The Cerebral Perfusion Index

(CPI):

Developing a Novel Model of Cerebral

Perfusion in the Intensive Care Unit

Jasmine Khan

MD/PhD Student

Queen’s University

Cerebral Perfusion Monitoring Today

● Functional Magnetic Resonance Imaging (fMRI)

● Xenon-enhanced Computed Tomography (XeCT)

● CT Perfusion Monitoring

● Transcranial Doppler (TCD)

● Intracranial Pressure (ICP) Monitoring

● Near-infrared Spectroscopy (NIRS)

Non-invasive ContinuousTool

Wood et al., 2017 Adapted from Scheeran et al., 2019Wood et al., 2017 Adapted from Scheeran et al., 2019

rSO

2(%

)How can we use pre-existing tools to provide a more

comprehensive view of cerebral perfusion?

CPI

Regional Cerebral

Oxygenation (rSO2)

Time spent with disturbed

cerebral autoregulation

Time + distance away from

optimal blood pressure (MAPopt)

Acknowledgements

● Dr. Gord Boyd

● Dr. Michael Wood

● Dr. Kevin Lee

● Miranda Hunt

● Tracy Boyd

● Dr. David Maslove

● Dr. John Muscedere

● Dr. Stephen Scott

● Dr. Jill Jacobson

● Dr. Ian Ball

● Dr. Marat Slessarev

● Eileen Campbell

● Athena Ovsenek

● Dr. Shane English

● Rebecca Porteous

● Irene Watpool

● Maya Halevy

Supplementary- Cerebral Autoregulation Curve

Supplementary- Determining MAPopt

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