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High Performers deliver on the commercial promise of new science through outcome-driven operating models Turning science into value Biopharmaceutical Industry High Performance Business Study 1 Key Findings Confidence is back; expectations are high with companies making strategic moves 2 Return to growth is predicted but polarized between High Performers and the rest 3 Capturing the value of innovation is stretching margins and the markets' capacity to pay 4 High Performers are focusing on building dominant growth positions and reshaping operations Several operational attributes and capabilities are distinguishing High Performers: Collaborating to get the best science and break- through speed to approval and launch. Transforming their organiza- tions by leveraging partnerships, acquisitions, divestitures and asset swaps. Developing new business models in response to the consumerization of healthcare. Mastering flexible pricing and market access while demonstrating superior outcomes. Six companies are now a step change ahead of the pack, with Astellas joining for the first time and Novartis re-joining. High Performers distinguish themselves on five important metrics: Accenture’s study of the Biopharmaceutical industry is in its 10 th year and has analyzed the long-term performance of “pure-play” pharmaceutical companies (those with more than 75 percent of their revenue derived from pharmaceutical products). Our High Performance Business research methodology is a proprietary approach for analyzing relative peer company performance across six key metrics—profitability, growth, positioning for the future, longevity, consistency and revenue growth forecast, and strength of pipeline relative to intellectual property exposure. Composite scores demonstrate relative performance within the peer set and highlight the High Performers. 3 4 Rest of peer group High Performers 33.4% 27.3% Higher proportion of growth forecast to come from recent and upcoming launches as a percentage of revenue Rest of peer group High Performers 33.1% 27.7% Higher average operating margins Higher average five year revenue forecast CAGR 2015-2019 Rest of peer group 2016 High Performers 6.5% 1.3% 4.7% 1.1% Rest of peer group High Performers Higher average sales forecast for NME launches five years after launch NME launches Sales 5.3 $1.1B NME launches Sales 7.1 $0.4B Rest of peer group 1.7 High Performers 3.0 Higher five year forecast replacement revenue ratio average (ability to replace revenue lost to patent expired drugs) Copyright © 2015 Accenture All rights reserved. Accenture, its logo, and High Performance Delivered are trademarks of Accenture. Contact Us Stay Connected www.facebook.com/accenture https://twitter.com/AccentureLifSci @AccentureLifSci www.youtube.com/accenture www.linkedin.com/company/accenture Anne O’Riordan Global Life Sciences Industry Senior Managing Director Accenture Life Sciences [email protected] Andrea Brueckner Managing Director, EALA Accenture Life Sciences [email protected] Thomas D. Schwenger Senior Managing Director, North America Accenture Life Sciences [email protected] Author Philip J. Davis Head of Healthcare & Life Sciences Research Accenture Research [email protected] Visit Our Blog www.accenture.com/lifesciencesblog Accenture Life Sciences Rethink Reshape Restructure...for better patient outcomes DOWNLOAD FULL REPORT HERE 1.5 1.0 0.5 mL 1.5 1.0 0.5 mL 1.5 1.0 0.5 mL 1.5 1.0 0.5 mL $125B Recent and Upcoming NME Launches Developed Market Net Sales $190B $65B The operating margins at 11 of the 16 companies have fallen over the last two years (peer group average saw 3% fall). Drug price inflation in the US is running high at 13.2% and particularly high for specialty drugs. There is an estimated $65B gap between the predicted growth in pharma spend in developed markets and NME growth forecast. US Drug Price Specialty Drug Price 13.2% 25.2% 3% 2014-19 $ Growth Forecast Core Operating Margins 4.0 4 Year Growth Forecast (CAGR 2014- 2017) High Performance Business Score* High Performers Near High Performers Average Performers Low Performers Astellas Amgen Novo Nordisk Roche Bristol-Myers Squibb Novartis 8% 7% 6% 5% 4% 3% 2% 1% 0% -1% -2% -3% 1.0 1.5 2.0 3.0 3.5 2.5 High Performance Business Score December 2014* Versus Group Revenue Forecast CAGR (2014-17) *Based on seven year performance methodology 1 2 High Performers Rest of peer group +11% Mergers, acquisitions and divestitures are restructuring the industry. (Global Life Sciences M&A Deal Value shown) $364B 2014 177% -15% +17% 2% Q3 2014 2007 Q3 2013 Enterprise Value (EV) continues to rise. Future Value (FV) as a percentage of Enterprise Value (EV) is positive for the first time since 2007.

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Page 1: Turning science into value/_acnmedia/accent... · NME Developed Launches Market Net Sales $190B $65B The operating margins at 11 of the 16 companies have fallen over the last two

High Performers deliver on the commercial promise of new science through outcome-driven operating models

Turning science into value

Biopharmaceutical Industry High Performance Business Study

1

Key FindingsConfidence is back; expectations are high with companies making strategic moves

2 Return to growth is predicted but polarized between High Performers and the rest

3 Capturing the value of innovation is stretching margins and the markets' capacity to pay

4 High Performers are focusing on building dominant growth positions and reshaping operationsSeveral operational attributes and capabilities are distinguishing High Performers:

Collaborating to get the best science and break-through speed to approval and launch.

Transforming their organiza-tions by leveraging partnerships, acquisitions, divestitures and asset swaps. Developing new business

models in response to the consumerization of healthcare.

Mastering flexible pricing and market access while demonstrating superior outcomes.

Six companies are now a step change ahead of the pack, with Astellas joining for the first time and Novartis re-joining.

High Performers distinguish themselves on five important metrics:

Accenture’s study of the Biopharmaceutical industry is in its 10th year and has analyzed the long-term performance of “pure-play” pharmaceutical companies (those with more than 75 percent of their revenue derived from pharmaceutical products).

Our High Performance Business research methodology is a proprietary approach for analyzing relative peer company performance across six key metrics—profitability, growth, positioning for the future, longevity, consistency and revenue growth forecast,

and strength of pipeline relative to intellectual property exposure. Composite scores demonstrate relative performance within the peer set and highlight the High Performers.

3

4

Rest of peer group

High Performers

33.4%

27.3%

Higher proportion of growth forecast to come from recent and upcoming launches as a percentage of revenue

Rest of peer group

High Performers

33.1%

27.7%

Higher average operating margins

Higher average five year revenue forecast

CAGR2015-2019

Rest of peer group

2016High Performers6.5%

1.3%

4.7%

1.1%

Rest of peer group

High Performers

Higher average sales forecast for NME launches five years after launch

NME launches

Sales

5.3

$1.1BNME launches

Sales

7.1

$0.4B

Rest of peer group

1.7 HighPerformers

3.0

Higher five year forecast replacement revenue ratio average (ability to replace revenue lost to patent expired drugs)

Copyright © 2015 Accenture All rights reserved.

Accenture, its logo, and High Performance Delivered are trademarks of Accenture.

Contact Us Stay Connectedwww.facebook.com/accenture

https://twitter.com/AccentureLifSci

@AccentureLifSci

www.youtube.com/accenture

www.linkedin.com/company/accenture

Anne O’RiordanGlobal Life Sciences Industry Senior Managing Director Accenture Life Sciences [email protected]

Andrea BruecknerManaging Director, EALAAccenture Life [email protected]

Thomas D. SchwengerSenior Managing Director, North AmericaAccenture Life [email protected]

AuthorPhilip J. DavisHead of Healthcare & Life Sciences ResearchAccenture [email protected]

Visit Our Blogwww.accenture.com/lifesciencesblog

Accenture Life SciencesRethink Reshape Restructure...for better patient outcomes

DOWNLOAD FULL REPORT HERE

1.5

1.0

0.5 mL

1.5

1.0

0.5 mL

1.5

1.0

0.5 mL

1.5

1.0

0.5 mL

$125BRecent and Upcoming

NME LaunchesDeveloped

Market Net Sales

$190B$65B

The operating margins at 11 of the 16 companies have fallen over the last two years (peer group average saw 3% fall).

Drug price inflation in the US is running high at 13.2% and particularly high for specialty drugs.

There is an estimated $65B gap between the predicted growth in pharma spend in developed markets and NME growth forecast.

US Drug Price

Specialty Drug Price

13.2%

25.2%

3%

2014-19 $ Growth ForecastCore Operating Margins

4.0

4 Year Growth Forecast (CAGR 2014-2017)

High Performance Business Score*

High Performers

Near High Performers

Average Performers

Low Performers

Astellas

Amgen

Novo Nordisk

Roche

Bristol-Myers Squibb

Novartis

8%

7%

6%

5%

4%

3%

2%

1%

0%

-1%

-2%

-3%1.0 1.5 2.0 3.0 3.52.5

High Performance Business Score December 2014* Versus Group Revenue Forecast CAGR (2014-17)

*Based on seven year performance methodology

1

2

High Performers Rest of peer group

+11% Mergers, acquisitions and divestitures are restructuring the industry.(Global Life Sciences M&A Deal Value shown)

$364B2014

177%

-15%

+17%

2%

Q3 2014

2007 Q3 2013

Enterprise Value (EV) continues to rise.

Future Value (FV) as a percentage of Enterprise Value (EV) is positive for the first time since 2007.