the comprehensive treatment for oily and blemished...

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The comprehensive treatment for oily and blemished skin

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Comodex is a potent combination of botanical extracts and highly effective active ingredients in advanced technological delivery systems.

The line displays enhanced penetration capabilities, which ensure a more effective activity and delivers much faster results.

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• Caused by oily & problem skin

• For post inflammatory hyper pigmentation

• For woman and man of all ages

• All skin tones

Comodex – Who is the treatment for?

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• Blending the best of nature and science, Comodex

purifies, balances and renews the skin, restoring it to

its healthiest condition

• Comodex all around treatment addresses the primary

causes of oily skin and blemishes, speeding up healing

processes and preventing further damage.

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• Hormonal imbalance

• Genetic predisposition

• Bacterial infections together with poor hygiene

• Stress

• Imbalanced nutrition…

Comodex treats symptoms and manifestations of various problems caused by oily skin.

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Comodex is a unique treatment leading to proven, long lasting results.

• Decrease in new comedones

formation

• Decrease in new scars appearance

• Skin renewal & Cell regeneration

• Prevention of hyper pigmentation

• Increase in elasticity

• Removal of excessive sebum

• Decrease of sebum secretion

• Softening of comedones

• Prevention of bacterial

proliferation

• Decrease of redness

Long term benefits: Short term benefits:

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The Science Behind

Each featuring effective active ingredients in advanced technological delivery systems with powerful penetration capabilities.

Delivery systems incorporate, stabilize, protect, solubilize and correctly target through the skin barrier

Comodex treatment relies on four well defined processes.

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Cleansing and Purifying

Moderating sebum

secretion

Exfoliation and Renewal

Prevention of post

inflammatory hyper

pigmentation (PIH)

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Exfoliation and RenewalEncapsulated Salicylic AcidA time release delivery system for salicylic acid (SA). SA works as a keratolytic, comedolytic, and bacteriostatic agent. Benefits:• It is skin-friendly, preventing dryness and irritation. • Sustained release of SA over time allows for effective, long-

lasting, and nonirritating delivery. • Making it suitable for sensitive skin.• Causing the epidermis cells to shed more readily, opening

clogged pores, and neutralizing bacteria within

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Renewal - Perfection PeptidePerfection Peptide P3 is based on a biomimetic tripeptide designed and vectorized to target the outermost stratum corneum, where desquamation takes place. Benefits:• Enhanced skin renewal • Increased skin hydration and smoothness • Reduction in wrinkle depth in the crow’s feet area& irregularities age signs• Reactivating and balancing the desquamation process • Improvement of the skin quality

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Speeds up epidermal renewal

• As corneocytes cells loose cell to cell contact, desquamation with Perfection peptide speeds up epidermal renewal. As a result, the skin becomes smooth, and rejuvenated.

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Smoothing effect after 4 weeks

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The microcapsules break when they are applied to the skin so that the retinol is at its most active when deliveredBenefits: • Effective at reducing visible wrinkles & fine lines• Reducing age spots. • Boosts cell regeneration together with collagen and HA

production• Leading to a more elastic and even toned skin.

Encapsulated retinol - Exfoliation and Renewal

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Prevention of post inflammatory hyper pigmentation (PIH)

Stable vitamin C• A new stable form of vitamin C stabilized with glucose. The glucose

bond protects vitamin C from degradation and loss of efficacy. Melanocyte cells treated with AGS demonstrated a reduction in the melanin synthesis, hence the ability to obtain less pigmentation and a lighter even-tone skin appearance.

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melanocytes cell before & after 48h AGS treatment

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Whitening PeptideTGF-ß biomimetic encapsulated peptide to decrease skin pigmentation inhibits melanin production in 2 ways: 1. It inhibits MITF activity, thus decreasing the production of melanocytes and melanin. 2. It decreases the expression of TGF-B factor (receptor connection.

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This unique Whitening peptide allows optimal lightening effect for a brighter, even-toned skin.

Melanin synthesis

in melanocytes

Thyrosinase activity in

melanocytes

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Marine C Thiopeptide• A marine origin non-irritating active helps relieve blemishes and reduce

redness and inflammation without harsh and drying effects.

• It speeds up recovery and prevents adverse reactions.

• In vitro efficacy tests were performed to verify anti-inflammatory and anti-bacterial properties.

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Cleansing and PurifyingMarine C Thiopeptide

• A marine origin non-irritating active helps relieve blemishes and reduce redness and inflammation without harsh and drying effects.

• speeds up recovery and prevents adverse reactions.

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Anti-blemish efficacy test Duration of 4 weeks application once a day.

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Moderating sebum & mattifyingNio-Sebactive - carried by niosoma, a novel drug delivery system.• A powerful combination of nobiletin, oleanolic acid and

saw palmetto extract. Benefit:• designed to reduce sebum production and shininess• It reduces a major lipid component in the sebum. • It inhibits 5a-reductase.

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In Vitro test show inhibitory effect of Nio-Sebactive on 5α-reductas

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In Vitro test show inhibitory effectof Nio-Sebactive on 5α-reductase

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A significant reduction of sebocytes cell proliferation rate of apx. 40% decrease is shown with only 1% active

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Pore Reductyl Pore refiner with multiple properties• Cutaneous astringency• Pore tightening • Pore Reductyl Moisturizing effect• Pore Reductyl’s

Clinical studies have proven this effectiveness with a reduction of pore size and number

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Xpertmoist• Preservative-free molecular film bases on alga extract,

containing specific active ingredients, rich with natural NMF & regenerating factors.

• This occlusive improved delivery system has a great contact surface with the skin, minimizing the TEWL and helping the active ingredients to penetrate more efficiently, leaving the skin more supple and replenished.

Hydrating & Soothing

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• A moisturizing study on female volunteers shows a significant and immediate moisture increase of 21.8% just after 24h from application and a long lasting effect of 32.5% after 21 days from application.

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Tasman pepper extract

• Natural Australian active ingredient extracted from the Tasmanian pepper berry.

• Treats edema, erythema and skin discomfort. Relieves instantly itching discomfort and provides a fast relief from unpleasant sensations.

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• Moreover, a clinical study on volunteers demonstrates that this active immediate relieves itching discomfort. The itching sensations were reduced by 79% after only 5 min.

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Salon Treatment Protocol

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Step 1Clean & Clear CleanserAnti bacterial soap, removes dirt and makeup residue,leaves the skin clean and comfortable.

• Marine C Thiopeptide - anti inflammatory and anti bacterial. Reduces incidence of comedones and speeds up the healing process.

• Citric acid – lightening agent, boosts collagen formation, improves elasticity.

• Lycopene – potent anti microbial and anti inflammatory, protects against toxicity, antioxidant.

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Gentle, creamy scrub exfoliates, removes impurities and oil residue from the depth of pores. The skin appears smooth, with a uniform texture.

• Apricot beads – provide excellent exfoliation.

• Liquorice extract &

• Stable vitamin C– lightening agents with anti oxidant and soothing properties.

Step 2Scrub & Smooth Exfoliator

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Step 3A.Treat & Regenerate PeelRemoves dead cell, boosts cell regeneration.Strong anti bacterial activity. Inhibits melanin production

Glycolic & lactic AHA’s – stimulate cell regeneration.

Kojic & bearberry extracts – inhibit the formation of melanin.

Encapslated salicylic acid - formation removes dead cells, rids the skin of excessive oil and bacteria

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Step 3 B. Peel & Renew forte peelForte treatment to increase cell turnover and collagen production. Provides smoother texture and brighter skin appearance, Removes dead cell, boosts cell regeneration, Inhibits melanin production & haze a Strong anti bacterial activity.

Encapsulated retinol – retinyl ester ensures maximum penetration and cell division and regeneration together with collagen and HA production.

Glycolic acid– stimulates cell regeneration.Encapslated salicylic acid - removes dead cells, rids the skin of excessive oil and bacteria.

Lime pearl - a new mechanism for gentle exfoliation for a brighter and even toned complexion.

Perfection peptide -enhanced skin renewal & hydration, balances the desquamation process.

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Step 3 C. Peel & Repair forte PLUSForte Plus treatment formulated to boost skin renewal . Tone, smooth & Improves skin texture, Blurs blemishes, repair and prevent scars formation.

Glycolic acid –stimulates cell regeneration.

Stable vitamin C -antioxidant, reduces inflammation and irritation, boosts collagen production.

Vitamin B – speeds up recovery from acne.


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Step 4.Stimulate & Detox SolutionStimulating solution to boost blood circulation and improve cell metabolism. Detoxifies and increases oxygen in cells. Antiseptic properties enable effective sebum extraction.

Cinnamon extract –anti bacterial and purifying properties.

Paprika extract – stimulates and warms the skin, boosting circulation and cell metabolism.

Green tea extract – anti microbial, anti inflammatory and radicals scavenger.

Stable vitamin C - lightening agent, anti oxidant, promotes collagen synthesis. .

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Step 5Bright & Balance SolutionBlurs visibility of post acne spots, promoting an even toned complexion & Prevents post inflammatory hyper pigmentation. Kojic & bearberry extracts – inhibit the formation of melanin.

Encapsulated retinol – retinyl ester ensures maximum penetration, cell division and regeneration together with collagen and HA production.

Stable vitamin C - lightening agent, anti oxidant, promotes collagen synthesis.

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Step 6 Astringe & Regulate MaskReduces sebum production and helps absorb excessive oiliness. Anti bacterial, calms irritated skin and helps shrink open pores.

Kaolin, calamine & zinc oxide – mineral complex to absorb excessive sebum and conceal blemishes.

Sulfur - controls sebum production while absorbing excessive oil.

Pore-reductyl - with anti-inflammatory, astringing and tightening effect.

Lycopene – potent anti microbial and anti inflammatory, protects against toxicity, antioxidant.

GP4G - a unique plankton extract that energizes and protects skin from environmental aggressors.

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Step 7Mattify & Protect Cream SPF 15Lightweight cream enriched with moisturizers provides prolonged protection against sun and environmental damage. Boosts natural regeneration and eliminates excessive shininess

Kollaren – biomimetic peptide stimulates the production of the ECM components (collagen I & III, fibronectin, elastin & laminin).Help increase skin firmness,improves tissue renewal & speeds up healing.

Pentavitin – complex of nutrients and moisturizers

UVA+UVF sun filters – wide spectrum sun filters

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OPTIONALCover & Shield Cream SPF20Lightweight cover cream conceals blemishes and redness, leaving the skin uniform and even toned. Protects against environmental damage, fights free radicals and speeds up healing processes

Zinc oxide – calms irritated, red skin and provides physical protection against damaging sun rays.

Bisabolol - anti inflammatory and soothing.

Kalpariane - free radicals scavenger, promotes synthesis of HA, collagen and elastin.

Camouflage – conceals imperfections

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Comodex Home Care Protocol

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Clean & Clear CleanserAnti bacterial soap, removes dirty and makeup residue, leaves the skin calm.

Marine C Thiopeptide - anti inflammatory and anti bacterial. Reduces incidence of comedones and speeds up the healing process.

Citric acid – lightening agent, boosts collagen formation, improves elasticity.


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Purify & Balance TonerInvigorating toner with anti septic properties. Purifies and balances the skin. Removes pore clogging pollutants and prevents future breakouts and blemishes. Melafresh T96 - broad-spectrum antimicrobial and anti-inflammatory activity. Reduces UV-induced erythema, improves and soothes acne-prone skin. Eukalyptus extract- antibacterial, antifungal, and antiviral properties. Tasman pepper extract – immediate soothing action, comforts and calms the skin. Has antioxidant and anti inflammatory properties.

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Control & Regulate Day TreatmentTreatment gel reduces sebum secretion and excretion, helps absorb excessive oiliness and shrinks pores and reduces shininess. Anti inflammatory and anti bacterial, prevents further blemishes and speeds up healing processes.

Sepicontrol A5 – anti bacterial, protects against free radicals and prevents lipid peroxidation.

Pore-reductyl - anti-inflammatory, astringing and tightening effect.

Nio-sebactive - reduces sebum production and shininess.

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Renew & RepairNight Treatment Gel for treatment of blemishes. Boosts cell regeneration. Non irritation, anti bacterial, prevents further breakouts. Leaves the skin even toned.


Salicylic acid - removes dead cells, rids the skin of excessive oil and bacteria.

Perfection peptide - enhanced skin renewal & hydration, balances the desquamation process.

Stable vitamin C -antioxidant, reduces inflammation and irritation, boosts collagen production.

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Soothe &Regulate MaskBalances sebum secretion and excretion. Anti bacterial. Prevents recurrence of comedones, soothes irritation and redness

BSASM - anti inflammatory, anti bacterial, antioxidative.Seboreductyl - Tasman pepper extract – immediate soothing action, comforts and calms the skin. Antioxidant and anti inflammatory properties.

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Scrub & Smooth ExfoliatorGentle, creamy scrub, removes dirt and oil residue from the depth of pores, leaving the skin even-toned and without excessive shine.

Apricot beads – provide excellent exfoliation.

Liquorice & citrus extracts – lightening agents with anti oxidant and soothing properties.

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Correct & Prevent GelDrying gel for topical use. Significantly diminishes the visibility of blemishes and prevents recurrence of comedones. Boosts regeneration and improves texture.

Salicylic acid - removes dead cells, rids the skin of excessive oil and bacteria.


Marine C Thiopeptide - anti inflammatory and anti bacterial. Reduces incidence of comedones and speeds up the healing process.

Sulfur - controls sebum production while absorbing excessive oil.

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Cover & Shield CreamLightweight cover cream conceals blemishes and redness, leaving the skin uniform and even toned. Protects against environmental damage, fights free radicals and speeds up healing processes.

Zinc oxide – calms irritated, red skin and provides physical protection against damaging sun rays.

Bisabolol- anti inflammatory and soothing.

Kalpariane - free radicals scavenger, promotes synthesis of HA, collagen and elastin.

Camouflage – conceals imperfections.

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Hydrate & Restore SerumLightweight serum enriched with moisturizers, regenerates and rejuvenates. Prevents water loss and improves the water reservoir, leaving the skin comfortable and smooth.

HA – preserves optimal hydration, improves the skin’s water retaining properties and increases collagen synthesis.

Hygroplex - effective moisturizer adapted to the skin’s water binding capacity.

Expert moist – moisturizes, improves penetration and prevents TEWL.

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Mattify & Protect Cream SPF 15Lightweight cream enriched with moisturizers provides prolonged protection against sun and environmental damage. Boosts natural regeneration and eliminates excessive shininess

Kollaren – biomimetic peptide stimulates the production of the ECM components (collagen I & III, fibronectin, elastin & laminin).Help increase skin firmness,improves tissue renewal & speeds up healing.

Pentavitin – complex of nutrients and moisturizers

UVA+UVF sun filters – wide spectrum sun filters

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Extract & Refine Peel –Off MaskRemoves blackheads and opens clogged pores while absorbing excess oil. Protects and leaves the skin clean and refreshed. VC-PMG - vitamin C - antioxidant, reduces inflammation and irritation, boosts collagen production.

BSASM - anti inflammatory, anti bacterial, antioxidative.

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Moist & IlluminateEye TreatmentConsolidates the contour of the eyes. Lifts the upper eyelid and diminishes crow’s feet wrinkles. Strengthens dermal structure by boosting collagen synthesis.Fades dark circles and puffiness while calming and moisturizingCentheal- anti inflammatory effect. Beautifeye – antiaging, diminishes crow’s feet wrinkles, strengthens dermal structure, reduces dark circles and puffiness. Aquaderm &HA –preserve optimal hydration, improve skin’s water retaining properties and increase collagen synthesis

the comprehensive treatment for oily and blemished...

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