the changing role of the.pharmacist this course describes the practice of pharmaceutical care is...
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PHARMACEUTICAL CARE PRACTICE
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The changing role of the .pharmacist This course describes the practice of
pharmaceutical care is the new role for the
pharmacist. This course is designed to teach students
the essence of what they will do the rest of
their careers – to provide patient care Although students may choose to apply
their pharmacy education in a number of
areas, they will require an understanding of
the rational decision making process for the
use of drug therapy
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Dispensing pharmacy Pharmaceutical Care
Product business Bring the product
to consumer Decisions focus on
the business Inventory
generates revenue
Available service supports products
Service (people) business
Bring the practitioner to patient
Decisions focus on the patient
Patient care generates revenue
Available products support service
One is not better than the other, but they require different skills, knowledge, personnel, equipment, time, and resources.
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Dispensing pharmacy Pharmaceutical Care
Success measured as # of Rx
Space to display and sell
Records kept for legal purposes
Visits determined by refill supply
Business passive via prescriptions
Success measured as patient outcomes
Space organized to meet patient needs
Documentation to provide quality care
Visits determined by patient risk/benefit
Practice grows via patient recruitment
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Direct patient care The patient makes the final decision as to if
and how he/she will take medications every
day
The pharmaceutical care practitioner has a
brief period of time to influence (positively)
how the patient uses medications
The practitioner is expected to follow-up with
the patient to determine if their care plan had a
positive, negative, or no impact.
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SELF CARE
Practitioner Practitioner
AssessmentCare Plan
Follow-upEvaluation
Direct patient care
Patient
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Pharmaceutical Care in Health Care Primary
FocusKnowledge
Base
Responsibility in the drug use process
Medical Care
Diagnosisand
Treatment of the patient’s
disease
Pathophysiology Prescribing
Nursing Care
Giving care to the whole
patient during the cure or treatment
Biological, psychological,
social, or spiritual human
responses
Drug administration
PharmaceuticalCare
Identifying and meeting a patient’s
drug-related needs
Pharmacotherapy
Identification, prevention,
and resolution of drug therapy
problems
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Pharmaceutical care PC is a professional practice that has evolved
from many years of research and development.
PC is designed to complement existing patient
care practices to make drug therapy more
effective and safe.
This practitioner is not intended to replace the
physician, the dispensing pharmacist, or any
other health care practitioner.
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Pharmaceutical care Definition:
Pharmaceutical care is a patient-
centered practice in which the
practitioner assumes responsibility
for a patient's drug-related needs
and is held accountable for this
commitment.
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Pharmaceutical care It is taking responsibility for ensuring that all of
a patient’s medications are appropriately
indicated, effective, as safe as possible, and
that the patient is able and willing to take them
as intended.
This is accomplished by assessing all the
patient’s drug-related needs in order to identify
if any drug therapy problems exist.
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Pharmaceutical care Pharmacists accept responsibility for optimizing
all of a patient's drug therapy, regardless of the
source (prescription, nonprescription, alternative,
or traditional medicines), to achieve better
patient outcomes and to improve the quality of
each patient's life.
With the patient's cooperation and in
coordination with the patient's other health care
providers.
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Why do we need PC An increase in the complexity of drug
therapy;
An increase in self-care through
alternative and complementary
medicine;
A high level of drug-related morbidity
and mortality which results in significant
human and financial costs.
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Why do we need PC Multiple practitioners writing prescriptions
for a single patient, often without
coordination and communication;
The large number of medications and
overwhelming amount of drug information
presently available to patients;
Patients playing a more active role in the
selection and use of medications;
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Pharmaceutical care as a generalist practice
The PC practitioner assesses all of a
patient's medications, medical conditions,
and outcome parameters, not just those
chosen by disease state, drug action, or
quantity of medications consumed
PC is applicable in all patient care practice
settings including ambulatory, long-term
care, hospital, and clinic settings
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Pharmacits's responsibility
Assure that the goals of therapy are
achieved by
developing a care plan for each medical
condition
by conducting follow-up evaluations at
appropriate times.
preventing drug therapy problems
whenever possible
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Pharmaceutical care The key components of this
description include the PRACTITIONER this individual must posses EXPERT
KNOWLEDGE in the area of PHARMACOTHERAPY
Must apply this knowledge to the benefit of a patient by meeting that patient’s drug-related needs, which BENEFITS the PATIENT.
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The language of practice
General terms such as assessment, care
plan, and follow-up evaluation
Unique terminology drug therapy problem,
medication experience, and drug-related
needs
Synonymous
Practitioner and clinician
Drug therapy and pharmacotherapy
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Practitioner requirements to practice
• Philosophy of practice• Therapeutic relationship with patients• An understanding of the patient’s medication
experience• Rational thought process
-pharmacotherapy workup and drug therapy problems• Patient care process• Documentation system• Reimbursement system
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Philosophy of practice
A set of values that guides behaviors
associated with a professional practice
Helps the practitioner determine what
is important and how to set priorities
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Philosophy of practice
Represents what “should” be done
Describes what is done in the areas of
minimizing drug-related morbidity and
mortality (social obligation) and ensuring
that individual patients are receiving
drug therapies that are appropriately
indicated, effective, safe, and convenient
(patient-specific)
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The therapeutic relationship A therapeutic relationship develops when
you take care of a patient.
The therapeutic relationship is different
than a “personal relationship”, or a
“business relationship”.
The stronger and more positive that the
therapeutic relationship is, the more
likely that positive outcomes can occur
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Characteristicsof the therapeutic relationship
Mutual respect Trust Open communication Cooperation Mutual decision making
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Components of the medication experience
The patient’s description of the medication experience
The medication history
The current medication record
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The medication experience The medication experience includes
more technical aspects as well
The patient's current medications
Social drug use, immunizations
Allergies, alerts, and medication history.
It is usually easier to deal with this
aspect of the medication experience
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The medication experience the patient's beliefs, perceptions,
understandings, attitudes, and behaviors
about drug therapy.
The factors that will most directly
influence the patient's decisions about
whether to take a medication or not, how
much of the medication to take, and how
to take the medication.
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The medication experience Patients come with their own
medication experience.
The more you know about the
patient's medication experience,
the more likely you are to have a
lasting and positive influence on it.
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Steps in the patient care process. The practitioner uses a rational
decision-making process called the Pharmacotherapy Workup to:Make an assessment of the patient's drug-
related needs
Identify drug therapy problems,
Develop a care plan
Conduct follow-up evaluations to ensure that all drug therapies are effective and safe.
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The Patient's Drug-Related NeedsThe medication is appropriate
There is a clinical indication for each medication All of the patient's medical conditions that can benefit from drug therapy have been identified.
The medication is effective
The most effective drug product is being used.The dosage of the medication is sufficient to achieve the goals of therapy.
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The Patient's Drug-Related Needs
The medication is safe
There are no adverse drug reactions being experienced.
There are no signs of toxicity.
The patient is compliant
The patient is willing and able to take the medications as intended.
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Indication Drug product Dosage regimen Outcomes
Safety
Drug Therapy ProblemUnnecessary drug therapy
Needs additional drug therapy
Drug Therapy ProblemIneffective drug
Adverse drug reaction
Drug Therapy ProblemDosage too lowDosage too high
Drug Therapy ProblemNoncompliance
Effectiveness
Structure of the Pharmacotherapy Workup
• In order for a practitioner to evaluate the effectiveness and safety of a patient’s drug therapy he must understand all the steps of the steps above.
• Drug therapy problems can occur anywhere in the patient’s drug use process
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The pharmacotherapy workup
a structured, rational thought process for making clinical decisions
a systematic thought process to assess the needs of a patient, identify and resolve problems, and prevent problems from occurring
Requires a unique knowledge base and set of clinical skills
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The pharmacotherapy workup
Unique knowledge base is focused
on pharmacology,
pharmacotherapy, and
pharmaceutical care practice.
The practitioner identifies, resolves,
and prevents drug therapy
problems.
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The pharmacotherapy workup
A logical thought process that guides work and decisions as the clinician assesses the patient's drug-related needs and identifies drug therapy problems
It organizes the interventions that need to be made on the patient's behalf.
It establishes appropriate parameters to evaluate at follow-up.
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The pharmacotherapy workup
consists of an ordered series of decisions
that allow the practitioner to determine
whether drug therapy problems exist in any
category:
indication, effectiveness, safety, or
compliance
The Pharmacotherapy Workup can be
applied to help all types of patients, with all
types of diseases, with any type of drug
therapy
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The pharmacotherapy workup
asking a standard series of questions,
constantly generating a set of hypotheses,
continuously searching for cues that reject
or accept these hypotheses,
Eliciting more information,
Integrating all of this with existing
knowledge to decide on the best
pharmacotherapy for the patient
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PW: the questions
Are Always Generated as a Response
to Two Basic Questions
Is the patient's problem caused by drug therapy?
Can the patient's problem be treated with drug
therapy?
The pharmacist’s approach is that drug
therapy is the cause of or cure for the
problem
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The patient care process
Establish a therapeutic relationship
What does my patient want and
need?
What am I going to do
for my patient?
How will we know if it is working?
Continuous Follow-up
ASSESSMENT CARE PLAN EVALUATION
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The patient care process
all highly dependent upon each other.
completion of all steps is necessary The process is continuous and
occurs over multiple patient visits Each step of the process depends
on the previous step having been completed well
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The patient care process
Assessment
the patient,
his/her medical problems,
drug therapies
→ leading to drug therapy problem
identification
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The patient care process
The initial assessment, drug therapy
problem identification, and care
planning occur at the first encounter
with each patient
Follow-up evaluations and additional
adjustments to drug therapy occur at
subsequent patient encounters.
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The patient care process
The Pharmacotherapy Workup
describes all the work that you do
mentally while the patient care
process describes the work that
you do physically.
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Activities and Responsibilities in the Patient Care Process
Assessment Meet the patient Establish the therapeutic relationship
Elicit relevant information from the patient
Determine who your patient is as an individual by learning about the reason for the encounter, the patient's demographics, medication experience, and other clinical information
Make rational drug therapy decisions using the Pharmacotherapy Workup
Determine whether the patient's drug-related needs are being met (indication, effectiveness, safety, compliance), identify drug therapy problems
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Activities and Responsibilities in the Patient Care ProcessCare plan Establish goals of therapy Negotiate and agree upon endpoints and
timeframe for pharmacotherapies with the patient
Select appropriate interventions for:
resolution of drug therapy problems
achievement of goals of therapy
prevention of drug therapy problems.
Consider therapeutic alternatives
Select patient-specific pharmacotherapy
Consider nondrug interventions
Educate patient
Schedule a follow-up evaluation Establish a schedule that is clinically appropriate and convenient for the patient
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Activities and Responsibilities in the Patient Care Process
Follow-up evaluation
Elicit clinical and/or lab evidence of actual patient outcomes and compare them to the goals of therapy to determine the effectiveness of drug therapy
Evaluate effectiveness of pharmacotherapy
Elicit clinical and/or lab evidence of adverse effects to determine safety of drug therapy
Evaluate safety of pharmacotherapy
Determine patient compliance
Document clinical status and any changes in pharmacotherapy that are required
Make a judgment as to the clinical status of the patient's condition being managed with drug therapy
Assess patient for any new drug therapy problems
Identify any new drug therapy problems and their cause
Schedule the next follow-up evaluation
Provide continuous care
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AssessmentThe purpose is
(1) To understand the patient well enough to
make rational drug therapy decisions with
and for him/her
(2) To determine if the patient's drug therapy is
appropriate, effective, and safe, and to
determine if the patient is compliant with
his/her medications
(3) To identify drug therapy problems
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AssessmentThe information required
patient data (demographic information,
medication experience)
disease data (current medical conditions,
medical history, nutritional status, review of
systems)
drug data (current medications, past
medication use, social drug use,
immunizations, allergies, and alerts).
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Assessment
The two major activities that occur
during the assessment are:
Eliciting information from the patient
Making clinical decisions about the
patient's medications and meeting
his/her drug-related needs or drug
therapy problems.
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Assessment
Involves:
discussing the patient's medication
experience.
The sum of all the events in a patient's
life that involve medication use.
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Identifying drug therapy problems undesirable events or risks experienced by
the patient that involve or are suspected to
involve drug therapy and that inhibit or
delay him/her from achieving the desired
goals of therapy.
These problems are identified during the
assessment process, so that they can be
resolved through individualized changes in
the patient's drug therapy regimens.
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Identifying drug therapy problems
The Process Used to Identify Whether a
Patient has a Drug Therapy Problem
requires a
Continuous Assessment of 4 Logical
Questions
1. Does the patient have an indication for
each of his/her drug therapies, and is each
of the patient's indications being treated
with drug therapy?
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Identifying drug therapy problems
2. Are these drug therapies effective for
his/her medical condition?
3. Are the drug therapies as safe as
possible?
4. Is the patient able and willing to
comply with the drug therapies as
instructed?
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CategorizationFirst step
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Categories of Drug Therapy ProblemsDescription of the Problem Drug Therapy Problem
The drug therapy is unnecessary because the patient does not have a clinical indication at this time.
Unnecessary drug therapy
Additional drug therapy is required to treat or prevent a medical condition.
Needs additional drug therapy
The drug product is not effective at producing the desired response.
Ineffective drug
The dosage is too low to produce the desired response.
Dosage too low
The drug is causing an adverse reaction.
Adverse drug reaction
The dosage is too high resulting in undesirable effects.
Dosage too high
The patient is not able or willing to take the drug regimen appropriately.
Noncompliance
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IdentificationSecond Step
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Identifying drug therapy
Identify the cause for each drug therapy
problem.
When multiple drug therapy problems exist, they
need to be prioritized
The order of priority is based on the patient's
views regarding which one is causing the most
concern, and the preferences he/she has toward
addressing the problem
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Identifying drug therapy
Final outcome:
the description and prioritization of the
drug therapy problem(s) to be resolved
through specific interventions in the
care plan.
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Care plan development
The purpose
To organize all of the work agreed
upon by the practitioner and the
patient to achieve the goals of
therapy.
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Care plan development
The requirments
Interventions to resolve drug
therapy problems
Interventions to meet these goals
Interventions to prevent new drug
therapy problems from developing.
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Care plan development
Constructing care plans is done in
collaboration with the patient and other
health care practitioners providing care to
the patient.
Care plans are organized by medical
condition
A separate care plan is constructed for each
condition or illness
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Care plan development
Involves three steps:
1. Establishing goals of therapy
2. Selecting appropriate
individualized interventions
3. Scheduling the next follow-up
evaluation.
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Establish goals of therapy
Goals consist of a parameter, a value, and a timeframe.
Goals guide all subsequent decisions, actions, interventions, and patient education.
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Establish goals of therapy
Goals Must be explicitly statedconsistent with the patient's
preferences and desiresclinically soundobservable or measurable in a stated
timeframe.understood and agreed upon by
practitioner and patient.
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Interventions
They are designed to:
Resolve drug therapy problems
Achieve the stated goals of therapy
Prevent new drug therapy problems
from developing
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InterventionsThey are designed to:
Resolve drug therapy problems
takes precedence within the care plan
because goals of therapy cannot be achieved
until patient's drug therapy problems are
resolved
Achieve the stated goals of therapy
Prevent new drug therapy problems from
developing
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InterventionsThey are designed to: Resolve drug therapy problems
Achieve the stated goals of therapyinclude changes in drug therapy regimens and
individualized patient instructions. E.g patient education or instructions as to the
optimal use of medications, related technology, and/or diet and exercise to increase the probability of success with the medication regimen.
prevent new drug therapy problems from developing
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InterventionsThey are designed to: Resolve drug therapy problems Achieve the stated goals of therapy Prevent new drug therapy problems
from developingespecially important for patients who
have a higher than normal probability of developing a drug therapy problem due to some identified risk factor(s).
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Follow-up evaluation schedule the follow-up evaluation to
determine the outcomes of drug therapy. If there are multiple care plans, the
schedules for the follow-up evaluations must be coordinated
During the follow-up evaluation,The results of care plan actions are judged as
to their positive or negative impact on the patient.
.
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Follow-up evaluation
The purpose
To determine the actual outcomes of drug
therapy for the patient
Compare these results with the intended goals of
therapy
Determine the effectiveness and safety of
pharmacotherapy,
Evaluate patient compliance
Establish the current status of the patient.
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Follow-up evaluation
The specific activities performed
Observe or measure positive from drug
therapies (effectiveness).
Observe or measure any undesirable effects
that were caused by a drug therapy (safety).
Determine the actual dosage of medication the
patient is taking that is producing the results
observed (compliance).
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Follow-up evaluation
The specific activities performed
Make a clinical judgement of the status of
the patient's medical condition or illness
being managed with drug therapy
(outcomes).
Reassess the patient to determine if
he/she developed any new drug therapy
problems.
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Follow-up evaluation
Data to evaluate effectiveness
Improvement or reduction of the signs
or symptoms of the patient's medical
condition or illness.
the extent to which abnormal
laboratory test results have returned to
within the desired or normal range.
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Follow-up evaluation
Data to evaluate the safety
Evaluation of unintended
pharmacological effects (side
effects) of the patient's drug therapy.
if lab tests have become dangerously
abnormal due to drug therapy.
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Follow-up evaluation It is important to determine patient
compliance at each follow-up
evaluation, Because both effectiveness
and safety are evaluated based upon
the drug dosages that the patient has
actually taken.
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Follow-up evaluationClinical judgment about the outcomes At each evaluation the status might be resolved,
stable, improved, partially improved, unimproved, worsened, or failed.
Each term contains two items of important information: The patient's present condition What was done to the drug therapy in response to the
patient's condition.
This clinical judgment is recorded and compared to the status at each evaluation to determine if drug therapies are helping the patient meet the desired goals.
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Documentation in practice As pharmacotherapy and medical
services become more complex, creating an effective record of all decisions made concerning the patient's drug therapies and the outcomes of those decisions is essential.
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Documentation in practice Comprehensive documentation is
required and includes patient's clinical informationdrug therapy problemsa comprehensive medication recordgoals of therapyevidence of effectiveness and safety of
pharmacotherapies at every follow-up visit
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Reasons to document
1. Provide quality patient care2. Manage the practice3. Liability issues4. Evaluate performance5. Justify professional role6. Reimbursement
NO DOCUMENTATION MEANS YOU DID NOT DO IT!!
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Requirements for the pharmaceutical care practitioner Understand your responsibilities. Develop a therapeutic relationship with each patient. Apply the Pharmacotherapy Workup to make rational
drug therapy decisions. Learn the patient care process. Acquire an appropriate pharmacotherapeutic
knowledge base. Develop clinical skills. Understand practice standards and ethical
considerations. Document all care provided
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Practice Results
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Key Points A database of 20,761 patients who received
pharmaceutical care during 59,361 patient
encounters has been established over the past
10 years.
A sample of 5136 was selected and evaluated.
patients <65 years (n = 3064), had an average
of 3 medical conditions with an average of 5
drug therapies.
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Frequency of patients by age.
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Frequency of patients by number of medical conditions
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Key Points Patients >65 years (n = 2072), had an average
of 5 medical conditions being treated with 7
medications.
34% of the younger patients had a drug therapy
problem, while 54% of the older patients had ≥
1 drug therapy problems identified by the
clinician at the first pharmaceutical care visit.
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Key Points
The most common drug therapy
problem, in both groups, was the
need for additional drug therapy,
followed by dosages too low and then
patient compliance problems.
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Key Points
The decisions made by
pharmaceutical care practitioners
have been found to be clinically
credible based on the evaluations and
comments of peer-reviewed panels.
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Key Points
Pharmaceutical care practitioners
resolve almost 80% of drug therapy
problems directly with the patient.
Practitioners were able to produce
positive patient outcomes in 90% of
patients, regardless of the patient's age,
medical conditions, or type of drug
therapy problem.
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Key Points
Pharmaceutical care practice saves
patients and the health care system a
significant amount of money and
produces a positive savings to cost
ratio
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MOST FREQUENT INDICATIONS FOR DRUG
THERAPY(N = 26,238 Patient Encounters)
1. HYPERTENSION2. HYPERLIPIDEMIA3. DIABETES4. OSTEOPORSIS 5. VITAMIN/DIETARY SUPPLEMENT
These 10 conditions represent 50% of all indications for drug therapy
6. ALLERGIC RHINITIS7. ESOPHAGITIS8. DEPRESSION9. MENOPAUSAL SYMPTOMS10. ARTHRITIS PAIN
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DRUG THERAPY PROBLEMS (DTP) (N =26,238 Patient Encounters)
Unnecessary Drug Therapy 6 %
Needs Additional Drug Therapy 28 %
Ineffective Drug 8%
Dosage Too Low 20 %
Adverse Drug Reaction 14 %
Dosage Too High 5 %
Noncompliance 19 %
Total 100%
Percent
Indication
Effectiveness
Safety
Compliance
34%
28%
19%
19%
Table 7-6
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Drug therapy problems by category.
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Table 2-13 Type of Drug Therapy Problem—Needs Additional
Drug Therapy
Cause of the problem Patients < 65 yrs olda
Patients 65 yrs oldb
Medical condition requires the initiation of drug therapy
235 (40.1%) 225 (34.9%)
Preventive drug therapy is required to reduce the risk of developing a new condition
228 (38.9%) 274 (42.6%)
Medical condition requires additional drug therapy to attain synergistic or additive effects
123 (21.0%) 145 (22.5%)
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Table 2-19 Most Common Drug Therapy Problems and
Associated Medical Conditions
Patients < 65 yrs old Patients 65 yrs old
Diabetes Needs additional drug therapy
Arthritis Needs additional drug therapy
Depression Needs additional drug therapy
Arthritis Dosage too low
Asthma Needs additional drug therapy
Hypertension Needs additional drug therapy
Asthma Dosage too low Anxiety Needs additional drug therapy
Menopausal symptoms
Needs additional drug therapy
Hyperlipidemia Needs additional drug therapy
Hypertension Needs additional drug therapy
Hypertension Dosage too low
Allergic rhinitis Needs additional drug therapy
Arthritis Adverse drug reaction
Diabetes Dosage too low Arthritis Noncompliance
Hyperlipidemia Needs additional drug therapy
Ischemic heart disease
Needs additional drug therapy
Allergic rhinitis Dosage too low Diabetes Dosage too low
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PRIMARY METHOD OF RESOLUTIONOF DRUG THERAPY PROBLEMS
Patient(79%)
Physician(19%)
Protocol Carrier
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Table 2-24 Interventions Made to Resolve Drug Therapy Problems
Patients < 65 years Patients 65 year
% of interventions %of interventionRequired patient intervention only
Initiate new drug therapy 358 451Change drug product 58 81
Change dosage regimen 293 352Discontinue drug therapy 129 138
Initiate laboratory test monitoring
126 204
Education beyond OBRA 330 430Provided medication reminder
device43 54
Removed patient barrier 126 131Other 209 59Total 1672 (77.6%) 1905( 81.7%)
Required protocol/carrier interventionInitiate new drug therapy 4 0
Change drug product 6 1Change dosage regimen 4 0Discontinue drug therapy 1 4
Other 8 1Total 23 (1.1%) 6( 0.2%)
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IMPACT OF PHARMACEUTICAL CARE
PRACTICE Resolution of drug therapy problems with
Physiciansinitiate new drug therapy
31 %change drug dosage regimens 23 %change drug product
15 % discontinue drug therapy
15 %laboratory monitoring initiated10% other 6%
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Change in Clinical Status at Follow-up Evaluation4492 Patients and 10,485 Medical Conditions
Condition Improvedor
Remained the Same(84 %)
Condition Declined(16 %)
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Clinical Outcomes
84% of the medical conditions requiring drug therapy, which were not already stable at the
time of the first pharmaceutical care encounter, improved
(69%) or remained the same(15%) through the
provision of pharmaceutical care.