UK Renal Registry 9th Annual Report 2006

Fig 13.1 ERF patients below 15 years of age, by year of data collection

250

300

350

400

450

500

550

600

1986 1988 1990 1992 1994 1996 1998 2000 2002 2004 2006

Year

Pat

ient

s

UK Renal Registry 9th Annual Report 2006

Fig 13.2 ERF population in 4 year age bands

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

2002 2003 2004 2005

Year

Per

cent

age

of p

atie

nts

16 - 19.99

12 - 15.99

8 - 11.99

4 - 7.99

0 - 3.99

UK Renal Registry 9th Annual Report 2006

Fig 13.3 Gender distribution of the ERF population, according to age

0%10%20%30%40%50%60%70%80%90%

100%

0 - 3 4 - 7 8 - 11 12 - 15 16 - 19

Age group (yrs)

Gen

der

dist

ribut

ion

Females

Males

UK Renal Registry 9th Annual Report 2006

Fig 13.4 Age distribution of the White and Ethnic minority patients

0%

20%

40%

60%

80%

100%

0 - 3 4 - 7 8 - 11 12 - 15 16 - 19

Age group (yrs)

Per

cent

age

of p

atie

nts

Ethnic minority

White

UK Renal Registry 9th Annual Report 2006

Figure 5. Gender distribution and ethnicity in the paediatric population

0

10

20

30

40

50

60

70

80

90

100

0 - 3 4 - 7 8 - 11 12 - 15 16 - 19

Age group (yrs)

Mal

es, a

s a

perc

enta

ge

of th

e po

pula

tion

White

South Asian

UK Renal Registry 9th Annual Report 2006

Fig 13.6 Prevalence of ERF according to gender

0

20

40

60

80

100

120

0 - 3 4 - 7 8 - 11 12 - 15 16 - 19

Age group (yrs)

Pre

vale

nce

(pm

p)

Males

Females

UK Renal Registry 9th Annual Report 2006

Fig 13.7 Prevalence of ERF according to ethnicity.

0

15

30

45

60

75

90

105

120

135

150

White South Asian Black Other

Ethnicity

Pre

vale

nce

(p

mp

)

UK Renal Registry 9th Annual Report 2006

Fig 13.8 Take on rate of children with ERF according to gender

0

2

4

6

8

10

12

0 - 3 4 - 7 8 - 11 12 - 15

Age group (yrs)

Tak

e on

rat

e (p

mp)

Males

Females

UK Renal Registry 9th Annual Report 2006

Fig 13.9 Take on rate of children with ERF according to ethnicity

UK Renal Registry 9th Annual Report 2006

Figure 10. Gender distribution of the ERF population, according to diagnostic group

0% 20% 40% 60% 80% 100%

Dysplasia

Glomerular

Obstructive

Interstitial

Reflux

CNS

Metabolic

Renovascular

Uncertain

PKD

Drug toxicity

MalignancyD

iagn

ostic

gro

upin

g

Percentage

Males

Females

UK Renal Registry 9th Annual Report 2006

Fig 13.11 Percentage of inherited disease, according to ethnicity

0%

10%

20%

30%

40%

50%

60%

70%

80%

90%

100%

White South Asian Black Other

Ethnicity

Non-inherited

Inherited

UK Renal Registry 9th Annual Report 2006

Fig 13.12(a) Percentage of patients with renal dysplasia, obstructive uropathy, glomerular diseases and reflux nephropathy presenting in

each age band

0

10

20

30

40

50

60

0 - 3 4 - 7 8 - 11 12 - 15Age group (yrs)

Per

cent

age

of p

atie

nts

Dysplasia

Obstuctive

Glomerular

Reflux

UK Renal Registry 9th Annual Report 2006

Fig 13.12(b) Percentage of patients presenting in each age band with renal dysplasia

0

5

10

15

20

25

30

35

40

0 - 3 4 - 7 8 - 11 12 - 15Age group (yrs)

Pe

rce

nta

ge

of p

atie

nts

Dysplasia

Obstuctive

Glomerular

Reflux

UK Renal Registry 9th Annual Report 2006

Fig 13.13(a) Percentage of patients with tubulo-interstitial diseases, metabolic diseases, congenital nephrosis and polycystic disease

presenting in each age band

0

10

20

30

40

50

60

70

0 - 3 4 - 7 8 - 11 12 - 15Age group (yrs)

Per

cent

age

of p

atie

nts

Tubular/Interstitial

Metabolic

CNS

PKD

UK Renal Registry 9th Annual Report 2006

Fig 13.13(b) Percentage of patients presenting in each age band with tubulo-interstitial or metabolic disease, congenital nephrosis

or polycystic kidneys as the cause

0

5

10

15

20

0 - 3 4 - 7 8 - 11 12 - 15

Age group (yrs)

Pe

rce

nta

ge

of p

atie

nts

Tubular/Interstitial

Metabolic

CNS

PKD

UK Renal Registry 9th Annual Report 2006

Fig 14.14(a) Percentage of patients with renovascular diseases, malignant diseases, drug nephrotoxicity and uncertain aetiology

presenting in each age band

0

10

20

30

40

50

60

70

0 - 3 4 - 7 8 - 11 12 - 15Age group (yrs)

Per

cent

age

of p

atie

ntsRenovascular

Malignant

Drug toxicity

Uncertain

UK Renal Registry 9th Annual Report 2006

Fig 14.14(b) Percentage of patients presenting in each age band with renovascular or malignant disease, drug nephrotocicity as the cause

or uncertain aetiology

0

2

4

6

8

10

0 - 3 4 - 7 8 - 11 12 - 15

Age group (yrs)

Pe

rce

nta

ge

of p

atie

nts

Renovascular

Malignant

Drug toxicity

Uncertain

UK Renal Registry 9th Annual Report 2006

Figure 15. Distribution of modalities in paediatric patients on 1st April 2005

0

10

20

30

40

50

60

70

80

Transplant PD HD Other

Treatment

Per

cent

age

of p

atie

nts

LRD

Cadaveric

CAPD

APD

UK Renal Registry 9th Annual Report 2006

Fig 13.16 Percentage of patients with renal allografts whose graft came from a living rather than cadaveric donor

16

18

20

22

24

26

28

30

2001 2002 2003 2004 2005 2006

Year

Per

cent

age

of tr

ansp

lant

pat

ient

s w

ith a

livi

ng d

onor

UK Renal Registry 9th Annual Report 2006

Fig 13.17 Distribution of treatments according to ethnicity

0

10

20

30

40

50

60

70

80

Transplant PD HD Other

Treatment

Per

cent

age

of p

atie

nts

White

South Asian

Black

Other

UK Renal Registry 9th Annual Report 2006

Fig 13.18 ERF treatment modality changes from 2004 to 2005

81

530

73No previous ERFtreatment

No change intreatment

Treatmentchanged 2004 to2005

UK Renal Registry 9th Annual Report 2006

Figure 13.19 Distribution of treatments in those unchanged from 2004 to 2005

84%

9%7%

Transplant

PD

HD

UK Renal Registry 9th Annual Report 2006

Fig 13.20 ERF treatment changes from 2004 to 2005

1%5%

14%

4%

15%

23%

38%

Grafted from PD

Grafted from HD

Graft to PD

Graft to HD

PD to HD

HD to PD

Recovered

UK Renal Registry 9th Annual Report 2006

Fig 13.21 ERF treatment in April 2005 for those starting after April 2004