urinary tract infection in the elderly

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    Urinary Tract Infection in the

    Elderly

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    Risk factors in Elderly

    medications:

    AH, AntiCh, Anti psychotic, analgeticsdecreasedparasympathetic toneurinary flow decrease, fecalimpactionurinary retention, post void volume incrbacterial colonisation

    Behavioral : incontinencepoor hygiene

    Physiological : voiding dysfunction (incontinence,increased residual volume, poor hygiene)

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    UTI in...

    Elderly

    Walking well

    With chronicdisease

    Institutionalized

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    UTI in the Walking Well ElderlyUTI Sign and Symptoms

    Urethritis Dysuria, purulent dischargeBacterial Prostatitis Dysuria, frequency,

    Suprapubic, pelvic, perineal pain

    Fever, malaise

    Reccurence rate >50% in

    elderly (acute)

    Chronic (symptoms > 3mos)

    Cystitis Dysuria, urgency, frequency,, F > MF : Poor hygiene

    M :Urinary retention (BPH,

    bladder enervation)

    FR:

    DM, Dementia, pelvicrelaxation syndrome

    Interstitial Cystitis

    (painful bladder

    syndrome)

    Pelvic pain, urgency, frequency,

    without bacteriuria

    e/: hormonal ,

    radiotherapyaltering

    mucosal lining

    Honeymoon cystitis ysuria, urgency, frequency,, Folllowing sexua, intercpourse

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    UTIs Secondary to Chronic Disease

    Due to

    Diabetes Mellitus Elderly with DM : 5x increased UTI risk

    Asymptomatic bacteriuria + DM needs

    special assessment ( risk on UTI in

    18months)

    Patophysiology

    Glycosuriaincreased adherence

    of bacteria

    Decreased neutrophils function

    Pyelonephritis Ascending from lower UTI Fever, nausea, vomiting,

    abdominal pain, Flank

    pain,

    Renal calculi Stoneobstructionstasisinfection

    struvite stone

    Hyperuricemia, hypercalcemia

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    UTI in Institutionalized Elderly

    12-30%

    increased perineal

    colonization, vaginitis, andbacterial colonization in

    the bladder.

    BPH tendency

    Difficult to assesssymptoms

    Often complicated byunderlying or chronic

    disease

    less able to excrete acidand ureafail tomaintain normal

    osmolality.

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    Additional risk factor:

    Decreased cognition + incontinence

    bedwetting or soiling, skin breakdown, secondary

    infectionplacement of a permanent urinary catheterrisk of urosepsis (bacteremia with systemic infection

    and potential vascular collapse).

    Urinary catheterization

    medications

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    Asymptomatic Bacteriuria

    50% institutionalizedelderly

    almost 100% incatheterized pt.

    >100,000 CFU/mlwithout symptoms or

    signs

    Benign, transient,and does not require

    AB.

    Some resolvespontaneously, somebecome symptomatic

    Therapy is provenineffective in

    reducing morbidityand mortality rate.

    Screen beforegenitourinary

    procedure,

    If +Levofloxacin500mg SD PO

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    DIAGNOSING UTI in ELDERLY

    UTI criteria for elderly still lacks of agreement

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    Diagnosis

    history

    Burning sensation when voiding, frequency, urgency, bed wetting, fall, fatigue

    Difficult to assess due to symptoms overlap, decreased cognitive

    PhysicalExamination

    Appears ill and distressed Fever or hypothermia might be slight/non

    Suprapubic, CVA tenderness, Urethral discharge

    Gynecologic exam :Organ prolapse, BPH

    lab

    UA: proteinuria, RBC, WBC > 10/HRF, nitrit

    CBC : leukocytosis

    Culture if no progress after 2 days pharmacotherapy

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    Culture results

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    therapy

    Walking well patients:

    1stline: Sulfonamid or ampicilin (3d)

    2ndline : kuinolon

    Prostitis

    Acute : kuinolon, sulfa (4-6wk)

    Chronic : culutre and sensitivity testAB 12wk

    Asymptomatic bacteriuria/funguriano th/

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    Conclusion

    Various geriatric populations are affected by UTIs.

    Each of these populations is impacted in different

    ways and requires a different treatment

    approach.

    Symptoms of UTI in elderly patients may differ

    from general population

    The treatment must be based on the patient'soverall health, underlying chronic conditions, and

    ability to care for himself or herself.

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    Thankyou