urine characteristics & urinalysis

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    CHARACTERISTICS OF URINE

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    Urinalysis

    1. Physical characteristics: color, odor,turbidity, volume, & specific gravity

    2. Chemical characteristics: pH, glucose,protein, ketones, pus (WBCs &bacteria), RBCs, hemoglobin, bile . . .

    3. Microscopic exam of urine sediment:crystals, cells, etc.

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    Why is urinalysis an important

    part of routine patient exams? Urine contains important metabolic

    information & the presence of abnormalsubstances is helpful in diseasediagnosis

    Urine is cheap, simple, & readilyavailable

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    List the three main inorganic

    solutes of urine Sodium, potassium, & chloride

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    State the average daily urine

    output

    1200 - 1500 mL (1.2 - 1.5 L)

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    State the normal daily range

    of urine output 600 - 2000 mL (0.6 - 2.0 L)

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    Define the following terms:

    Anuria - complete stoppage of urine

    Oliguria - reduced amount of urine

    Polyuria - increased amount of urine

    Nocturia - increased amount of urine @night

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    Describe the different types ofurine specimens used in a

    medical lab

    Random 1st morning Mid-stream clean catch (MSCC) Fasting 24 hour

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    List the normal colors of urine

    Any shade of yellow due to the pigmenturochrome: light yellow, yellow, darkyellow, amber . . .

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    List abnormal colors of urine

    & possible causes Colorless - XS fluid intake; diabetes Orange - bilirubin, XS Vitamin A Green - bile, Pseudomonas bacteria Red/Brown - hemoglobin, beets

    Black - melanins Any abnormal color can be due to dyes,foods, or medications

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    State the term used to describeurine appearance

    Turbidity - cloudiness due toparticulate mattersuspended in urine

    Clear, transparent, hazy, cloudy,turbid, milky, or 0 - 4+ system

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    Identify several factors thatmay affect urine appearance

    Crystals, WBCs, RBCs, bacteria,epithelial cells, lipids, mucus, fecalmaterial, semen, lymph fluid, yeast,powders, creams, cotton fibers, etc.

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    Define specificgravity

    Density of a substancecompared to an equal

    volume of water at asimilar temperature

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    Describe a urinometer & theprocedure for using it todetermine s.g. of urine

    A device that displaces water and sinks

    to a level indicative of the specificgravity

    Pour urine in jar, place urinometer influid, spin & when it settles, read theresults

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    State the normal range ofspecific gravity for human

    urine

    1.001 - 1.035

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    Explain the significance of aspecific gravity of 1.023 -

    1.035 Normal; 1.023 or above indicates good

    kidney function

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    List 4 common reasons forabnormally high specific

    gravity results

    Presence of glucose Presence of protein Recent X-ray exposure

    Use of IVs Dehydrating illnesses - fever, sweat,vomit, diarrhea

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    List possible reasons forabnormally low specific gravity

    results

    Diabetes insipidus (water diabetes) Renal (kidney) disease/damage

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    Chemical Tests for Urine - pH Average Range: 4.5 - 8.0 Average: 6.0 Affected by diet & changes in body metabolism

    Acidic urine: -high protein diet or lots of

    whole wheat = acid formingfoods

    -diabetes

    Alkaline urine: -high veggie or dairy diet = baseforming foods

    -UTI

    Either: medications, kidney stones (renal calculi)

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    Chemical Tests for Urine -Glucose (glycosuria)

    Benign: -heavy meal-emotional stress

    Pathologic: -diabetes mellitus-kidney tubule defects

    -CNS damage-thyroid disorders

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    Chemical Tests for Urine -Protein (proteinuria)

    Benign: -cold-strenuous exercise-acute illness (fever)-orthostatic proteinuria

    Pathologic: -*kidney damage*

    -pre-eclampsia-hypertension-multiple myeloma

    Ch i l T f U i P

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    Chemical Tests for Urine - Pus(Pyuria)

    UTI (Urinary Tract Infection) orcontaminated specimen

    High Risk for UTI:-School age children esp. girls-pregnant women-diabetic people-previous history of UTIs -patients with catheters-elderly people

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    Chemical Tests for Urine -RBCs (Hematuria)

    Whole blood = cloudy red

    Bleeding in the urinary tract-trauma (ex: auto accident, kick)-kidney stones (renal calculi)

    -kidney infection (pyelonephritis)-tumors-toxic chemicals/drugs

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    Chemical Tests for Urine -Hemoglobin (hemoglobinuria)

    Hemoglobin = clear, red appearance

    -hemolytic anemia-transfusion reactions

    -severe burns

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    Chemical Tests for Urine - Bile

    (bilirubinuria)-hepatitis/liver disease

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    Chemical Tests for Urine -Ketones (ketonuria)

    Source: breakdown of fats instead ofcarbohydrates for energy

    -diabetes-starvation (decreased carbohydrate

    intake or increase carbohydrate loss -vomiting)

    -wrong dose of insulin

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    End.

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