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Page 1: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer
Page 2: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Transplantation TimelineTransplantation Timeline

1905 – 1st TissueTransplant

Corneal Transplant -Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer who had been blinded by accidentally burning his eyes with caustic lime. The transplanted cornea came from an 11-year-old boy and gave Glogar sight for the

rest of his life.

Page 3: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Transplantation TimelineTransplantation Timeline

1954 – 1st OrganTransplant

A kidney transplant between

23-year-old identical twins,

Richard & Ronald Herrick, one

of who is dying from

advanced glomerulonephritis,

takes place at the Peter Bent

Brigham Hospital in Boston.

Page 4: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Transplantation TimelineTransplantation Timeline

1983 – Cyclosporine

The Food and Drug Administration approval of

cyclosporine opens the door to the modern era of organ transplantation. What had

been a marginally successful, experimental treatment - or just plain impossible – becomes

routine.

Page 5: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Small IntestineSmall Intestine

LungsLungs

KidneysKidneys

PancreasPancreas

LiverLiver

HeartHeart

Organs That Organs That Can Be TransplantedCan Be Transplanted

From a From a Deceased DonorDeceased Donor

Page 6: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

In December, 1997…In December, 1997…

53,122 individuals were on the 53,122 individuals were on the waiting list for all organs.waiting list for all organs.

As of November 1, 2013…As of November 1, 2013…120,729 individuals were on the 120,729 individuals were on the

waiting list for all organs.waiting list for all organs.

Page 7: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

WAITING LIST

120,729

53,122TOTAL

1997

2013

Page 8: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

On average, 18 people die On average, 18 people die each day in the United States each day in the United States

because they do not get a because they do not get a transplant in time.transplant in time.

More than 6,000 people will More than 6,000 people will die this year in the U.S. for die this year in the U.S. for lack of an available organ.lack of an available organ.1818

Page 9: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

The Essential IssueThe Essential IssueNeed for Organ Donation in U.S.Need for Organ Donation in U.S.

6,457 7,150 7,593 8,019 8,085 7,990 8,022 7,943 8,125 8,129

84,333 88,149 91,532 95,771 97,174100,684

107,951 110,370 112,816 116,906

0

20,000

40,000

60,000

80,000

100,000

120,000

140,000

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012

Deceased Donors Waiting List

Waiting List as of June 4, 2010

Page 10: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Population of the U.S.Population of the U.S.300,000,000 +300,000,000 +

# Actual Organ Donors/year# Actual Organ Donors/yearapproximately 8,000approximately 8,000

Deaths in US each yearDeaths in US each year2,400,000+2,400,000+

Potential Organ Donors/yearPotential Organ Donors/year 12,000 - 14,00012,000 - 14,000

Page 11: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Population of the U.S.300,000,000 +

# Actual Organ Donors/yearapproximately 8,000

Deaths in US each yearDeaths in US each year2,400,000+2,400,000+

Potential Organ Donors/yearPotential Organ Donors/year 12,000 - 14,00012,000 - 14,000

Page 12: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

LESS THANLESS THAN

1%1%

of everyone who dies of everyone who dies

can donate their organscan donate their organs

Page 13: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

In order to be considered a In order to be considered a potential organ donor when potential organ donor when

you die …you die …

You have to be deadYou have to be deadbut…but…

Your Your heart has to be pumping heart has to be pumping blood blood to your organs ? ? ? ? ? to your organs ? ? ? ? ?

Page 14: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

Brain DeathBrain Death

Page 15: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

What is Brain Death?What is Brain Death?

Brain Death Is DeathBrain Death Is Death

What does brain death mean?What does brain death mean?Brain death means there is no blood flow or oxygen Brain death means there is no blood flow or oxygen

to the brain, therefore the brain cannot function in any to the brain, therefore the brain cannot function in any capacity and never will again. It capacity and never will again. It does notdoes not mean that mean that the other organs, such as the heart, lungs, kidneys, the other organs, such as the heart, lungs, kidneys, pancreas and liver are dead, although they may only pancreas and liver are dead, although they may only function for a few days. Unless damaged by disease function for a few days. Unless damaged by disease

or injury, these organs may be used by another or injury, these organs may be used by another individual via organ transplant.individual via organ transplant.

Page 16: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

What else can be What else can be donateddonated

when someone dies ?when someone dies ?

Page 17: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

CorneasCorneas

BoneBone

SkinSkin

Femoral VeinsFemoral VeinsSaphenous VeinsSaphenous Veins

Tendons & Tendons & LigamentsLigaments

Heart ValvesHeart Valves

Tissues That Tissues That Can Be TransplantedCan Be Transplanted

Almost AnyoneAlmost Anyone

Can Be ACan Be A

Tissue DonorTissue Donor

From a From a Deceased DonorDeceased Donor

Page 18: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

IntestinesIntestines

LungsLungs

KidneysKidneysPancreasPancreas

CorneasCorneas

LiverLiver

BoneBone

SkinSkin

Femoral VeinsFemoral Veins

Saphenous VeinsSaphenous Veins

Heart & Heart ValvesHeart & Heart Valves

Organs & Tissues That Organs & Tissues That Can Be TransplantedCan Be Transplanted

Tendons & Tendons & LigamentsLigaments

From a From a Deceased DonorDeceased Donor

Page 19: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

A person dying of A person dying of brain death brain death can save the lives of can save the lives of

up to 8 people up to 8 people through organ donationthrough organ donation

and and almost anyone almost anyone can improve the lives of at can improve the lives of at

least 50 peopleleast 50 peoplethrough tissue donation.through tissue donation.

Page 20: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

What can be donatedWhat can be donated

while you are alive?while you are alive?

Living DonationLiving Donation

Page 21: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

KidneyKidney

Part of the LiverPart of the Liver

Organs That Organs That Can Be Transplanted Can Be Transplanted From a Living DonorFrom a Living Donor

Page 22: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

The liver is The liver is composed composed of 2 lobes – of 2 lobes – each having each having

its own its own blood blood

supply.supply.

Page 23: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

That can be surgically That can be surgically separatedseparated

55 55 to to

60%60%

40 40 to to

45%45%

Page 24: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

within 3 – 4 within 3 – 4 months both months both

livers will livers will regenerate to regenerate to

a full size a full size liver, but liver, but each will each will have only have only one lobeone lobe

Page 25: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

You can also donate…You can also donate…

BloodBlood

Bone marrowBone marrow

Page 26: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

What are some of the What are some of the reasons that people reasons that people

think they cannot think they cannot donate?donate?

Myths & Myths & MisconceptionsMisconceptions

Page 27: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

““Donation is against my religion.Donation is against my religion.””

Page 28: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

““ItIt’’s impossible to have a regular s impossible to have a regular funeral service following organ funeral service following organ donation.donation.””

“Donation is against my religion.”

Page 29: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

“It’s impossible to have a regular funeral service following organ donation.”

““If I am in an accident, and the hospital If I am in an accident, and the hospital knows that I want to be a donor, they knows that I want to be a donor, they will withhold treatment and not will withhold treatment and not attempt to save my life.attempt to save my life.””

“Donation is against my religion.”

Page 30: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

“It’s impossible to have a regular funeral service following organ donation.”

“If I am in an accident, and the hospital knows that I want to be a donor, they will withhold treatment and not attempt to save my life.”

““Only famous or wealthy people get Only famous or wealthy people get transplanted.transplanted.””

“Donation is against my religion.”

Page 31: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

“It’s impossible to have a regular funeral service following organ donation.”

“If I am in an accident, and the hospital knows that I want to be a donor, they will withhold treatment and not attempt to save my life.”

“Only famous or wealthy people get transplanted.”

““Donation will be costly to my family.Donation will be costly to my family.””

“Donation is against my religion.”

Page 32: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

• Enroll in the NYS Donate Life Registry.Enroll in the NYS Donate Life Registry. You You must be at least eighteen years of age.must be at least eighteen years of age.

• Talk to your family and inform them of Talk to your family and inform them of your decision.your decision.

What steps should someone take if What steps should someone take if they want to be considered to be a they want to be considered to be a

potential donor when they die?potential donor when they die?

Page 33: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

At the time of death, the At the time of death, the family is asked to consider family is asked to consider organ and tissue donation.organ and tissue donation.

or if you are under 18 and they say no, or if you are under 18 and they say no,

regardless of how old you are, regardless of how old you are, if you if you have not given legal consent have not given legal consent

and your family says no, and your family says no,

the donation process stops!the donation process stops!

Page 34: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer

If you If you want your want your final wish final wish on earth on earth

to be to be yours …yours …

You need You need to share to share that wish that wish with your with your

family.family.

Page 35: Transplantation Timeline 1905 – 1 st TissueTransplant Corneal Transplant - Austrian surgeon Dr. Eduard Zirm gives sight back to Alois Glogar, a day laborer