tucker et al. 2006. am j clinical nutrition femur bone mineral density bell et al. 1977 j of...
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Tucker et al. 2006. Am J Clinical Nutrition
Fem
ur B
one
Min
eral
Den
sity
Bell et al. 1977 J of Nutrition
High Phosporus Diet Vs.
Control Diet
Population Survey (~2,500 people)Questionnaire with X-RAY for BMD
How does high Phosphorus = Lower BMD?
Phosphate (PO4
3-)
Ca2+ or Mg 2+ or Na + & PO43-
H+ or 2H+ & PO43-
50%
40%
Ca2+
PTH releasedBone breaks down releasing Ca2+Bone breaks down releasing Ca2+Kidney reabsorbs Ca2+Intestines uptake more Ca2+
In Plasma
Hydroxyapatite (Ca5(PO4)3(OH) = Storage of Calcium in Bone
Bone Resorption
Hydrochloric Acid = Dissolve Mineral
Acid Proteases (Enzymes) = Digest Bone Matrix Protiens (Collagen, etc)
Bone Structure