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Transgenic Animals

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Page 1: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 2: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 3: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 4: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 5: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

“Cloning”

Page 6: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Page 7: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Tissue specific Expression

CFTR: Cystic Fibrosis Transmembrane Conductance Regulator

Page 8: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic Animals

Tissue specific Expression

Page 9: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic animals as organ supplier

Immunological Barriers

Hyperacute rejectionAcute vascular rejectionCellular rejectionChronic rejection

Porcine endogenous retroviruses

Humanizing the pig:

Introduction of Human Genes

Knock out of pig genes -1.3 galactosyltransferase avoid immunogenic reaction

Page 10: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 11: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 12: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 13: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 14: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 15: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 16: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over
Page 17: Transgenic Animalsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · Transgenic methods The basic strategy for producing transgenic animals has not changed much over

Transgenic food

Transgenic Animals: Methodology and Applicationsstaff.unila.ac.id/gnugroho/files/2020/04/Transgenic-Animals.pdf · Transgenic Animals: Methodology and Applications •Transgenic mice:

Comparative proteomics of Bt-transgenic and non-transgenic

Transgenic mosquitoes

TRANSGENIC PLTS

Transgenic Plants

Success Story of Transgenic crops Transgenic crops

Transgenic organisms

transgenic guideline.pptx

Transgenic animals

Transgenic Crops

1 Transgenic Animals and Plants - Genetic Engineering of plant -> Transgenic plants - Genetic Engineering of animals -> Transgenic animals

Transgenic Mice - Massachusetts General · PDF fileEarly transgenic mice . ... rabbit, or pig: a) The availability of genetically homogeneous inbred strains ... transgenic transgenic

MOL.911 Molecular Biotechnology I Cloning and Expressionftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911... · MOL.602 Molecular Biotechnology I Integration – general steps Integration

MOL.911 Recombinant productsftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911... · 40 HBV genome organization. The partially double-stranded, circular RC-DNA is indicated by thick

MOL.911 Transgenic Plants - ftp.tugraz.atftp.tugraz.at/pub/Molekulare_Biotechnologie/MOL_911 Molecular... · 21 Bacillus thuringiensis Toxin Cry toxins belonging to the three domain

Transgenic drugs

Application of Transgenic Technologies on Transgenic

Transgenic technology

00 BRC 冒頭...2.09 Transgenic RBRC00297 196 Transgenic RBRC00308 171 Transgenic RBRC00309 221 Transgenic RBRC00310 HKB5 Transgenic RBRC00311 K4 C3H/HeN-Tg(H2-T18*a-3)1Yuo/Rbrc Transgenic

transgenic bacteria

Transgenic Talk

Transgenic animals

Transgenic organismspp

Transgenic Os