top 10 myths and facts about hiv/aids (steve wakefield)
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The HVTN is supported through a cooperative agreementwith the National Institute of Allergy and Infectious Diseases
Top 10 Myths and Facts aboutHIV/AIDS
S. Wakefield, Director External Relations
HIV Vaccine Trials Network (HVTN)
National Press Foundation
August 2011
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RECOGNIZE AND RESPOND
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Previously in the world of HIVprevention.
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Carl W. Dieffenbach, Ph.D.
DirectorDivision of AIDS, NIAID
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N = 2,235
Cross-sectional Data
No evidence that being circumcised
was protective against HIV infection
among black or Latino MSMs
N = 3,257
Cohort Study with Majority White
MSMs (~19% black and Latino)
Evidence of a 2-fold reduction in
HIV Seroconversion withCircumcision
Circumcision and HIV
Seroconversion
Among Men Who HaveSex With men in 6 US
Cities
SP Buchbinder et al.
Circumcision Status
and HIV Infection
Among Black and
Latino Men Who HaveSex With Men in 3 US
Cities
GA Millet et al.
No Consensus on Impact of Circumcision in MSM
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Previously in the world of HIVvaccine news
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VaxGen Lesson Misinformation
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Media Coverage
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Myths and Facts aboutHIV/AIDS
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Casual Contact
HIV Can BeSpread ThroughTears, Sweat,
Mosquitoes,Swimming Pools... Toilet seat,Coughing,Restaurant,Mosquito bites,Kissing
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www.thebody.com
Internet Resources Abound
Checkmarkequalsmyth
I dont have permissionfor all images [email protected] I will remove at
your request
http://www.thebody.com/mailto:[email protected]://www.thebody.com/index.html?ic=3002mailto:[email protected]://www.thebody.com/ -
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Disease of Other People
HIV and AIDSonly affects gaymen and drugusers andpeople in Africa
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Most PLWHIV are Heterosexuals
Ask why next Thai trialwill be conducted inMSM (men who havesex with men)
Namibia, Botswana, MalawiNo data on MSM theseHigh HIV prevalence countries
Dr. Chris Beyrer - Hopkins
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Death Sentence?
I have justbeen diagnosedwith HIV andAIDS...I amgoing to die.
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People are living well andhaving sex!
Research continuesto unravel themystery of the
HIV virus
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Partnership Definitions AreChanging
Understanding Regarding the LinkBetween Behavior and Biomedical
Research IsChanging
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Scientific ChallengesAlready Have One Challenge
Finding and HIVvaccine shouldbe easy!
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Clinical Research
Laboratory
Analytic/Design
HVTN Achievements
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Low
Ad5 Titer
Med
Ad5 Titer
Med
Ad5 Titer
Up-regulated Down-regulated*p
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HVTN Pipeline
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38 Phase I
3 Phase II
15 other studies HIV Infection Trials
Tissue and Fluid Projects
Innate Immunity
Peru circumcision
Population Adolescents
At risk women
Twins
Evaluate vaccines& understand immune responses
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Research has provided over 30treatments for HIV+ persons
Once-A-DayTreatments
New Class ofMedications CCR5 Inhibitors
New Class of
Medications IntegraseInhibitors
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Berlin Patient
HIV and AIDScan be cured.
HIV and AIDScan be cured.
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May 2008
Headlines
At Front Lines, AIDS
War Is Falling ApartAs the Need Grows, theMoney for AIDS Runs Far
ShortAfter Long Scientific
Search, Still No Cure forAIDS
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What do the Thai trial
results mean?
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HIV Medicine is A Specialty
My family doctorcan treat myHIV and AIDS.
Two Posters LegacyProject Faith Initiative& Project Vogue
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HIV Medicine is A Specialty
You Can't Havea Baby if You'reHIV Positive
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Test Results May Differ ForPersons in HIV vaccine study
An HIV test willtell me if I haveAIDS
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How Are Most Vaccines Made
Epi
April 2010
Live attenuated
vaccines(examples: measles,mumps, andrubella)
Whole killed
virus vaccines(example:influenza and
rabies)
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Can this Vaccine give me HIV?
The HIV vaccines
being tested aremade from synthetic
pieces of HIV.Therefore,
the vaccine
CANNOT
cause infection.
NO!
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http://www3.niaid.nih.gov/http://www.iavi.org/ -
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Our Universe
http://www.usaid.gov/http://www.hhs.gov/http://www.niaid.nih.gov/vrc/http://www.cdc.gov/http://www.hivresearch.org/http://www.usaid.gov/http://www3.niaid.nih.gov/http://www.iavi.org/ -
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When We Achieve Our Ultimate Goal
An HIV vaccine will be given once;protection lasts a lifetime
Durable protection is conferred to theperson at risk
An effective vaccine is among the mostcost-effective medical interventions
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