to reduce antibiotic resistance - usda
TRANSCRIPT
How can we responsibly
use antibiotics in animals
without compromising
food safety and human
health, as well as animal health, welfare
and productivity?
K. Lannoo, J. Vande Ginste, G. BruggemanNuscience | Booiebos 5 | 9031 Ghent (Drongen) | Belgium | [email protected]
Thanks to a welldefi ned mode of
action and proven results in practice
it is known that the use of Medium Chain Fatty Acids (MCFA) in animal
feeds is one of the preferred solutions all over the world
to reduce the use of antibiotics.
In the search for safe and innovative
solutions Nuscience always puts the
benefi t and health of animals and
people at the center. With natural
alternatives of antibiotics, Nuscience lowers the
incidence of antibiotic resistance.
Medium Chain Fatty Acids fulfi ll where antibiotics fall short
YOUR KNOWLEDGE PARTNER IN NUTRITION AND HEALTH
Medium Chain Fatty Acids to reduce antibiotic resistance
Aromabiotic MCFA’s have proven worldwide to be a reliable partner in taking the hurdle towardsproducing animals on a cost e� ective way without using too much antibiotics.
Nuscience all rights reserved - no part of this publication may be reproduced without permission of the copyright owner.
Highly antimicrobial Improving gut health
• bactericidal at stomach level: early barrier
• very effi cient destabilisation of bacterial
cell membrane (cf. SCFA/LCFA)
• activated (no need for lipase cf. MCT)
• lower MIC values compared to SCFA
• broad spectrum: G-, G+, fungi
• Aromabiotic = synergistic mixtures: more
eff ective
• good bacteria are not inhibited by MCFA
• the benefi cial microbial ecosystem results
in higher villi lengths
• the increased absorption surface results in a
lower feed conversion ratio
Reducing pathogen virulence
• reduced virulence gene (hilA) expression
of Salmonella and its
invasion at very low
MCFA concentrations
• inhibition of microbial
lipase (virulence factor
of infectious bacteria)
Improving immunity
• less apoptosis (= programmed cell death)
of white blood cells (neutrophils)
• stronger fi rst defense against infections
• lower prevalence
of both intestinal
and non-intestinal
disorders
Ileum villi length (μm)
Control MCFA
Piglet 529 582 + 10 %
Broiler 644 752 + 17 %