Slide 1

MBBS, Dip. Card: M.Phil:TCM(China), DMCHAssistant Prof.Physiology

Thyroid GlandDr.Akbar Nawaz KhanMCQHypersecretion of Thyroxin would be caused by an increase in the release of? A) FSH or LHB) STHRH or STHC) TSH or ACTHD) TRH or TSHMCQ1) Thyroid hormones belong to which class of hormone? a) steroids b) proteins c) polypeptides d) amino acid derivatives MCQ1) Thyroid hormones belong to which class of hormone? a) steroids b) proteins c) polypeptides d) amino acid derivatives (T)MCQC-cells are present in?

a) thyroid gland

b) adrenal cortex

c) parathyroid gland

d) pituitary glandMCQC-cells are present in?

a) thyroid gland (T)

b) adrenal cortex

c) parathyroid gland

d) pituitary glandMCQThyroid gland secretes approximately ___% T4 and ___%T3? a) 20,80

b) 10,90 c) 80,20 d) 90,10MCQThyroid gland secretes approximately ___% T4 and ___%T3? a) 20,80

b) 10,90 c) 80,20 d) 90,10MCQNot an action of thyroid hormone?

a) raises BMR

b) increases cardiac output c) decreases cholesterol

d) loss of libidoMCQNot an action of thyroid hormone?

a) raises BMR

b) increases cardiac output c) decreases cholesterol

d) loss of libido (T)MCQA patient with hypothyroidism is likely to have?

a) subnormal body temperature

b) lid retraction c) exophthalmos

d) moist hands and feet MCQA patient with hypothyroidism is likely to have?

a) subnormal body temperature

b) lid retraction c) exophthalmos (T)

d) moist hands and feet MCQTrue or false regarding thyroid hormone?

a. In the circulation , thyroxin is transported bound to thyroglobulinb. I - trapping by thyroid cells does need energyc. I - is oxidized prior to iodination of thyrosined. Thyroid peroxidase inhibitors are used in the treatment of hyperthyroidisme. Low thyroxin level result in deafnessMCQTrue or false regarding thyroid hormone?

a. In the circulation , thyroxin is transported bound to thyroglobulinb. I - trapping by thyroid cells does need energyc. I - is oxidized prior to iodination of thyrosine(T)d. Thyroid peroxidase inhibitors are used in the treatment of hyperthyroidism (T)e. Low thyroxin level result in deafness (T)MCQWhich of the following act via binding directly to the receptors of the nucleus

a) Thyroxinb) ACTHc) LHd) Prolactine) Estrogen

MCQWhich of the following act via binding directly to the receptors of the nucleus

a) Thyroxin(T)b) ACTHc) LHd) Prolactine) Estrogen

MCQAll are features of adulthypothyroidismexcept?

a. Mental retardationb. Inability to tolerance coldc.Deafnessd. Bradycardiac. ConstipationMCQAll are features of adulthypothyroidismexcept?

a. Mental retardation (T)b. Inability to tolerance coldc.Deafnessd. Bradycardiac. Constipation

Mental retardation is feature ofhypothyroidismin children18MCQFactitious hyperthyrosidism , all are true except?

it is an uncommon condition due to self administration of T4

the radio-iodine uptake scan is suppressed

undetectable serum thyroglobulin

high T3:T4 ratio

the TSH is suppressed

Synthesis of thyroid hormones

Thyroxine binding globulin(TBG)Thyroxine binding PrealbuminAlbumin

BY increasing the Transition of RNABY increasing the transcription of DNA to RNABy increasing the Activity of Mitochondria

By increasing the Activity of Cellular Enzymes

iv. On Arterial Blood Pressure

On Development of Central Nervous SystemOn the Normal Function of Central Nervous System

Role of TSH

Plasma Level of TSHMode of Action of TSHRegulation of secretion of thyroid hormones

Causes for hyperthyroidism

Symptoms of hyperthyroidism

Exophthalmos

MyxedemaMCQYellowish tint of skin in myxoedema is due to? a) anaemia b) increased bilirubin level c) decreased cholesterol

d) carotenemia

Cretinism (3 months old baby) (Courtesy: Prof Mafauzy mohamad)