transitioning from improvised to safer bcpap therapy
TRANSCRIPT
Transitioning from improvised to safer bCPAP therapy
3rd WHO Global Forum on Medical Devices Gene Saxon Technical Officer PATH Thursday, May 11, 2017 Mike Eisenstein, Alec Wollen
PATH/Tom Furtwangler
What is the need for continuous positive airway pressure (CPAP) therapy?
PATH/Gabe Bienczycki
• Complications arising from respiratory distress syndrome (RDS) are responsible for the deaths of approximately 1 million babies per year. RDS is also associated with a high rate of morbidity.
• CPAP therapy is an effective treatment that has the potential to greatly improve health outcomes of premature babies with RDS.
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• CPAP is therapy that provides gentle pressure (up to 10 cmH2O) to a newborn’s lungs in order to keep them inflated.
• CPAP machines are available, but they are expensive and require a reliable source of electricity.
• However, bubble CPAP can be improvised at the point of use with tubing, a water bottle, and nasal prongs.
• Although improvising bubble CPAP is possible, many devices are not properly assembled, and may not be effective.
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What is CPAP?
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Examples of improvised bubble CPAP
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• Gentle pressure ensures that a newborn’s lungs do not collapse at the end of every breath.
• Reduces the effort required for the newborn to breathe.
How bubble CPAP works
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• Blending oxygen with air is important because too much oxygen can cause blindness, as well as damage the lungs and brain.
Pressurized O2 Blended gas
PATH air-oxygen blender
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• We have developed a bubble CPAP kit that has been tested to operate and blend with any source of pressurized oxygen.
• The kit ensures that pressure is delivered to the newborn.
• A bottle holder reduces the risk of spillage, and provides several mounting options and a scale for adjustment of pressure.
PATH/Scott Brown
Our solution: A bubble CPAP kit
• We are in the process of transferring the design to a partner manufacturer in South Africa.
• We are also planning clinical testing to determine if the device can be easily used by health care workers.
• Concurrently, we are performing market-sizing activities.
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Current work
Disclosure
This work has been conducted in collaboration with Adara Development Group; the University of Washington Department of Neonatology; Seattle Children’s Hospital; and Kiwoko Hospital, Uganda.
This presentation describes activities that are currently supported by PATH’s Innovation Fund and PATH’s Health Innovation Portfolio. The findings and conclusions contained within are those of the authors and do not necessarily reflect positions or policies of the funders.
Past support for this project was possible through the generous support of the Saving Lives at Birth partners: the United States Agency for International Development (USAID), the Government of Norway, the Bill & Melinda Gates Foundation, Grand Challenges Canada, and the UK Government. This presentation was prepared by PATH and does not necessarily reflect the views of the Saving Lives at Birth partners.
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