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Name: _________________________ Extra Credit Assignment 08 Page 1 of 10 The Inner Life of the Genome Scientific American February 2011

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Name: _________________________ Extra Credit Assignment 08

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The Inner Life of the Genome Scientific American – February 2011

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The Inner Life of the Genome Scientific American – February 2011

1. How was it figured out that chromosomes only occupied certain areas of a nucleus?

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2. What have observations about the GFAP and IGH genes revealed about gene location?

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3. What are transcription factories?

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4. How does differentiation affect gene regulation?

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5. Describe the role of chromosomal positioning in some cancers. _____________________________________________________________________________

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6. How is (the above) useful in diagnosis of these types of cancer?

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7. Describe the self-organization model of a cell nucleus.

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