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9 th Annual Meeting DELIRIUM RECOGNITION AND REDUCTION: BENCH TO BEDSIDE CONSIDERATIONS JUNE 16-18, 2019 BOSTON PARK PLAZA 50 PARK PLAZA, BOSTON, MA 02116 #ADS19Boston

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9th Annual MeetingDELIRIUM RECOGNITION AND REDUCTION: BENCH TO BEDSIDE CONSIDERATIONSJUNE 16-18, 2019BOSTON PARK PLAZA 50 PARK PLAZA, BOSTON, MA 02116

#ADS19Boston

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Hotel AccommodationsA block of rooms has been reserved at the Boston Park Plaza, 50 Park Plaza at Arlington Street, Boston, Massachusetts 02116. Room rate is $269 single/double occupancy plus tax. These rates are limited, so reserve your room early by visiting: https://goo.gl/JZkA3N or by calling 617-379-7129. Please mention the American Delirium Society 2019 Annual Meeting when making your reservations. The deadline to book your hotel reservation is May 15, 2019 5:00pm EST. After this deadline, rooms will be provided on a space available basis only.

Following a landmark renovation, the Boston Park Plaza offers guests all the charisma and deeply individual charm of a historic hotel with the effortless comforts of a new one. The hotel offers incomparable proximity to everything that makes Boston a treasured destination. It is one of the most sought-after hotels near Boston Common an ideal location among the hotels in downtown Boston, just steps away from the Public Garden, Theater District and many of the city’s most popular historical sites.

WelcomeWelcome to Boston, Massachusetts, for the 2019 Annual Meeting of the American Delirium Society! The 3-day conference, which is expected to draw more than 400 investigators, educators, and clinicians from all spectrums of healthcare, is truly the destination for professionals dedicated to delirium care at every level of their career.

The ADS meeting is all about learning, networking and making connections and engages a diverse group of attendees across many disciplines and countries, – all dedicated to make a difference in patients across all care settings who are at risk for delirium or who develop delirium.

Our 2019 Annual Meeting is larger than ever with more than 25 symposia and workshops, 10 oral abstract sessions, a large poster session and a robust all-day pre-conference. There will be over 100 internationally-recognized invited faculty who will deliver cutting edge clinical and research presentations encompassing all aspects of delirium care. We are proud to say that at ADS 2019 there will be something for everyone!

Don’t miss the following important events:

• Adynamic,fullday,pre-conference: through interactive didactic sessions, delirium assessment simulation training and small group breakouts, this intense curriculum will provide you with the skills to make important practice changes at your institution.

• Plenaries from internationally recognized translational, clinical and policy experts.

• Workshops focused on practice improvement, education, delirium billing/coding, research design/ biostatistics, NIH funding and translational research.

• Symposia focused on imaging, biomarkers, big data, core measures, ICU practice change, sleep, prediction, palliative care, pediatrics and post-operative prevention.

• Engagement with our industrypartners.

• The NIDUSinvestigators will provide an update on their efforts to boost delirium research infrastructure and training.

• Presentations of more than 40oralabstracts moderated by senior investigators in the field.

• A postersession moderated by experts in the field.

• Breakfastsessions for new investigators and special interest groups.

• A Mondaynightdinnerboatcruise on Boston Harbor.

Finally, we wish to acknowledge the hard work and outstanding efforts of the Conference Planning Committee.

We welcome you to ADS 2019 and hope you take advantage of all Boston has to offer.

ADSBoston2019ConferencePlanningCommitteeClay Angel, MDAndrew Auerbach, MDLeanne Boehm, RN, PhDKristin Brooks, MDHeidi Engel, DPTTimothy Girard, MD, MPHDae Kim, MD, MPH, ScD

Heidi Lindroth, RN, PhDMark Oldham, MDPratik Pandharipande,

MD, MSCIStephanie Rogers, MSJane Saczynski, PhDHeidi Smith, MD, MSCI

JohnDevlin,PharmDCo-Chair Boston 2019President, American

Delirium Society

BabarKhan,MD,MSCo-Chair Boston 2019President-Elect,

American Delirium Society

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FacultyMeeraAgar,MBBS,PhDUniversity of Technology Sydney

Sydney, Australia

ClayAngel,MDKaiser PermanenteSan Rafael, CA

RakeshArora,MD,PhDUniversity of ManitobaWinnipeg, MB, Canada

AndrewAuerbach,MD,MPH

University of California - San Francisco

San Francisco, CA

C.AdrianAustin,MD,MSCR

University of North Carolina

Chapel Hill, NC

MichaelAvidan,MBBChBarnes Jewish HospitalWashington UniversitySt. Louis, MO

ShariBiswal,MSNUniversity of Alabama Birmingham

Birmingham, AB

DanaBisson,MSN,RNConcord HospitalConcord NH

LeanneBoehm,PhD,RNVanderbilt UniversityNashville, TN

KatrinaBooth,MDUniversity of Alabama Birmingham

Birmingham, AB

MalazBoustani,MD,MPHIndiana UniversityIndianapolis, IN

BeckyBriesacher,PhD,PharmD

Northeastern UniversityBoston, MA

KristenBrooks,MDKaiser PermanenteSan Rafael, CA

CharlesBrown,MDJohns Hopkins UniversityBaltimore, MD

EmeryBrown,MD,PhDMassachusetts Institute of Technology/

Massachusetts General Hospital

Boston, MA

ShannonBrownlee,MScLown Institute/Harvard University

Boston, MA

NathanBrummel,MD,MSc

Vanderbilt UniversityNashville TN

JanBusby-Whitehead,MD

University of North Carolina

Chapel Hill, NCShirleyBush,MBBSUniversity of OttawaOttawa, ON, Canada

NollCampbell,PharmD,MS

Purdue University/Regenstrief Institute

Indianapolis, IN

IndalecioCarboniBisso,MD

Hospital Italiano de Buenos Aires

Buenos Aires, Argentina

FedericoCarini,MDHospital Italiano de Buenos Aires

Beunos Airies, Argentina

MicheleCavallari,MD,PhD

Brigham and Women’s Hospital/

Harvard UniversityBoston, MA

RameelaChandrasekhar,PhD

Vanderbilt University Nashville TN

StacieDeiner,MD,MSMt Sinai HospitalNew York, NY

JohnDevlin,PharmDNortheastern UniversityBoston, MA

MarieDewitt,MDOscar G. Johnson Veterans Affair Medical Center

Iron Mountain, MI

JenniferDongarra,RN,BSN,MM

Concord HospitalConcord, NH

LinDrury,PhD,RNPace UniversityNew York, NY

HeidiEngel,DPTUniversity of California - San Francisco Medical Center

San Francisco, CA

RobertaEstevesVieiradeCastro,MD

University of Rio de Janeiro

Rio de Janeiro, Brazil

LisEvered,MBiostat,MSc,PhD

University of Melbourne Melbourne, Australia

JoshFessel,MD,PhDNational Heart, Lung, and Blood Institute

Bethesda, MD

DonnaFick,PhD,MSNPennsylvania State University

State College, PA

KirstenFiest,MD,PhDUniversity of CalgaryCalgary, AB, Canada

TamaraFong,MD,PhDBeth Israel Deaconess Medical Center

Harvard UniversityBoston, MA

D.CatherineFuchs,MD,DFAACAP

Vanderbilt UniversityNashville, TN

MaalobeekaGangopadhyay,MD

Columbia University, New York, NY

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Faculty continuedFlaviaGarcez,MDUniversidade de San Paulo,

San Paulo, Brazil

TimothyGirard,MD,MScUniversity of PittsburghPittsburgh, PA

DmitriyGolovyan,MDIndiana UniversityIndianapolis, IN

DeborahHa,SLP,MSUniversity of California Medical Center

San Francisco, CA

JinHan,MD,MScVanderbilt UniversityNashville, TN

BarbaraHeath,MSN,RNVA Northeast Ohio Healthcare System

Cleveland, OH

AnnemarieHosie,PhD,RN

University of Technology Sydney

Sydney, Australia

TammyHshieh,MD,MPH

Brigham and Women’s Hospital/

Harvard UniversityBoston, MA

ChristopherHughes,MDVanderbilt UniversityNashville, TN

SharonInouye,MD,MPHHebrew Senior Life/Harvard UniversityBoston, MA

RichardJones,ScDBrown UniversityProvidence, RI

BenjaminKalivas,MDMedical University of South Carolina

Charleston, SC

BirenKamdar,MD,MBA,MHS

University of California San Diego

San Diego, CA

BabarKhan,MD,MSIndiana UniversityIndianapolis, IN

SikandarKhan,DO,MSIndiana UniversityIndianapolis, IN

DaeKim,MD,MPH,ScD

Brigham and Women’s Hospital/

Harvard UniversityBoston, MA

EyalKimchi,MD,PhDMassachusetts General Hospital

Harvard UniversityBoston, MA

AliceKinsler,MA,ATRConcord HospitalConcord NH

KarlaKrewulak,PhDUniversity of CalgaryCalgary, AB, Canada

SapnaKudchadkar,MD,PhD

Johns Hopkins UniversityBaltimore, MD

PeterLawlor,MB,MMedSc

University of OttawaOttawa, ON, Canada

LynLindpaintner,BSN,MD

Concord HospitalConcord NH

HeidiLindroth,PhD,RNIndiana UniversityIndianapolis, IN

DebbieLong,B.Nurs,M.Nurs.,PhD

Children’s Health Queensland

Brisbane, Australia

TanyaMailhot,RN,PhDNortheastern UniversityBoston, MAMontreal Heart Institute Montreal, PQ, Canada

JoseMaldonado,MDStanford UniversityPalo Alto, CA

EdwardMarcantonio,MD,SM

Beth Israel Deaconess Medical Center/

Harvard UniversityBoston, MA

EmilyMarsh,RN,MSN,ONC

Concord HospitalConcord, NH

KerriMaya,MSLRNSutter Santa Rosa HospitalSanta Rosa, CA

PatriciaMesa,MDHospital Pasteur Montevideo, Uruguay

DaleNeedham,MD,PhDJohns Hopkins UniversityBaltimore, MD

LaraNelson,MDUniversity of Southern California

Los Angeles, CA

KarinNeufeld,MD,MPHJohns Hopkins UniversityBaltimore, MD

EstherOh,MD,PhDJohns Hopkins UniversityBaltimore, MD

MarkOldham,MDUniversity of RochesterRochester, NY

MeredithPadillaPhD,MSN,RN,CCRN-CMC/CSC

Hoag Memorial HospitalNewport Beach, CA

ValeriePage,MBBChWatford General HospitalWatford, United Kingdom

PratikPandharipande,MD,MSCI

Vanderbilt UniversityNashville TN

AaronPinkhasov,MDNYU-Winthrop HospitalMineola, NY

LeoPozuelo,MD,FACPThe Cleveland ClinicCleveland, OH

TracyRichmond,MSN,RN

VA Northeast Ohio Healthcare System

Cleveland, OH

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Faculty continuedLuciRoberts,PhDNational Institute of AgingBethesda, MD

StephanieRogers,MD,MSUniversity of California San Francisco

San Francisco, CA

LouiseRose,PhD,RNKing’s College London, United Kingdom and Sunnybrook Health Sciences Centre

Toronto, Canada

JamesRudolph,MDProvidence VA Medical Center/Brown University

Providence, RI

JaneSaczynski,PhDNortheastern UniversityBoston, MA

AnnaSatake,RN,GCNSKaiser Permanente Vacaville, CA

KendraSeavey,MPHCare.CoachNew York, NY

FrederickSieber,MDJohns Hopkins UniversityBaltimore, MD

EmilySimmons,MSNUniversity of Alabama Birmingham

Birmingham, AB

YoannaSkrobik,MD,MSc

McGill UniversityMontreal, PQ, Canada

ArjenSlooter,MD,PhDUniversity Medical Center Utrecht

Utrecht, Netherlands

HeidiSmith,MD,MScVanderbilt UniversityNashville, TN

LaurenceSolberg,MDUniversity of FloridaVA Geriatric Research Education and Clinical Center

Gainesville, FL

TaraSoudant,OTUniversity of California Medical Center

San Francisco, CA

JoannaStollings,PharmD

Vanderbilt University Medical Center

Nashville, TN

NiccoloTerrando,PhDDuke UniversityDurham, NC

ThomasTravison,PhDHebrew Senior Life/Harvard University

Boston, MA

MarkvandenBoogaard,PhD,RN

University Medical Center Radboud

Nijmegen, Netherlands

EduardVasilevskis,MD,MPH

Vanderbilt UniversityNashville TN

SarinnaphaVasunilashorn,PhD

Beth Israel Deaconess Medical Center/

Harvard UniversityBoston, MA

SophiaWang,MDIndiana UniversityIndianapolis, IN

VictorWang,MSCare.CoachNew York, NY

ChristineWaszynskiDNP,APRN

Hartford HospitalHartford, CT

MichelleWeckmann,MD,MS

University of IowaIowa City, IA

SharonWexler,PhD,RNPace UniversityNew York, NY

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• Evidence-based methods for recognizing delirium in patients in outpatient, hospital and long-term care settings

• Evidence-based strategies for preventing/reducing delirium in outpatient, hospital and long-term care settings

• Novel strategies to develop, implement and evaluate health system delirium reduction efforts

• New research focused on delirium epidemiology, diagnosis, prevention and treatment

MissionoftheADSThe goals of the American Delirium Society are to foster research, education, quality improvement, advocacy & implement science to minimize the impact of delirium on short- and long-term health and well-being of patients.

AccreditationStatementPhysicians / Nurses / PharmacistsIn support of improving patient care, this activity has been planned and implemented by Amedco, LLC and the American Delirium Society. Amedco, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

CreditDesignationStatement– Amedco, LLC designates this live activity for a maximum of 20.75 AMA PRA Category 1 CreditsTM for physicians and 20.75 contact hours for nurses and 20.75 knowledge-based contact hours for pharmacists. Learners should claim only the credit commensurate with the extent of their participation in the activity.

NOTEtoPharmacists:TheonlyofficialStatementofCreditistheoneyoupullfromCPEMonitor.Youmustrequestyourcertificatewithin30daysoftheactivitytomeetthedeadlineforsubmissiontoCPEMonitor.

Date:Monday, June 17, 2019

Nothing can beat the feeling of going out on the water aboard the Provincetown II, Boston Harbor’s largest cruise ship. Enjoy the views of Boston’s glorious skyline and the beautiful harbor islands from the ships immaculately maintained and expansive open decks. There will be a dinner buffet and cash bar.

Time:Boat departs at 7:30pm and returns at 9:30pm

Where: Attendees will need to transport themselves from the Boston Park Plaza to the Spirit of Boston, 200 Seaport Boulevard, Commonwealth Pier (1.8 miles from hotel). The pier is located next to the Seaport Hotel and World Trade Center.

Cost: $60 per person (see registration form)

Attire: Casual, Weather Appropriate

Learning Objectives

Program Information

Boston Harbor Dinner Cruise (Optional)

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Pre-Conference Program ScheduleSunday, June 16, 2019

Morning Session - Boston Park Plaza Hotel

Afternoon Session Northeastern University – Bouve College of Health Sciences

7:00 am – 7:30 am RegistrationandContinentalBreakfastBerkley/Clarendon Foyer

7:30 am – 7:35 am WelcomeandIntroduction Leanne Boehm, PhD, RN & Heidi Lindroth, PhD, RN Georgian

7:35 am – 7:55 am HistoryofDeliriuminClinicalPractice:AJourney Pratik Pandharipande, MD, MSCI Georgian

7:55 am – 8:30 am DeliriumEpidemiologyandPhenotypes Karin Neufeld, MD, MPH Georgian

8:30 am – 9:10 am DeliriumPathophysiology&RelationshiptoCognition Christopher Hughes, MD Georgian

9:10 am – 9:30 am CoffeeBreakandNetworkingBerkley/Clarendon Foyer

9:30 am – 10:15 am DeliriumMonitoringinChildrenandAdultsDebbie Long, B. Nurs, M. Nurs, PhD & Anna Satake, RN, GCNS Georgian

10:15 am – 10:45 am Non-PharmacologicStrategiestoPreventandManageDelirium Tammy Hshieh, MD, MPH Georgian

10:45 am – 11:15 am PharmacologicStrategiestoPreventandManageDelirium Noll Campbell, PharmD, MS Georgian

11:15 am – 11:45 am DeliriumOutcomes Timothy Girard, MD, MSc Georgian

11:45 am – 12:00 pm BusTransportationfromBostonParkPlazaHoteltoNortheasternUniversity

12:00 pm – 1:00 pm Lunch(provided) Behrakis Health Sciences Center Lobby (4th Floor)

1:00 pm – 1:15 pm OrientationtoSimulation&InnovationForumProcess(4th Floor)

1:15 pm – 2:30 pm (Concurent Sessions) Simulations–GoldsteinInterprofessionalSimulationCenter(GroupB)(011, 012, 014, Behrakis Building)*Simulation stations will include demonstrations/performance of CAM-ICU, ICDSC, psCAM-ICU, pCAM-ICU, CAPD, 4AT, 3D-CAM, RADAR, FAM-CAM along with a debrief/troubleshooting opportunities.

InnovationForum:AddressingChallengestoImplementation(GroupA)(310, 315, 3rd Floor)Malaz Boustani, MD, MPH *Simultaneous implementation challenge forums will be offered on a first-come, first-serve basis. Attendees will choose preferred forum at time of registration.

2:30 pm – 2:45 pm Break

2:45 pm – 4:00 pm (Concurent Sessions) Simulations–GoldsteinInterprofessionalSimulationCenter(GroupA)(011, 012, 014, Behrakis Building)

InnovationForum:AddressingChallengestoImplementation(GroupB) (310, 315, 3rd Floor)

4:00 pm – 4:55 pm LifeAfterDelirium:InterviewwithPatientandFamilyMember Leanne Boehm, PhD, RN

4:55 pm – 5:00 pm ClosingCommentsandAdjournment

5:00 pm – 5:15 pm BusTransportationfromNortheasternUniversitytoBostonParkPlazaHotel

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Gold Sponsors

Silver Sponsors

Partners

Thank you to our Sponsors and Partners!

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Program ScheduleMonday, June 17, 2019

Time Event Location

7:00–8:00am

BreakfastandRegistration Arlington/Berkeley/ Clarendon Foyer

Mentor-MenteeBreakfast Berkeley/Clarendon/Hancock

ClinicalPracticeAreaBreakfast Arlington

8:00–8:30am Welcome,PresidentialAddress,RecognitionofPartnerOrganizations,MeetingAnnouncements Georgian

8:30–9:15am

Plenary: Dale Needham, MD, PhD TheHeadBoneisConnectedtotheBodyBone:TheRoleofPhysicalRehabilitationonDeliriumintheICUandBeyondModerator: Babar Khan, MD, MS

Georgian

9:15–10:00amPlenary: Niccolo Terrando, PhDWhenInflammationMeetsNeurodegeneration:APerfectStormforPostoperativeDeliriumModerator: Esther Oh, MD, PhD

Georgian

10:00–10:30amCoffeeBreakandExhibits Arlington/Berkeley/

Clarendon Foyer

ExhibitorTheater:Philips Research: Towards Delirium Prevention and Detection Thomas Falck, MSc Terrace

10:30–11:30a

m

Symposium:InterdisciplinaryApproachtoPediatricDelirium:EvolutionofModelsofCarewithApplicationofPractice-BasedEvidencetoOptimizeBrainHealthModerator: Heidi Smith, MD, MSc10:30–10:45am DevelopmentalNuancesofDeliriumScreeninginChildren Maalobeeka Gangopadhyay, MD10:45–11:00am BeyondSedation:ImplicationsofRiskFactorsforDecisionMaking Heidi Smith, MD, MSCI 11:00–11:15am ExpandingOurSkillSets:InterdisciplinaryCollaborationinthePICU D. Catherine Fuchs, MD, DFAACAP11:15–11:30am Post-PICUBrainHealth:ANewModel Lara Nelson, MD

Georgian

Symposium:TheRoleofNovelBiomarkerstoEvaluateDeliriumOutcomesintheCriticallyIllModerator: Babar Khan, MD, MS10:30–10:45am PathwaystoDelirium:AnUnderstandingofDeliriumThroughProteomics andBiomarkers Sikandar Khan, DO, MS 10:45–11:00am MeasuresofInflammation,OxidativeStressandDeliriumDuringCriticalIllness Timothy Girard, MD, MSc 11:00–11:15am EndothelialandBrainInjuryMarkersandICUDelirium Christopher Hughes, MD 11:15–11:30am TheNIAResearchFrameworkforMCIandADRDandTheirRelevanceto BiomarkerResearchforDelirium Sophia Wang, MD

Arlington

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Program ScheduleMonday, June 17, 2019 continued

Time Event Location

10:30–11:30a

m OralAbstractSession:DeliriumintheNeurologicallyInjuredModerators: Tamara Fong, MD, PhD & Eyal Kimchi, MD, PhD10:30–10:45am ThePredisposingandPrecipitatingFactorsforDeliriuminanObservational Cohortof1,487NeurologicalPatients Carl Zipser, Balgrist University Hospital, Zurich, Switzerland10:45–11:00am DeconstructingPost-StrokeDeliriuminaProspectiveCohortofPatientswith IntracerebralHemorrhage Michael Reznik, Brown University, Providence, RI11:00–11:15am PrescribingPatternsRelativetoDeliriumRecognitioninStrokePatients Sophia Ryan, Massachusetts General Hospital/Harvard University, Boston, MA11:15–11:30am EffectsofNeurologicInjuryonDeliriumDurationandHospitalandICU LengthofStay Heidi Smith, Vanderbilt University Medical Center, Nashville, TN

Berkeley/Clarendon

11:30a

m–12:30pm

Roundtable:DeliriumRecognitionandReduction:PracticesAcrosstheAmericasModerator: Rakesh Arora, MD, PhDRoberta Esteves Vieira de Castro, MD, Patricia Mesa, MD, Flavia Garcez, MD, Indalecio Carboni Bisso, MD & Jose Maldonado, MD

Terrace

Year-in-Review:DeliriumPrediction,AssessmentandImplementationModerator: Noll Campbell, PharmD, MS11:30–11:50am PredictionModels Michelle Weckmann, MD, MS11:50am–12:10pm Assessment Jin Han, MD, MSc 12:10–12:30pm Implementation/Non-Pharm Joanna Stollings, PharmD

Georgian

NetworkforInvestigationofDelirium:UnifyingScientists(NIDUS):OverviewandUpdatesIntroduction:Sharon Inouye, MD, MPHPilotsandInnovationTaskForce:Michael Avidan, MBBChMentorshipandCareerDevelopmentTaskForce:Donna Fick, PhD, MSNDisseminationTaskForce:Jan Busby-Whitehead, MD & Andrew Auerbach, MD, MPHMeasurementandHarmonizationCore:Richard Jones, ScD & Dale Needham, MD, PhD ResearchResourcesCore:Edward Marcantonio, MD, SM, Pratik Pandharipande, MD, MSCI & Thomas Travison, PhD

Arlington

Workshop:ADeliriumTripleThreat:3Phenotypes,3Settings,and3DifferentRehabilitationProfessionalsModerator: Heidi Engel, DPT11:30–11:50am TheOccupationalTherapist Tara Soudant, OT 11:50am–12:10pm ThePhysiotherapist Heidi Engel, DPT12:10–12:30pm TheSpeechLanguagePathologist Deborah Ha, SLP, MS

Berkley/Clarendon

12:30–1:45pm Lunch Grand Ballroom A & B

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Program ScheduleMonday, June 17, 2019 continued

Time Event Location

1:45–

2:45pm

Symposium:TheABCDEFBundle:ImplementationandApplicationConsiderationsModerator: Dale Needham, MD, PhD 1:45–2:00pm ClinicianRoles&Teamwork Leanne Boehm, RN, PhD 2:00–2:15pm ConsiderationsinCountrieswithFewerResources Federico Carini, MD 2:15–2:30pm OptimizationofNon-MobilityRehabilitationStrategies Nathan Brummel, MD, MSc 2:30–2:45pm BoostingFamilyEngagement Kirsten Fiest, MD, PhD

Georgian

1:45–2:45p

m

Symposium:UtilizingNeuro-MonitoringandNeuro-ImagingModalitiestoPredictPostoperativeCognitiveOutcomesModerator: Frederick Sieber, MD1:45–2:00pm IntraoperativeSedationMonitoringandCognitiveOutcomes Frederick Sieber, MD2:00–2:15pm RelationshipBetweenCerebralAutoregulationMonitoringandPostoperative Outcomes Charles Brown, MD 2:15–2:30pm NovelNeuralSignalProcessingTechniquestoPredictPostoperative CognitiveOutcomes Emery Brown, MD, PhD2:30–2:45pm DiffusionMRIPre-OperativelytoPredictPostoperativeOutcomes-Ready forRealTime? Michele Cavallari, MD, PhD

Arlington

NIDUSOralAbstractSession#1Moderators: Donna Fick, PhD, MSN & Michael Avidan, MBBCh1:45–2:00pm AssociationBetweenComponentsoftheDeliriumSyndromeandMortality: ASystematicReviewandIndividualPatientDataAnalysis Zoe Tieges, University of Edinburgh, Edinburgh, Scotland 2:00–2:15pm ATelehealthDeliriumCoachingInterventionforFamilyCaregiversof Community-DwellingOlderAdultswithDementia Deborah D’Avolio, Florida Atlantic University, Boca Raton, FL2:15–2:30pm TheAssociationBetweenDeliriumSeverityandLong-TermClinical OutcomesAmongPersonswithandwithoutAlzheimer’sDiseaseand RelatedDementias Tammy Hshieh, Brigham and Women’s Hospital/Harvard University, Boston, MA2:30–2:45pm AnInflammatorySignatureofPostoperativeDelirium:Importanceof NeuroinflammationandSystemicInflammation Sarinnapha Vasunilashorn, Beth Israel Deaconess Medical Center/Harvard University, Boston, MA

Berkeley/Clarendon

Workshop:InnovativeGeriatricProgramstoFacilitateHealthSystemDeliriumReductionProgramsModerator: Christine Waszynski, DNP, APRN1:45–2:05pm GeriatricScholarsProgram Emily Simmons, MSN 2:05–2:25pm ACETrackerProgram Katrina Booth, MD & Shari Biswal, MSN2:25–2:45pm AgeFriendlyHealthSystemsProject Christine Waszynski DNP, APRN

Terrace

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Time Event Location

2:45–3:45p

m

Symposium:WhatCanWeLearnAboutRecentAntipsychoticDeliriumResearch?Moderator: Karin Neufeld, MD, MPH2:45–3:00pm TheMIND-USARCT Timothy Girard, MD, MSc 3:00–3:15pm TheREDUCERCT Mark van den Boogaard, PhD, RN 3:15–3:30pm HowIUseAntipsychoticsintheICU Valerie Page, MBBCh3:30–3:45pm UtilizationandSafetyofAntipsychoticsinHospitalizedOlderAdults Dae Kim, MD, MPH, ScD

Georgian

Workshop:SustainingOrganization-WideDeliriumRecognition&InterventionPrograms:ATaleofFourCentersModerator: Leo Pozuelo, MD, FACP2:45–2:56pm TheClevelandClinicExperience Leo Pozuelo, MD, FACP 2:56–3:07pm TheMedicalUniversityofSouthCarolinaExperience Benjamin Kalivas, MD 3:07–3:18pm UsingContinuousProcessImprovementtoSustainaDeliriumProgramatUCSF Stephanie Rogers, MD, MS 3:18–3:30pm TheKaiserPermanenteExperience Kristen B. Brooks, MD3:30–3:45pm AudienceSharingandQuestions

Arlington

NIDUSOralAbstractSession#2Moderators: Andrew Auerbach, MD, MPH & Jan Busby-Whitehead, MD2:45–3:00pm AssociationBetweenCumulativeHaloperidolDoseand28-and90-day MortalityinCriticallyIllAdults:Post-HocAnalysisoftheREDUCEStudy Matthew Duprey, Northeastern University, Boston, MA 3:00–3:15pm DeliriumTransitionClinic:AnInnovativeModelofCaretoMitigateaCascadeof ProblemsAfterDelirium Ariba Khan, Aurora Medical Group/University of Wisconsin, Milwaukee, WI3:15–3:30pm DeliriumSeverityandClinicalOutcomesareBothPredictedbyMachine LearningAnalysisofRoutineEEG Eyal Kimchi, Massachusetts General Hospital/Harvard University, Boston, MA3:30–3:45pm SOMAscanasaDiscoveryPlatformtoIdentifyPlasmaProteinBiomarkers forPostoperativeDelirium Towia Liberman, Beth-Israel Deaconess Medical Center/Harvard University, Boston, MA

Berkeley/Clarendon

3:45–4:15pm CoffeeBreakandExhibits Arlington/Berkeley/Clarendon Foyer

Program ScheduleMonday, June 17, 2019 continued

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Time Event Location

4:15–5:15p

m

Symposium:AddressingtheClinicalChallengesofDeliriumManagementinPalliativeCareSettingsModerator: Shirley Bush, MBBS 4:15–4:30pm InformationalSupporttoPatientsandFamilies Shirley Bush, MBBS 4:30–4:45pm DeliriumScreening Peter Lawlor, MB, MMedSc 4:45–5:00pm PharmacologicManagement Meera Agar, MBBS, PhD5:00–5:15pm Non-PharmacologicalInterventions Annemarie Hosie, PhD, RN

Georgian

Symposium:NovelBiomarkersforPredictingPostoperativeDeliriumIncidenceandProgressionofCognitiveDeclineModerator: Lis Evered, MBiostat, MSc, PhD 4:15–4:35pm NovelBiomarkerstoPredictDeliriumandOtherPerioperative NeurocognitiveDisordersFollowingAnaesthesiaandSurgery Lis Evered, MBiostat, MSc, PhD4:35–4:55pm BiomarkersofPostoperativeDeliriuminHipFracture Esther Oh, MD, PhD 4:55–5:15pm Gene-proteinInteractionsofApolipoproteinEandCatechol-O- MethyltransferaseGenotypeswithC-ReactiveProteinonPostoperativeDelirium Sarinnapha Vasunilashorn, PhD

Arlington

OralAbstractSession:IntensiveCareUnit-#1Moderators: Timothy Girard, MD, MSc & Yoanna Skrobik, MD, MSc4:15–4:30pm Non-EEGSleepStagingforDeliriumintheICU:ADeepLearningApproach Wolfgang Ganglberger, Massachusetts General Hospital, Boston, MA4:30–4:45pm ICUDeliriumEducationMaterialsforFamilyCaregiversofCriticallyIllPatients Karla Krewulak, University of Calgary, Calgary, AB, Canada4:45–5:00pm ProphylacticHaloperidolEffectsonLong-TermQualityofLifeinCriticallyIll PatientsatHighRiskforDelirium:ResultsoftheREDUCEStudy Paul Rood, University Medical Center, Radboud, Nijmegen, NL5:00–5:15pm SustainedAttentionTestinginDeliriousandNon-DeliriousCriticallyIllAdults Carol Chan, Johns Hopkins University, Baltimore, MD

Berkeley/Clarendon

Workshop:Deliriumvs.Encephalopathy:OptimizingDefinitions,DocumentationandBillingModerator: Clay Angel, MD 4:15–4:35pm DeliriumandEncephalopathy:WhatDefinitionsShouldWeUse? Arjen Slooter, MD, PhD 4:35–5:15pm OptimizingDeliriumandEncephalopathyDocumentationandBilling Clay Angel, MD & Kristen Brooks, MD

Terrace

5:15–6:45pm PosterViewingandReception(DiscussionGroupsonpages19-22) Grand Ballroom A & B

7:30–9:30pm BostonHarborDinnerCruiseProvincetown II, 200 Seaport Boulevard, Commonwealth Pier

Program ScheduleMonday, June 17, 2019 continued

14

Program ScheduleTuesday, June 18, 2019

Time Event Location

7:00–8:00am

BreakfastandRegistration Arlington/Berkeley/ Clarendon Foyer

ADSEducationCommitteeMeeting Arlington

ADSMembership/CommunicationCommitteeMeeting Berkeley

ADSResearchCommitteeMeeting Clarendon

8:00–8:30am AnnouncementsandAbstractAwards Georgian

8:30–9:15amPlenary: Edward Marcantonio, MD, SM BringingDeliriumIdentificationtotheBedsideModerator: Sarinnapha Vasunilashorn, PhD

Georgian

9:15–10:00amPlenary: Shannon Brownlee, MSc GettingtoGoldilocksCare:CanWeQuitDeliveringTooMuchCareandGettoJustRight?Moderator: John Devlin, PharmD

Georgian

10:00–10:30am CoffeeBreakandExhibits Arlington/Berkeley/Clarendon Foyer

10:30–11:30a

m

Symposium:CoreMeasuresforDeliriumResearchModerator: Louise Rose, PhD, RN10:30–10:45am ReportingofOutcomesandMeasuresinICUDeliriumStudies: Del-COrS Louise Rose, PhD, RN10:45–11:00am CoreOutcomeSetDevelopment:TheExperiencewithARDS SurvivorshipResearch Dale Needham, MD, PhD 11:00–11:15am ConsiderationsRegardingDelirium-RelatedCoreOutcomesin PalliativeCare Meera Agar, MBBS, PhD11:15–11:30am ApplicationofCoreOutcomesinDeliriumResearch Noll Campbell, PharmD, MS

Arlington

Symposium:Long-TermCognitiveDeclineAfterSurgery:TheInteractionBetweenFrailty,SurgeryandDeliriumModerator: Pratik Pandharipande, MD, MSCI10:30–10:50am Long-TermCognitiveConsequencesFollowingSurgery Lis Evered, MBiostat, MSc, PhD10:50–11:10am InfluenceofFrailtyonPostoperativeDeliriumandLong-term CognitiveOutcomes Rakesh Arora, MD , PhD11:10–11:30am EffectofSurgeryandAnesthesiaontheBrain Stacie Deiner, MD, MS

Georgian

15

Program ScheduleTuesday, June 18, 2019 continued

Time Event Location

10:30–11:30a

m

OralAbstractSession:Mechanisms/PathophysiologyModerators: Niccolo Terrando, PhD & Sarinnapha Vasunilashorn, PhD 10:30–10:45am AHumanandMouseModelStudyofInflammatoryChemokinesattheBlood CerebrospinalFluidBarrierandTheirRoleinDelirium Colm Cunningham, Trinity College, Dublin, Ireland10:45–11:00am EnergyMetabolismisaDriverofCognitiveDysfunctioninanAnimalModel ofDeliriumDuringDementia Colm Cunningham, Trinity College, Dublin, Ireland11:00–11:15am SerumNeurofilamentLightChainIsPersistentlyElevatedFollowingDelirium inOlderAdultsUndergoingElectiveSurgery Tamara Fong, Beth Israel Deaconess Medical Center/Harvard University, Boston, MA11:15–11:30am CholinergicTrajectoriesinPatientswithPostoperativeDelirium Anika Mueller, Charite Hospital, Berlin, Germany

Berkeley/Clarendon

Symposium:NavigatingCurrentlyExistingDeliriumEducationResources:ADSEducationCommitteePerspectivesModerator: Aaron Pinkhasov, MD 10:30–10:40am TheADSWebsite:YourSourceforDeliriumEducationalResources Aaron Pinkhasov, MD 10:40–10:50am ScreeningandAppraisaloftheEducationalResourcesforInclusion intheADSWebsite Tanya Mailhot, RN, PhD & Karla Krewulak, PhD10:50–11:00am UsingBedsideNursestoVetDeliriumEducationResources Kerri Maya, MSL, RN11:00–11:10am DeliriumEducationalResourcesforPatients,Family,andthePublic:TheBasics andBeyond Meredith Padilla PhD, MSN, RN, CCRN-CMC/CSC11:10–11:30am InteractiveDeliriumEducationProgramfortheInterdisciplinaryTeam Aaron Pinkhasov, MD

Terrace

11:30a

m–12:30pm

Symposium:The2018SCCMPain,Agitation,Delirium,ImmobilityandSleepPracticeGuidelines:ExploringtheEvidenceGapsModerator: John Devlin, PharmD11:30–11:45am Pain Yoanna Skrobik, MD, MSc11:45am–12:00pm Sedation Pratik Pandharipande, MD, MSc12:00–12:15pm Delirium Arjen Slooter, MD, PhD12:15–12:30pm Immobility Dale Needham, MD, PhD

Georgian

Workshop:StatisticalMethodsforDeliriumResearchModerator: Rameela Chandrasekhar, PhD11:30–11:50am ReproducibleResearch:WhatIsItandHowDoYouDoIt Thomas Travison, PhD 11:50am–12:10pm PragmaticRandomizedTrialsandHowTheyMaybeUsedinDelirium Research Rameela Chandrasekhar, PhD12:10–12:30pm PossibleBiasesandAppropriateStatisticalApproachesfor EvaluatingtheAssociationBetweenDeliriumandCognitiveFunction Richard Jones, PhD

Arlington

16

Program ScheduleTuesday, June 18, 2019 continued

Time Event Location

11:30a

m–12:30pm

OralAbstractSession:PostoperativeDelirium#1Moderators: Lis Evered, MBiostat, MSc, PhD & Sarinnapha Vasunilashorn, PhD11:30–11:45am DeliriumDetectionMethodologies:ImplicationsforOutcomeMeasurement inClinicalTrialsinPostoperativeDelirium Karin Neufeld, Johns Hopkins University, Baltimore, MD11:45am–12:00pm AssociationBetweenDeliriumandPatientReported-Outcomes30-Days FollowingMajorSurgery Angela Mickle, Washington University, St Louis, MO12:00–12:15pm BaselineDepressioninRelationtoPostoperativeDeliriuminHipFracture Patients Carol Chan, Johns Hopkins University, Baltimore, MD12:15–12:30pm TheEffectofPreoperativeDepressiveSymptomsonPostoperativeCognitive Dysfunction(POCD) Friedrich Borchers, Charite Hospital, Berlin, Germany

Berkeley/Clarendon

DevelopmentandImplementationofOrganization-WideDeliriumRecognition&InterventionPrograms:ConcordHospital(Concord,NH)andVANortheastOhioHealthcareSystem(Cleveland,OH)ExperiencesModerator: Lyn S. Lindpaintner, BSN, MDPresenters discuss successful approaches to central themes in delirium care and display useful materials.Station#1:Education: Jennifer Dongarra, RN, BSN, MM & Barbara Heath, MSN, RNStation#2:Interventions/Tools: Dana E. Bisson, MSN, RN & Alice Kinsler, MA, ATR Station#3:Informatics: Emily Marsh, RN, MSN, ONCStation#4:Overcomingresistance: Lyn S. Lindpaintner, BSN, MD & Tracy Richmond, MSN, RN

Terrace

12:30–2:00pm LunchOnYourOwn

2:00–3:00p

m

Symposium:DeliriumPredictionModerator: Timothy Girard, MD, MSc 2:00–2:20pm StaticDeliriumPredictionModels Mark van den Boogaard, PhD, RN 2:20–2:40pm DynamicDeliriumPredictionModels Eduard Vasilevskis, MD, MPH2:40–3:00pm MetholodologicalConsiderationsandAdaptiontoClinicalPractice Heidi Lindroth, RN, PhD

Georgian

Workshop:NIHFundingofInnovativeDeliriumResearchModerator: Jane Saczynski, PhD2:00–2:20pm NationalInstituteonAging Luci Roberts, PhD 2:20–2:40pm NationalHeartLungandBloodInstitute Josh Fessel, MD, PhD 2:40–3:00pm OpenDiscussion

Arlington

17

Program ScheduleTuesday, June 18, 2019 continued

Time Event Location

2:00–3:00p

m

OralAbstractSession:PostoperativeDelirium#2/AssessmentModerators: Pratik Pandharipande, MD, MSCI & Rakesh Arora, MD, PhD2:00–2:15pm PreoperativeFrailtyIncreasestheRiskforPostoperativeDeliriuminMajor Non-CardiacSurgicalPatients Elizabeth Mahanna-Gabrielli, University of Miami, Coral Gables, FL2:15–2:30pm DepthofSedationasanInterventionalTargettoReducePostoperative Delirium:MortalityandFunctionalOutcomesoftheSTRIDERandomized ClinicalTrial Frederick Sieber, Johns Hopkins University, Baltimore, MD2:30–2:45pm MarginalBenefitofCognitiveScreeningtoIdentifyPatientsatRiskfor PostoperativeDelirium Rachel Grasfield, Brigham and Women’s Hospital/Harvard University, Boston, MA2:45–3:00pm DiagnosticAccuracyoftheDelappSmartphoneTestforAssessing InattentioninDeliriuminGeriatricandIntensiveCareSettings Zoe Tieges, University of Edinburgh, Edinburgh, Scotland

Berkeley/Clarendon

IdentifyingandOvercomingBarrierstoImplementationofaNationalDeliriumCurriculumModerator: Laurence Solberg, MD2:00–2:15pm CurrentStateofDeliriumEducationintheUSA Laurence Solberg, MD2:15–2:30pm UsingtheVAExperiencetoInformaNationalDeliriumEducation Marie Dewitt, MD2:30–2:45pm HealthSystemDeliriumEducationPrograms:OpportunitiesandBarriers James Rudolph, MD2:45–3:00pm TheVADeliriumTeam:AModelforaNationalDeliriumCurriculum Laurence Solberg, MD

Terrace

3:00–4:00p

m

Symposium:TheSleep-DeliriumRelationshipintheHospitalized:OpportunitiestoImproveCareModerator: Mark Oldham, MD3:00–3:15pm SleepDisruptionasaRiskFactorforDelirium Mark Oldham, MD 3:15–3:30pm SleepAssessmentinRelationtoDelirium Biren Kamdar, MD, MBA, MHS 3:30–3:45pm SleepandDeliriuminCriticallyIllChildren Sapna Kudchadkar, MD, PhD 3:45–4:00pm TheLinkBetweenDeliriumandSleep–HowTightIsIt? Yoanna Skrobik, MD, MSc

Georgian

Workshop:UsingBigDatatoUnderstandandImproveDelirium-RelatedOutcomesModerator: Babar Khan, MD, MS3:00–3:30pm UsingHealthSystemData:StrokeandDelirium Babar Khan, MD, MS3:30–4:00pm UsingMedicareDatatoStudyDeliriuminLong-TermCareSettings Becky Briesacher, PhD, PharmD

Arlington

18

Program ScheduleTuesday, June 18, 2019 continued

Time Event Location

3:00

–4:00p

m

OralAbstractSession:DeliriumAssessmentModerators: Jane Saczynski, PhD & Richard Jones, PhD3:00–3:15pm ASingleQuestionontheAcuityofMentalStatusChangeImprovestheNu- DESC’sAbilitytoDiscriminateDelirium Mark Terrelonge, University of California San Francisco, San Francisco, CA 3:15–3:30pm EvaluationofScreeningInstrumentsfortheDetectionofPediatricDelirium duringCriticalIllness Debbie Long, Children’s Health Queensland, Brisbane, Australia3:30–3:45pm ValidationoftheQuickStanfordProxyTestforDelirium(qS-PTD),aHighly EffectiveandStraightforwardScreeningToolforDelirium Jose Maldonado, Stanford University, Palo Alto, CA3:45–4:00pm UseoftheBriefConfusionAssessmentMethodinaVeteranPalliativeCare Population:APilotValidationStudy Jo Wilson, Vanderbilt University Medical Center, Nashville, TN

Berkeley/Clarendon

4:00–5:00p

m

Symposium:NovelNon-PharmacologicStrategiestoReduceDeliriuminHospitalizedPatientsModerator: Mark van den Boogaard, PhD, RN4:00–4:15pm VirtualReality:ANewViewpointtoICUDeliriumTreatment Dmitriy Golovyan, MD 4:15–4:30pm ApplyingMusic:ANeurobiologicApproach Sikandar Khan, DO, MS4:30–4:45pm DevelopmentofDigitalAvators Victor Wang, MS & Kendra Seavey, MPH4:45–5:00pm ImplementationandEvaluationofDigitalAvators Sharon Wexler, PhD, RN & Lin Drury, PhD, RN

Georgian

Year-in-Review:DeliriumNeurobiologyandOutcomesModerator: Mark Oldham, MD4:00–4:20pm Biomarkers Sarinnapha Vasunilashorn, PhD 4:20–4:40pm Outcomes C. Adrian Austin, MD, MSCR4:40–5:00pm AnimalModels Eyal Kimchi, MD, PhD

Arlington

OralAbstractSession:IntensiveCareUnit-#2Moderators: Kirsten Fiest, MD, PhD & Biren Kamdar, MD, MBA, MHS4:00–4:15pm IntensiveCareUnit(ICU)DeliriumSeverityAssociatedwithIncreased Mortality Patricia Serrano, Indiana University, Indianapolis, IN4:15–4:30pm MotoricSubtypeofDeliriumandDisabilityafterCriticalIllness Kimberly Rengell, Vanderbilt University Medical Center, Nashville, TN4:30–4:45pm IncidenceandImpactofDeliriuminCritically-illPatientswithCancer Carina Marasigan-Stone, Memorial Sloan Kettering Cancer Center, New York, NY4:45–5:00pm PotentiallyInappropriateMedicationsIncreaseDeliriumMoreinHIV+than UninfectedPatients Kathleen Akgun, Yale University, New Haven, CT

Berkeley/Clarendon

19

Poster Viewing and ReceptionMonday June 17, 2019 • 5:15-6:45pm • LOFT/STUDIO 2

Poster Moderator Discussion Groups (5:45-6:15pm)

Poster # Poster Title Corresponding Author

GROUP A: Quality Improvement-1 – L. Pozuelo, MD

1Structured Delirium Care Pathway is Associated with Reductions in Length of Stay, Cost and Readmissions in Hospitalized Adults - on Behalf of the Delirium Reduction Campaign Writing Group

Sara LaHue

8 Evaluation of a Pharmacist-Driven Intervention to Reduce Deliriogenic Medication Use in a Health-System Wide Delirium Reduction Pathway Kelly Quinn

14 A Pilot Study Assessing the Feasibility of a Remote Telemedicine Delirium Assessment Tool Charles Austin

35 Use of Implementation Science Framework for the Implementation Process and Adherence Assessment of a Non-Pharmacological Delirium Prevention Program. Eduardo Tobar

47 Feasibility of Implementation of a Cognitive Vital Sign on an Acute Care of the Elderly Unit Timothy Wong

GROUP B: Quality Improvement-2 – L. Lindpaintner, RN, MD

58 Cognition Clinical Lead: A Role for Allied Health Brianna Walpole

61 Delirium Prevention Toolbox Supplies: The Journey to Sustainability Shari Biswal

64 Development and Outcomes of a Nurses-Driven Initiative for Prevention and Treatment of Delirium in Hospitalized Elderly Stasa Tadic

71 Improving Caregiver Education About Delirium Alex Tinianow

80 Delirium Incidence at a Large Academic Hospital Patrick Robbins

GROUP C: Surgery-1 – L. Evered, PhD

7 A Delirium Training for the Surgical Resident Mariah Robertson

12 Older Women Who Exercise Daily before Surgery Suffer from Less Postoperative Delirium Susie Lee

17 Delirium Triage Screen-Brief Confusion Assessment Method in Adult Acute Care: A Validation Study Jane Sederstrom

21 Postoperative Delirium Diagnosis in Older Adults Using the CAM-ICU Outside the ICU Titima Wongviriyawong

25 Machine Learning to Predict Postoperative Delirium Richard Jones

26 The Relationship Between Postoperative Delirium and Unplanned Perioperative Hypothermia in Non-Cardiac Adult Patients Doreen Wagner

GROUP D: Surgery-2 – F. Sieber, MD

16Intravenous Acetaminophen vs. Placebo Combined with Dexmedetomidine vs. Propofol on Postoperative Delirium in Older Cardiac Surgical Patients (DEXACET trial): A Randomized, Factorial, Clinical Trial

Balachundhar Subramaniam

28 Prevention of Early Postoperative Decline (PEaPoD): A Randomized Controlled Trial Investigating the Feasibility of a Perioperative Cognitive Training Program Brian O'Gara

30 C-Reactive Protein for Risk Prediction of Postoperative Delirium and Postoperative Cognitive Dysfunction Cornelia Knaak

60 The SANDMAN Study: Sleep Apnea, Neuroinflammation, and Cognitive Dysfunction Manifesting After Non-Cardiac Surgery Michael Devinney

77 Impact of Delirium Education on a Post-Surgical Unit Tru Byrnes

20

Poster # Poster Title Corresponding Author

GROUP E: Assessment-1 – K. Neufeld, MD, MPH

3 Creating a Cross-Walk Between Two Commonly Used Proxy-Based Measures of Cognitive Impairment to Assess Baseline Function in Patients with Delirium Shannon Malloy

5 Validation of the "4AT" Delirium Screening Tool in a Cardiac Surgery Patient Population Yui Chang

11 Utility of the 4AT Assessment of Delirium in Acute Care: A Multi-Center Blinded Independent Rater Diagnostic Test Accuracy Study Zoë Tieges

15 Comparative Effectiveness and Efficiency of 4 Delirium Screening Protocols Donna Fick

27 Creating a Cognitive Vital Sign for Detecting and Monitoring Delirium Haley Troy

18Validation and Transcultural Adaptation of the 3-Minute Diagnostic Interview for CAM (3D-CAM) for Delirium Detection in a Brazilian Cohort of Hospitalized Older Adults: Preliminary Results

Flavia Garcez

GROUP F: Assessment-2 – M. Oldham, MD

29 Comparison of Patient Reported Pain Between Delirious and Non-Delirious Patients Daniel Park

31 Validation and Transcultural Adaptation of the Confusion Assessment Method – Severity Score (CAM-S) in a Brazilian Cohort of Hospitalized Older Adults: Preliminary Results Flavia Garcez

32 Validation of the Portuguese Version of the 4 A’s Test (4AT) for Delirium Screening in Hospitalized Older Adults: Preliminary Results Flavia Garcez

40 Defining Best Practice Methods for Studies of Biological and Clinical Correlates of Delirium: An International Modified Delphi Study (Protocol) Ingrid Amgarth-Duff

41 Detecting Delirium: A Systematic Review of Identification Instruments Benjamin Helfand

GROUP G: Assessment-3 – S. Wang, MD

46 Simple Delirium Screening Tools for Delirium Detection in Older Hospitalized Medical Patients Apinantana Apiwathanant

88 Diagnostic Accuracy of the 4AT for Delirium Detection: A Systematic Review and Meta-Analysis Zoe Tieges

74 Enhancing the Detection of Delirium by Nurses in Acute Care Heidi Lindroth

75 Enhancing Delirium Detection Through Improved APRN-RN Communication Heidi Lindroth

84 The Stanford Proxy Test for Delirium (S-PTD), An Innovative Delirium Screening Tool: A Large Multicenter Validation Study Jose Maldonado

81 A Classification Conundrum: Delirious Mania Angela Wang

GROUP H: Critical Care-1 – A. Slooter, MD, PhD

6 Knowledge and Adherence to the ABCDEF Bundle: An Argentinian Survey Indalecio Carboni Bisso

4 Catatonia, Delirium and Coma: Implications for Mortality Jo Wilson

23 Decreasing Delirium Through Music: A Feasibility Trial Sikandar Khan

24 Tracking RASS and CAM-ICU from EEG Using Deep Learning in the ICU Haoqi Sun

34 Delirium Education Program for Intensive Care (ICU) Nurses: A Mixed Methods Research Study Meredith Padilla

Monday June 17, 2019 • 5:15-6:45pm • LOFT/STUDIO 2

Poster Moderator Discussion Groups (5:45-6:15pm)

21

Poster # Poster Title Corresponding Author

GROUP I: Critical Care-2: – D. Needham, MD, PhD

36 Improving Delirium Detection in the Medical ICU: An Interdisciplinary Approach to Delirium Screening Daniel Cucco

37 Association Between Sleep Quality and Delirium Occurrence in Critically Ill Adults: A Secondary Analysis of a Randomized Controlled Trial Matthew Duprey

42 Impact of Intensive Care Unit (ICU) Diary on Delirium Occurrence in the ICU and Prevalence of Distressing and Delusional Memories One Week Following Discharge Rakesh Arora

50 Instituting an Evidence-Based, Nurse-Driven ICU Mobility Protocol for an Adult Medical Intensive Care Unit Yun Kim

GROUP J: Critical Care-3: – M. van den Boogaard, PhD, RN

54 Adherence and Implementation to the ABCDEF Bundle in a Tertiary Care Hospital in Buenos Aires (Argentina) Ivan Huespe

63 Delirium in the ICU and Medium-Term Cognitive Outcome: A Prospective-Feasibility Cohort Study Federico Carini

65 Investigation of Sleep in the Intensive Care Unit Ryan Tesh

68 The Impact of Delirium and Impaired Consciousness on Withdrawal of Life-Sustaining Treatment After Spontaneous Intracerebral Hemorrhage Michael Reznik

69 The Predisposing and Precipitating Risk Factors for Delirium in Neurosurgery: An Observational Cohort Study of 949 Patients Carl Moritz Zipser

86 Investigating the Relationships Among Pain, Opioids and Next-Day Delirium Status in Older Adults in the Surgical Intensive Care Unit Kara Pavone

91 Antipsychotic Medication Prescribing Patterns for Management of Intensive Care Unit (ICU) Delirium in 8,872 Patients Christina Boncyk

GROUP K: Pediatrics/Neonates – H. Smith, MD, MSCI

20 Delirium Prevalence and Screening Compliance in Children Admitted to the ICU With Cardiac Disease Sean Barnes

87 Translation and Cultural Adaptation Process to Spanish of the Preschool Confusion Assessment Method for the Intensive Care Unit (psCAM-ICU) Milagros Figueroa

67 Ranitidine-Induced Delirium in a 7-Year-Old Girl: A Case Report Roberta Castro

73 Infant Delirium: Validation of a Bedside Tool and Meeting Challenges in Diagnosis Stacey Williams

GROUP L: Emergency Department – J. Han, MD, MSc

19 Evaluation of a Pharmacist-Directed Medication Review Program for Older Adults with Delirium in the Emergency Department: The SCREENED-ED Study Jodie Zheng

22 External Validation of Emergency Department Derived Delirium Prediction Models Using a Hospital-Wide Cohort Sangil Lee

52 Variability in Delirium Rates in Older ED Patients Enrolled in a National Multicenter Trial Jose Estrada-Codecido

Monday June 17, 2019 • 5:15-6:45pm • LOFT/STUDIO 2

Poster Moderator Discussion Groups (5:45-6:15pm)

22

Poster # Poster Title Corresponding Author

GROUP M: Mechanisms and Pathophysiology-1 – C. Hughes, MD, MSc

2Evidence That the Heightened Vulnerability of the Pre-Adolescent Population to Delirium Triggered by Anesthesia is Linked to Increased Blood-Brain Barrier Permeability Associated with Neovascularization and Rapid Brain Growth

George Godsey

10 Microbiome Dysbiosis and Postoperative Delirium Pathogenesis Yiying Zhang

44Using Machine Learning Algorithms to Identify Neurological Status of Critically Ill Adult Patients–Cerebral Oxygenation and Narcotic Dosing During the First 24-Hours Substantially Contribute to Neurological Status

Michael Wood

43 Epigenetic Mechanism of Delirium Pathophysiology: Hypothesis and Evidence from Preliminary Data

Gen Shinozaki

48 Are Biomarkers of Neuronal Damage Associated with Delirium Severity and Subsyndromal Delirium in Mechanically Ventilated Intensive Care Unit Patients with Sepsis?

Brianna Rosgen

GROUP N: Mechanisms and Pathophysiology-2 – E. Oh, MD, PhD

53 A Multi-Centre Feasibility Study Investigating the Impact of Cerebral Oxygenation on Delirium Development in the Early Stages of Critical Illness

Jasmine Khan

89 Detection of Early-Stage Alzheimer’s Pathology Using Blood-Based Autoantibody Biomarkers in Elderly Hip Fracture Repair Patients

Cassandra DeMarshall

57 Sub-Clinical Brain Failure: Identification of High Risk Mortality Patients and Prediction of Patient Outcomes Associated with Delirium with a Novel Bispectral Eeg Device

Gen Shinozaki

79 Neuroimaging in Delirium Shixie Jiang

GROUP O: Palliative Care/Older Adults – S. Inouye, MD, MPH

9A Qualitative Study of Patient, Family, Staff and Volunteer Perspectives During a Phase 2 Trial of a Multicomponent Non-Pharmacological Delirium Prevention Intervention for Inpatients with Advanced Cancer

Annmarie Hosie

45 Clinical Management of Delirium: The Response Depends on the Subtypes: An Observational Cohort Study in 602 Patients

Carl Moritz Zipser

51 Delirium Simulation on an Acute Care for Elders Unit Katrina Booth

59 Validation and Transcultural Adaptation of the Delirium Motor Subtyping Scale 4 (DMSS-4) in a Brazilian Cohort of Hospitalized Older Adults: Preliminary Results

Flavia Garcez

66 HELP: A Quality Improvement Project of a Delirium Prevention Program Marianne Klumph

GROUP P: Older Adults/Acutely Ill – N. Campbell, PharmD

62 Asenapine Causing Anticholinergic Delirium: A Case Report and Literature Review Kathleen Sheehan

72Effectiveness of Occupational Therapy (OT) Services as a Non-Pharmacologic, Multicomponent Intervention in the Prevention and Treatment of Delirium in Hospitalized Patients

Emma Monaghan

76 National Trends in Delirium Prevalence in Hospitalized Older Adults with Heart Failure in the United States (1998-2014)

Ariba Khan

78 Incidence Rates of CNS Drug-Induced Delirium – Results of AMSP – A Drug Surveillance Program Between 1993 and 2016

Michaela-Elena Friedrich

85 Clinical Utility of Constant Observation (One-to-One Special) in the Management of Delirium Khin Thu

82 Electronic Medical Record (EHR), Can It Help Hard of Hearing (HOH) Elderly Patients? Lindsey Boss

90 Pre-Hospital Leisure Activity is Associated with Reduced Delirium Incidence During Early Hospitalization: A Prospective Cohort Study

Michael Aboodi

Monday June 17, 2019 • 5:15-6:45pm • LOFT/STUDIO 2

Poster Moderator Discussion Groups (5:45-6:15pm)

23

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