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THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

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Page 1: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

THE BEST OF SOARDHarvey Sugerman, MD, FACS, FASMBS

Editor-in-ChiefSurgery for Obesity and Related Diseases

Page 2: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

Top 25 Article Requests on ScienceDirect (Jan-Dec 2009)

Review Articles:5/25: 20%Original FLA:

20/25: 80%

Vol. 5: 56%Vol. 4: 32%Vol. 3: 12%

RankVol/Iss

Cover Date Paper Type Article Title Author(s)

Requests for Full-

text Articles

1 4/5 01-Sep-2008

Review article

American Association of Clinical Endocrinologists, The Obesity Society, and American Society for Metabolic&Bariatric Surgery Medical Guidelines for Clinical Practice for the Perioperative Nutritional, Metabolic, and Nonsurgical Support of the Bariatric Surgery tient

Mechanick, J.I.; Kushner, R.F.; Sugerman, H.J.; Gonzalez-Campoy, J.M.; Collazo-Clavell, M.L.; Guven, S.; Spitz, A.F.; Apovian, C.M.; Livingston, E.H.; Brolin, R.; Sarwer, D.B.; Anderson, W.A.; Dixon, J.

484

2 4/3 01-May-2008

Full length article

Review of meta-analytic comparisons of bariatric surgery with a focus on laparoscopic adjustable gastric banding

Cunneen, S.A. 439

3 3/2 01-Mar-2007

Full length article

Laparoscopic adjustable gastric banding versus Roux-en-Y gastric bypass: 5-year results of a prospective randomized trial

Angrisani, L.; Lorenzo, M.; Borrelli, V. 317

4 4/5 01-Sep-2008

Review article

ASMBS Allied Health Nutritional Guidelines for the Surgical Weight Loss Patient

Allied Health Sciences Section Ad Hoc Nutrition Committee; Aills, L.; Blankenship, J.; Buffington, C.; Furtado, M.; Parrott, J.

270

5 5/4 01-Jul-2009 Full length article

The Second International Consensus Summit for Sleeve Gastrectomy, March 19-21, 2009

Gagner, M.; Deitel, M.; Kalberer, T.L.; Erickson, A.L.; Crosby, R.D. 265

6 4/4 01-Jul-2008 Full length article

Postgastric bypass hyperinsulinemic hypoglycemia syndrome: characterization and response to a modified diet

Kellogg, T.A.; Bantle, J.P.; Leslie, D.B.; Redmond, J.B.; Slusarek, B.; Swan, T.; Buchwald, H.; Ikramuddin, S.

262

7 5/5 01-Sep-2009

Full length article

Comparison of weight loss and body composition changes with four surgical procedures

Strain, G.W.; Gagner, M.; Pomp, A.; Dakin, G.; Inabnet, W.B.; Hsieh, J.; Heacock, L.; Christos, P.

255

8 5/2 01-Mar-2009

Full length article National trends in use and outcome of laparoscopic

adjustable gastric bandingHinojosa, M.W.; Varela, J.E.; Parikh, D.; Smith, B.R.; Nguyen, X.M.; Nguyen, N.T. 239

Page 3: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

Top 25 Article Requests on SD, cont.

Rank

Vol/Iss

Cover Date Paper Type Article Title Author(s)Requests

for Full-text Articles

9 3/2 01-Mar-2007 Short communication

Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22-34 kg/m^2: a report of 2 cases

Cohen, R.V.; Schiavon, C.A.; Pinheiro, J.S.; Correa, J.L.; Rubino, F. 233

10 4/5 01-Sep-2008 Full length article

Enoxaparin thromboprophylaxis in gastric bypass patients: extended duration, dose stratification, and antifactor Xa activity

Borkgren-Okonek, M.J.; Hart, R.W.; Pantano, J.E.; Rantis, P.C.; Guske, P.J.; Kane, J.M.; Gordon, N.; Sambol, N.C.

223

11 5/4 01-Jul-2009 Full length article

Effect of sleeve gastrectomy on patients with diabetes mellitus

Rosenthal, R.; Li, X.; Samuel, S.; Martinez, P.; Zheng, C. 222

12 3/2 01-Mar-2007 Full length article

Safety and efficacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery

Longitudinal Assessment of Bariatric Surgery Consortium Writing Group (in alphabetical order); Belle, S.H.; Berk, P.D.; Courcoulas, A.P.; Flum, D.R.; Miles, C.W.; Mitchell, J.E.; Pories, W.J.; Wolfe, B.M.; Yanovski, S.Z.

213

13 5/2 01-Mar-2009 Full length article

Two-year changes in health-related quality of life in gastric bypass patients compared with severely obese controls

Kolotkin, R.L.; Crosby, R.D.; Gress, R.E.; Hunt, S.C.; Adams, T.D. 200

14 4/3 01-May-2008 Review article Pregnancy outcomes after bariatric surgery: maternal, fetal, and infant implications

Abodeely, A.; Roye, G.D.; Harrington, D.T.; Cioffi, W.G. 198

15 5/5 01-Sep-2009 Full length article

Safety and effectiveness of Realize adjustable gastric band: 3-year prospective study in the United States

Phillips, E.; Ponce, J.; Cunneen, S.A.; Bhoyrul, S.; Gomez, E.; Ikramuddin, S.; Jacobs, M.; Kipnes, M.; Martin, L.; Marema, R.T.; Pilcher, J.; Rosenthal, R.; Rubenstein, R.; Teixeira, J.; Trus, T.; Zundel, N.

196

16 5/2 01-Mar-2009 Short communication

Full and durable remission of type 2 diabetes? Through surgery? Pories, W.J.; Dohm, G.L. 192

Page 4: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

Top 25 Article Requests on SD, cont.

Rank Vol/Iss Cover Date Paper Type Article Title Author(s)Requests for

Full-text Articles

17 5/4 01-Jul-2009 Review article Systematic review of sleeve gastrectomy as staging and primary bariatric procedure

Brethauer, S.A.; Hammel, J.P.; Schauer, P.R. 185

18 5/3 01-May-2009 Review article SAGES guideline for clinical application of laparoscopic bariatric surgery SAGES Guidelines Committee 184

19 5/1 01-Jan-2009 Full length article

Updated Bariatric Analysis and Reporting Outcome System (BAROS) Oria, H.E.; Moorehead, M.K. 182

20 5/3 01-May-2009 Full length article

Remission of type 2 diabetes after Roux-en-Y gastric bypass is associated with greater weight loss

Kadera, B.E.; Lum, K.; Grant, J.; Pryor, A.D.; Portenier, D.D.; DeMaria, E.J.

176

21 5/1 01-Jan-2009 Full length article

Effect of laparoscopic Roux-en-Y gastric bypass surgery on hemoglobin A1c levels in diabetic patients: a matched-cohort analysis

Mumme, D.E.; Mathiason, M.A.; Kallies, K.J.; Kothari, S.N. 170

22 4/1 01-Jan-2008 Full length article Complications after laparoscopic sleeve gastrectomy

Lalor, P.F.; Tucker, O.N.; Szomstein, S.; Rosenthal, R.J. 169

23 5/2 01-Mar-2009 Full length article

A rodent model of metabolic surgery for study of type 2 diabetes and positron emission tomography scanning of beta cell mass

Inabnet, W.B.; Milone, L.; Korner, J.; Durak, E.; Ahmed, L.; Pomrantz, J.; Harris, P.E.; Bessler, M.

169

24 4/1 01-Jan-2008 Full length article

First human experience with endoscopically delivered and retrieved duodenal-jejunal bypass sleeve

Rodriguez-Grunert, L.; Galvao Neto, M.P.; Alamo, M.; Ramos, A.C.; Baez, P.B.; Tarnoff, M.

160

25 5/2 01-Mar-2009Full length

article Brief, four-session group CBT reduces binge eating behaviors among bariatric surgery candidates

Ashton, K.; Drerup, M.; Windover, A.; Heinberg, L. 152

Page 5: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

IMPACT FACTOR 3.85#9

Among ALL Surgical Journals

Page 6: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

2007 Laparoscopic adjustable gastric banding versus Roux-en-Y gastric bypass: 5-year results of a prospective randomized trialAngrisani L., Lorenzo M., Borrelli V. 322007 Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22-34 kg/m2: a report of 2 casesCohen R.V., Schiavon C.A., Pinheiro J.S., Correa J.L., Rubino F.212007 Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric bandingKorner J., Bessler M., Inabnet W., Taveras C., Holst J.J.202007 Comparative long-term mortality after laparoscopic adjustable gastric banding versus nonsurgical controlsBusetto L., Enzi G., Mirabelli D., Petroni M.L., Mazza M., Favretti F., Segato G., Chiusolo M., Merletti F., Balzola F.172008 First human experience with endoscopically delivered and retrieved duodenal-jejunal bypass sleeveRodriguez-Grunert L., Galvao Neto M.P., Alamo M., Ramos A.C., Baez P.B., Tarnoff M.162008 Complications after laparoscopic sleeve gastrectomy Lalor P.F., Tucker O.N., Szomstein S., Rosenthal R.J.162007 Obesity surgery mortality risk score: proposal for a clinically useful score to predict mortality risk in patients undergoing gastric bypassDeMaria E.J., Portenier D., Wolfe L. 152007 Is there a benefit to preoperative weight loss in gastric bypass patients? A prospective randomized trialAlami R.S., Morton J.M., Schuster R., Lie J., Sanchez B.R., Peters A., Curet M.J.122007 Safety and effi cacy of bariatric surgery: Longitudinal Assessment of Bariatric Surgery Belle S.H., Berk P.D., Courcoulas A.P., Flum D.R., Miles C.W., Mitchell J.E., Pories W.J., Wolfe B.M., Yanovski S.Z.122007 Natural history of morbid obesity without surgical intervention Sowemimo O.A., Yood S.M., Courtney J., Moore J., Huang M., Ross R., McMillian U., Ojo P., Reinhold R.B.122007 Comparative study between laparoscopic adjustable gastric banding and laparoscopic gastric bypass: single-institution, 5-year experience in bariatric surgeryJan J.C., Hong D., Bardaro S.J., July L.V., Patterson E.J.122007 Intragastric balloon for high-risk super-obese patients: a prospective analysis of effi cacy Spyropoulos C., Katsakoulis E., Mead N., Vagenas K., Kalfarentzos F.112008 Review of meta-analytic comparisons of bariatric surgery with a focus on laparoscopic adjustable gastric bandingCunneen S.A. 102008 Cost-effectiveness analysis of laparoscopic gastric bypass, adjustable gastric banding, and nonoperative weight loss interventionsSalem L., Devlin A., Sullivan S.D., Flum D.R.102008 Predictors of outcome in treatment of morbid obesity by laparoscopic adjustable gastric banding: results of a prospective study of 380 patientsWolnerhanssen B.K., Peters T., Kern B., Schotzau A., Ackermann C., von Flue M., Peterli R.92008 Studies of Swedish adjustable gastric band and Lap-Band: systematic review and meta-analysis Cunneen S.A., Phillips E., Fielding G., Banel D., Estok R., Fahrbach K., Sledge I.92007 Sleeve gastrectomy as a bariatric procedure 92007 Prospective randomized trial of banded versus nonbanded gastric bypass for the super obese: early resultsBessler M., Daud A., Kim T., DiGiorgi M. 92007 Laparoscopic sleeve gastrectomy for morbid obesity: a review Aggarwal S., Kini S.U., Herron D.M. 92007 A two-decade spectrum of revisional bariatric surgery at a tertiary referral center Nesset E.M., Kendrick M.L., Houghton S.G., Mai J.L., Thompson G.B., Que F.G., Thomsen K.M., Larson D.R., Sarr M.G.9

Top 20 Articles by Citations Comprising the 2009 Impact Factor of 3.862

Page 7: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

EDITOR-IN-CHIEF’SBEST OF SOARD CHOICES

Volume 1, 2005– Eid et al. Effective treatment of polycystic ovarian

syndrome with Roux-en-Y gastric bypass. pp. 77-80• 24 women, 57% EWL 1 y, all resumed normal menses

at ~ 3 mos, 12/23 complete, 6 moderate resolution hirsutism at ~ 8 mos, 5 conceptions

– Brechner et al. A graded, evidence-based summary of evidence for bariatric surgery. pp. 430-41

Page 8: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases
Page 9: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD Vol 2, 2006– Alagna et al. Biliopancreatic diversion: long-term effects

on gonadal function in severely obese men. pp. 82-6• 20 men (21-63 y), LH, FSH and total testosterone

significantly increased from subnormal pre-op to normal; estradiol decreased from elevated basal levels to normal

– Gustafson et al. History of sexual abuse among bariatric surgery candidates. pp. 369-74• 16% (17% female, 11.5% male); ↑ binge eating, substance

abuse and hx of psych rx

Page 10: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 2, 2006(con’t)– Sampalis et al. Impact of bariatric surgery on

cardiovascular and musculoskeletal morbidity. pp. 587-91• 62% EWL, significant ↓ diagnosis and rx of above

– Leichman et al. Improvements in systemic metabolism, anthropometrics and left ventricular geometry 3 months after bariatric surgery. pp. 592-9• MRI showed significant ↓ in LV mass, visceral adipose

tissue, CRP and ↑ insulin sensitivity

Page 11: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 2, 2006(Con’t)

– Parikh et al. LAGB for patients with BMI ≤ 35. pp. 518-22• 93 pts Australia, BMI 32.7 to 27.6 at 3 y with 89% f-u,

improved co-morbidities, no mortality

– Salinas et al. Self-expandable metal stents to treat gastric leaks. pp. 146-8• 17 pts (14 males) G-J leak after RYGB, 16 successful, oral

feeding 2-3 days p stent, 5 OR to drain abscess

Page 12: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 2, 2006(Con’t)– Jamal et al. Insurance-mandated preoperative dietary counseling

does not improve outcome and increases dropout rates in patients considering gastric bypass for morbid obesity. pp.122-7• 50% dropout, no difference in success of surgery

– Gibbons et al. Previous weight loss experiences of bariatric surgery candidates: how much have patients dieted prior to surgery? pp. 259-64• 4.7 ± 2.9 prior successful (≥ 10 lbs) + numerous unsuccessful diet

attempts; wt ↑ from 89.4 ± 27.4 kg at time of first diet to 144.5 ± 30.8 kg

Page 13: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases
Page 14: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD:Vol 3, 2007– Busetto et al. Comparative long term mortality after

laparoscopic adjustable gastric binding versus nonsurgical controls. pp. 496-502• 5y 60% < mortality than cohort

– Sowemimo et al. Natural history of morbid obesity without surgical intervention. pp. 73-7• Mortality in 743 after bariatric surgery (165 LTFU) = 2.8% vs.

14.3% no surgery. After adjusting for variables: 82% decreased mortality

Page 15: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 3, 2007(Con’t)• Belle et al. Safety and efficacy of bariatric surgery:

Longitudinal Assessment of bariatric surgery pp. 116-26– 1st paper re. prospective, NIH, multicenter protocol

• DeMaria et al. Obesity surgery mortality risk score: proposal for a clinically useful score to predict mortality risk in patients undergoing bariatric surgery. pp. 134-40– BMI, Male, Htn, PE risk, age: 1 point each– Class A = 0-1, B = 2-3, C = 4-5 points– Mortality: Class A = .31%, B = 1.9%, C = 7.6%

Page 16: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 3, 2007(Con’t)

– Kuruba et al. Bariatric surgery improves urinary incontinence in morbidly obese individuals. pp. 586-91

• 65/201 (65%) surgery candidates (1 male) incontinent

• 38 pts RYGB: 50% severe, 48% moderate, 2% mild

• 50% complete resolution, 37% mild-moderate, 13% severe at ≥ 6 mos postop

• Severity score 5.4±2.3 to 2.3±2.8 (p < .001)

Page 17: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD:Vol 3, 2007(Con’t)• Korner et al. Exaggerated glucagon-like peptide-1 and blunted glucose-

dependent insulinotropic peptide (IP) secretion are associated with RYGB but not AGB. pp. 597-• BG at 60 min < after RYGB than LAGB (70 vs. 83mg/dL)• GLP-1 level 3X after RYGB than LAGB (96 vs. 28pmol/L)• IP level lower after RYGB than LAGB (20 vs. 31pmol/L)

• Hagedorn et al. Does gastric bypass alter alcohol metabolism? pp. 543-8– 5 oz red wine, q 5 min breath analysis– Peak EtOH: 0.08% RYGB vs. 0.05% controls– 0 level: 108 min RYGB vs. 72 min controls– No difference postingestion symptom profile

Page 18: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 3 (Con’t)• Johnson et al. Surgical revision of loop (“mini”) gastric bypass

procedure: multicenter review of complications and conversions to Roux-en-Y gastric bypass. 2007;3:37-41.– 5 med centers, 32 pts: bile reflux 20; GJ leak 3, marginal ulcer 5;

malnutrition 8; weight gain 2

– 21 converted to RYGB; 2 with Braun entero-enterostomy

• Miller KA, Pump A. Use of bioabsorbable reinforcement material in gastric bypass: a prospective randomized clinical trial. 2007;3:417-22– < bleeding (fewer clips, higher Hgb), < OR time

Page 19: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 3, 2007(Con’t)– McCloskey et al. Bariatric surgery improves cardiac function

in morbidly obese patients with severe cardiomyopathy. pp. 503-7• 14 pts (10 men); EF 23±2 to 32±4% at 6 mos

• Preop: 2 Class IV; 6 Class III; 6 Class II

• Postop: 0 Class IV; 2 Class III; 12 Class II

– Dallal et al. Medicare and Medicaid status predicts prolonged length of stay (PLOS) after bariatric surgery. pp. 592-6.• PLOS (≥ 7d) = 3.7%

• Medicare pts 6X and Medicaid 3.2X PLOS

Page 20: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases
Page 21: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD Vol 4

– Christou et al. Bariatric surgery reduces cancer risk in morbidly obese patients. 2008;4:691-7

• < physician/hospital visits vs. controls: 2.0 vs. 8.5%

• < physician/hospital visits for breast cancer

– Keto JL, Kemmeter P. Effect of Center of Excellence requirement by Centers for Medicare and Medicaid Services on practice trends. 2008;4:437-40

• % CMS/Medicaid ↑ from 15/10% 2004/2005 to 31% 2006

• Older (56 vs. 44), > comorbidities (5.1 vs. 3.5), more meds (10.3 vs. 5.6), more prior ops (2.1 vs. 1.3), longer OR times (148 vs. 121 min) than private 3 rd party insured

Page 22: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 4 (Con’t)• Song et al. Association between support group

attendance and weight loss after Roux-en-Y gastric bypass 2008;4:100-3– Significantly > %EWL at 9 (53 vs. 45) and 12 mos (56

vs. 47) in those attending support group

• Arceo-Olaiz et al. Maximal weight loss after banded and unbanded laparoscopic Roux-en-Y gastric bypass: a randomized controlled trial. 2008;4:507-11– No difference at 12 or 24 mos; 1 band removed

Page 23: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol. 4, 2008(Con’t)

• Carbonell et al. Does diabetes affect weight loss after gastric bypass? pp. 441-4– Of 655, DM pts had < %EWL: 67.6 no DM vs. 63.5 diet only vs.

60.5 for oral vs. 53.3 on insulin

• Salem et al. Cost-effectiveness of laparoscopic gastric bypass, adjustable gastric banding, and nonoperative weight loss interventions. pp.26-32– Both men & women, RYGB & LAGB were cost-effective at

<$25,000 for QALY regardless of BMI, adverse outcomes, weight loss or costs. LAGB > RYGB

Page 24: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 4,2008 (Con’t)

• 2 baseline LABS studies:– Relationship of body mass index with demographic and

clinical characteristics in the Longitudinal Assessment of Bariatric Surgery. pp.474-80.

– Physical activity levels of patients undergoing bariatric surgery in the Longitudinal Assessment of Bariatric Surgery. pp. 721-8.

Page 25: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases
Page 26: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5

• ASMBS GUIDELINES AND POSITION STATEMENTS:– Emerging endosurgical interventions for the

treatment of obesity– Detection and prevention of gastrointestinal

leak after gastric bypass including the role of imaging and surgical exploration

Page 27: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5, 2009(Con’t)• Dolce et al. Does liver appearance predict histo-

pathological findings: prospective analysis of routine liver biopsies during bariatric surgery. pp. 323-8– NASH in 23% – 48% with normal liver appearance score had NASH

• Martinez et al. Diagnosis and treatment of megaesophagus after LAGB for morbid obesity. pp.156-9– 5/257; mean time at 32 (24-36) mos; preop manometry nl in 4;

band deflation ineffective; all required band removal

Page 28: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5, 2009(Con’t)

• Mumme et al. Effect of LRYGB on hgbA1c levels in diabetic patients: a matched cohort analysis. pp. 4-10– Matched cohorts: HgbA1c at 3 y: 6.1 vs. 7.8– RYGB decreased insulin/oral agents 84% to 22% at 1 y

• Alexander et al. Improvement and stabilization of chronic kidney disease after gastric bypass. pp.237-– 45 pts with established renal disease before RYGB: 1 GN

completely resolved, 4 pts d/c dialysis – but 2 had to resume, 6 pts had progressive improved function, all ↓ proteinuria

Page 29: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5, 2009(Con’t)

• Ghandi et al. Elective laparoscopy for herald symptoms of mesenteric/internal hernia after L-RYGB. pp. 144-9– 27/702 (3.8%) acute SBO; 15 (55%) internal hernia (IH)– Nearly ALL had prior sx of intermittent SBO– Elective laparoscopy in 9 with intermittent sx; all IH

• Bond et al. Prevalence and degree of sexual dysfunction in a sample of women seeking bariatric surgery. pp. 698-704– 60% female sexual dysfunction

Page 30: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5, 2009(Con’t)

• Miller et al. Physical function improvements after L-RYGB. pp. 530-7– ↓ disability, ↑ mobility within 3 wks, ↑ max muscle

torque/kg within 6 mos after surgery

• Farbris de Souza et al. Six-minute walk test: functional capacity of severely obese before and after bariatric surgery. pp. 540-3– 382±49 m before vs. 468±40 m 7-12 mos after surgery

Page 31: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 5, 2009(Con’t)

• Topart et al. One-year weight loss after primary or revisional RYGB for failed LAGB. pp. 459-62. Revisional RYGB:– Longer OR times: 128±26 vs. 89±15 min– ↑ morbidity– Equivalent 1 y %EWL: 66±28 vs. 70±19

Page 32: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

“Look, Fred, you’re a lousy surgical risk. I know theoperation might save your life, but I can’t do it. It couldwreck my statistics.”

Page 33: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 6, 2010• Smith et al. The relationship between surgeon volume and

adverse outcomes after RYGB in the LABS study. pp. 118-25– > surgeon volume < event rates; continuous variable– each 10 case/y ↑ vol, event rate ↓ 10%

• DiGiorgi et al. Reemergence of diabetes after gastric bypass in patients with mid- to long-term follow-up. pp. 249-53– 10/42 (24%) with improved or remitted DM at ≥ 3 y f/u recurred or

worsened – had > wt regain, > wt loss failure

Page 34: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 6, 2010(Con’t)• Bessler et al. AGB as a revisional procedure after failed RYGB –

intermediate results. pp. 31-5– 22 pts, % EWL from 13.5 to 59.4 at 12 mos (13/20), 53.1 at 24 mos (10/15),

59.3 at 48 mos (7/9)

• Shah et al. Diabetes remission and reduced cardio-vascular risk after RYGB in Asian Indians BMI<35 pp. 332-8– 15 pts (8 men), BMI 28.9±4, 80% on insulin– BMI ↓ 20%, all off DM meds d/c’d within 1 mo in 80%– At 3 mos, all euglycemic and off meds– FBS 233±87 to 89±12; HgbA1c 10.1±2.0% to 6.1±0.6%– ↓ ↓ cardiovascular risk factors for MI, stroke

Page 35: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 6, 2010(Con’t)

• Martin et al. Socioeconomic disparities in eligibility and access to bariatric surgery: a national population-based analysis. 8-15– NHANES data: 22+ million eligible for bariatric surgery– Eligible lower family incomes and educational levels, <

access to healthcare, 1/3 uninsured or underinsured– 75% bariatric surgery in Caucasians, 80% > income, 82%

private insurance

Page 36: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

BEST OF SOARD: Vol 6, 2010(Con’t• Josbeno et al. Physical activity and physical function changes in

obese individuals following RYGB. pp. 361-6– 20 pts, at 3 mos: X daily steps 4621±3701 to 7370±4240, 6 min walk

test: 393±62 to 446±41– Significant ↑ SF-36 physical function subscale

• Fernandez-Esparrach et al. Peroral endoscopic anastomotic reduction for the treatment of intractable dumping syndrome following RYGB. pp. 36-40– 6 pts, successful narrowing stoma, relief of dumping symptoms for

median f/u 636 days

Page 37: THE BEST OF SOARD Harvey Sugerman, MD, FACS, FASMBS Editor-in-Chief Surgery for Obesity and Related Diseases

OTHER MAJOR ARTICLES

• Christou et al: ↓Quebec mortality. Ann Surg

• Sjostrom et al: ↓ SOS mortality at 10 y. NEJM

• Adams et al: ↓ Utah mortality. NEJM

• Peters et al: ↓ Australian LAGB mortality

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OTHER MAJOR ARTICLES• O’Brien et al: Randomized LAGB BMI 30-35. Ann Intern Med

2006;144:625-33• Perioperative safety in the longitudinal assessment of bariatric

surgery. NEJM 2009;361:445-54• Smith et al: ↓ maternal transmission obesity. J Clin Endocr Metab

2009;94:4275-83• Keating et al: Cost efficacy, randomized LAGB for diabetes.

Diabetes Care 2009;32:580-4• O’Brien et al: LAGB in severely obese adolescents: a randomized

trial. JAMA 2010;303:519-26.

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