the cardiovascular system entertainment group presents: blood the musical human a & p j.allen...
TRANSCRIPT
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The Cardiovascular System Entertainment Group Presents:
BLOODThe Musical
Human A & PJ. Allen
2009
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Components of the CV System BLOOD
BLOOD VESSELS
HEART
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Immunity
Regulates: pH, body temp, water content
of cells
Clotting
Transports Oxygen,
Carbon Dioxide, nutrients, heat,
waste, and hormones
BLOOD
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Blood “Stats” Comprises ___% of body weight pH between _____and ________
Acidosis---pH falls below Alkalosis—pH rises above
Denser than ________and 5x more __________ Volume
4-5 L for women (_____gal) 5-6 L for men (_____gal)
Temperature 100.4 FQ) Why not 98.6 F?A) Movement and friction generates heat
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Components of Blood _____% Plasma
92% of plasma is made up of ______
8% are other substances such as _______, _______, _______
____% Formed Elements 99 % of F. E. are ________ 1% called the _______
_______are __________ and ___________, which are involved in __________
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Related Terms The study of blood,
blood forming tissues, and blood disorders is called ___________
Hematocrit (Hct) Measures RBC % in
blood sample Avg. female Hct is
38-45 Avg. male Hct is 40-
54 CBC—most commonly
ordered blood test Measures RBC’s,
WBC’s, platelets
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DO WE REALLY HAVE BLUE BLOOD: Your *blood* does not ever *look* blue.
The blue things you see under your skin are veins. Veins are really whitish in color but because the blood is dark and the skin diffuses the light, the veins *look* blue.
So when you bleed the blue blood does not meet the air and turn red ?
No, the dark red blood *may* pick up a little oxygen and brighten up a slight bit, but your blood is *never* blue
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RED BLOOD CELLS• Called ___________, and produced by the
process of _______________. What is erythropoietin? _________________________________________
__________________• Shaped like a ___________ or a disk• Have no nuclei and few organelles• Do not use ___________for energy• Contains ______________ (red pigment)
– Composed of ___________groups throughout, with a centralized_______________ atom that binds to __________________
• Average life span of RBC’s is ________________• 1 RBC contains ______________hemoglobin
molecules that contain __________________ molecules of Oxygen!!!
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White Blood CellsSTATS• Called______________________, are
produced by the lymph nodes and bone marrow to fight off invaders. (In children, __________gland also produces them)
• unlike RBC's, contain ____________and ______________ but no ___________
• detect ____________ __________by chemicals released from injured area
• life span: few __________to few ____________
• normal count is between __________& _____________ per drop, but can reach a level of _________________in Leukemia patients (WBC cancer).
• ______________can also spike WBC count initially to around _______________
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TYPES OF WBC’S• GRANULAR LEUKOCYTES--
contain chemical filled vesicles which phagocytize or engulf invaders
1. Neutrophils--most numerous, and are first to respond to bacteria or invaders ex) PUS!!!
2. Eosinophils--respond to allergic reactions, involved in inflammatory responses, and are specific to parasitic worms such as tapeworms, roundworms, and hookworms.
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TAPEWORMS!!!
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WHITE BLOOD CELLS
GRANULAR LEUKOCYTES3. BASOPHILS are the rarest of the three, and are also involved in inflammation, and release HEPARIN An anticoagulant –anti -clotting used for heart/vascular patients and during open heart surgery.• also release histamine, which is a bronchiole constrictor and vasodilator. Blood rushes to the allergen affected area making it
more difficult to breathe.
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White blood cells
• Agranular leukocytes1. Lymphocytes-
vaccinations boost the number of these.
– Include:– T-CELLS-- which aid
in fighting cancer, viruses, and fungi
– B-CELLS--- which inactivate bacterial toxins
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WHITE BLOOD CELLS
AGRANULAR LEUKOCYTES
2. MONOCYTES
last responders are larger in numbers, and bring wandering macrophages which clean up debris in the affected area by phagocytosis
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PLATELETS
• are cell fragments that form plugs in the injured vessel, and also promote clotting (aka coagulation).
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Diseases of rbc’s
• Hemachromatosis– Body absorbs more
Iron than it needs– Untreated, may cause
arthritis, liver disease, diabetes
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anemia
• Disease in which the oxygen carrying capacity of blood is reduced to a decrease in hemoglobin– Pale, tired, cold
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Sickle cell anemia
• Half moon shaped blood cells
• cause circulation problems, very painful
• Genetic, prevalent in african americans
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hdn• Hemolytic disease of the newborn
– Mother’s blood is Rh negative, fetus’s blood is Rh positive– Mother’s blood will make anti-rh antibodies to attack fetal blood– Can receive an injection to prevent this from happening
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blood types•RBC’s have _________________, or surface proteins, which determine blood type. There are two types of antigens: _________&_________. There are 4 major blood types: A, B, AB, & O. Our blood plasma produces _____________against blood that is not our own, except for the ________blood type.
BLOOD TYPE
ANTIGEN ANTIBODIESPRODUCED
CANRECEIVE
FROM
CANDONATE
TO
ABO AGGLUTINATION(CLUMPING)
ANTI-A ANTI-B
WELLPLATES A B
%
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Rh Factor • First discovered in the
Rhesus Monkey• If a person has the protein in
their blood, they are Rh +• If a person does not have it,
they are Rh –• To determine the frequency
of a blood type:
Ex) A+ (A) (+) 100 x 100
42 85
2.4 x 1.8
Therefore, 1 in 4.3 people have A+ blood