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Catalytic enantioselective synthesis of cyclopropanes featuring vicinal all-carbon quaternary stereocenters with a CH2F group; study of influence of C-F···H-N
interactions on reactivity
Zhong-Yan Cao,‡a Wenmin Wang,‡b Kui Liao,a Xiaoming Wang,d Jian Zhou*a,c,d and Jing Ma*b
aShanghai Key Laboratory of Green Chemistry and Chemical Process, East China Normal University, 3663N Zhongshan Road, Shanghai 200062, P. R. China. E-mail: [email protected]. bInstitute of Theoretical and Computational Chemistry, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, P R China. E-mail: [email protected]. cShanghai Engineering Research Center of Molecular Therapeutics and New Drug Development, East China Normal University, 3663N Zhongshan Road, Shanghai 200062, P. R. China. dState Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P R China. ‡These authors contributed equally to this article.
Supporting Information (Part C)
HPLC Spectra of 3a-3q, 4, 7a-7e 2-24
Electronic Supplementary Material (ESI) for Organic Chemistry Frontiers.This journal is © the Partner Organisations 2018
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2
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3
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4
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5
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6
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7
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8
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9
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10
NNHH
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CCll
CCll
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ClCl
ClCl
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11
NNHH
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BBrr
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33jj
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12
NNHH
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13
NNHH
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33ll
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14
NNHH
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15
NNHH
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16
NNHH
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17
NNHH
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OOMMee
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18
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19
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FFHH22CC CCOOOOMMee
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FFHH22CC CCOOOOMMee
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22
FFHH22CC CCOOOOMMee
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23
FFHH22CC CCOOOOMMee
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24
FF22HHCC CCOOOOMMee
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