Ţesutul epitelial glandular - histology.rohistology.ro/histology/etg_files/3...
TRANSCRIPT
![Page 1: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/1.jpg)
EPITHELIAL TISSUE
Glandular epithelia
![Page 2: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/2.jpg)
Objectives
• Identifying glandular epithelia on the
histologic slides
• Differential diagnosis of exocrine
glands
![Page 3: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/3.jpg)
Glandular epithelia
• Epithelial cells specialized for synthesis
and secretion
• Secretory product is stored as secretory
granules
![Page 4: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/4.jpg)
Classification of glandular epithelia
• According to the destination of secretory
product
1. Exocrine
2. Endocrine
3. Mixed
![Page 5: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/5.jpg)
Glandular epithelia
1. EXOCRINE GLANDS
![Page 6: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/6.jpg)
• According to cell number:
– Unicellular: goblet cell
– Multicellular
• Secretory portion/parenchyma
• Excretory duct
Classification of exocrine glandular epithelia
![Page 7: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/7.jpg)
Classification of exocrine glandular epithelia - Simple Glands
![Page 8: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/8.jpg)
Classification of exocrine glandular epithelia - Compound Glands
![Page 9: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/9.jpg)
Goblet cells – unicellular exocrine gland
Small intestine, HE, ob. 40x Small intestine, PAS, ob.40x
![Page 10: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/10.jpg)
Intraepithelial gland, HE, ob. 40x
Nasal mucosa
![Page 11: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/11.jpg)
Longitudinal section, ob. 10x Cross section, ob. 20x
Simple columnar epithelium
Goblet cells
Simple tubular gland
Connective tissue
http://www.lab.anhb.uwa.edu.au/mb140/
Simple tubular glands, HE
Lieberkühn glands, large intestine
![Page 12: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/12.jpg)
Sweat gland, skin
Simple coiled tubular gland, HE, ob. 20x
http://www.lab.anhb.uwa.edu.au/
Secretory unit
Excretory duct
![Page 13: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/13.jpg)
Stomach –gastric glands
Simple branched tubular glands, col. HE, ob. 4x, 10x
![Page 14: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/14.jpg)
Sebaceous gland, skin
Simple acinar branched, HE, ob.10x
Epidermis
Dermis
![Page 15: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/15.jpg)
15 Simple acinar branched, HE, ob.10x
Sebaceous gland, skin
![Page 16: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/16.jpg)
Compound tubular, HE
Brunner glands, duodenum
![Page 17: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/17.jpg)
Compound tubulo-acinar, HE
Parotid Gland
![Page 18: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/18.jpg)
Serous acini, HE, ob.40x
Parotid Gland
![Page 19: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/19.jpg)
Mucous acini, HE, ob. 40x
Sublingual Gland
![Page 20: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/20.jpg)
Serous acini vs. Mucous acini
![Page 21: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/21.jpg)
Mixed acini, HE, ob.40x
Sublmandibular Gland
![Page 22: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/22.jpg)
Glandular epithelia
2. ENDOCRINE GLANDS
![Page 23: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/23.jpg)
Nests of endocrine epithelium, HE, ob. 20x
Adenohypophysis C- capilary, -nests
![Page 24: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/24.jpg)
Strands/cords of endocrine epithelia, HE, ob. 40x
Adrenal gland
![Page 25: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/25.jpg)
Ross HM, Histology: A Text and Atlas, 4th ed.
arrows – capilaries
Follicles, HE, ob.60x
Thyroid
![Page 26: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/26.jpg)
Glandular epithelia
3. MIXED GLANDS
![Page 27: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/27.jpg)
Compound acinar, HE
Exocrine pancreas
![Page 28: ŢESUTUL EPITELIAL GLANDULAR - histology.rohistology.ro/Histology/ETG_files/3 Epithelial_2_17.pdf · Glandular epithelia •Epithelial cells specialized for synthesis and secretion](https://reader030.vdocuments.us/reader030/viewer/2022021806/5bc2c77f09d3f291178cbe8a/html5/thumbnails/28.jpg)
Islet of Langerhans, HE
Endocrine pancreas