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Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin, Nelly Saber, Natalie Braun, Jessica K. Fox, Majid Mojibian, Ali Asadi, Campbell Drohan, Shannon O’Dwyer, Diana S. Rosman-Balzer, Victoria A. Swiss, Alireza Rezania, Timothy J. Kieffer Stem Cell Reports Volume 4, Issue 4, Pages 605-620 (April 2015) DOI: 10.1016/j.stemcr.2015.02.011 Copyright © 2015 The Authors Terms and Conditions

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Page 1: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs 

Jennifer E. Bruin, Nelly Saber, Natalie Braun, Jessica K. Fox, Majid Mojibian, Ali Asadi, Campbell Drohan, Shannon O’Dwyer, Diana S. Rosman-Balzer, Victoria A. Swiss, Alireza Rezania, Timothy J. Kieffer 

Stem Cell Reports Volume 4, Issue 4, Pages 605-620 (April 2015)

DOI: 10.1016/j.stemcr.2015.02.011

Copyright © 2015 The Authors Terms and Conditions

Page 2: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 1

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 3: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 2

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 4: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 3

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 5: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 4

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 6: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 5

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 7: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 6

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions

Page 8: Treating Diet-Induced Diabetes and Obesity with Human Embryonic Stem Cell-Derived Pancreatic Progenitor Cells and Antidiabetic Drugs Jennifer E. Bruin,

Figure 7

Stem Cell Reports 2015 4, 605-620DOI: (10.1016/j.stemcr.2015.02.011) Copyright © 2015 The Authors Terms and Conditions