TOPICS IN (NANO) BIOTECHNOLOGY

Course Outline

2nd October, 2006

Course Outline

• Class runs every Monday, 09.00-11.00 and on every third Wednesday there will be an experimental demonstration, from October 2nd – for Nano MSc students

• Class runs every Monday, 09.00-11.00 from October 2nd – for Chem Eng PhD students

• There will a research visit to – CMN (Instituto de Microelectrónica de Barcelona) – ICMAB (Institut de Ciència de Materials de

Barcelona)» (date to be decided)

Course Outline

• The marks for the course will be based on• continuous assessment (60%)

• reports • presentations

• Final exam (20%)• Attendance (5%)

• Must pass all segments of course for overall pass mark

• The final exam consists of a multiple choice written exam and an oral presenatation

• These exams will take place at the end of the first semester

• The language of these exams will be English

Course Outline

Course Outline • Must attend at least 80% of classes

• Website with password protection for uploading and downloading relevant documents will be available from next week

• E-mail: ckosulli@etse.urv.es

• Office: 213

• Hours for visits : Tuesday and Thursday 16.00 –

18.00

Course Outline

Fundamentals of

BiotechnologyNanotechnology

Nanobiotechnology

Course Details

FUNDAMENTALS IN BIOTECHNOLOGY

• Class I• Definition of biotechnology and history

• Class II• DNA – definition, structure, arrangement in cells

• Class III• The Gene – definition, transcription, translation

• Class IV• Proteins and Protein Structure, Enzymes and Antibodies

• Class V• Recombinant DNA technology

Course Details

• Class VI• Electrophoresis, Sequencing, PCR, Molecular Beacons, Real time

PCR

• Class VII• Dining & Sleuthing with DNA

• Class VIII• Stem Cell Therapy and Gene Therapy

• Class IX• The Human Genome Project• Genomics, transcriptomics and proteomics

• Class X• Drug Discovery• Patents, intellectual property, and Tech Transfer

Course DetailsNANOTECHNOLOGY

• Class I• Nanotechnology: History, definitions and major milestones

• Class II• ‘Bottom-down’ – Nanofabrication Techniques

• Class III• ‘Top-up’- Biological self assembly

• Class IV• Nanoparticle fabrication and biofunctionalisation

• Class V• Nanotools: Microsopic techniques for characterisation and

manipulation on a nanoscale

•

Course DetailsNANOTECHNOLOGY

• Class VI• Carbon Nanotubes

• Class VII• Nanobiotechnology Applications: Diagnostics

• Class VIII• Nanobiotechnology Applications: Therapeutics

• Class IX• Nanobiotechnology Applications: DNA computing & DNA

electronics

• Class X• Nanobiotechnology Applications: Tissue Engineering / Artificial

Organs

•

Course DetailsCourse resources

• Handouts

• Downloadable documents via website

• With each class list of relevant websites provided

• Relevant literature and books will be referenced according to each topic

• Students anticipated to prepare themselves for classes of the following week and to be able to participate and contribute to the class – OPEN DISCOURSE WANTED!

Books Available

1. The Uses Of Life, A History of Biotechnology, Robert Bud

2. Industrial Enzymology, Godfrey & West

3. Biochemistry and Molecular Biology, Elliott & Elliott

4. Biomolecular Sensors, Gizelli & Lowe

5. Understanding Nanotechnology, Scientific American

6. Nanotechnology, A gentle introduction to the next big

idea, Ratner & Ratner

7. Engines of Creation, Eric Drexler

8. Our Molecular Future, Douglas Mulhall

9. Nanobiotechnology, C. Niemeyer

10. Travels to the nanoworld, M. Gross