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Targos Biomarker Meeting 2013 February 25 – 26 Waldgut Schloss Höhnscheid Bad Arolsen – Höhnscheid Germany Targos (ɇFLHQWé5HOLDEOHé)OH[LEOH

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  • Targos Biomarker Meeting 2013February 25 26

    Waldgut Schloss HhnscheidBad Arolsen Hhnscheid Germany

    Targos

  • Welcom

    e to theTargos Biom

    arker Meeting 2013

    February 25-26, 2013W

    aldgut Schloss Hhnscheid,

    34454 Bad Arolsen Hhnscheid, G

    ermany

    Agenda

    Su

    nd

    ay, F

    eb

    ru

    ary 2

    4

    11.00 am 11.00 pm

    Arriv

    al o

    f pa

    rtic

    ipa

    nts

    6.00 - 9.00 pm

    Info

    rm

    al d

    inn

    er

    Mo

    nd

    ay, F

    eb

    ru

    ary 2

    5

    Mo

    de

    ra

    to

    r:

    U

    niversity of Southern California, Los Angeles. U

    SAV

    en

    ue

    :

    7.30 amB

    re

    ak

    fast

    9.00 amP

    ick

    -up, Travel to Targos by bus

    On bus:

    Intro

    du

    ctio

    n o

    f Ta

    rg

    os a

    nd

    Pa

    th

    olo

    gie

    No

    rd

    he

    sse

    n

    10.00 amArrival - Targos

    10.15 10.45 amTa

    rg

    os fa

    cilit

    y t

    ou

    r

    10.45 11.15 amP

    ath

    olo

    gie

    No

    rd

    he

    sse

    n fa

    cilit

    y t

    ou

    r

    11.15 11.30 amB

    RE

    AK

    11.30 12.00 noonIn

    tro

    du

    ctio

    n o

    f sp

    ea

    ke

    rs a

    nd

    ind

    ustry

    pa

    rtic

    ipa

    nts

    Targos

    12.00 12.45 pmLU

    NC

    H

  • 1.00 1.30 pmF

    DA

    pe

    rsp

    ectiv

    e o

    n p

    re

    dic

    tiv

    e

    bio

    ma

    rk

    ers

    University of Southern C

    alifornia Los Angeles, U

    SA

    1.30 2.00 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    ers in

    lym

    ph

    om

    as

    2.00 2.30 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    ers in

    me

    lan

    om

    a

    Center, H

    ouston, USA

    2.30 3.00 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    ers in

    bre

    ast c

    an

    ce

    r

    3.00 3.30 pmB

    RE

    AK

    3.30 4.00 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    ers a

    nd

    ge

    no

    mic

    stra

    te

    gie

    s fo

    r r

    atio

    na

    l co

    mb

    ina

    tio

    n o

    f

    ta

    rg

    ete

    d t

    he

    ra

    pie

    s

    4.00 4.30 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    er t

    estin

    g in

    Bra

    zil

    4.30 pmB

    us t

    o W

    ald

    gu

    t S

    ch

    loss H

    h

    nsch

    eid

    6.00 7.00 pmD

    INN

    ER

    7.00 8.30 pmD

    iscu

    ssio

    n a

    nd

    pe

    rsp

    ectiv

    e fr

    om

    ind

    ustry p

    artic

    ipa

    nts

    8.30 pmClose-out of the day at the fireplace

    Tu

    esd

    ay, F

    eb

    ru

    ary 2

    6

    Mo

    de

    ra

    to

    r:

    Ve

    nu

    e:

    Waldgut Schloss H

    hnscheid

    7.15 8.15 amB

    re

    ak

    fast

    8.30 9.00 amR

    ole

    of c

    en

    tra

    l pa

    th

    olo

    gy r

    ev

    iew

    in c

    linic

    al

    tra

    ils fo

    r b

    re

    ast c

    an

    ce

    r p

    atie

    nts

    9.00 9.30 amP

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    tiv

    e b

    iom

    ark

    ers in

    co

    lore

    cta

    l ca

    nce

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    9.30 10.00 amP

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    tiv

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    iom

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    ers in

    sto

    ma

    ch

    ca

    nce

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    10.00 11.00 amB

    RE

    AK

    / G

    ro

    up

    Ph

    oto

    11.00 11.30 amP

    re

    dic

    tiv

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    iom

    ark

    ers in

    NS

    CLC

    11.30 12.00 pmP

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    dic

    tiv

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    ark

    ers in

    SC

    LC

    /N

    SC

    LC

    Germ

    any

    12.00 12.30 pmP

    re

    dic

    tiv

    e b

    iom

    ark

    ers in

    sa

    rco

    ma

    s

    Center G

    ttingen

    12.30 1.30 pmLU

    NC

    H

    1.30 3.00 pmG

    en

    era

    l dis

    cu

    ssio

    n a

    nd

    wra

    p-u

    p o

    f me

    etin

    g

    3.00 pmC

    lose

    of t

    he

    bio

    ma

    rk

    er m

    ee

    tin

    g

  • Cliv

    e R

    oy T

    aylo

    r, MD

    , DP

    hil, M

    RC

    P (Ir

    ), FR

    CP

    ath

    University of Southern C

    alifornia, Los Angeles. USA

    --

    -

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ph

    ilipp

    e G

    au

    lard

    , MD

    malignancies. H

    e maintains an im

    portant practice of hematopathology

    comprising m

    any consultation cases, is the former m

    edical director of -gists from

    France and several neighbouring European countries conduc-

    lymphom

    a entities including primary m

    ediastinal large B-cell lymphom

    a

    to improve the diagnosis of lym

    phomas, and contribute to better m

    anage--

    national and international congresses.

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ale

    xa

    nd

    er L

    aza

    r, MD

    , Ph

    D

    pathogenesis, and targeted therapies for sarcoma &

    melanom

    a in the

    Center. H

    e is involved in multiple collaborative, laboratory-based re-

    ----

    lar modeling, he is focused on integrating m

    olecular markers into cancer

  • for reporting clinical molecular diagnostic testing in solid tum

    ors. On the

    authored more than 200 publications on num

    erous aspects of skin and -

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Su

    nil B

    ad

    ve

    , MD

    Sunil Badve received his medical degree and pathology residency at G

    rant --

    book chapters. He serves as the associate editor of C

    linical Breast Cancer

    speaker at national and international pathology meetings and has con-

    -

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Bria

    n L

    eyla

    nd

    -Jo

    ne

    s, M

    B B

    S, P

    hD

    recently served as associate vice president and director of the Emory

    at McG

    ill University in M

    ontreal, Canada.

    -

    -

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ve

    na

    ncio

    Ava

    ncin

    i Fe

    rre

    ira

    Alv

    es, M

    D, P

    hD

    of events from viral hepatitis and steato-hepatitis to cirrhosis to liver

  • biomarkers useful for diagnosis and, m

    ore recently , for targeted tumor

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Giu

    se

    pp

    e V

    iale

    , MD

    , FR

    CP

    ath

    Collaborative G

    roup Steering Com

    mittee, and he is Founding M

    ember of

    He has been active in clinical and translational researches on breast

    36 chapters in books

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Bh

    ara

    t J

    asa

    ni, M

    BC

    hB

    , Ph

    D, F

    RC

    Pa

    th

    -

    -tegic plans to m

    odernise histopathology service, and the development

    of diagnostic imm

    unocytochemistry &

    molecular pathology service in

    and standardisation of cancer biomarker analyses as the Breast C

    ancer -

    for translational research projects targeted at developing predictive bio-

    intra-operative method for sentinel lym

    ph node breast cancer metastases. -

    Medicine.

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Josef Rschoff, M

    D

  • -

    -

    Cancer Society.

    He has participated in m

    ore than 100 clinical trails pertaining to breast,

    -

    --led trial.

    -

    He is a recipient of m

    any grants and a consultant to some public

    corporations.

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ma

    nu

    el S

    alt

    o-T

    elle

    z, M

    D, F

    RC

    Pa

    th

    and genotype in both diagnostics and translational research.

    in many national and international conferences. H

    is areas of diagnostic in-terest are gastrointestinal pathology and m

    olecular diagnosis. His areas of

    research interest include the discovery and validation of novel molecular

    biomarkers of disease, the validation and technology transfer of novel dis-

    coveries into the molecular diagnostic practice and the m

    olecular patho-

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Re

    inh

    ard

    B

    ttn

    er, M

    D

  • in high-impact journals. Som

    e representative publications since 2010 are;

    integrative genome analyses and Science Transl M

    ed, in press 2012 ;

    and public corporations.

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ph

    ilipp

    Str

    be

    l, MD

    -

    of imatinib and sunitinib in thym

    ic carcinomas and co-authorships in m

    any

    -

    thology at the University M

    edical Center M

    annheim, U

    niversity of Heidel-

    Center G

    ttingen. His m

    ain research interests are molecular pathology

  • Jo

    hn

    Lo

    we

    , MD

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ha

    rtm

    ut K

    oe

    pp

    en

    , MD

    , Ph

    D

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Dr. H

    .-J. G

    ro

    te

    Head of H

    istopathology in Biomarker Technologies at M

    erck KGaA

    , Germ

    any

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    We

    rn

    er K

    ro

    ll. Glo

    ba

    l He

    ad

    of R

    ese

    arch

    . MD

    x.

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Pila

    r G

    arin

    -Ch

    esa

    , MD

    , Ph

    D

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Ha

    ra

    ld B

    ern

    ing

    er

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    Dr. B

    rb

    el P

    orstm

    an

    n

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

    He

    nrik

    Win

    th

    er, D

    VM

    , Ph

    D

    - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

  • About Targos

    -m

    ent and application of clinical biomarkers for the international pharm

    a-ceutical and diagnostic industry.

    The company has supported m

    ore than 100 international clinical trials

    pathologists is embedded in a professional environm

    ent of project ma-

    -tory im

    provement program

    s.

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  • 2011 European Frost &

    Service Leadership

    Targos

    Germaniastrasse 7

    [email protected] Tel: +49-561-50045300