The Inflammatory Breast The Inflammatory Breast Cancer Cancer RegistryCancer Cancer Registry

Paul H. Levine, M.D.Paul H. Levine, M.D.

The George Washington University The George Washington University School of School of Public Health and Public Health and Health ServicesHealth Services

paulhlevine@earthlink.netpaulhlevine@earthlink.net

202-994-4582202-994-4582

Purpose of the IBCRPurpose of the IBCR

To improve the AJCC case definition of To improve the AJCC case definition of IBCIBC

This involves collecting standardized This involves collecting standardized clinical and epidemiologic information on clinical and epidemiologic information on patients with IBC diagnosed in the patients with IBC diagnosed in the United States and CanadaUnited States and Canada

And collecting biospecimens from these And collecting biospecimens from these patients to determine whether the patients to determine whether the molecular patterns correlate with the molecular patterns correlate with the clinical patterns of disease.clinical patterns of disease.

Current StatusCurrent Status

163 patients enrolled163 patients enrolled Lab studies ongoing with GW (Dr. Lab studies ongoing with GW (Dr.

Berg), NCI (Dr. Swain et al.) and Berg), NCI (Dr. Swain et al.) and others. Tissues still availableothers. Tissues still available

The Role of Race and The Role of Race and Poverty in Determining Poverty in Determining Cancer Patterns in the Cancer Patterns in the District of ColumbiaDistrict of Columbia

Paul H. Levine, M.D.Paul H. Levine, M.D.

ObjectivesObjectives To examine cancer incidence rates based on To examine cancer incidence rates based on

cases diagnosed in DC during 1997-2001. cases diagnosed in DC during 1997-2001. To determine if cancer incidence rates were To determine if cancer incidence rates were

associated with an indicator of associated with an indicator of socioeconomic status as well as race.socioeconomic status as well as race.

To relate available data on socioeconomic To relate available data on socioeconomic status, screening behavior and cancer status, screening behavior and cancer mortality. mortality.

To explore the possibility of developing To explore the possibility of developing population-based case- control studies in DCpopulation-based case- control studies in DC

Conclusions Conclusions

Among black males and females, a significant Among black males and females, a significant inverse trend in lung cancer incidence rates inverse trend in lung cancer incidence rates with SES correlated with current smoking rates with SES correlated with current smoking rates in these populations. in these populations.

Overall, cancer incidence and mortality are Overall, cancer incidence and mortality are higher in D.C. than the U.S.higher in D.C. than the U.S.

Breast cancer incidence correlated with Breast cancer incidence correlated with socioeconomic status in Blacks but not Whitessocioeconomic status in Blacks but not Whites

Breast cancer incidence and mortality rates in Breast cancer incidence and mortality rates in both Whites and Blacks are higher in DC vs. both Whites and Blacks are higher in DC vs. SEER.SEER.

Conclusions IIConclusions II

Low SES black women were more Low SES black women were more likely to have had a mammogram in likely to have had a mammogram in the past two years than low SES white the past two years than low SES white women, but the reverse was true for women, but the reverse was true for high SES black women vs. white high SES black women vs. white women.women.