance

050

100150200250300350400

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Wockhardt

Source: NSE, ICICIdirect.com Research Exhibit 33: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

4.5

9.5

1.4

2.1

17.4

10.8

4.0 3.0

18.8

13.2

11.9

11.1

24.3

0

5

10

15

20

25

30A

pr-1

6

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 34: Market share in Indian formulations market

1.2 1.2 1.2 1.2 1.2 1.3 1.3 1.4 1.4 1.4 1.4 1.31.4

0.00.20.40.60.81.01.21.41.6

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Wockhardt

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 35: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Spasmo Proxyvon PluGastro Intestinal 37.3 24.3 53.2 33.8 10.2

Practin Vitamins 8.0 8.0 1.2 7.2 12.2

Wepox Blood Related 7.9 0.9 786.2 1.9 317.4

Methycobal Vitamins 4.7 4.6 2.8 3.7 27.4

Tryptomer Neuro 4.6 6.1 -24.3 4.1 12.8

Biovac V Vaccines 4.0 2.9 36.9 3.9 4.2

Biovac A Vaccines 4.0 2.5 62.5 3.9 1.9

Butaproxyvon Pain 3.8 2.5 54.1 2.5 51.2

Bro Zedex Respiratory 3.2 3.4 -3.7 3.9 -16.1

Wosulin Anti Diabetic 2.7 2.9 -6.6 2.7 0.2

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 36: Contribution of therapies to domestic sales (MAT Apr’ 17) Gastro

Intestinal28%

Vitamins 15%Respiratory

12%

Neuro 7%

Anti Diabetic6%

Other32%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 37: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Gastro Intestinal 39.5 25.7 53.8 35.6 10.9

Vitamins 19.4 18.7 3.7 16.8 15.5

Respiratory 12.6 10.0 26.7 13.2 -4.1

Neuro 9.2 10.6 -13.3 8.0 14.7

Anti Diabetic 8.7 8.5 2.7 7.6 15.0

Derma 7.3 7.4 -1.7 6.7 8.4

Vaccines 8.4 5.5 53.2 8.9 -6.0

Pain 9.7 6.8 42.9 7.8 24.6

Anti-Infectives 6.6 7.0 -4.9 6.9 -3.7

Blood Related 8.2 1.1 640.4 2.1 284.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 1022, 69.4%

Chronic, 291,

19.8%

Sub-Chronic,

159, 10.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

57%

13%

8%

8%

14%

Top 10 11 to 20 21 to 30 31 to 50 Others

Page 10: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 10

Glenmark Pharmaceuticals

Stock Performance

6080

100120140160180200

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17CNX Pharma Glenmark

Source: NSE, ICICIdirect.com Research

Exhibit 38: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2 11

.4

17.7

13.7

9.2

15.5

7.6 10

.1

9.6

8.2 8.5

7.2 8.3

20.7

11.6

7.6

18.8

5.7

15.6

13.5 15

.7 17.8

7.1

8.3

-4

4

12

20

28

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Glenmark Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 39: Market share in Indian formulations market

2.3

2.1

2.3 2.3

2.42.3

2.42.5 2.5

2.62.5

2.5 2.5

2.1

2.2

2.3

2.4

2.5

2.6

2.7

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Glenmark Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 40: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Telma H Cardiac 16.1 13.6 18.7 14.7 9.6

Telma Cardiac 17.4 13.2 31.0 14.3 21.1

Candid Derma 13.7 11.7 16.6 7.7 76.7

Ascoril Plus Respiratory 10.9 8.9 22.3 9.6 14.2

Candid-B Derma 7.8 8.7 -9.4 7.2 9.6

Telma Am Cardiac 7.9 7.4 6.8 8.3 -4.2

Ascoril Ls Respiratory 5.0 3.8 31.2 4.8 4.4

Onabet Derma 3.7 3.3 10.6 3.6 2.3

Zitamet Plus Anti Diabetic 4.4 3.0 46.8 3.9 14.2

Dubagest Gynaecological 2.7 2.9 -8.0 2.7 -0.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 41: Contribution of therapies to domestic sales (MAT Apr’ 17)

Derma28%

Cardiac22%

Respiratory16%

Anti-Infectives14%

Anti Diabetic6%

Other14%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 42: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Derma 67.3 62.9 6.9 61.2 10.0

Cardiac 57.0 48.1 18.5 52.8 7.9

Respiratory 35.2 26.9 30.9 35.2 -0.2

Anti-Infectives 29.6 23.8 24.4 30.5 -3.0

Anti Diabetic 15.3 15.0 1.4 14.0 8.9

Gastro Intestinal 8.4 5.7 48.4 8.1 3.6

Gynaecological 7.1 5.1 38.5 6.2 14.8

Vitamins 4.6 5.7 -18.1 4.6 0.6

Pain 3.8 4.1 -7.8 3.8 -0.8

Ophthal 3.0 2.4 22.8 2.5 18.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 1125, 41.9%

Chronic, 934, 34.7%

Sub-Chronic,

628, 23.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

34%

12%10%

14%

30%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 11: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 11

Torrent Pharmaceuticals

Stock Performance

4080

120160200

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Torrent Pharma

Source: NSE, ICICIdirect.com Research Exhibit 43: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1

9.6

8.3

5.4

10.6

22.1

7.9 8.0

17.5 21

.3

14.5

14.7 17

.2

9.9 10

.5

15.6

0

5

10

15

20

25

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Torrent Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 44: Market share in Indian formulations market

2.3 2.32.4

2.32.2 2.2 2.2

2.3 2.3 2.3 2.42.4

2.3

1.5

1.7

1.9

2.1

2.3

2.5

2.7

2.9

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Torrent Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 45: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Shelcal Vitamins 15.6 14.3 9.2 13.2 18.9

Chymoral Forte Pain 9.0 7.9 13.9 8.2 9.9

Azulix-Mf Anti Diabetic 8.3 5.1 62.9 7.3 13.5

Nikoran Cardiac 8.1 8.1 0.1 7.5 7.5

Nebicard Cardiac 7.3 5.3 37.3 6.8 7.2

Dilzem Cardiac 6.9 5.8 18.2 6.4 7.3

Nexpro Rd Gastro Intestinal 6.6 5.1 29.8 5.9 12.3

Nexpro Gastro Intestinal 5.3 4.3 23.0 4.8 11.5

Shelcal Ct Vitamins 4.4 3.9 11.1 3.4 27.3

Rozucor Cardiac 4.0 3.7 7.8 3.6 11.4

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 46: Contribution of therapies to domestic sales (MAT Apr’ 17)

Cardiac31%

Neuro 17%

Gastro Intestinal

15%

Vitamins 14%

Anti Diabetic7%

Other16%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 47: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Cardiac 68.9 61.2 12.6 62.8 9.7

Neuro 40.6 33.6 20.9 36.8 10.1

Gastro Intestinal 37.1 31.0 19.6 32.5 14.2

Vitamins 31.7 29.2 8.4 26.9 17.8

Anti Diabetic 18.6 12.5 49.1 16.5 13.3

Pain 15.6 13.8 13.1 14.0 11.2

Anti-Infectives 6.1 7.1 -14.2 6.1 1.0

Derma 7.1 6.2 14.1 6.4 10.4

Gynaecological 2.5 2.5 0.3 2.3 7.8

Respiratory 0.8 0.4 83.3 0.9 -7.6

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 587, 22.7%

Chronic, 1385, 53.6%

Sub-Chronic,

612, 23.7%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

32%

14%

9%12%

33%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 12: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 12

Ipca Laboratories

Stock Performance

5075

100125150

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Ipca

Source: NSE, ICICIdirect.com Research Exhibit 48: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2 11

.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

3.5

3.5

4.6

18.5

28.7

8.6

5.2

9.5

2.9

3.5

13.1

9.7

1.9

0

5

10

15

20

25

30

35

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Ipca Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 49: Market share in Indian formulations market

1.2 1.2 1.21.3 1.4 1.4 1.3

1.2 1.2 1.1 1.2 1.2 1.2

0.0

0.5

1.0

1.5

2.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Ipca Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 50: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Zerodol P Pain 8.6 7.9 9.0 5.0 72.2

Zerodol Sp Pain 9.4 7.8 20.6 8.3 12.9

Hcqs Anti Malarials 6.4 5.9 8.2 6.1 4.9

Glycinorm M Anti Diabetic 3.6 3.1 14.2 3.6 0.1

Rapither-Ab Anti Malarials 2.1 2.9 -28.6 1.6 29.4

Folitrax Anti-Neoplastics 3.4 2.7 24.4 3.2 6.9

Zerodol Pain 2.4 2.5 -3.4 2.1 15.3

Larinate Anti Malarials 2.6 2.5 4.7 2.1 21.5

Lariago Anti Malarials 1.7 2.1 -19.1 1.7 -2.5

Ctd Cardiac 2.2 2.0 5.7 2.1 5.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 51: Contribution of therapies to domestic sales (MAT Apr’ 17)

Pain 26%

Anti Malarials19%

Cardiac16%

Gastro Intestinal

8%

Anti-Infectives6%

Other25%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 52: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Pain 34.1 30.0 13.6 27.6 23.5

Anti Malarials 15.4 16.4 -6.3 14.1 8.8

Cardiac 19.8 18.7 5.6 19.3 2.3

Gastro Intestinal 9.4 9.4 0.7 8.6 10.3

Anti-Infectives 6.7 5.7 17.5 5.8 15.2

Anti Diabetic 6.4 5.7 11.6 6.4 -0.7

Anti-Neoplastics 5.0 4.6 8.6 5.0 0.7

Neuro 4.8 3.6 33.2 5.1 -5.9

Respiratory 3.7 3.5 4.7 4.4 -16.1

Derma 4.0 2.8 44.3 4.4 -9.3

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 902, 65.3%

Chronic, 381, 27.6%

Sub-Chronic, 98,

7.1%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

37%

16%11%

13%

23%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 13: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 13

Biocon

Stock Performance

60100140180220

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17CNX Pharma Biocon

Source: NSE, ICICIdirect.com Research

Exhibit 53: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

8.4

8.3

2.0

2.2

9.8

10.5

2.5

26.0

10.5

11.2

5.1 1.8

20.9

0

5

10

15

20

25

30

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 54: Market share in Indian formulations market

0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.3 0.4 0.3 0.40.3

0.0

0.2

0.4

0.6

0.8

1.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Biocon

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 55: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Insugen Anti Diabetic 9.6 7.5 27.7 9.0 7.3

Basalog Anti Diabetic 6.7 5.1 30.6 6.0 11.1

Canmab Anti-Neoplastics 4.7 2.2 116.0 2.5 89.6

Erypro Blood Related 1.3 1.9 -32.7 1.5 -16.7

Abraxane Anti-Neoplastics 0.1 1.7 -96.5 0.0 NA

Insugen R Anti Diabetic 1.9 1.4 33.4 1.9 0.3

Blisto Mf Anti Diabetic 1.5 1.2 17.5 1.4 4.8

Biomab Egfr Anti-Neoplastics 0.9 1.0 -14.7 0.1 500.0

Psorid Anti-Neoplastics 1.3 0.6 123.6 1.0 33.7

Insugen N Anti Diabetic 0.6 0.6 11.1 0.7 -7.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 56: Contribution of therapies to domestic sales (MAT Apr’ 17)

Anti Diabetic58%

Anti-Neoplastics

21%

Blood Related9%

Cardiac5%

Derma3%

Other 4%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 57: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Anti Diabetic 21.8 17.0 28.4 20.5 6.3

Anti-Neoplastics 8.3 7.2 14.3 4.6 78.0

Blood Related 1.3 1.9 -30.7 1.6 -15.5

Cardiac 1.5 1.5 1.3 1.8 -14.0

Derma 0.9 0.7 24.4 0.8 9.1

Anti-Infectives 1.1 0.6 86.2 1.1 -3.4

Others 0.3 0.2 64.9 0.4 -16.1

Gastro Intestinal 0.1 0.0 96.1 0.0 140.5

Vitamins 0.1 0.1 -24.8 0.1 -14.4

Pain 0.1 0.0 167.5 0.1 -47.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 73, 19.7%

Chronic, 267, 72.3%

Sub-Chronic, 30,

8.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

79%9%

5%

5%

2%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 14: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 14

Pfizer

Stock Performance

4080

120160200

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Pfizer

Source: NSE, ICICIdirect.com Research Exhibit 58: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

2.5

7.4

-0.9

2.8

6.9

2.3

0.5 6.

6

-3.2

-1.5

0.7

-1.5

-5.8

-10

-5

0

5

10

15

20

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 59: Market share in Indian formulations market

2.92.8

2.6 2.7 2.6 2.6 2.7 2.6 2.6 2.6 2.6 2.5 2.5

2.0

2.4

2.8

3.2

3.6

4.0

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Pfizer

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 60: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Becosules Vitamins 20.4 18.8 8.8 16.5 24.0

Dolonex Pain 13.3 11.6 14.8 11.3 17.5

Prevenar 13 Vaccines 12.5 4.2 200.1 14.2 -12.5

Magnex Anti-Infectives 11.8 9.4 25.5 11.1 5.9

Minipress Xl Cardiac 11.7 15.4 -23.7 12.5 -6.0

Gelusil Mps Gastro Intestinal 10.6 10.8 -2.3 10.2 3.3

Mucaine Gastro Intestinal 9.5 9.7 -3.0 9.4 0.9

Wysolone Hormones 8.0 7.8 2.1 7.4 7.9

Folvite Blood Related 6.9 7.3 -5.3 6.4 7.2

Ovral L Gynaecological 6.3 6.0 5.3 5.8 8.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 61: Contribution of therapies to domestic sales (MAT Apr’ 17) Anti-Infectives14%

Gastro Intestinal

10%

Respiratory10%

Vitamins 10%Hormones

10%

Other46%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 62: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Anti-Infectives 33.5 34.6 -3.2 32.9 1.7

Gastro Intestinal 25.7 26.0 -1.2 23.6 9.0

Respiratory 9.7 34.3 -71.8 12.6 -23.4

Vitamins 25.1 24.2 3.8 20.9 20.0

Hormones 22.2 20.9 6.2 20.1 10.3

Gynaecological 23.3 21.0 11.0 21.7 7.6

Cardiac 17.1 21.2 -19.6 18.0 -5.3

Neuro 18.3 19.7 -6.9 18.2 0.5

Pain 16.9 15.0 12.6 15.2 11.8

Vaccines 17.8 7.4 140.3 19.7 -9.7

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 1864, 63.8%

Chronic, 476, 16.3%

Sub-Chronic,

583, 19.9%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

47%

20%

11%

11%

11%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 15: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 15

Novartis

Stock Performance

40

90

140

190

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Novartis India

Source: NSE, ICICIdirect.com Research

Exhibit 63: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1

9.6

8.3

17.7

14.6

5.4

5.0 5.6

14.4

5.1

8.5 6.

1

02468

101214161820

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Novartis India

8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 64: Market share in Indian formulations market

1.0 1.0 1.0 0.9 0.9 1.0 0.91.0

1.00.9

1.0 1.01.0

0.0

0.2

0.4

0.6

0.8

1.0

1.2

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Novartis India

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 65: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Galvus Met Anti Diabetic 33.3 25.2 32.0 33.2 0.5

Voveran Pain 19.6 19.5 0.3 17.4 12.2

Galvus Anti Diabetic 10.1 10.1 0.7 9.8 3.0

Tegrital Neuro 4.7 5.0 -6.4 4.5 5.7

Voveran Pain 3.1 3.4 -10.6 2.9 6.7

Regestrone Gynaecological 2.7 3.0 -8.8 2.4 15.1

Methergin Gynaecological 2.7 2.5 8.2 2.4 13.6

Syntocinon Gynaecological 2.1 2.0 3.4 2.1 0.0

Macalvit Vitamins 1.9 2.0 -6.9 1.6 16.3

Calcium Sandoz Vitamins 2.2 1.9 12.3 1.8 19.5

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 66: Contribution of therapies to domestic sales (MAT Apr’ 17)

Anti Diabetic43%

Pain 26%

Vitamins 10%

Gynaecological8%

Neuro 5%

Other8%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 67: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Anti Diabetic 43.8 35.9 22.2 43.3 1.1

Pain 23.6 24.4 -3.1 21.0 12.3

Vitamins 8.8 9.6 -9.0 9.0 -3.1

Gynaecological 7.7 7.8 -1.8 7.0 9.0

Neuro 4.7 5.1 -7.0 4.5 5.7

Anti-Infectives 2.7 3.6 -24.5 2.2 23.2

Respiratory 1.5 1.8 -18.5 1.6 -5.4

Cardiac 1.3 0.8 62.2 1.2 14.0

Anti-Neoplastics 0.8 0.2 224.6 0.7 10.5

Hormones 0.4 0.1 236.0 0.1 303.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 409, 37.8%

Chronic, 527, 48.6%

Sub-Chronic,

147, 13.6%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

84%

9%3%3%1%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 16: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 16

Unichem Laboratories

Stock Performance

70100130160

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Unichem Labs

Source: NSE, ICICIdirect.com Research

Exhibit 68: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

8.4 11

.3 12.3

18.8

22.2

26.7

22.1

15.9

10.8

8.1 8.8 9.2

2.3

0

5

10

15

20

25

30

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Unichem Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 69: Market share in Indian formulations market

0.9

0.9 0.9

0.9 0.90.9

0.9 0.90.9 0.9

0.90.9

0.8

0.8

0.8

0.8

0.8

0.9

0.9

0.9

0.9

0.9

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Unichem Lab

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 70: Top 10 brands performance (| crore)

Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Losar H Cardiac 8.0 7.9 1.4 7.6 4.3

Losar Cardiac 6.4 5.8 10.4 6.2 2.4

Unienzyme Gastro Intestinal 5.0 5.1 -3.2 5.5 -8.8

Ampoxin Anti-Infectives 4.8 5.1 -6.5 5.2 -7.9

Vizylac Gastro Intestinal 3.0 2.8 4.9 2.6 12.9

Trika Neuro 2.0 2.0 2.7 2.1 -3.8

Serta Neuro 1.8 2.0 -8.0 2.0 -7.1

Unistar (Unichem) Cardiac 1.8 1.6 15.2 1.7 7.3

Arkamin Cardiac 1.6 1.4 15.8 1.6 2.0

Telsar Cardiac 1.4 1.3 8.0 1.3 4.8

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 71: Contribution of therapies to domestic sales (MAT Apr’ 17)

Cardiac42%

Anti-Infectives16%

Neuro 14%

Gastro Intestinal

12%

Anti Diabetic5%

Other11%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 72: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Cardiac 34.7 33.6 3.5 33.6 3.2

Anti-Infectives 10.5 11.0 -4.2 11.2 -6.2

Neuro 11.7 11.2 5.1 11.6 1.2

Gastro Intestinal 9.3 9.3 0.4 9.4 -1.0

Anti Diabetic 5.0 3.5 41.2 4.7 4.8

Pain 2.9 2.9 -0.8 3.0 -4.2

Vitamins 1.6 1.8 -10.6 1.7 -5.9

Respiratory 1.3 1.6 -15.4 1.5 -9.9

Derma 1.5 1.9 -20.3 1.5 -1.9

Gynaecological 0.2 0.4 -37.8 0.2 -9.9

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 341,

34.3%

Chronic, 593,

59.7%

Sub-Chronic, 60, 6.0%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

32%

14%

9%12%

33%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 17: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 17

Indoco Remedies

Stock Performance

6080

100120140

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Indoco

Source: NSE, ICICIdirect.com Research

Exhibit 73: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2 11

.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

28.6

34.8

-0.2

5.4

11.4

18.4

6.4 9.6

5.8

17.7

16.2

18.7

18.0

-5

0

5

10

15

20

25

30

35

40

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 74: Market share in Indian formulations market

0.6 0.60.7

0.8 0.80.7 0.7 0.7 0.7

0.7 0.8 0.70.7

0.50.60.60.70.70.80.80.90.91.01.01.11.1

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indoco Remedies

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 75: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)

Febrex Plus Respiratory 5.0 4.3 16.6 6.1 -19.0

Cital Urology 3.4 3.9 -11.9 3.1 11.2

Cyclopam Gastro Intestinal 4.3 3.6 18.8 4.1 4.6

Sensodent-K Stomatologicals 3.3 3.2 3.9 2.8 18.2

Oxipod Anti-Infectives 3.5 2.6 33.4 3.7 -5.0

Atm Anti-Infectives 2.0 1.9 4.6 2.5 -20.3

Cloben G Derma 2.0 1.8 9.3 1.9 4.2

Sensodent-Kf Stomatologicals 1.7 1.7 -0.2 1.5 15.7

Cyclopam Gastro Intestinal 2.3 1.7 32.5 2.1 6.0

Sensoform Stomatologicals 1.8 1.7 6.9 1.5 19.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 76: Contribution of therapies to domestic sales (MAT Apr’ 17) Respiratory

19%

Anti-Infectives18%

Stomatologicals

15%

Gastro Intestinal

14%

Vitamins 8%

Other26%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 77: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Respiratory 8.7 7.5 15.5 10.9 -20.4

Anti-Infectives 9.9 8.5 16.2 10.9 -9.5

Stomatologicals 10.7 9.8 9.7 9.6 12.2

Gastro Intestinal 9.8 8.0 21.4 9.3 5.4

Vitamins 6.1 4.1 47.1 6.1 -0.9

Urology 3.8 4.2 -9.9 3.5 10.6

Ophthal 3.9 2.8 36.9 3.7 4.6

Pain 2.5 2.3 9.5 2.8 -7.5

Derma 2.6 2.3 12.4 2.6 1.0

Anti Diabetic 2.6 1.7 55.1 2.4 8.4

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 654,

81.9%

Chronic, 45, 5.7%

Sub-Chronic,

99, 12.5%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

47%

15%

9%

11%

18%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 18: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 18

Ajanta Pharmaceuticals

Stock Performance

4090

140190240290

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Ajanta

Source: NSE, ICICIdirect.com Research

Exhibit 78: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6

10.1

7.1

9.6

8.3

19.4

19.3

19.2

14.5 16

.1

8.3

12.5 13

.4

10.6

18.4

8.7

13.8

11.9

0

5

10

15

20

25

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Indian Pharma Market Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 79: Market share in Indian formulations market

0.6

0.7 0.7

0.60.6

0.60.6

0.60.6

0.7

0.6 0.60.6

0.50.50.50.60.60.60.60.60.70.70.7

Apr

-16

May

-16

Jun-

16

Jul-1

6

Aug

-16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr

-17

(%)

Ajanta Pharma

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 80: Top 10 brands performance (| crore) Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)Met Xl Cardiac 6.2 5.1 21.7 6.6 -6.3

Melacare Derma 4.6 3.6 27.4 3.4 35.1

Atorfit Cv Cardiac 4.1 4.1 -1.1 4.1 0.5

Feburic Pain 1.8 1.6 16.3 1.7 6.1

Rosufit Cv Cardiac 1.6 1.7 -4.2 1.5 8.8

Soft Drops Ophthal 1.6 1.4 13.5 1.6 1.9

Rosutor Gold Cardiac 1.6 1.1 39.2 1.4 14.7

Met Xl Am Cardiac 1.5 1.5 -0.2 1.6 -3.5

Cinod Cardiac 1.3 1.1 16.4 1.4 -6.4

Olopat Ophthal 1.0 1.0 5.0 0.9 14.1

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 81: Contribution of therapies to domestic sales (MAT Apr’ 17)

Cardiac38%

Ophthal 24%

Derma18%

Pain 5%

Vitamins 5%

Others10%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 82: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)

Cardiac 21.9 19.1 14.6 21.7 1.0

Ophthal 16.2 13.7 18.6 14.9 8.5

Derma 10.7 10.6 1.3 9.5 12.4

Pain 2.8 2.6 6.5 2.6 6.9

Vitamins 2.4 2.8 -16.6 2.4 -1.8

Neuro 1.3 1.1 16.2 1.2 14.6

Gastro Intestinal 1.2 1.3 -8.7 1.0 23.4

Anti-Infectives 1.1 0.9 17.4 1.2 -10.5

Anti Diabetic 1.2 0.8 57.5 1.2 3.2

Respiratory 0.3 0.3 -6.8 0.4 -29.3

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 271, 38.6%

Chronic, 354, 50.5%

Sub-Chronic, 76,

10.8%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

44%

11%9%

12%

24%

Top 10 11 to 20 21 to 30 31 to 50 Others

Source: AIOCD data base

Page 19: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 19

Alembic Pharmaceuticals

Stock Performance

406080

100120140160180200

May-16 Jul-16 Sep-16 Nov-16 Jan-17 Mar-17 May-17

CNX Pharma Alembic Pharma

Source: NSE, ICICIdirect.com Research

Exhibit 83: Company growth vis-à-vis Indian pharma market growth

5.9

10.2

8.2

11.4

17.7

13.7

9.2

15.5

7.6 10

.1

7.1 9.

6

8.3

5.4

11.8

11.6

17.9 20

.4

11.5

6.3

4.6

-2.1

-1.4

-2.7

1.4

5.1

-5

0

5

10

15

20

25Ap

r-16

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Indian Pharma Market Alembic

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 84: Market share in Indian formulations market

1.3 1.31.3

1.41.4

1.4 1.4

1.3 1.31.3

1.31.2 1.2

1.1

1.2

1.2

1.3

1.3

1.4

1.4

1.5

Apr-1

6

May

-16

Jun-

16

Jul-1

6

Aug-

16

Sep-

16

Oct-1

6

Nov

-16

Dec-

16

Jan-

17

Feb-

17

Mar

-17

Apr-1

7

(%)

Alembic

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 85: Top 10 brands performance (| crore)

Brand Therapy Apr' 17 Apr' 16 Var. (%) Mar' 17 Var. (%)Azithral Anti-Infectives 10.7 9.0 18.9 10.2 4.8

Althrocin Anti-Infectives 5.2 5.8 -9.9 5.3 -2.2

Gestofit Gynaecological 5.1 5.3 -3.8 4.7 8.6

Wikoryl Respiratory 3.7 3.1 18.2 4.4 -15.0

Roxid Anti-Infectives 3.6 4.3 -15.9 3.6 -0.8

Rekool D Gastro Intestinal 2.6 2.5 1.3 2.4 7.4

Ulgel Gastro Intestinal 2.3 2.8 -16.3 2.1 8.8

Glisen Mf Anti Diabetic 2.2 2.1 2.4 1.9 15.3

Richar Gynaecological 2.1 2.1 0.6 2.0 9.2

Tellzy Ch Cardiac 1.9 1.6 16.2 1.8 5.7

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 86: Contribution of therapies to domestic sales (MAT Apr’ 17) Anti-Infectives

22%

Cardiac15%Gastro

Intestinal13%

Respiratory13%

Gynaecological12%

Other25%

Source: AIOCD data base, ICICIdirect.com Research

Exhibit 87: Therapy wise performance (| crore)

Therapy Apr' 17 Apr' 16 YoY (%) Mar' 17 MoM (%)Anti-Infectives 23.4 22.5 4.1 23.1 1.3Cardiac 19.0 17.7 7.5 17.2 10.5Gastro Intestinal 15.2 15.7 -3.5 13.7 11.0Respiratory 12.2 11.2 9.1 13.6 -10.1Gynaecological 14.5 13.6 6.7 13.3 8.5Vitamins 10.1 9.9 2.0 8.5 18.9Anti Diabetic 9.7 7.9 23.0 8.7 10.9Pain 3.9 4.5 -12.5 3.4 15.6Urology 3.0 2.3 30.2 3.0 1.8Derma 1.9 2.1 -9.9 1.7 11.1

Source: AIOCD data base, ICICIdirect.com Research

Acute : Chronic contribution (| crore; MAT Apr’ 17)

Acute, 834,

56.4%

Chronic 231.46, 18.8%

Sub-Chronic 214.35, 17.4%

Source: AIOCD data base

Brands contribution to domestic sales (MAT Apr’ 17)

44%

11%9%

12%

24%

Top 10 11 to 20 21 to 30 31 to 50 Others

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ICICI Securities Ltd. | Retail Equity Research

Page 20

US Regulatory approvals

Exhibit 88: Summary of USFDA approvals for Apr, 2017 [5

Company Drug Name Therapeutic Area Innovator company Generic Version of Market SizeSun Pharma Tazarotene Derma Allergan Tazorac NAJubilant Lifesciences Celecoxib Anti-Inflammatory GD Searle Celebrex US$ 2.44 billionAlembic Pharma Fluoxetine Hydrochloride CNS APIL Sarafem NALupin Bupropion Hydrochloride Anti-depressant GSK Wellbutrin NAGlenmark Fenofibrate Tablets Anti-cholesterol Abbott Tricor NAAurobindo Simpesse Oral Contraceptive Teva Seasonique NAAurobindo Rocuronium Bromide Anathesia Merck Zemuron NAUnichem Piroxicam Pain Pfizer Feldene NASun Pharma Felbamate CNS Medpointe Pharm HLC Felbatol NATorrent Pharma Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionAlembic Pharma Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionAlembic Pharma Hct Olmesartan Medoxomil CVS Daiichi Sankyo Benicar HCT US$ 1.8 billionAurobindo Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionCadila Healthcare Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionAurobindo Hct Olmesartan Medoxomil CVS Daiichi Sankyo Benicar HCT US$ 1.8 billionJubilant Lifesciences Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionCadila Healthcare Cholestyramine Obesity BMS Questran NADr Reddys Labs Ezetimibe; Simvastatin Obesity Merck Vytorin NALupin Olmesartan Medoxomil CVS Daiichi Sankyo Benicar US$ 1.8 billionAurobindo Lo Simpesse Oral Contraceptive Teva Seasonique NA

Company Drug Name Therapeutic Area Innovator company Generic Version of Market SizeCipla Abacavir Sulfate;Lamivudine Tablets Anti-retroviral VIIV Healthcare Epzicom US$ 449 millionAlembic Pharma Vilazodone Hydrochloride CNS Merck Vilbryd NAGlenmark Pharma Dabigatran Etexilate CVS Boehringer Ingelheim Pradaxa NASun Pharma Doxycycline Anti-Infective Aqua Pharma Monodox US$ 181 millionBiocon Fingolimod multiple sclerosis Novartis Gilenya NA

Final Approvals

Tentative Approvals

Annexure Monthly Sector News M&As, demergers, tie-ups and JVs

Torrent Pharma acquires hormone segment brands in India from Novartis Torrent Pharma has acquired two leading women's healthcare brands - Regestrone and Pregachieve from Novartis in India. Jubilant Life acquires US based radiopharmacy business Jubilant Life has signed an asset purchase agreement with Triad Isotopes to acquire substantially all of the assets, which comprise the radiopharmacy business of Triad. Triad recorded revenues in excess of US$225 million in CY16 with positive EBITDA and operates the second largest radiopharmacy network in the US with more than 50 pharmacies. Price cuts, new launches, recalls, approvals

Natco launches cancer drug pomalidomide in India Natco has launched the generic version of Pomalidomide (oncology) capsules in India. The company will market generic pomalidomide capsules under its brand name Pomalid in India. The drug is sold under brand name Pomalyst by Celegene in the US. Natco Pharma launches hepatitis C drug Velpanat in India Natco Pharma has launched a hepatitis C fixed dose combination drug Sofosbuvir (400 mg) and Velpatasvir (100 mg) under the brand name of Velpanat in India. Velpanat is the generic version of Epclusa, manufactured by Gilead Sciences globally. Natco has signed a nonexclusive licensing agreement with Gilead Sciences, to manufacture and sell generic versions of its chronic hepatitis C medicines in 101 developing countries.

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Taro Pharma recalls Nystatin, Triamcinolone Acetonide cream in US Sun Pharma subsidiary Taro Pharma has recalled 278304 tubes of Nystatin and Triamcinolone Acetonide Cream (dermatology), due to failed content uniformity specifications. Jubilant Life recalls BuPROPion Hydrochloride ER Tablets in US Jubilant Lifesciences has received class III product recalls from US, namely, 121641 bottles of BuPROPion Hydrochloride Extended-release Tablets due to failed impurities/degradation specifications. Glenmark initiates clinical investigation for GBR 310 Glenmark's Investigational New Drug (IND) application for its proposed biosimilar GBR310 (respiratory) has been approved. GBR 310 will assess its pharmacokinetics in comparison to Xolair (omalizumab) in healthy adult volunteers between 18 and 65 years of age. The annual sales of Xolair were ~US$1.7 billion in the US (IMS MAT February 2017). Lupin launches erectile dysfunction drug Cialis Lupin has launched Cialis (tadalafil), an oral PDE5 inhibitor, for the treatment of erectile dysfunction (ED) in adult males in India. Lupin has acquired the rights to market, promote and distribute Lilly’s Erectile Dysfunction (ED) product, Cialis through its specialty field force while Lilly will be responsible for manufacturing and importing the product. The PDE-5 market in India is valued at ~| 390 crore, out of which Tadalafil contributes around 23%. The market size has doubled since 2012 and is growing annually at 15%. Glenmark gets US FDA clearance to begin phase 1 study of GBR 1342 USFDA has cleared Glenmark’s investigational new drug (IND) application to initiate a Phase 1 study of GBR 1342 (oncology), a humanised, bispecific monoclonal antibody (bsAb) being studied for the treatment of multiple myeloma in patients who have received prior therapies Lawsuits, court rulings, settlements, regulatory issues

US court rules in favour of Cadila in patent case of gLialda Cadila Healthcare has won a judgement against Shire Pharma, holding that its proposed generic version of Lialda (oncology) does not infringe the US patent. The drug had US sales of US$714 million (CY16). Biocon’s Bangalore facility receives eight observations from USFDA Biocon's manufacturing facility in Bangalore has received eight form 483 observations from USFDA. The company has already responded to USFDA on all observations within stipulated timelines. Lupin Aurangabad plant receives eight observations from USFDA Lupin's Aurangabad facility has received eight observations from the USFDA. The plant's inspection was carried out from April 17-26, 2017. Lupin Goa plant receives three observations from USFDA Lupin’s Goa plant has received three observations from USFDA. As per media sources, Lupin has received voluntary action indicated (VAI) status for Goa plant from USFDA. Dr Reddy’s Hyderabad plant receives 11 observations from USFDA Dr Reddy's Hyderabad (Bachupally) formulations manufacturing plant 3 has received 11 observations from USFDA. As per the managements, these observations are mostly procedural in nature, reflecting need to improve people capabilities and strengthen documentation and laboratory systems USFDA issues warning letter to Divis Labs for Vishakhapatnam unit Divis lab Vishakhapatnam unit 2 has been issued a warning letter by the USFDA. This plant is already under USFDA import alert and has been exempted from several manufactured products (12 products).

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Page 22

Aurobindo’s Unit 3 plant receives six observations from USFDA Aurobindo Pharma has received six observations at its Unit 3 oral formulations plant. As per the management, the observations are all procedural in nature. Jubilant Life receives | 50 lakh fine from NGT Jubilant Life has received a | 50 lakh fine from NGT on five units of Amroha for discharging untreated effluents in the open and extracting ground water beyond permissible limits. This plant has been ordered to be shut by NGT and respond with corrective action plan within a week, in a case relating to pollution of river Ganga and drainage canals leading to river Ganga. CCI rules in favour of Biocon in case against Roche over breast cancer drug Competition Commission of India (CCI) is investigating to ascertain whether Roche tried to block access to Biocon and Mylan biosimilars in India for its Trastuzumab (anti-cancer) drug. However, the order should not be construed as final opinion on the ongoing case. The order comes as a response to a joint complaint filed by the Mylan and Biocon in 2016 alleging that the Roche Group indulged in "abusive conduct”. Others

Lupin completes expansion of US manufacturing facility As per media sources, Lupin has expanded its Somerset, New Jersey manufacturing facility to 100,000-sq ft. The new facility will focus on making affordable medicines for treatment in various therapeutic areas. Jubilant Life raises | 100 crore Jubilant Life has issued commercial papers of | 100 crore on April 18, 2017. Q4FY17 Result Highlights

Ajanta Pharma - Upbeat numbers driven by Asia, US Revenues grew 12% YoY to | 477 crore on the back of 14% growth in domestic sales to | 140 crore and a sharp jump in US sales. EBITDA margins improved 82 bps YoY to 33.8% driven by 308 bps increase in gross margins to 80.7%. EBITDA increased 15% YoY to | 161 crore. Adjusted net profit increased 6% YoY to | 114 crore. Alembic Pharma - Q4 driven by exports, domestic specialty Revenues increased 18% YoY to | 741 crore on account of 54% YoY growth in the US to | 200 crore. Domestic formulations grew 10% YoY to | 286 crore driven by 13% growth in speciality portfolio. EBITDA margins contracted 471 bps YoY to 18.2% due to higher raw material and employee cost. EBITDA declined 6% YoY to | 135 crore. Net profit increased 2% YoY to | 93 crore mainly due to lower taxation. Biocon- Subdued Q4 Revenues declined 1.5% YoY to | 931 crore due to elongated approval timelines in emerging markets, discontinuance of in-licensed products and fire incident at Syngene. EBITDA margins contracted 70 bps YoY to 20.1% mainly due to higher raw material & employee cost. EBITDA declined 4.8% YoY to | 188 crore. Net profit increased 106% YoY to | 127.5 crore on account of higher other income. Dr Reddy’s Labs - US performance continues to weigh on numbers Revenues declined 5% YoY to | 3554 crore mainly due to a 19% decline in US sales to | 1535 crore led by increased competition in key products, coupled with discontinuation of McNeil contract. EBITDA margins declined 643 bps to 15.1% mainly due to sharp decline in gross margins by 549 bps to 51.2% led by one-offs. Adjusted net profit fell 40% YoY to | 338 crore mainly due to lower operational performance.

Page 23: US pricing pressure steeper than expected

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Page 23

Glenmark Pharma - Huge miss led by disappointing US show Revenues grew 8% YoY to | 2457 crore mainly due to 53.5% YoY growth in the US to | 1000 crore led by gZetia Exclusivity. Miss vis-à-vis ours and consensus estimate was due to lower US traction, which was way below expectation. EBITDA margins increased 481 bps YoY to 18.1%. The YoY increase is mainly attributable to the lower base margins in Q4FY16. EBITDA increased 46% YoY to | 444 crore. Adjusted net profit increased 23.5% YoY to | 184 crore but came in below I-direct estimate of | 693 crore. Syngene International - Lag effect of fire incident hurts topline Revenues declined 12% YoY to | 291 crore lower than I-direct estimates of | 385 crore. EBITDA margins contracted 95 bps to 34.5% YoY mainly due to higher raw material and employee cost. EBITDA declined 15% to | 100 crore. Net profit declined 1% to | 78 crore mainly due to a below estimated operational performance and higher other income.

Page 24: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 24

Exhibit 89: US Patent litigations [5

Month Innovator ANDA Filer Brand Name API Used for Nov-16 Onyx Therapeutics Dr Reddy's Lab Kyprolis carfilzomib multiple myelomaNov-16 Onyx Therapeutics Cadila Kyprolis carfilzomib multiple myelomaNov-16 Indoco Remedies Zydus Pharma Abilify Aripiprazole SchizophreniaNov-16 UCB Inc Cadila Neupro rotigotine ParkinsonNov-16 Amarin Pharma Dr Reddy's Lab Vascepa icosapent ethy hypertri- glyceridemiaNov-16 Medicis Pharma Dr Reddy's Lab Solodyn minocycline infectionsDec-16 Sanofi-Aventis Torrent Pharma AUBAGIO teriflunomide multiple sclerosisDec-16 AstraZeneca AB Cipla Nexium 24HR esomeprazole treatment of acid refluxDec-16 Sanofi-Aventis Glenmark AUBAGIO teriflunomide multiple sclerosisDec-16 Sanofi-Aventis Alembic Pharma AUBAGIO teriflunomide multiple sclerosisDec-16 Wyeth Pharma Alembic Pharma BOSULIF bosutinib leukemiaDec-16 Sanofi-Aventis Aurobindo AUBAGIO teriflunomide multiple sclerosisDec-16 Eli Lilly and Co., ICOS Corp. Ajanta Pharma CIALIS tadalafil erectile dysfunctionDec-16 Astellas Pharma Cadila XTANDI enzalutamide prostate cancerDec-16 Cephalon, Inc. Cipla Abraxane paclitaxel breast cancerJan-17 Sanofi-Aventis Biocon AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Teva Pharma AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis MSN Laboratories AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Hetero Labs AUBAGIO teriflunomide multiple sclerosisJan-17 Sanofi-Aventis Zydus Pharma (USA) AUBAGIO teriflunomide multiple sclerosisJan-17 AbbVie Inc Aurobindo Pharma KALETRA ritonavir HIVJan-17 Novartis AG Aurobindo Pharma GILENYA fingolimod multiple sclerosisJan-17 Novartis AG Aurobindo Pharma GILENYA fingolimod multiple sclerosisJan-17 Shionogi Inc Aurobindo Pharma FORTAMET metformin Type 2 diabetesJan-17 Dow Pharma Taro Pharma ONEXTON cindamycin phosphate, benzoyl peroxide AcneJan-17 Aptalis Pharma Zydus Pharma (USA) CANASA mesalamine Ulcerative proctitisFeb-17 Pfizer Inc Torrent Pharma TOVIAZ glatiramer acetate IncontinenceFeb-17 Biomarin Pharma Dr. Reddy's Lab KUVAN sapropterin PhenylketonuriaFeb-17 AstraZeneca AB Dr. Reddy's Lab FASLODEX fulvestrant Breast cancerFeb-17 iCeutica Pty Ltd Lupin Ltd VIVLODEX meloxicam Osteoarthritis painFeb-17 Pfizer Inc Sun Pharma XELJANZ XR tofacitinib citrate Rheumatoid arthritisMar-17 Pfizer Inc Cadila Healthcare XELJANZ XR tofacitinib citrate Rheumatoid arthritisMar-17 Dow Pharma Taro Pharma Onexton cindamycin phosphate, benzoyl peroxide AcneMar-17 Novartis, Mitsubishi Tanabe PharmAlembic GILENYA fingolimod multiple sclerosisMar-17 Teva Lupin PROAIR HFA albuterol sulfate RespiratoryMar-17 ViiV Healthcare;Vertex Pharma Lupin LEXIVA fosamprenavir HIVMar-17 Alcon Research Lupin PAZEO olopatadine ConjunctivitisApr-17 BMS ; Pfizer Aurobindo ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Lupin ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Torrent Pharma ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Unichem ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Dr. Reddy's Lab ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Indoco Remedies ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Sun Pharma ELIQUIS apixaban AnticoagulantApr-17 BMS ; Pfizer Cadila Healthcare ELIQUIS apixaban AnticoagulantApr-17 Celgene Corp Cadila Healthcare REVLIMID lenalidomide OncologyApr-17 Elli Lilly Dr. Reddy's Lab CIALIS tadalafil erectile dysfunctionApr-17 Millenium Pharma Cadila Healthcare REVLIMID lenalidomide OncologyApr-17 Bayer Pharma Taro Pharma Xarelto Rivaroxaban Blood ThinnerApr-17 Bayer Pharma Aurobindo Pharma Xarelto Rivaroxaban Blood Thinner

Source: Bloomberg, ICICIdirect.com Research

Page 25: US pricing pressure steeper than expected

ICICI Securities Ltd. | Retail Equity Research

Page 25

Exhibit 90: One year forward P/E of CNX Pharma vs. Nifty

05

1015202530354045

May

-12

Nov

-12

May

-13

Nov

-13

May

-14

Nov

-14

May

-15

Nov

-15

May

-16

Nov

-16

May

-17

x

CNX Pharma Nifty

11% Premium

[

Source: Company, ICICIdirect.com Research

ICICIdirect.com coverage universe (Healthcare) Company I-Direct CMP TP Rating M Cap

Code (|) (|) (| Cr) FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E FY16 FY17E FY18E FY19E

Ajanta Pharma AJAPHA 1664 1,880 Buy 14644.0 45.4 58.5 61.7 72.4 36.6 28.5 27.0 23.0 42.9 40.6 33.8 31.7 34.2 32.6 27.0 25.2

Alembic Pharma ALEMPHA 608 615 Hold 11459.9 38.2 21.4 23.4 30.2 15.9 28.4 26.0 20.2 51.5 26.1 22.3 24.7 44.9 21.4 20.0 21.8

Apollo Hospitals APOHOS 1303 1,440 Buy 18121.1 22.2 22.5 35.2 50.0 58.7 57.8 37.0 26.0 8.2 8.1 11.1 14.7 8.9 8.4 11.8 14.7

Aurobindo Pharma AURPHA 615 965 Buy 36005.4 33.9 38.7 39.5 49.1 18.1 15.9 15.6 12.5 23.3 23.6 20.9 22.6 28.1 24.6 20.3 20.5

Biocon BIOCON 994.3 1,020 Hold 19885.0 23.1 31.0 25.5 40.8 43.0 32.0 38.9 24.4 9.1 11.4 10.4 15.3 11.4 13.5 10.2 14.5

Cadila Healthcare CADHEA 484 425 Hold 49528.7 15.0 12.2 16.9 21.5 32.4 39.6 28.6 22.6 26.7 15.2 20.1 23.0 28.6 19.9 22.9 23.8Cipla CIPLA 561.9 575 Hold 45207.6 18.5 17.2 24.3 31.4 30.4 32.7 23.1 17.9 12.0 10.5 13.9 16.4 12.5 10.6 13.2 14.9

Divi's Lab DIVLAB 622 700 Hold 16500.2 41.8 41.1 42.8 47.8 14.9 15.1 14.5 13.0 30.7 26.8 24.4 23.7 25.9 21.6 19.3 18.6

Dr Reddy's Labs DRREDD 2706 2,610 Hold 44831.9 141.4 68.6 106.1 137.3 19.1 39.4 25.5 19.7 17.3 6.3 10.8 13.7 20.6 9.4 13.0 14.7

Glenmark Pharma GLEPHA 703 910 Buy 19849.1 32.2 46.9 47.9 50.5 21.8 15.0 14.7 13.9 16.2 20.6 19.8 19.1 21.2 25.9 21.2 18.4

Indoco Remedies INDREM 218.1 235 Hold 2009.3 9.4 8.7 12.7 15.6 23.2 25.0 17.1 14.0 12.9 9.5 13.9 16.1 14.8 12.4 15.8 16.8

Ipca Laboratories IPCLAB 547 560 Hold 6901.6 10.0 15.0 24.1 31.1 54.6 36.4 22.7 17.6 5.7 9.8 12.7 14.8 5.5 7.8 11.3 13.0

Jubilant Life JUBLIF 762.8 810 Buy 12149.2 26.0 37.0 51.1 68.0 29.3 20.6 14.9 11.2 12.0 14.1 15.6 18.5 14.2 17.1 19.4 20.7

Lupin LUPIN 1299 1,760 Buy 58669.8 50.4 61.7 67.2 83.6 25.8 21.0 19.3 15.5 18.6 20.2 20.8 23.9 20.7 20.9 19.2 19.9

Natco Pharma NATPHA 948.5 870 Buy 16533.1 8.5 25.3 14.8 18.2 111.8 37.5 64.3 52.2 16.0 33.0 17.6 19.2 11.9 27.2 14.0 15.0

Sun Pharma SUNPHA 647 765 Buy 155230.3 23.4 30.3 29.9 35.3 27.6 21.4 21.7 18.3 18.6 19.3 17.3 17.9 18.0 19.4 16.5 16.8

Syngene Int. SYNINT 484 515 Hold 9680.0 11.1 14.3 14.0 18.4 45.0 34.7 35.5 27.1 13.2 16.8 16.0 19.9 21.0 21.9 17.9 19.4

Torrent Pharma TORPHA 1340 1,475 Buy 22668.2 107.8 57.0 62.1 77.4 12.4 23.5 21.6 17.3 46.7 21.5 23.7 26.4 53.8 23.5 21.4 22.2

Unichem Lab UNILAB 264.1 285 Hold 2400.3 12.3 12.9 17.4 23.5 21.4 20.5 15.2 11.2 13.8 14.3 16.1 18.8 11.7 11.1 13.3 15.6

RoE (%)EPS (|) PE(x) RoCE (%)

Source: Company, ICICIdirect.com Research

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RATING RATIONALE ICICIdirect.com endeavours to provide objective opinions and recommendations. ICICIdirect.com assigns ratings to its stocks according to their notional target price vs. current market price and then categorises them as Strong Buy, Buy, Add, Reduce and Sell. The performance horizon is two years unless specified and the notional target price is defined as the analysts' valuation for a stock. Sector view: Over weight compared to index Equal weight compared to index Under weight compared to index Index here refers to BSE 500

Pankaj Pandey Head – Research [email protected]

ICICIdirect.com Research Desk, ICICI Securities Limited, 1st Floor, Akruti Trade Centre, Road No. 7, MIDC, Andheri (East) Mumbai – 400 093

[email protected]

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ICICI Securities Ltd. | Retail Equity Research

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ANALYST CERTIFICATION We /I, Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance), Harshal Mehta (MTech) Research Analysts, authors and the names subscribed to this report, hereby certify that all of the views expressed in this research report accurately reflect our views about the subject issuer(s) or securities. We also certify that no part of our compensation was, is, or will be directly or indirectly related to the specific recommendation(s) or view(s) in this report.

Terms & conditions and other disclosures: ICICI Securities Limited (ICICI Securities) is full-service, integrated investment banking and is, inter alia, engaged in the business of stock brokering and distribution of financial products. ICICI Securities Limited is a Sebi registered Research Analyst with Sebi Registration Number – INH000000990. ICICI Securities is a wholly-owned subsidiary of ICICI Bank which is India’s largest private sector bank and has its various subsidiaries engaged in businesses of housing finance, asset management, life insurance, general insurance, venture capital fund management, etc. (“associates”), the details in respect of which are available on www.icicibank.com. ICICI Securities is one of the leading merchant bankers/ underwriters of securities and participate in virtually all securities trading markets in India. We and our associates might have investment banking and other business relationship with a significant percentage of companies covered by our Investment Research Department. ICICI Securities generally prohibits its analysts, persons reporting to analysts and their relatives from maintaining a financial interest in the securities or derivatives of any companies that the analysts cover. The information and opinions in this report have been prepared by ICICI Securities and are subject to change without any notice. The report and information contained herein is strictly confidential and meant solely for the selected recipient and may not be altered in any way, transmitted to, copied or distributed, in part or in whole, to any other person or to the media or reproduced in any form, without prior written consent of ICICI Securities. While we would endeavour to update the information herein on a reasonable basis, ICICI Securities is under no obligation to update or keep the information current. Also, there may be regulatory, compliance or other reasons that may prevent ICICI Securities from doing so. Non-rated securities indicate that rating on a particular security has been suspended temporarily and such suspension is in compliance with applicable regulations and/or ICICI Securities policies, in circumstances where ICICI Securities might be acting in an advisory capacity to this company, or in certain other circumstances. This report is based on information obtained from public sources and sources believed to be reliable, but no independent verification has been made nor is its accuracy or completeness guaranteed. This report and information herein is solely for informational purpose and shall not be used or considered as an offer document or solicitation of offer to buy or sell or subscribe for securities or other financial instruments. Though disseminated to all the customers simultaneously, not all customers may receive this report at the same time. ICICI Securities will not treat recipients as customers by virtue of their receiving this report. Nothing in this report constitutes investment, legal, accounting and tax advice or a representation that any investment or strategy is suitable or appropriate to your specific circumstances. The securities discussed and opinions expressed in this report may not be suitable for all investors, who must make their own investment decisions, based on their own investment objectives, financial positions and needs of specific recipient. This may not be taken in substitution for the exercise of independent judgment by any recipient. The recipient should independently evaluate the investment risks. The value and return on investment may vary because of changes in interest rates, foreign exchange rates or any other reason. ICICI Securities accepts no liabilities whatsoever for any loss or damage of any kind arising out of the use of this report. Past performance is not necessarily a guide to future performance. Investors are advised to see Risk Disclosure Document to understand the risks associated before investing in the securities markets. Actual results may differ materially from those set forth in projections. Forward-looking statements are not predictions and may be subject to change without notice. ICICI Securities or its associates might have managed or co-managed public offering of securities for the subject company or might have been mandated by the subject company for any other assignment in the past twelve months. ICICI Securities or its associates might have received any compensation from the companies mentioned in the report during the period preceding twelve months from the date of this report for services in respect of managing or co-managing public offerings, corporate finance, investment banking or merchant banking, brokerage services or other advisory service in a merger or specific transaction. ICICI Securities or its associates might have received any compensation for products or services other than investment banking or merchant banking or brokerage services from the companies mentioned in the report in the past twelve months. ICICI Securities encourages independence in research report preparation and strives to minimize conflict in preparation of research report. ICICI Securities or its associates or its analysts did not receive any compensation or other benefits from the companies mentioned in the report or third party in connection with preparation of the research report. Accordingly, neither ICICI Securities nor Research Analysts and their relatives have any material conflict of interest at the time of publication of this report. It is confirmed that Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance), Harshal Mehta (MTech) Research Analysts of this report have not received any compensation from the companies mentioned in the report in the preceding twelve months. Compensation of our Research Analysts is not based on any specific merchant banking, investment banking or brokerage service transactions. ICICI Securities or its subsidiaries collectively or Research Analysts or their relatives do not own 1% or more of the equity securities of the Company mentioned in the report as of the last day of the month preceding the publication of the research report. Since associates of ICICI Securities are engaged in various financial service businesses, they might have financial interests or beneficial ownership in various companies including the subject company/companies mentioned in this report. It is confirmed that Siddhant Khandekar CA-INTER, Mitesh Shah MS (Finance), Harshal Mehta (MTech) Research Analysts do not serve as an officer, director or employee of the companies mentioned in the report. ICICI Securities may have issued other reports that are inconsistent with and reach different conclusion from the information presented in this report. Neither the Research Analysts nor ICICI Securities have been engaged in market making activity for the companies mentioned in the report. We submit that no material disciplinary action has been taken on ICICI Securities by any Regulatory Authority impacting Equity Research Analysis activities. This report is not directed or intended for distribution to, or use by, any person or entity who is a citizen or resident of or located in any locality, state, country or other jurisdiction, where such distribution, publication, availability or use would be contrary to law, regulation or which would subject ICICI Securities and affiliates to any registration or licensing requirement within such jurisdiction. The securities described herein may or may not be eligible for sale in all jurisdictions or to certain category of investors. Persons in whose possession this document may come are required to inform themselves of and to observe such restriction. report and information herein is solely for informational purpose and shall not be used or considered as an offer document or solicitation of offer to buy or sell or subscribe for securities or other financial instruments. Though disseminated to all the customers simultaneously, not all customers may receive this report at the same time. ICICI Securities will not treat recipients as customers by virtue of their receiving this report. Nothing in this report constitutes investment, legal, accounting and tax advice or a representation that any investment or strategy is suitable or appropriate to your specific circumstances. The securities discussed and opinions expressed in this report may not be suitable for all investors, who must make their own investment decisions, based on their own investment objectives, financial positions and needs of specific recipient. This may not be taken in substitution for the exercise of independent judgment by any recipient. The recipient should independently evaluate the investment risks. The value and return on investment may vary because of changes in interest rates, foreign exchange rates or any other reason. ICICI Securities accepts no liabilities whatsoever for any loss or damage of any kind arising out of the use of this report. Past performance is not necessarily a guide to future performance. Investors are advised to see Risk Disclosure Document to understand the risks associated before investing in the securities markets. Actual results may differ materially from those set forth in projections. Forward-looking statements are not predictions and may be subject to change without notice. ICICI Securities or its associates might have managed or co-managed public offering of securities for the subject company or might have been mandated by the subject company for any other assignment in the past twelve months. ICICI Securities or its associates might have received any compensation from the companies mentioned in the report during the period preceding twelve months from the date of this report for services in respect of managing or co-managing public offerings, corporate finance, investment banking or merchant banking, brokerage services or other advisory service in a merger or specific transaction. ICICI Securities or its associates might have received any compensation for products or services other than investment banking or merchant banking or brokerage services from the companies mentioned in the report in the past twelve months. ICICI Securities encourages independence in research report preparation and strives to minimize conflict in preparation of research report. ICICI Securities or its analysts did not receive any compensation or other benefits from the companies mentioned in the report or third party in connection with preparation of the research report. Accordingly, neither ICICI Securities nor Research Analysts have any material conflict of interest at the time of publication of this report. It is confirmed that Siddhant Khandekar CA-INTER Mitesh Shah MS (Finance), Harshal Mehta (MTech) Research Analysts of this report have not received any compensation from the companies mentioned in the report in the preceding twelve months. Compensation of our Research Analysts is not based on any specific merchant banking, investment banking or brokerage service transactions.