the big 4 carbohydrates lipids proteins nucleic acids um…..what’s up doc?
TRANSCRIPT
The Big 4
• Carbohydrates• Lipids• Proteins• Nucleic Acids
Um…..What’s up Doc?
Monomers/Polymers
• Monomers: a single unit of a macromolecule
• Polymers: more than one unit of a macromolecule – Linked by covalent bonds
Monomers, Polymers and Macromolecules
CARBOHYDRATES
SUGARSANDSTARCHES
CARBOHYDRATES
Three Types of Carbohydrates
POLYSACCHARIDE(have 3 or more sugar units)
DISACCHARIDES(have 2 sugar units)
MONOSACCHARIDES(have 1 sugar unit)
Structure• Carbohydrates are
composed of carbon (C), hydrogen (H), and oxygen (O) atoms in approximately a 1:2:1 ratio.
MONOSACCHARIDES
Simple Sugars• Simple sugars, made of a single sugar unit.• Examples: Glucose, Galactose, Fructose.• Glucose is the most common simple sugar
Glucose• Glucose, the main sugar in your blood.
• Glucose has 6 carbon atoms, 12 hydrogen atoms, and 6 oxygen atoms.
DISACCHARIDES•Made of two simple sugars or
monosaccharides.•Examples: SUCROSE = Glucose + Fructose (table sugar) MALTOSE = Glucose + Glucose (malt sugar) LACTOSE = Glucose +
Galactose (milk sugar)
POLYSACCHARIDES•Polysaccharides are made of three
or more simple sugars or monosaccharides.
•They usually consist of thousands of connected monosaccharides.
•Examples: starch, cellulose, glycogen.
Complex Carbohydrates Are Often Used to Create Structures
Cellulose is the most abundant macromolecule on earth – and you’re probably wearing it now.
Functions of Carbohydrates
1.Energy source for cells.
2.Provides support for plants.
3.Hard body covering for insects
LIPIDS(FATS)
Characteristics of Lipids
• Lipids are nonpolar organic molecules and, therefore, do not dissolve in water.
Examples
• Examples: bacon fat, vegetable oil, butter, margarine, wax.
Lipids are Hydrophobic Molecules That Exist In Three Primary Forms
Sterol
FatPhospholipid
The Building Blocks of Lipids
GLYCEROL
3
FATTY
ACIDS
Molecular Structure of a Fat
Glycerol• Glycerol is a three-carbon alcohol
molecule usually obtained by the saponification of fats and used as a solvent.
Fatty Acids• Fatty acids are long chains of carbon
atoms with a -COOH group or carboxyl group at the end.
• Examples:
FATTY ACIDS
SATURATED UNSATURATED
Saturated Fatty Acids
• Saturated fatty acids have the maximum possible number of hydrogen atoms (H).
H H H H H H H H H H H O
H C C C C C C C C C C C C OH
H H H H H H H H H H H
Unsaturated Fatty Acids
• Unsaturated fatty acids have double bonds, and therefore fewer hydrogen atoms (H).
H H H H H H H H H H H H H H H H O
H C C C C C C C C C C C C C C C C O H
H H H H H H H H H H H H H H
At a Store Near You
Beginning January 1, 2006, the FDA required that the amount of trans fat be listed on all food labels.
The new line showing levels of trans fat
Solid or Liquid?
• A triglyceride that is solid at room temperature is called FATFAT.
• A triglyceride that is liquid at room temperature is called OILOIL.
Triglycerides• The majority of fat in organisms
consists of one type of polymer of lipids called triglycerides.
• Triglycerides are composed of alcoholalcohol glycerolglycerol and three fatty acidsfatty acids.
Phospholipids• Phospholipids are
made out of
* glycerol,
* 2 fatty acids &
*phosphate group.
• Building block of cell membranes.
Hydrophilic Head Group And Hydrophobic Tails Are The Keys To Phospholipid Function
Phospholipids Form Double-Layered Biological Membranes
Steroids are also Lipids
Note the four ring structure common to all sterols.
Sterols are: 1) essential membrane components and 2) form many hormones.
Sterols As Hormones
Estrogen, testosterone, progesterone, and corticosteriods (cortisol) are all steroid hormones.
Sterols As Hormones
“Designer steroids” are major sporting news where they have been used illegally in track and field, baseball, football and countless other sports.
A heavily muscled Linford Christie who was disqualified from international competition after testing positive for a banned steroid.
Functions of Lipids• Major components of cell membranes.• Insulation.• Protective covering.• Energy storage – fat is stored in animal cells as large lipid droplets.
PROTEINS
Building BlocksSince proteins are LARGE molecules,
they are composed of smaller building blocks – AMINO ACIDSAMINO ACIDS.
•AMINO ACIDS
AMINO ACIDS (AA)There are only 20 different AA
AMINO ACID STRUCTURE
•R group is different in every AA
•Observe different R groups
Models of Amino Acids
CARBON
OXYGEN
HYDROGEN
NITROGEN
PEPTIDE BONDS•Amino acids are joined together by PEPTIDE BONDS.
•Bond forms between the –COOH (carboxyl) group of one AA and the -NH2 of another AA.
H H O H H O H H O H H O
N C C OH + N C C OH N C C N C C+ H2O
H R H R H R R OH
PEPTIDE BOND
How Long Are Proteins?•Proteins are long chains of amino acids with an average of 200 amino acids per chain.
PROTEIN Shapes
HemoglobinHemoglobin – a protein in red blood cells responsible for oxygen transport.
MyoglobinMyoglobin – protein in muscles that serves as storage site for oxygen.
EXAMPLES
TERTIARY STRUCTURE
QUATERNARY STRUCTURE
Functions of Proteins
A. ENERGY SOURCE
B. B. STRUCTURAL COMPONENTSSTRUCTURAL COMPONENTS Following are made out of proteins:
•HAIR
TURTLE
SHELL•SPIDER WEB
•FEATHERS
•NAILS
Strands of the Protein Keratin Create Hair
C. FIGHT INFECTIONS
•FibersFibers in a blood clot and antibodiesantibodies are made out of proteins.
D. ASSIST LIFE PROCESSES•Transports oxygen in red blood cells.
•Aids digestion.
•Enzymes
are proteins.
There are two kinds of nucleic acids, DNA and RNA. •Both are involved in the storage and flow of information from gene to gene product.
DNA
Recently, we’ve learned that RNA also plays important regulatory roles.
Nucleic Acids
Nucleotides Are the Monomers That Create Polymers of DNA and RNA
Nucleotides fuel the cell and coordinate its metabolism.
Nucleotides are Important in Their Own Right
ATP, the cell’s primary energy currency.
Molecules of Life Big Four
Start with water, add lots of small carbon-containing molecules and …….
How do you build a cell?
Use these four major classes of biological molecules.