Uppsala Longitudinal Uppsala Longitudinal Study of Adult Men Study of Adult Men (ULSAM)(ULSAM)

Age 501970 - 1973

N = 2322

Age 601980 - 1985

N = 1860

Age 701991 - 1995

N = 1221

Age 771997 - 2001

N = 839

Age 882008 - 2009

N = 354

Age 822003 - 2005

N = 530

2011-02-15

ParticipationParticipation

0.0

0.1

0.2

0.3

0.4

0.5

0.6

0.7

0.8

0.9

1.0

Cum

ulat

ive

Pro

porti

on S

urvi

ving

2011-02-15

Causes of deathCauses of deathBy October 2010, 576 participants still were alive1746 participants have dead

2011-02-15

Hospital visitsHospital visits74 individuals have never been at the hospital46% off them are still alive

26% died over age of 65From remaining 2248 participants only 24%

are still aliveThey all together have visited hospital more

than 23 000 times and have spent there over 200 000 days

2011-02-15

Use of hospital time 1970-Use of hospital time 1970-20092009 Total 218 847 daysTotal 218 847 days

2011-02-15

MeasurementsMeasurements

2011-02-15

Genetic AnalysesGenetic AnalysesFirst genetic study published in 1997Over 4000 individual SNPs genotyped

2003 - 2010 In 2010 1221 individuals were genotyped

for ~180 000 SNPs using MetaboChip In 2010 110 individuals were genotyped

using Illumina 1M chip

2011-02-15

Research activityResearch activityAt least 50 researchers have been working

with ULSAM data under last three yearsOver 150 research proposals have been

approved by ICTUS group from 2002At least 220 articles have been published

from ULSAM initiation in 197027 doctoral theses have been defended

2011-02-15

Articles and theses based on Articles and theses based on ULSAM cohortULSAM cohort

2011-02-15