JW MARRIOTT HOTEL, SAN FRANCISCO, CALIFORNIA

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Division of Cardiology Department of MedicineZuckerberg San Francisco General HospitalUniversity of California, San Francisco School of Medicine

Endorsed byAmerican College of Cardiology,California Chapter

35TH ANNUAL

ADVANCES IN HEART DISEASE

JW MARRIOTT SAN FRANCISCO UNION SQUARE SAN FRANCISCO, CALIFORNIA

COURSE DIRECTORPeter Ganz, MD, FACC

CO-DIRECTORSNora F. Goldschlager, MD, FACC Gabriel Gregoratos, MD, FACCBinh An P. Phan, MD, FACC

Our 35th annual course will again strive to present topics that highlight new evidence-based medicine findings reported within the last one to two years that impact clinical practice. These will range across a variety of cardiologic subspecialty interests including preventive cardiology, congenital heart disease, interventional cardiology, electrophysiology, cardiac imaging, cardiovascular pharmacotherapy, clinical cardiology, and cardiac surgery.Our faculty will include a distinguished group of visiting academicians from North America together with outstanding teachers and clinicians from the University of California,San Francisco. We plan to offer adequate time after each lecture to facilitate discussion with audience questions directed to the faculty.

TARGET AUDIENCE This course is intended for cardiovascular specialists, practicing cardiologists, internists, family physicians, cardiovascular and critical care nurses, and physician assistants.

This course is intended to facilitate changes in practice with respect to:• Providing the best management of coronary heart

disease, hypertension, lipid disorders, diabetes, systolic and diastolic heart failure, atrial fibrillation and flutter, STEMI and non-STEMI, thromboembolic disease;

• Refining considerations for atrial fibrillation, atrial flutter, and ventricular tachycardia ablation;

• Applying the best considerations of percutaneous interventions for stable coronary heart disease;

• Improving the use of anti-platelet and anti-coagulation therapy for cardiovascular diseases;

• Recognizing risk stratification of cardiovascular disease;

• Optimizing the management of peripheral artery disease;

• Recognizing that pathophysiology of diseases and treatment options differ among racial and ethnic groups;

• Optimizing the management of amyloidosis.

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JW MARRIOTT SAN FRANCISCO UNION SQUARE San Francisco, CA

35TH ANNUAL

ADVANCES IN HEART DISEASE

December 7-9, 2018ACCREDITATION The University of California, San Francisco School of Medicine (UCSF) is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.UCSF designates this live activity for a maximum of 17.00 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.This CME activity meets the requirements under California Assembly Bill 1195, continuing education and cultural and linguistic competency. Maintenance of Certification: Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 17.00 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification(MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.Nurses: For the purpose of recertification, the American Nurses Credentialing Center accepts AMA PRA Category 1 Credit™ issued by organizations accredited by the ACCME. Physician Assistants: AAPA accepts category 1 credit from AOACCME, Prescribed credit from AAFP, and AMA PRA category 1 credit™ from organizations accredited by the ACCME.Pharmacy:The California Board of Pharmacy accepts as continuing professional education those courses that meet the standard of relevance to pharmacy practice and have been approved for AMA PRA Category 1 Credit™. Family Physicians: Application for CME credit has been filed with the American Academy of Family Physicians. Determination of credit is pending.

general info

FRIDAY, DECEMBER 7, 20187:00 am Registration and Continental Breakfast

CHAIR: PETER GANZ, MD, FACC

8:10 Symposium Overview Peter Ganz, MD, FACC8:15 Inflammation in Cardiovascular Disease Peter Libby, MD, FACC 9:00 Pregnancy – a Stress that Predicts Nisha Parikh, MD, MPH Future Cardiometabolic Outcomes9:45 Cardiovascular Disease in HIV Priscilla Hsue, MD, FACC 10:30 Coffee Break 10:45 CHIP: A Potent and Common Newly Recognized Peter Libby, MD, FACC Cardiovascular Risk Factor11:30 Wearable Diagnostic Medical Devices Gregory Marcus, MD, MAS, FACC

12:15 pm Lunch (On Your Own)

CHAIR: GABRIEL GREGORATOS, MD, FACC1:30 Decoding and Repairing Genetic Disease Bruce Conklin, MD2:15 Imaging Cardiac Structure and Function with MRI Rajesh Dash, MD, PhD3:00 Diabetes Drugs that Reduce CV Events Peter Ganz, MD, FACC3:45 Coffee Break 4:00 Debate– PCI is Not Useful in Stable CHD: Protagonist Rita Redberg, MD, FACC4:15 Debate– PCI is Not Useful in Stable CHD: Antagonist John S. MacGregor, MD, PhD, FACC 4:30 Debate– PCI is Not Useful in Stable CHD: Rita Redberg, MD, FACC

Rebuttal and Questions John S. MacGregor, MD, PhD, FACC5:00 pm Adjourn

SATURDAY, DECEMBER 8, 20187:30 am Continental Breakfast

CHAIR: PETER GANZ, MD, FACC8:10 Peripheral Artery Disease Joshua Beckman, MD, MS, FACC8:55 Wearable Defibrillators Byron Lee, MD, FACC9:40 Peripheral Artery Disease Cont. Joshua Beckman, MD, MS, FACC 10:25 Coffee Break 10:40 NOACs: Management of Bleeding and Reversal Mary Gray, MD

Christina S. Wang, PharmD

11:25 RAPAPORT LECTURE: Melvin Scheinman, MD, FACC Treatment of Cardiac Arrhythmias: Past, Present, and a Glimpse into the Future

12:10 pm Lunch (On Your Own)

CHAIR: MELVIN CHEITLIN, MD1:30 Advanced Imaging of Myocardial Perfusion and Ahmed A. Tawakol, MD Coronary Stenosis2:15 Epidemic of Substance Abuse and CV Manifestations Michael Crawford, MD, FACC3:00 Imaging Cardiovascular Inflammation Ahmed A. Tawakol, MD3:45 Coffee Break 4:00 Debate– Hypertension Guidelines: Protagonist Michael Crawford, MD, FACC4:15 Debate– Hypertension Guidelines: Antagonist Binh An P. Phan, MD, FACC4:30 Debate– Hypertension Guidelines: Michael Crawford, MD, FACC Rebuttal and Questions Binh An P. Phan, MD, FACC5:00 pm Adjourn

35TH ANNUAL

ADVANCES IN HEART DISEASE

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general info

35TH ANNUAL

ADVANCES IN HEART DISEASEJW MARRIOTT SAN FRANCISCO UNION SQUARESAN FRANCISCO, CA

SUNDAY, DECEMBER 9, 20187:30 am Continental Breakfast

CHAIR: PETER GANZ, MD, FACC8:10 The Ins and Outs of Genetic Testing for Cardiologists Robert L. Nussbaum, MD8:55 Cardiac Amyloidosis Van Selby, MD 9:40 Artificial Intelligence: Clinical Applications in Echocardiography Sithu Win, MD, MPH10:25 Reducing Heart Failure Readmissions Lucas Zier, MD 11:10 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Edward Gerstenfeld, MD, FACC Protagonist11:25 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Joshua D. Moss, MD Antagonist11:40 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Edward Gerstenfeld, MD, FACC Rebuttal and Questions Joshua D. Moss, MD12:00 pm Adjourn

GENERAL INFORMATION Advanced registration closes one (1) business day prior to start of course. Onsite registration fees, if applicable, will be applied after this date.HOW TO ENROLL Tuition: $625 Physicians

($675 after November 3, 2018) $425 Allied Health Professionals/

Residents/Fellows ($475 after November 3, 2018)

Payment may be made by Visa, MasterCard, AmEx or check. REGISTER VIA: Online: cme.ucsf.eduMail: Complete course registration form

and send with payment to: UCSF Office of Continuing Medical Education

P.O. Box 45368 San Francisco, CA 94145-0368

Fax: Fax completed registration form to: (415) 502-1795 (be sure to include your credit card number)

Phone: To register by phone or to inquire about registration status, please call (415) 476-5808.

On-Site Registration: Generally we are able to accommodate on-site registration at our courses. Please check our website for up-to-date information: cme.ucsf.edu

REFUND POLICY Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date.CONFERENCE LOCATION With a style all its own, the architecturally stunning JW Marriott San Francisco Union Square takes center stage in Union Square, the cultural heart of San Francisco. Step into a world of luxury, and walk across the street for the finest shopping and dining. A wide array of boutiques, galleries, museums and theaters are all within a few blocks.A block of guestrooms has been reserved at the special UCSF conference rate of $209/night. You are urged to make your reservations early. The cut-off date is November 15, 2018 or until the group room block is filled. After this date, rooms will be provided on a space-available basis only. To make hotel reservations on-line, go to cme.ucsf.edu and click on the hotel link in the Travel & Lodging section of the course webpage. If you prefer to telephone in your reservation, call 800-228-9290 and identify yourself as a member of this UCSF conference to receive the special rate.By staying at the host hotel, you help UCSF meet its contractual obligations and keep registration fees reasonable. Please take this into consideration when making your accommodation decisions.UCSF has negotiated special fares with airlines and car rental agencies. Please visit the TRAVEL AND LODGING section on the course webpage at cme.ucsf.edu for more information and discount codes.

£ Dr. £ Ms. £ Mr. £ Mrs.

_________________________________________________________________Last Name First M.I.

_________________________________________________________________Degree Specialty

_________________________________________________________________ Address

_________________________________________________________________ City State Zip

_________________________________________________________________Daytime Phone Fax

_________________________________________________________________Email Address Label Code Letter (see address label: example, A, B, C, D, etc.)______________

Would you like to be on our priority email list? £ Yes £ No

Date of birth to be used as OCME registrant number: ___ ___ /___ ___ / X X Month Day Please indicate if you have any special needs: _____________________________________

Registration Fees (Receipt/Confirmation will be mailed within two weeks): £ $625 Physicians

($675 after November 3, 2018)

£ $425 Allied Health Professionals/Residents/Fellows ($475 after November 3, 2018)

Make checks payable to UC RegentsPlease charge my credit card: £ Visa £ MasterCard £ AmEx for $ _________________________

_________________________________________________|________/_______Card # Expiration date___________________________________|______________________________Name on Card (Please Print) Authorized Signature

Refund Policy: Cancellations received in writing before the first day of the course will be refunded, less a $75 administrative fee. No refunds will be made on cancellations received after that date.Please check our website for up to date information on the course: cme.ucsf.edu

35TH ANNUAL ADVANCES IN HEART DISEASEDecember 7-9, 2018 JW Marriott San Francisco Union Square San Francisco, CA

MDM19A02

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NORTH BEACHPLAYGROUND

MICHELANGELOPLAYGROUND WASHINGTON

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GEORGE R.MOSCONE

RECREATIONCENTER

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MISSION CREEK

GHIRARDELLISQUARE

THECANNERY

CROOKEDSTREET

FORTMASONCENTER

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JUSTINHERMANPLAZA

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BROOKSHALL

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UNDERWATERWORLD AQUARIUMYOUTH

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WORLDTRADE CTR.

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GOLDENGATE UNIV.

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JW Marriott San FranciscoUnion Square515 Mason Street San Francisco, CA 94102 (415) 771-8600 www.marriott.com

Mail to : UCSF Office of CME P.O. Box 45368 San Francisco, CA 94145-0368 Fax: (415) 502-1795

Online registration: cme.ucsf.edu Registration Information: (415) 476-5808 Course Information: (415) 476-4251

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JW MARRIOTT SAN FRANCISCO UNION SQUARESAN FRANCISCO, CA

SUNDAY, DECEMBER 9, 20187:30 am Continental Breakfast

CHAIR: PETER GANZ, MD, FACC8:10 The Ins and Outs of Genetic Testing for Cardiologists Robert L. Nussbaum, MD8:55 Cardiac Amyloidosis Van Selby, MD 9:40 Artificial Intelligence: Clinical Applications in Echocardiography Sithu Win, MD, MPH10:25 Reducing Heart Failure Readmissions Lucas Zier, MD 11:10 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Edward Gerstenfeld, MD, FACC Protagonist11:25 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Joshua D. Moss, MD Antagonist11:40 Debate– Ablation of Atrial Fibrillation as First Line Therapy: Edward Gerstenfeld, MD, FACC Rebuttal and Questions Joshua D. Moss, MD12:00 pm Adjourn

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COURSE DIRECTORPeter Ganz, MD, FACC Chief, Division of Cardiology Zuckerberg San Francisco General Maurice Eliaser Distinguished Professor of Medicine University of California, San Francisco

CO-DIRECTORS Nora F. Goldschlager, MD, FACC Chief, Clinical Cardiology Zuckerberg San Francisco General Professor of Medicine University of California, San FranciscoGabriel Gregoratos, MD, FACC Professor of Medicine, Emeritus University of California, San FranciscoBinh An P. Phan, MD, FACCAssociate Professor of MedicineDirector, Inpatient Cardiology ServicesZuckerberg San Francisco GeneralUniversity of California, San Francisco

VISITING COURSE FACULTY

Joshua Beckman, MD,MS, FACCDirector, Vascular MedicineProfessor of MedicineVanderbilt University Medical CenterNashville, TNRajesh Dash, MD, PhDAssistant Professor of Cardiovascular MedicineCo-Director, Falk Cardiovascular MRI FacilityStanford University Medical CenterPalo Alto, CaliforniaPeter Libby, MD, FACCSenior Advisor, Center for Interdisciplinary Cardiovascular Sciences; Mallinckrodt Professor of Medicine, Harvard Medical School; Senior Physician, Brigham and Women’s HospitalBoston, Massachusetts

Ahmed A. Tawakol, MDAssociate Professor of Medicine,Harvard Medical School Co-Director, Cardiac MR PET CT ProgramMassachusetts General HospitalBoston, MassachusettsCOURSE FACULTY(University of California, San Francisco unless indicated)Melvin Cheitlin, MDProfessor of Medicine, Emeritus Bruce Conklin, MDProfessor of MedicineSenior Investigator, Gladstone InstitutesMichael Crawford, MD, FACCProfessor of Medicine and Chief of Cardiology for Clinical ServicesEdward Gerstenfeld, MD, FACCMelvin Scheinman Endowed Professor of Medicine; Chief, Cardiac ElectrophysiologyMary Gray, MDProfessor of Medicine Medical Director, Anticoagulation ClinicPriscilla Hsue, MD, FACCWilliam Watt Kerr Professor of Medicine Director of Cardiovascular Research, Zuckerberg San Francisco GeneralByron Lee, MD, FACCProfessor of MedicineSamuel T. and Elizabeth WebbReeve Endowed Chair in Arrythmia ResearchDirector of Electrophysiology Laboratories and ClinicsJohn S. MacGregor, MD, PhD, FACCProfessor of MedicineDirector, Cardiac CatheterizationLaboratory and Interventional CardiologyZuckerberg San Francisco General

Gregory Marcus, MD, MAS, FACCProfessor of Medicine in ResidenceEndowed Professor in Atrial Fibrillation ResearchJoshua D. Moss, MDAssociate Professor of MedicineA.J. Stone—Dr. Francis L. Chamberlain Chair in CardiologyDirector, UCSF Cardiac Electrophysiology Fellowship ProgramRobert L. Nussbaum, MDProfessor of MedicineChief, Genomic MedicineCo-Director, Cardiovascular Genetics UCSF Heart and Vascular CenterNisha Parikh, MD, MPHAssistant Professor of Medicine, Adjunct SeriesDirector, Laboratory of Pregnancy and Cardiovascular DiseasesCardiology DivisionRita Redberg, MD, MS, FACCProfessor of MedicineDirector, Women’s Cardiovascular ServicesMelvin Scheinman, MD, FACCProfessor Emeritus of MedicineWalter H. Shorenstein Endowed Chair in CardiologyVan Selby, MDAssistant Professor of Medicine Director, UCSF Cardiac Amyloidosis ClinicChristina S. Wang, PharmDAnticoagulation and Cardiology Clinical Pharmacist, Zuckerberg San Francisco GeneralSithu Win, MD, MPHAssistant Professor of MedicineLucas Zier, MDAssistant Professor of Medicine Director, Structural Heart Disease Program, Zuckerberg San Francisco General

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