the infectious diseases institute kampala, uganda infopoverty world conference united nations...
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The Infectious Diseases InstituteKampala, Uganda
The Infectious Diseases InstituteKampala, Uganda
InfoPoverty World Conference
United Nations
InfoPoverty World Conference
United Nations
Robert L. MallettSenior Vice President
Corporate AffairsPfizer Inc
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What We DoWhat We Do
Source: PhRMA, based on data from Center for the Study of Drug Development, Tufts University, 1995
5,000–10,000Screened
5,000–10,000Screened
250Enter Preclinical
Testing
250Enter Preclinical
Testing
5Enter
Clinical Testing
5Enter
Clinical Testing
1Approved by
the FDA
1616
1414
1212
1010
88
66
44
22
00
Phase II100–300 Patient Volunteers Used to Look for Efficacy and Side Effects
Phase III1,000–5,000 Patient Volunteers Used to
Monitor Adverse Reactions to Long-term Use FDA Review Approval
Additional Post-marketing Testing
Phase I 20–80 Healthy
Volunteers Used to Determine Safety and
Dosage
Preclinical TestingLaboratory and Animal Testing
Discovery(2–10 Years)
Compound Success Rates by Stage
Compound Success Rates by StageYears
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• Effective Social Investment• We Focus on Where We Add the Greatest Value
– Long-Term Commitment to Health Problems– Focus on Achievable,
Measurable Health Outcomes– Leverage the Full Resources
of the Company– Fostering Innovative Approaches
to Public Health Challenges• We Have More to Offer Than Money
– Medicines, Organizational Influence, Leadership, and Our People
• We Cannot Do It Alone– We Work in Partnership
• Effective Social Investment• We Focus on Where We Add the Greatest Value
– Long-Term Commitment to Health Problems– Focus on Achievable,
Measurable Health Outcomes– Leverage the Full Resources
of the Company– Fostering Innovative Approaches
to Public Health Challenges• We Have More to Offer Than Money
– Medicines, Organizational Influence, Leadership, and Our People
• We Cannot Do It Alone– We Work in Partnership
What We BelieveWhat We Believe
Guiding PrinciplesGuiding Principles
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How We HelpHow We Help
Access to MedicinesAccess to Medicines
• Infrastructure Development
• Health Provider Training
• Company Expertise
• Patient Education
• Pfizer People
• Infrastructure Development
• Health Provider Training
• Company Expertise
• Patient Education
• Pfizer People
Global Health: Systemic Improvements in Building Capacity
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Health Care in Uganda: Challenges and Opportunities Health Care in Uganda: Challenges and Opportunities
• Absence of Primary Health Care Infrastructure
• Lack of Trained Health Care Professionals
• Transient, Mobile Patient Populations
• Lack of Equipment and Medical Facilities
• Vertical Programs
• Absence of Primary Health Care Infrastructure
• Lack of Trained Health Care Professionals
• Transient, Mobile Patient Populations
• Lack of Equipment and Medical Facilities
• Vertical Programs
• Responsive, Engaging Government
• Existing Medical School with Significant HIV/AIDS Expertise
• Stable Environment
• Resources and International Donors
• Responsive, Engaging Government
• Existing Medical School with Significant HIV/AIDS Expertise
• Stable Environment
• Resources and International Donors
OpportunitiesOpportunitiesChallengesChallenges
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Infectious Diseases Institute, Kampala, UgandaInfectious Diseases Institute, Kampala, Uganda
Goal: To Build and Sustain Regional Clinic, Laboratory and Medical Training Center for the Diagnosis, Treatment and Prevention of HIV/AIDS
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Model PartnershipModel Partnership
• Makerere University in Kampala– One of the Leading Medical Schools on the Continent
• San Francisco AIDS Foundation/Pangaea– Program Administration and Project Manager for Construction
• Infectious Diseases Society of America (IDSA)– Developed Intensive Month-Long HIV/AIDS Training
Curriculum and Provides Trainers
• The AIDS Support Organization (TASO) – Largest Indigenous Organization in Africa Providing Patient
Counseling and Support
• Pfizer– Financial Support and Technical Assistance (e.g. Pfizer Engineers and IT Support; Medicines; Pfizer Global Health Fellows)
• Makerere University in Kampala– One of the Leading Medical Schools on the Continent
• San Francisco AIDS Foundation/Pangaea– Program Administration and Project Manager for Construction
• Infectious Diseases Society of America (IDSA)– Developed Intensive Month-Long HIV/AIDS Training
Curriculum and Provides Trainers
• The AIDS Support Organization (TASO) – Largest Indigenous Organization in Africa Providing Patient
Counseling and Support
• Pfizer– Financial Support and Technical Assistance (e.g. Pfizer Engineers and IT Support; Medicines; Pfizer Global Health Fellows)
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Matching Needs to ResourcesMatching Needs to Resources
IDI Technology Needs
• Infrastructure/Wiring
• Integration of Clinical Laboratory System
• Identification and Implementation of an Electronic Record Keeping System
• Installation of a Research Database to Administer Data Collection for Clinical Trials
• Creation of a Clinical Training Program for New Physicians
IDI Technology Needs
• Infrastructure/Wiring
• Integration of Clinical Laboratory System
• Identification and Implementation of an Electronic Record Keeping System
• Installation of a Research Database to Administer Data Collection for Clinical Trials
• Creation of a Clinical Training Program for New Physicians
Donors
($1.8M in IT support )
• Pfizer
• Microsoft
• Cisco
• SAS
• Oracle
• Hewlett Packard
• Elsevier Science
• Skyscape
• PALM Inc
Donors
($1.8M in IT support )
• Pfizer
• Microsoft
• Cisco
• SAS
• Oracle
• Hewlett Packard
• Elsevier Science
• Skyscape
• PALM Inc
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Impact of Infectious Diseases InstituteImpact of Infectious Diseases Institute
Training
• 200 Physicians Trained Each Year
Treatment
• 3,000+ Patients Receive Regular Care
Operational Research
• New Studies on Adherence
Prevention and Outreach
• Counseling for Patients
• AIDS Center Provides Information for Physicians
Training
• 200 Physicians Trained Each Year
Treatment
• 3,000+ Patients Receive Regular Care
Operational Research
• New Studies on Adherence
Prevention and Outreach
• Counseling for Patients
• AIDS Center Provides Information for Physicians
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Critical But Unforeseen Benefits Critical But Unforeseen Benefits
• Workplace Safety Program– Transferring World Class Health & Safety Standards
• Makerere School of Architecture– Students Benefiting From Project Engineering and
Architecture
• Local Procurement of Resources– Support Kampala Economy
• Creating Entrepreneurial Opportunities– Local Contracting Company Won Bid to Construct
New British High Commission
• Sharing Best Practices– Pfizer Promoting Lessons Learned
• Workplace Safety Program– Transferring World Class Health & Safety Standards
• Makerere School of Architecture– Students Benefiting From Project Engineering and
Architecture
• Local Procurement of Resources– Support Kampala Economy
• Creating Entrepreneurial Opportunities– Local Contracting Company Won Bid to Construct
New British High Commission
• Sharing Best Practices– Pfizer Promoting Lessons Learned