top 10 myths and facts about hiv/aids (steve wakefield)

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    The HVTN is supported through a cooperative agreementwith the National Institute of Allergy and Infectious Diseases

    Top 10 Myths and Facts aboutHIV/AIDS

    S. Wakefield, Director External Relations

    HIV Vaccine Trials Network (HVTN)

    National Press Foundation

    August 2011

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    RECOGNIZE AND RESPOND

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    Previously in the world of HIVprevention.

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    Carl W. Dieffenbach, Ph.D.

    DirectorDivision of AIDS, NIAID

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    N = 2,235

    Cross-sectional Data

    No evidence that being circumcised

    was protective against HIV infection

    among black or Latino MSMs

    N = 3,257

    Cohort Study with Majority White

    MSMs (~19% black and Latino)

    Evidence of a 2-fold reduction in

    HIV Seroconversion withCircumcision

    Circumcision and HIV

    Seroconversion

    Among Men Who HaveSex With men in 6 US

    Cities

    SP Buchbinder et al.

    Circumcision Status

    and HIV Infection

    Among Black and

    Latino Men Who HaveSex With Men in 3 US

    Cities

    GA Millet et al.

    No Consensus on Impact of Circumcision in MSM

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    Previously in the world of HIVvaccine news

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    9

    VaxGen Lesson Misinformation

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    Media Coverage

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    __________________

    _

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    ________________________________________

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    Myths and Facts aboutHIV/AIDS

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    Casual Contact

    HIV Can BeSpread ThroughTears, Sweat,

    Mosquitoes,Swimming Pools... Toilet seat,Coughing,Restaurant,Mosquito bites,Kissing

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    www.thebody.com

    Internet Resources Abound

    Checkmarkequalsmyth

    I dont have permissionfor all images [email protected] I will remove at

    your request

    http://www.thebody.com/mailto:[email protected]://www.thebody.com/index.html?ic=3002mailto:[email protected]://www.thebody.com/
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    Disease of Other People

    HIV and AIDSonly affects gaymen and drugusers andpeople in Africa

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    Most PLWHIV are Heterosexuals

    Ask why next Thai trialwill be conducted inMSM (men who havesex with men)

    Namibia, Botswana, MalawiNo data on MSM theseHigh HIV prevalence countries

    Dr. Chris Beyrer - Hopkins

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    Death Sentence?

    I have justbeen diagnosedwith HIV andAIDS...I amgoing to die.

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    People are living well andhaving sex!

    Research continuesto unravel themystery of the

    HIV virus

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    Partnership Definitions AreChanging

    Understanding Regarding the LinkBetween Behavior and Biomedical

    Research IsChanging

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    Scientific ChallengesAlready Have One Challenge

    Finding and HIVvaccine shouldbe easy!

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    Clinical Research

    Laboratory

    Analytic/Design

    HVTN Achievements

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    -666666 -000000 -000000 -666666-00000 -666666 -666666 -666666 -000000 -666666

    Low

    Ad5 Titer

    Med

    Ad5 Titer

    Med

    Ad5 Titer

    Up-regulated Down-regulated*p

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    HVTN Pipeline

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    38 Phase I

    3 Phase II

    15 other studies HIV Infection Trials

    Tissue and Fluid Projects

    Innate Immunity

    Peru circumcision

    Population Adolescents

    At risk women

    Twins

    Evaluate vaccines& understand immune responses

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    Research has provided over 30treatments for HIV+ persons

    Once-A-DayTreatments

    New Class ofMedications CCR5 Inhibitors

    New Class of

    Medications IntegraseInhibitors

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    Berlin Patient

    HIV and AIDScan be cured.

    HIV and AIDScan be cured.

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    May 2008

    Headlines

    At Front Lines, AIDS

    War Is Falling ApartAs the Need Grows, theMoney for AIDS Runs Far

    ShortAfter Long Scientific

    Search, Still No Cure forAIDS

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    What do the Thai trial

    results mean?

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    HIV Medicine is A Specialty

    My family doctorcan treat myHIV and AIDS.

    Two Posters LegacyProject Faith Initiative& Project Vogue

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    HIV Medicine is A Specialty

    You Can't Havea Baby if You'reHIV Positive

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    Test Results May Differ ForPersons in HIV vaccine study

    An HIV test willtell me if I haveAIDS

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    How Are Most Vaccines Made

    Epi

    April 2010

    Live attenuated

    vaccines(examples: measles,mumps, andrubella)

    Whole killed

    virus vaccines(example:influenza and

    rabies)

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    Can this Vaccine give me HIV?

    The HIV vaccines

    being tested aremade from synthetic

    pieces of HIV.Therefore,

    the vaccine

    CANNOT

    cause infection.

    NO!

    34

    http://www3.niaid.nih.gov/http://www.iavi.org/
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    Our Universe

    http://www.usaid.gov/http://www.hhs.gov/http://www.niaid.nih.gov/vrc/http://www.cdc.gov/http://www.hivresearch.org/http://www.usaid.gov/http://www3.niaid.nih.gov/http://www.iavi.org/
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    When We Achieve Our Ultimate Goal

    An HIV vaccine will be given once;protection lasts a lifetime

    Durable protection is conferred to theperson at risk

    An effective vaccine is among the mostcost-effective medical interventions

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