the use of stata in biostat teaching - fm · the use of stata in biostat teaching rino bellocco...

The use of Stata in Biostat Teaching

Rino Bellocco

University of Milano-Bicocca & Karolinska Institutet

October 21, 2008

Bellocco (Milano-Bicocca & Karolinska ) The use of Stata in Biostat Teaching October 21, 2008 1 / 29

Introduction

Outline

1 Introduction

2 Stata Progress

3 Teaching Medical Statistics, Epidemiology with Stata


Introduction

Some History

Releases of Stata

Version: 1.0-1.5, January 1985 - February 1987Version: 2.0-2.1, June 1989 - September 1990Version: 3.0-3.1, March 1992 - August 1993Version: 4.0, January 1995Version: 5.0, October 1996Version: 6.0, January 1999Version: 7.0, December 2000Version: 8.0-8.2, October 2003Version: 9.0-9.2, April 2005Version: 10.0-10.1, June 2007


Introduction


Introduction

N. J. Cox 15

Table 2: Releases of Stata

1.0 January 1985 3.1 August 19931.1 February 1985 4.0 January 19951.2 March 1985 5.0 October 19961.4 August 1986 6.0 January 19991.5 February 1987 7.0 December 20002.0 June 1988 8.0 January 20032.05 June 1989 8.1 July 20032.1 September 1990 8.2 October 20033.0 March 1992

Table 3: Stata 1.0 and Stata 1.1

append dir infile plot spoolbeep do input query summarizeby drop label regress tabulatecapture erase list rename testconfirm exit macro replace typeconvert expand merge run usecorrelate format modify savecount generate more setdescribe help outfile sort

Stata 1.0 had int, long, float, and double variables; it did not have byte or str#.


Introduction


Stata Progress

Outline

1 Introduction

2 Stata Progress



Stata Progress

Version 1 - Version 2: Some Important Steps

Survival Analysis, Kaplan-Meier estimate and Cox regression wasimplemented in its basic form in Version 2.The first Stata book was Statistics with Stata, from L. HamiltonTeaching of Statistics with Stata, or of Stata itself, has never beenthe first concern of Stata’s developers, who see Stata as primarilysoftware for research, but there has been always been strong andpositive support for people who write texts linked to Stata (A quotefrom Nick Cox)The release of Stataques: the ”student” statistical package, wherethe first version of the menu system was incorporated. LawrenceHamilton suggested a ”statistical calculator” in the program to takeadvantage of the ”immediate” commands,


Stata Progress

Version 3: much added

logistic, ologit, oprobit, clogit, mlogittobit, cnreg, rreg, qreg, weibull, eregepitabweights reconsidered: pweightsmvreg, sureg, heckman, nlreg, areg, canonnbregconstrained linear regressionml (first version)codebook


Stata Progress

Version 3: Epitab, a friend for epidemiologists

Cohort studiesir & irics & csi

Case control studiescc & ccitaboddsmhodds

Matched Case control studiescc & ccitaboddsmhodds


Stata Progress

Version 4 - Version 5

Stata marries WindowsMac version releasedStata.comglmxt commands introducedst package


Stata Progress

Version 6

web aware (use http://, updating, etc.)st rewritten


Stata Progress

Version 7

frailtycluster analysisrocStata for MAC OS XWindowed UNIXAn Introduction to Survival Analysis using Stata


Stata Progress

Version 8

graphicsextended GUI, dialog boxes available for all commandsgllamm


Stata Progress

Version 9 - Version 10

xtmixedmataimproved do editorgraphic editorexact methodspower calculation


Teaching Medical Statistics, Epidemiology with Stata

Outline

1 Introduction

2 Stata Progress




Key textbooks

Regression with graphics (Hamilton)A short introduction to Stata for Biostatistics (Hill and De Stavola):effmenuMedical Statistics (Kirkwood, Sterne)An Introduction to Stata for Health Researchers (Juul)An handbook of Statistical analysis using Stata (Rabe-Hesketh,Everitt)Statistical modeling for biomedical researchers (Dupont)



Key web: http://www.ats.ucla.edu/stat/stata/



University supporting teaching of Medical Statisticswith Stata

UCLAHarvard University, School of Public HealthJohn Hopkins, School of Public HealthKarolinska Institutet, Medical Epidemiology and BiostatisticsLondon School of Tropical Medicine and Hygiene, MedicalStatistics UnitToo many others to list



Advantage of Stata

SimpleDirectFastAffordableFun to learn and to apply



Applied Statistics

Introductory Statistics (summarize, tabulate, tabstat)Categorical Data Analysis (epitab, standardization, kappa, logistic)Analysis of Prospective Studies (epitab, poisson)Longitudinal Data Analysis (xtmixed)Survival Analysis (st,sttoc)



Statistics

MataProgrammingSimulationBootstrapping



Suggestions for Graduate teaching of Biostatistics

Discrete Survival TimeScore TestComplete longitudinal procedure


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