the use of p-values and bayes factors in genome- wide association studies professor jon wakefield
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![Page 1: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/1.jpg)
The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide
Association StudiesAssociation Studies
Professor Jon WakefieldProfessor Jon Wakefield
![Page 2: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/2.jpg)
The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide
Association StudiesAssociation Studies
Professor Jon WakefieldProfessor Jon Wakefield“Bayesian God”
![Page 3: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/3.jpg)
Jon Wakefield Jon Wakefield – career progression– career progression
Chair ISBA (read paper)
IISSBBA!A!Modeling
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Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)
• Hair
• Glasses
• Accent
![Page 5: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/5.jpg)
Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)
• Hair
• Glasses
• Accent
![Page 6: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/6.jpg)
Jon Wakefield Jon Wakefield – distinguished (easily) – distinguished (easily)
• Hair
• Glasses
• Accent
![Page 7: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/7.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Patrick Heagerty (hair, hat)
• Uncertaindirection?
• Finallyinto gear!
![Page 8: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/8.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Patrick Heagerty (hair, hat)
• Uncertaindirection?
• Finallyinto gear!
![Page 9: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/9.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Dr D Balding
• Now headsimperial group
• “Laser-like”
![Page 10: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/10.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Dr E (Balding)
• Now headsimperial group
• Likes “Lasers”
![Page 11: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/11.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Lead his field
• A ‘colorful’ character
![Page 12: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/12.jpg)
Jon Wakefield Jon Wakefield – influential figures– influential figures
• Lead his field
• A ‘colorful’ character
![Page 13: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/13.jpg)
Jon Wakefield Jon Wakefield – a family man– a family man
Looks more like…
Him in miniature!
?
![Page 14: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/14.jpg)
Jon Wakefield Jon Wakefield – a family man– a family man
Looks more like…
Him in miniature!
?
![Page 15: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/15.jpg)
Jon Wakefield Jon Wakefield – a statistical rock star!– a statistical rock star!
• Performed several unusual acts in Kensington
![Page 16: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/16.jpg)
Jon Wakefield Jon Wakefield – a statistical rock star!– a statistical rock star!
• Performed several unusual acts in Kensington!
![Page 17: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/17.jpg)
The Use of The Use of pp-values and Bayes -values and Bayes Factors in Genome-Wide Factors in Genome-Wide
Association StudiesAssociation Studies
Professor Jon WakefieldProfessor Jon Wakefield
![Page 18: The Use of p-values and Bayes Factors in Genome- Wide Association Studies Professor Jon Wakefield](https://reader035.vdocuments.us/reader035/viewer/2022062713/56649ce65503460f949b4669/html5/thumbnails/18.jpg)
professor jon professor jon WakefieldWakefield