Update on the global status of implementation of preventive

chemotherapy (PC)

22 October 2020

Department of Control of Neglected Tropical Diseases (NTD)

World Health Organization, Geneva, Switzerland

Number of individuals received Preventive Chemotherapy (PC) interventions for at least one disease, 2010-2019, as of 22 October 2020

These interventions have been delivered to individuals living in areas which require PC and also in areas which may not require PC.

710 727808 792

857

9911034

11351190

1126

0

200

400

600

800

1000

1200

1400

2010 2011 2012 2013 2014 2015 2016 2017 2018 2019

Num

ber o

f ind

ivid

uals

(Mill

ions

)

Global status of preventive chemotherapy in 2019, as of 22 October 2020

PC implementation LF ONCHOSTH SCH

TRA PC6

PreSAC SAC SAC Adults

Number of countries requiring PC1 50 30 92 51 37 105

Number of people requiring PC 858.3M 217.9M 299.6M 745.8M 126.3M 108.4M 166.6M 1742M

Number of countries implemented and reported 38 25 35 56 33 17 27 74

Proportion (%) of districts implemented PC2 69.9 88.8 ND 62.6 40.0 16.1 61.3 ND

Proportion (%) of districts achieving effective coverage3 89.2 89.1 ND 68.6 82.8 47.6 81.2 ND

Number of people treated4 538.1M 136.8M 110.3M 431.2M 74.9M 15.5M 95.2M 1094M

Coverage (%)5 62.7 62.8 36.8 57.8 59.3 14.3 57.2 62.7

1 Number of endemic countries moved to post-treatment surveillance stage is not included in total.2 Proportion of known endemic districts implementing PC in countries that reported on PC interventions. 3 Proportion of districts implementing PC achieving the defined effective coverage for the disease >65% for LF and ONCHO, >75% for STH and SCH, and >80% for TRA.4 Number of people received treatment in areas where PC is required according to the recommended strategy for a specific disease. 5 Coverage is calculated as the number of people treated out of total population requiring PC. 6 For calculation of PC coverage for at least one disease TRA data is included starting from 2015.

LF – lymphatic filariasis; ONCHO – onchocerciasis; STH – soil-transmitted helminthiases; SCH – schistosomiasis; TRA – trachomaPreSAC – preschool-aged children (1–4 years); SAC – school-aged children (5–14 years); Adults – people aged >15 years Source: WHO/NTD

77.169.5

46.3

63.0 65.857.2

0

10

20

30

40

50

60

70

80

90

LF ONCHO STH SCH TRA PC

Cove

rage

(%)

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

PC implementation AFR AMR EMR SEAR WPR GLOBAL

Number of countries requiring PC1 32 2 1 5 10 50

Number of people requiring PC 339.3M 6.6M 10.9M 492.9M 8.7M 858.3M

Number of countries implemented and reported2 24 2 1 4 7 38

Proportion (%) of districts implemented PC3 66.1 69.0 70.5 92.8 51.2 69.9

Proportion (%) of districts achieving effective coverage4 90.1 85.0 32.6 94.3 90.5 89.2

Number of people treated 180.8M 1.7M 4.4M 348.7M 2.5M 538.1M

Coverage (%)5 53.3 25.5 40.6 70.8 28.7 62.7

72.562.3

72.463.4 63.0

40.6

0

10

20

30

40

50

60

70

80

AFR AMR EMR SEAR WPR GLOBAL

Cove

rage

(%)

200820092010201120122013201420152016201720182019

Global status of preventive chemotherapy in 2019 – lymphatic filariasis

AFR – African Region; AMR – Region of the Americas; EMR – Eastern Mediterranean Region; SEAR – South-East Asia Region; WPR – Western Pacific Region Source: WHO/NTD

1 Number of endemic countries moved to post-treatment surveillance stage is not included in total.2 Number of countries reporting data on PC implementation. Countries submitting blank reports are not included in total.3 Proportion of known endemic districts implementing PC in countries that reported on PC interventions. 4 Proportion of districts implementing PC achieving the defined effective coverage for the disease - >65% for LF.5 Coverage is calculated as the number of people treated out of total population requiring PC.

78.3 77.177.089.2

0

10

20

30

40

50

60

70

80

90

100

AFR AMR EMR GLOBAL

Cove

rage

(%)

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

AFR – African Region; AMR – Region of the Americas; EMR – Eastern Mediterranean Region. Source: WHO/NTD

PC implementation AFR AMR EMR GLOBAL

Number of countries requiring PC1 26 2 2 30

Number of people requiring PC 217.2M 34K 0.685M 217.9M

Number of countries implemented and reported2 21 2 2 25

Proportion (%) of districts implemented PC3 88.6 100 100 88.8

Proportion (%) of districts achieving effective coverage4 88.9 100 100 89.1

Number of people treated 136.1M 26K 0.611M 136.8M

Coverage (%)5 62.7 77.0 89.2 62.8

Global status of preventive chemotherapy in 2019 – onchocerciasis

1 Number of endemic countries moved to post-treatment surveillance stage is not included in total.2 Number of countries reporting data on PC implementation. Countries submitting blank reports are not included in total.3 Proportion of known endemic districts implementing PC in countries that reported on PC interventions. 4 Proportion of districts implementing PC achieving the defined effective coverage for the disease - >65% for ONCHO.5 Coverage is calculated as the number of people and treated out of total population requiring PC.

66.7

39.5 44.5

86.2

69.561.5 61.3

0102030405060708090

100

AFR AMR EMR EUR SEAR WPR GLOBAL

Cove

rage

(%)

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

36.8

57.8

0

20

40

60

80

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

Cove

rage

(%)

Pre-SAC SAC

Global status of preventive chemotherapy in 2019 – soil-transmitted helminthiasesPreschool-aged children (1–4 years) AFR AMR EMR EUR SEAR WPR GLOBAL

Number of countries requiring PC1 40 19 8 4 8 13 92

Number of people requiring PC 89.9M 17.2M 20.1M 2.5M 151.6M 18.3M 299.6M

Number of countries implemented and reported2 15 5 0 0 6 9 35

Number of people in need and treated5 11.9M 0.7M 0 0 87M 10.7M 110.3M

Coverage (%)6 13.3 3.8 0 0 57.4 58.8 36.8

School-aged children (5–14 years) AFR AMR EMR EUR SEAR WPR GLOBAL

Number of countries requiring PC1 40 19 8 4 8 13 92

Number of people requiring PC 177.8M 40.3M 39.5M 3.9M 438.2M 46.1M 745.8M

Number of countries implemented and reported2 27 6 4 2 8 9 56

Proportion (%) of districts implemented PC3 57.8 38.5 22.2 5.8 93.8 79.6 62.6

Proportion (%) of districts achieving effective coverage4 78.7 58.7 38.7 41.7 57.6 69.3 68.6

Number of people in need and treated5 88M 5.3M 12.8M 2.4M 294M 28.7M 431.2M

Coverage (%)6 49.5 13.1 32.5 60.2 67.1 62.4 57.8

Source: WHO/NTDAFR – African Region; AMR – Region of the Americas; EMR – Eastern Mediterranean Region; EUR – European Region; SEAR – South-East Asia Region; WPR – Western Pacific Region

1.8

45.5

62.5

46.3

59.2

88.1

0102030405060708090

100

AFR AMR EMR SEAR WPR GLOBAL

Cove

rage

(%)

2008

2009

2010

2011

2012

2013

2014

2015

2016

2017

2018

2019

Regional coverage is calculated starting from 2010 when new country estimates by age group were published

Global status of preventive chemotherapy in 2019 – schistosomiasis

PC implementation AFRSAC/Adults

AMRSAC

EMRSAC/Adults

SEARSAC/Adults

WPRSAC/Adults

GLOBALSAC/Adults

Number of countries requiring PC1 41 2 4 1 3 51

Number of people requiring PC 112.1M/98.5M 1.6M/6K 11.5M/8M 6K/16K 1.1M/1.9M 126.3M/108.4M

Number of countries implemented and reported2 28/12 0 1/1 1/1 3/3 33/17

Proportion (%) of districts implemented PC3 41.6/14.4 0 18.9/25.4 100 100 40.0/16.1

Proportion (%) of districts achieving effective coverage4 86.2/52.3 0 29.6/8.8 100 37.5/34.4 82.8/47.6

Number of people treated 71.8M/13.8M 0 2.5M/0.6M 4K/15K 0.6M/1.1M 74.9M/15.5M

Coverage (%)5 64/14 0 21.6/7.2 70.7/94.4 57.8/57.8 59.3/14.3

AFR – African Region; AMR – Region of the Americas; EMR – Eastern Mediterranean Region; SEAR – South-East Asia Region; WPR – Western Pacific Region Source: WHO/NTD

1 Number of endemic countries moved to post-treatment surveillance stage is not included in total.2 Number of countries reporting data on PC implementation. Countries submitting blank reports are not included in total.3 Proportion of known endemic districts implementing PC for SAC in countries that reported on PC interventions. 4 Proportion of districts implementing PC achieving the defined effective coverage of SAC population for the disease - >75% for SCH.5 Coverage is calculated as the number of people in need of PC and treated out of total population requiring PC.

59.3

14.3

01020304050607080

2011

2012

2013

2014

2015

2016

2017

2018

2019

Cove

rage

(%)

SAC Adults

77.5

10.05.5

37.3

64.257.2

0

10

20

30

40

50

60

70

80

90

AFR AMR EMR SEAR WPR GLOBAL

Cove

rage

(%)

2014

2015

2016

2017

2018

2019

AFR – African Region; AMR – Region of the Americas; EMR – Eastern Mediterranean Region; SEAR – South-East Asia Region; WPR – Western Pacific Region Source: WHO/NTD

PC implementation AFR AMR EMR SEAR WPR GLOBAL

Number of countries requiring PC1 21 3 5 0 8 37

Number of people requiring PC 144.6M 5.2M 13M 0 3.8M 166.6M

Number of countries implemented and reported2 16 3 3 2 3 27

Number of people treated 92.8 0.001 2.3 0.001 0.134 95.2M

Coverage (%)3 64.2 <0.1 17.4 0 3.5 57.2

Global status of preventive chemotherapy in 2019 – trachoma

1 Number of endemic countries moved to post-treatment surveillance stage is not included in total.2 Number of countries reporting data on PC implementation. Countries submitting blank reports are not included in total.3 Coverage is calculated as the number of people and treated out of total population requiring PC.