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Title Dr First Name Tapasya Last Name Srivastava Photograph Designation Assistant Professor

Department Department of Genetics Address Room 313 , Department of Genetics, University of

Delhi South Campus, Benito Juarez Road, New Delhi - 110021

Phone No Office Residence

011-24157338, 011-24157155

Mobile Fax 011-24112761 Email tapasya@south.du.ac.in Web-Page bit.ly/TSlab

Educational Subject Institution Year Details PhD All India Institute of

Medical Sciences 2004

MSc Biochemistry Hamdard University 1998 1st division BSc (hon) Zoology Delhi University 1996 1st division Career Profile Organization / Institution Designation Duration Role AIIMS AIIMS

Ext-SRF Research Associate

One year (2004-2005) One year (2008-2009)

Research Research

AIIMS Young Scientist Fellow Three years (2005-2008) Research Delhi University, South Campus

Faculty Since Oct 2009 Teaching and thesis supervision of MSc, MPhil and PhD students

Research Interests / Specialization Biology of cancer cells in hypoxic tumor microenvironment Cancer genetics and risk markers Cancer therapeutics DNA methylation and epigenetic regulation in cancer cells Teaching Experience (Subject / Courses Taught) Regulation of gene expression / Epigenetic regulation in various model organisms Cell Biology and Biochemistry / Biochemistry Immunology Cancer Biology and Genetics Molecular Biology/ Replication, Repair and Recombination Research Methodology Honors & Awards Electedmember,NationalAcademyofMedicalSciences

SERBWomen’sExcellenceinscienceresearchaward2013

INSAyoungscientistmedalaward2010inMedicalSciences

Tapasya Srivastava, PhD

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RESEARCH GUIDANCE: PhD students: Completed : 3 Submitted: 1 Ongoing: 3 M.Phil students: Completed: 2 I. Research papers published in Refereed/Peer Reviewed Journals: (LAST FIVE YEARS only)

• SinghP,JenkinsLM,HorstB,AlersV,PradhanS,KaurP,SrivastavaT,HempelN,GyőrffyB,BroudeEV,LeeNY,MythreyeK.Inhibinisanovelparacrinefactorfortumorangiogenesisandmetastasis.CancerRes.2018Mar13.pii:canres.2316.2017.doi:10.1158/0008-5472.CAN-17-2316.[Epubaheadofprint]PubMedPMID:29535220.

• PandeyN, Pal S, Sharma LK,GuleriaR,MohanA,SrivastavaT*. SNP rs16969968as a StrongPredictorofNicotineDependenceandLungCancerRiskinaNorthIndianPopulation.AsianPacJCancerPrev.2017Nov26;18(11):3073-3079.PubMedPMID:29172281;PubMedCentralPMCID:PMC5773793.

• PrasadP,MittalSA,ChongthamJ,MohantyS,SrivastavaT*.Hypoxia-MediatedEpigeneticRegulationofStemnessinBrainTumorCells.StemCells.2017Jun;35(6):1468-1478.

• PradhanS,MahajanD,KaurP,PandeyN,SharmaC,SrivastavaT*.Combinationtreatmentoflowdosecisplatinandscriptaidovercomeshypoxia-inducedchemo-resistanceinlungcancercells.Oncotarget2016Nov1;7(44):71841-71855

• Pandey N, Dhiman S, Srivastava T*, Majumder S*. Transition metal oxide nanoparticles are effective ininhibiting lung cancer cell survival in the hypoxic tumormicroenvironment. Chem Biol Interact. 2016 Jul25;254:221-30.

• Mittal S, Pradhan S andSrivastava T*,Recent advances in targeted therapy for glioblastoma,Expert RevNeurother.ExpertRevNeurother.2015;15(8):935-46.

• TyagiG,PradhanS,SrivastavaT*andMehrotraR*,Nucleicacidbindingpropertiesofallicin;spectroscopicanalysisandestimationofanti-tumorpotential,BiochemicaandBiophysicaacta,1840(1),350-356,2014.

• SrivastavaT,BiolMedJ2014,6:1,Editorial.Nowperceiving:Thecompletegenomepackage.

II. Other than refereed /Peer Reviewed Journals Books / Chapter in book (last five years only)

TSrivastavaandLMSrivastava;ComplementSystem;TextbookofBiochemistry,Biotechnology,AlliedandMolecularMedicine;ed:GPTalwar,SEHasnainandSKSarin;Prentice-HallofIndiaPvtLtd,NewDelhi4thedition,2016:1227-1237.

Conference Presentations / Invited lectures As Invited Speaker at National seminar on Genes,Genetics and Epigenomics being organised by Human Genetics department, Guru Nanak Dev University, Amritsar on March 20,2018. As Invited Speaker at World Neurocongress-2017, Aligarh Muslim University, Aligarh, 9th and 10th December, 2017 As Invited Speaker at Annual Meeting of Indian Academy of Neurosciences in Odisha from October 29-31, 2017 As Invited Speaker at 1st international conference on ‘Human Implications of Biotechnology’, Centre for Biological Sciences, Central University of South Bihar held from 12th to 14th February 2016

As Invited Speaker at 12th International Conference of Asian Clinical Oncology Society (ACOS) and 35th Annual Convention of Indian Association for Cancer Research , New Delhi held on 8th April to 10th April, 2016. Professional Societies Memberships Member of Indian Association of Cancer Research Member, Institutional Ethics Committee, CCRH, Ministry of Health. Member, Institutional Ethics Committee, Delhi University South Campus Member, Institutional Committee on Stem Cell Research, Delhi University South Campus

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Member, Institutional Committee on Stem Cell Research, National Institute of Immunology Project (Major/Grants/Collaborations) ONGOING RESEARCH PROJECTS:

Elucudating the molecular basis and functional relevance of hypoxia-mediated aberrant methylation in glioma cells funded by SERB

COMPLETED RESEARCH PROJECTS: • Role of HDAC inhibitor(s) in modulating the response to chemotherapeutic agent(s) in cancer cells funded by

DST • Hypoxia induced stemness characteristics in brain tumor cells via active DNA methylation. Science and

Engineering Research Board, Ministry of Science and Technology. • Specificity and complexity of Integrin actin signaling in tumor cells funded by DBT • Targeting the tumor microenvironment: quest for novel targets for cancer therapy funded by ICMR

Signature of Faculty Member (Signature & Stamp of Head of the Department)