The Potency of Faloak's (Sterculia quadrifida R.Br 1844) Active Compunds As Natural Remedy

Kupang Forest Research Institute

Bogor, 11 September, 2013

By: 1. Siswadi 2. Dani S. Hadi 3. Grace S. Saragih 4. Heny Rianawati

Potential “S.Quadrifida R.Br”

Local wisdom

In Timor, the bark of faloak believed to cure various diseases such as. liver, rheumatic, treat to blood vomit, cancer, diabetes, and digestive disorders

growing on rock

altitude of 0-900 m asl.

Faloak tree can reach height up

to 15 m or more.

The purpose of this study was to determine the active compounds of faloak bark and benefits of them for humans health.

Faloak bark samples were taken in the city of Kupang on growing altitude 200 m asl.

The powder of faloak bark

+ Acetone / n. Hexane / Diethyl Ether / Ethyl acetate is stirred for 10 minutes let stand 24 hours, strain. Repeat 3 times

Residue Filtrate

Evaporated with a rotary vacuum evaporator water bath temperature of 50 ° C

Extract of faloak bark

Flow chart of faloak bark extraction

Sample Anaysis : The Integrated Research and Testing Laboratory, “LPPT” Gadjah Mada University. and analyzed in July to August 2012. Extracts obtained from maceration method using four solvents; acetone, n-hexane, diethyl ether, and ethyl acetate.

the aim to identify the main compounds in the faloak bark include alkoloid, flavonoids, saponins, phenolic and terpenoids.

Weight of faloak bark

(wet)

Weight of faloak bark

(dry)

Drying shrinkage

20 gram 9,870 gram 49,35%

20 gram 9,220 gram 46,10%

20 gram 9,430 gram 47,15%

Average 47,53%

Making Extract

Fraction

(solvent)

Weigh of the

powder bark

(gram)

Weight of the

resulting extract

(mg)

Percentage of

extract (%)

Acetone 25 1.730 6.92

n Hexane 25 100 0.4

Diethyl eter 25 273 1.09

Ethyl

acetate

25 110 0.44

Water 25 1.170 4.68

The extraction results illustrate that the fraction of acetone is the best type of fraction for extracting of faloak bark are 1.730 mg or 6.92%.

The phytochemical test results bark faloak

Name of the

test

compound

Qualitative chemical analysis

Aceton

extract Eter extract

Etil Asetat

extract

Heksan

extract

Alkaloid - + + +

Flavonoid + + + +

Saponin - - - -

Phenolic + + + -

Terpenoid + + + +

Name of

compound Function

Alkaloid increase blood pressure, reduce pain, antimicrobial, sedative,

medication for heart disease and else (Robinson, 1995).

Flavonoid antibiotic against cancer and kidney, inhibits bleeding,

antioxidants, controlling free radicals, reduce blood clotting and

for the recovery of dead/damaged cells in the liver. (Birt et al.,

2001)

Saponin ability to bind cholesterol. Arcuri P.B. (2004)

Fenolik (Meskin. et.al. Within Nurmillah 2009) anti-aging antioxidant and

antitumor effects.

Terpenoid cure skin disorders, antifugus, antibacterial and antiviral

(Robinson, 1995).

Shrinkage caused by water loss from the faloak bark at the drying process is equal to 52.47%.

Aceton fractions produce the most many extracts the faloak bark.

Flovonoid, and Terpenoids can be extracted using four types of solvents (Aceton, Ether, Ethyl acetate, Hexane), while saponin was not found in the faloak bark.