tranexamic acid (txa) trial study key points. inclusion criteria o trauma patients over age 18 with...
TRANSCRIPT
Tranexamic Acid (TXA) Trial Study
Key Points
Inclusion Criteria
O Trauma Patients over age 18 with sustained blunt or penetrating injury within 3 hours of patient contact time
O *Trauma base hospital contact is mandatory*
Inclusion CriteriaO Prehospital TXA should be
considered for any 18 years or older trauma patient with:O SBP < 90 at any point during patient
contact/transportO Blunt or penetrating mechanism
within 3 hours of patient contact with signs/symptoms of hemorrhagic shock
High Risk Patients O High risk patients:
O Signs and symptoms of hemorrhagic shock
O EBL of 500 mL with a heart rate greater than 120 or SBP < 90
O Uncontrollable bleedingO Amputation above wrist(s) or ankle(s)
Exclusion CriteriaO Under 18 years of ageO Any thromboembolic events within
the past 24 hours (Stroke, MI, PE)O 3 hours post injuryO Hypersensitivity or anaphylactic
reaction to TXA O Some specific injuries are excluded
as well
Exclusion CriteriaO Injury exclusion criteria:
O Penetrating cranial injuryO Isolated hanging/drowningO TBI with exposed brain matterO Cervical injury with motor deficitO Traumatic arrest with 5 minutes or
more of CPR with no ROSC
DocumentationO Description of injury/injuries to
patient(s), time of injury – key point!O Flex field added to Sansio when TXA
selected to be administeredO Trial Study tab activated in MEDS for
AMR crews
Data elementsO Date / timeO Incident numberO Patient age/gender/weight/race/ethnicity
and allergies and history / estimated blood loss
O Type of injury (blunt/penetrating)O Time and mechanism of injuryO Trauma triage criteria metO TXA dose/route/time of adminO Vital signs pre/post TXA admin – include
GCS, full BP, skin signs,
cQI O After TXA Administration, complete your
documentation and notify your cQI department
O 100% audit of all TXA PCR’sO Following patient in hospital for
continuum of careO Monitoring 24 hour mortality/morbidityO Monitoring 48 hour mortality/morbidityO Length of hospital stay and hospital
disposition