the ultimate in core-shell performance

11
The ultimate in core- shell performance

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The ultimate in core-shell performance. 5um SpeedCore Now Available!. Fully scalable with 2.6µm SpeedCore ® Huge efficiency gains over 5µm fully porous No pressure increase versus 5µm fully porous Speed up existing 5µm methods Suitable for HPLC & UHPLC systems. Core-Shell Specification. - PowerPoint PPT Presentation

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Page 1: The ultimate in core-shell performance

The ultimate in core-shell performance

Page 2: The ultimate in core-shell performance

5um SpeedCore Now Available!

Fully scalable with 2.6µm SpeedCore®

Huge efficiency gains over 5µm fully porousNo pressure increase versus 5µm fully

porousSpeed up existing 5µm methodsSuitable for HPLC & UHPLC systems

Page 3: The ultimate in core-shell performance

Core-ShellSpecification

- 5µm

- 140m2/g

- 80Å

- 10% Carbon on C18

0.4µ

4.0µ

Page 4: The ultimate in core-shell performance

Phase Chemistries

Page 5: The ultimate in core-shell performance

Efficiency

5um Fully Porous

5um SpeedCore

0 50,000 100,000 150,000 200,000

N (p/m)

Page 6: The ultimate in core-shell performance

SpeedCore vs Fully Porous

1.7µm Full

y Poro

us

2.6µm S

peed

Core

3µm F

ully P

orous

5µm S

peed

Core

5µm F

ully P

orous

0

50

100

150

200

250

300

350

Backpressure(Bar)N/m (,000's)

Page 7: The ultimate in core-shell performance

Pradaxa – Dabigatran

0 2 4 6 8 10

5µ SpeedCore® C18 100x4.6mm50:50 25mM NH4OAc : ACN254nm1.2ml/min

Page 8: The ultimate in core-shell performance

Pradaxa – Dabigatran

0 2 4 6 8 10

50:50 25mM NH4OAc : ACN254nm1.2ml/min

5µm Speedcore® C18

5µm Fortis® C18

Page 9: The ultimate in core-shell performance

EMLA Cream

0 2 4 6 8 10

5µ SpeedCore C18 100x4.6mm20 - 80 % B in 10minsA: 25mM NH4OAc B: ACN230nm1.5ml/min

1. Lidocaine

2. Prilocaine

Page 10: The ultimate in core-shell performance

Naproxen

0 2 4 6 8 10

5µ SpeedCore C18 100x4.6mm20 - 80 % B in 10minsA: 25mM NH4OAc B: ACN230nm1.5ml/min

Page 11: The ultimate in core-shell performance

Viagra - Sildenafil

0 2 4 6 8 10

5µ SpeedCore C18 100x4.6mm20 - 80 % B in 10minsA: 0.1% Formic acidB: ACN230nm1.2ml/min