the mrf genome library: epidemiology of meningococcal disease-causing lineages in england and wales...
DESCRIPTION
Dorothea Hill's presentation on her poster at Meningitis Research Foundtion's 2013 conference, Meningitis & Septicaemia in Children & AdultsTRANSCRIPT
The MRFMeningococcus Genome Librarywww.meningitis.org/research/genome
Dorothea HillUniversity of Oxford
MRF conference 2013Wednesday 6th November
‘Publicly accessible data requires a stable home and someone to pay the mortgage.’ Dr. Francine Berman, Research Data Alliance
MRU: Isolates
Illumina genome sequencing
BIGS databasehttp://pubmlst.org
Funding
Whole-genome population structure with ‘Genome Comparator’: two CC269 (lineage 2) sub-lineages.
100 locilineage 5 (CC32)
lineage 2.2Incl. ST-275, ST-1161 lineage 2.1
Incl. ST-269, ST-467, ST-283
261 loci
451 loci
Community improvement of the MRF Genome Library.
Jolley, K. and M. Maiden, Automated extraction of typing information for bacterial pathogens from whole genome sequence data: Neisseria meningitidis as an exemplar. Euro Surveill, 2013.
Meningococcal Reference Unit:Ray Borrow, Jay Lucidarme, Steve Gray
Pathogen genomics:Julian Parkhill, David Harris
Maiden Group: Martin Maiden, Keith Jolley, James Bray