the crashing asthmatic

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EmergencyMedicineIreland.com The Crashing Asthmatic

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Post on 23-Aug-2014

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Brief talk on evidence for treatment strategies in the crashing asthmatic. More info here http://emergencymedicineireland.com/2013/05/the-crashing-asthmatic/

TRANSCRIPT

Page 1: The Crashing Asthmatic

EmergencyMedicineIreland.com

The Crashing Asthmatic

Page 2: The Crashing Asthmatic

EmergencyMedicineIreland.com

The Basics

Beta2 agonists +++

Page 3: The Crashing Asthmatic

EmergencyMedicineIreland.com

Non-response to salbutamol

Genetics vs Tachyphylaxis

Page 4: The Crashing Asthmatic

EmergencyMedicineIreland.com

Why IV?

Page 5: The Crashing Asthmatic

EmergencyMedicineIreland.com

Magnesium

2009•7 Studies (5 Adult; 2 Kids)•665 pts

Page 6: The Crashing Asthmatic

EmergencyMedicineIreland.comcredit: http://www.freeimageslive.co.uk/

Page 7: The Crashing Asthmatic

EmergencyMedicineIreland.com

Aminophylline2012•15 Studies•817 pts

Page 8: The Crashing Asthmatic

EmergencyMedicineIreland.com

2012•3 Studies•100 pts

IV Salbutamol

Page 9: The Crashing Asthmatic

EmergencyMedicineIreland.com

IV Salbutamol

PMID: 16548805

Page 10: The Crashing Asthmatic

EmergencyMedicineIreland.com

Now entering an evidence free zone...

Page 11: The Crashing Asthmatic

EmergencyMedicineIreland.com

Adrenaline

Neb/IM/SC/IV

Page 12: The Crashing Asthmatic

EmergencyMedicineIreland.com

2012•5 Studies •206 pts

Non-Invasive Ventilation

↑FRC↓WOB

Page 13: The Crashing Asthmatic

EmergencyMedicineIreland.com

When to intubate?

Wait till you would normally intubate someone...

Wait some more...

But not too long...

Page 14: The Crashing Asthmatic

EmergencyMedicineIreland.com

Intubation

Ketamine•bronchodilator

•pre and for induction•? problems with secretions

Lignocaine•IV and inhaled

•reduced airway responsiveness

Page 15: The Crashing Asthmatic

EmergencyMedicineIreland.com

Difficult Ventilation

Credit: http://emcrit.org/podcasts/severe-asthmatic/

Page 16: The Crashing Asthmatic

EmergencyMedicineIreland.com

Ventilation

Low PEEPAdequate flow ratesReally, really big I:E ratios

Deterioration?•disconnect the vent•squeeze the chest•pleural decompression•fluid loading

Page 17: The Crashing Asthmatic

EmergencyMedicineIreland.com

Role for ECMO?

Page 18: The Crashing Asthmatic

EmergencyMedicineIreland.com

thanks for watching