tsitsi g monera, phd fellow ub-uz aids training program
TRANSCRIPT
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Traditional Medicine and HIV Clinical Pharmacology:
Implementation Research
Tsitsi G Monera, PhD Fellow UB-UZ Aids Training Program
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Outline
Parirenyatwa Hospital OI clinic support group
Support group – Researcher model Herb-drug clinical study
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Parirenyatwa Hospital OI clinic support group
People with common interests and experiences
Safe space to share common concerns, verbalize emotions
Positive reinforcement, emotional support, hope
Learning environment –coping skills, self-help projects, treatment information
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Support group Researcher
model born out of the HIV-infected patients’ needs for comprehensive pharmacotherapy and the pharmacologists’ needs to explore pharmacotherapy issues in HIV-Infected patients
mutually beneficial collaboration between support group and researcher
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Prevalence of Use of Traditional Medical Systems
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Traditional Medicine
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Preliminary in vivo studies in animal models typically serve as a basis for clinical trials
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Effect of Moringa oleifera (Moringa, Drumstick, Horseradish tree) on the Pharmacokinetics of Efavirenz and Nevirapine in vivo.
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Ethical Considerations
To compare the steady-state pharmacokinetics of nevirapine and efavirenz in HIV-positive patients before and after supplementation with Moringa oleifera leaf powder
5 challenging levels of ethical and regulatory approvals (JREC, HSIRB, BRTI- exemption) Medical Control Authority (MCAZ)and national ethics committee (MRCZ)
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Acknowledgements
The program is sponsored by the UB-UZ AIDS International Training Research program funded by the Fogarty International Center.
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