the spanish biotech sector - presentation at bioasia 2013

(07/02/2013)1

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Fondo Europeo deDesarrollo Regional (FEDER)

Una manera de hacer Europa

The Spanish Biotech sector in figures

Juan Carlos Cortés

International DirectorCentre for the Development of Industrial Technology

Ministry of Economy & Competitiveness

(07/02/2013)2

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• A young sector, 15 years old.• Internationalization is part of its DNA.• Success depends on the capacity to export.• Crucial: joint projects and technology exchange

agreements.

The Spanish Biotech sector

Spain:• Biotech industry growth in the last four years 350%• A key player in R&D, spin-offs, research and

collaboration.• Biotech: a key sector in the knowledge economy

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• Nº enterprises: 1.715 (617 EB+1.098 EIB)

• Nº personnel employed EB1+EIB2: 163.526

• Estimated turnover EB (2010): 60.122 MM€

• Internal expenditures in R&D: 568.280 M€ (11,2% increase from

2009)

• Enterprises related to human health: 67%

• Enterprises related to agro-food: 23%

• Enterprises related to industrial processing: 10%

Source: Genoma España/ASEBIOSource: Genoma España/ASEBIO

2EIB: industrial commercial or services’ enterprise, with interests, develpments and products in

biotechnology

1EB: biotechology enterprise

The Spanish Biotech sector now

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Contribution of Biotechnology tothe Spanish economy

Contribution toGDP 2010 (%)

1,2

Contribution toGDP 2010 (%)

1,2OECD predictionGDP 2030 (%)

2,7

OECD predictionGDP 2030 (%)

2,7

GDP Contribution

Employment

Macroeconomic impact of biotechnology

Contribution to GDP (%)

Predicted contribution to GDP (%)

Employment

Predicted employment

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Agriculture

Classification of Bio-companies

Food

Environment

Animal Health

Human Health

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Profile of the Biotechnology enterprise (EB) in Spain

• Between 10 and 20 employees

• Over 80% of the staff university graduates

• Over 25% of the staff devoted to R&D

• Less than 5 years of activity

• Located mostly in Madrid, Barcelona, Andalucía, País Vasco and Valencia

• Linked to prestigious public research institutions

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Spain : eight Bioregions

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The Spanish Biotech sector : scientific production (00-08)

Growth: 47% (annual rate 6%)

Source: Genoma EspañaSource: Genoma España

European contribution to world scientific production in biosciences (2000)

European contribution to world scientific production in biosciences (2008)

United Kingdom

Germany

France

Italy

Netherlands

Spain

Sweden

Belgium

Denmark

Finland

Austria

Greece

Portugal

Ireland

Luxembourg

Germany

United Kingdom

France

Italy

Spain

Netherlands

Sweden

Denmark

Belgium

Austria

Finland

Greece

Ireland

Portugal

Luxembourg

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The Biotech sector in Spain : evolution of the nº of enterprises (00-08)


Evolution of EB and EIB

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The biotech sector in Spain : total public expenditures on R&D&I biotech


Total public support for R&D&I in Biotechnology (Mio €)

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Success stories

- 2000: Pfizer invested 12m euros in its European Biometric Centre, which has support functions for the rest of Europe and USA.- 2002: Abengoa signed a 35.5million dollar R&D Agreement with the US Department of Energy.- 2002: Lilly opened its research centre for medicinal chemistry, one of the biggest in the world, investing 20 million euros.- 2003: Serono concentrates its global growth-hormone production in Spain.- 2005: GSK opens its research centre for tropical diseases in Spain.- 2009: Genzyme sets up a sales office in Madrid and has a warehouse for domestic distribution.- 2011: Celgene opens its first research centre outside the USA in Seville. The Celgene Institute of Translational Research Europe (CITRE) plans to focus on advanced therapies and regenerative medicine.

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Spanish Technology Platforms

• Biotech Markets• Nanomedicine www.nanomedspain.net/• Innovative Medicines www.medicamentos-

innovadores.org/• Plants Biotechnology www.invigen.org• Animal Health www.vetmasi.es

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CDTI DATA 2011

RTD Project and NEOTEC

Nr .of fundedcompanies

CDTI funding Total investment

92 M€48,116 M€ 64,6

INNPRONTA call

Nr. of fundedcompanies

CDTI funding Total investment

(2 Projects) 17 M€ 27,67 M€ 32,56

Indo-Spanishcall CDTI-DBT

Nr. of proposals Selectedprojects

First call 2012 7 3

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Potential areas for cooperationSPANISH TECHNOLOGICAL STRENGTHS

Health and Nano biotechnology

Some Developments in 2011 • Oncology,: Advancell, GP Pharm, Ingenasa, Pharmamar, IUCT, Lipopharma, Entrechem,

Orizon Genomics

• Cardiology/ Neurological: Neuron Pharma, Sanifit,

• Oftalmology: Sylentis, Proretina Therapeutics, Biotechnology Institute, Bioftalmic

• Vaccines: Archivel Farma, Ferrer, Rovi, Leti

• Biotech diagnosis, biomarkers, nanomedicine: Orizon Genomics, Sistemas Genomicos, AB

BIOTICs, Genomica, Biobide, Pangaea Biotech, Genetadi Botech, Aromics, Nanotherapy,

Nanoinmunotech…

• Animal Health: Bionaturis, Ingenasa

• Bioinformatic: Integromics, Noray Bio, Biomol Informatics

• Regenerative medicine, Cell and Gene therapy: Tigenics (former Cellerix)

• Biofuels: Abengoa, Repsol

4th Nano biotechnology Scientific production in the world • Barcelona the 2nd Nano biotech city (1st Boston)

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www.asebio.com

• ASEBIO is the Spanish Asociation of Biocompanies

• ASEBIO belongs to and is supported by EUROPABIO, and is a part of CEOE and SEBBM

Institutions supporting the sector in Spain:

Promoting value creation through knowledge

the spanish biotech sector - presentation at bioasia 2013

Business

hacer europa

eib unin europea fondo

research centre

contribution of biotechnology

key sector

young sector

n of enterprises

biotech industry growth